ABCC7/CFTR Expression Is Associated with the Clinical Course of Ulcerative Colitis Patients
Gastroenterol Res Pract. 2021 Aug 31;2021:5536563. doi: 10.1155/2021/5536563. eCollection 2021.ABSTRACTInflammatory bowel disease includes ulcerative colitis (UC) and Crohn's disease (CD) of unknown etiology. The expression of ATP-binding cassette (ABC) family proteins has been associated with drug resistance and development of UC. The cystic fibrosis transmembrane conductance regulator (CFTR) or also known as ABCC7 is involved in the inflammatory chronic response. The aim of this study was to evaluate the role of ABCC7/CFTR in UC patients and normal controls without inflammation. This is an exploratory, observational, and...
Source: Gastroenterology Research and Practice - September 13, 2021 Category: Gastroenterology Authors: Marco A Villeda-Ram írez Daniela Meza-Guillen Rafael Barreto-Z úñiga Jes ús K Yamamoto-Furusho Source Type: research

Comparison of Surgical Outcomes for Finsterer and the Roux-en-Y Reconstruction after Distal Gastrectomy for Gastric Carcinoma
CONCLUSION: The Finsterer and Roux-en-Y methods proved to be equally effective in their feasibility and safety. However, the Roux-en-Y method was better than the Finsterer method at limiting bile reflux and gastritis.PMID:34497642 | PMC:PMC8419505 | DOI:10.1155/2021/5562776 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - September 9, 2021 Category: Gastroenterology Authors: Pham Hoang Ha Nguyen Xuan Hoa Source Type: research

Value of Magnifying Chromoendoscopy and Magnifying Optical Enhancement Technology in Classifying Colorectal Polyps: A Prospective Controlled Study
This study is aimed at comparing the differential diagnostic value of ME-CE and OE for neoplastic and nonneoplastic polyps. Patients and Methods. Consecutive patients undergoing colonoscopy were randomized (1 : 1) into examination by ME-OE or ME-CE. Histopathological findings were utilized as the reference standard. Accuracy, sensitivity, specificity, and positive and negative predictive values of two endoscopy methods were compared using ME-OE (were classified according to the JNET classification) and ME-CE (were classified according to the Kudo pit pattern classification), respectively, and the time to predict the histol...
Source: Gastroenterology Research and Practice - September 6, 2021 Category: Gastroenterology Authors: Ying-Hao Song Ruo-Xin Xu Yong Zhang Meng-Xuan Xing Li-Dong Xu Kun-Kun Li Xing-Guo Xiao Lu Li Yan-Jing Xiao Yu-Lei Qu Ying-Jie Ma Bao-Hui Jia Hui-Li Wu Source Type: research

The Role of T Follicular Helper Cells and Interleukin-21 in the Pathogenesis of Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 23;2021:9621738. doi: 10.1155/2021/9621738. eCollection 2021.ABSTRACTT follicular helper (Tfh) cells represent a novel subset of CD4+ T cells which can provide critical help for germinal center (GC) formation and antibody production. The Tfh cells are characterized by the expression of CXC chemokine receptor 5 (CXCR5), programmed death 1 (PD-1), inducible costimulatory molecule (ICOS), B cell lymphoma 6 (BCL-6), and the secretion of interleukin-21 (IL-21). Given the important role of Tfh cells in B cell activation and high-affinity antibody production, Tfh cells are involved in the pathoge...
Source: Gastroenterology Research and Practice - September 2, 2021 Category: Gastroenterology Authors: Lulu Sun Ruixue Kong Hua Li Dashan Wang Source Type: research

FASN Knockdown Inhibited Anoikis Resistance of Gastric Cancer Cells via P-ERK1/2/Bcl-xL Pathway
This study investigated the role of FASN in the AR of GC cells. Plates coated with poly-HEMA were used for the culture of cells with AR. Small interfering RNA targeting FASN (siFASN) was transfected into MNK-45 and AGS cells. The number and apoptosis of cells were assessed by a hemacytometer and Annexin-V-FITC/PI assay, respectively. Aggregated cells and colony numbers were manually counted under a microscope. The migration and invasion rates were measured via wound healing and Transwell invasion assays, respectively. The levels of FASN, phosphorylated (p)-ERK1/2, ERK1/2 and Bcl-xL were detected through western blot or qua...
Source: Gastroenterology Research and Practice - August 30, 2021 Category: Gastroenterology Authors: Li Yu Xin Wang Yao Du Xiaowen Zhang Yunzhi Ling Source Type: research

TMEM100 Modulates TGF- < em > β < /em > Signaling Pathway to Inhibit Colorectal Cancer Progression
CONCLUSION: TMEM100 is lowly expressed in CRC, which can suppress CRC cell growth by regulating the TGF-β signaling pathway.PMID:34422038 | PMC:PMC8373494 | DOI:10.1155/2021/5552324 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 23, 2021 Category: Gastroenterology Authors: Huixia Li Chuan Cheng Weibo You Jiujian Zheng Jie Xu Peng Gao Jianping Wang Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Age and Gender: Affecting the Positive Rates of Serum PAB and ANCA in Patients with Inflammatory Bowel Disease
Gastroenterol Res Pract. 2021 Aug 4;2021:4963641. doi: 10.1155/2021/4963641. eCollection 2021.ABSTRACTInflammatory bowel disease (IBD) is a group of immune-mediated conditions. Immune activity is varied by age and gender. The present study is aimed at investigating the effect of age and gender on the positive rates of anti-Saccharomyces cerevisiae antibodies (ASCA), anti-neutrophil cytoplasmic antibodies (ANCA), anti-intestinal goblet cell antibodies (GAB), and antibodies to exocrine pancreas (PAB) in IBD patients. A total of 1871 hospitalized patients with confirmed IBD were included in this study. Sera were obtained from...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Qingquan Chen Shirong Huang Yue Wu Shuyu Zhang Qicai Liu Min Chen Source Type: research

Pleckstrin-2 as a Prognostic Factor and Mediator of Gastric Cancer Progression
Gastroenterol Res Pract. 2021 Aug 4;2021:5527387. doi: 10.1155/2021/5527387. eCollection 2021.ABSTRACTPleckstrin-2 (PLEK2) is a crucial mediator of cytoskeletal reorganization. However, the potential roles of PLEK2 in gastric cancer are still unknown. PLEK2 expression in gastric cancer was examined by western blotting and real-time PCR. Survival analysis was utilized to test the clinical impacts of the levels of PLEK2 in gastric cancer patients. In vitro and in vivo studies were used to estimate the potential roles played by PLEK2 in modulating gastric cancer proliferation, self-renewal, and tumourigenicity. Bioinformatics...
Source: Gastroenterology Research and Practice - August 16, 2021 Category: Gastroenterology Authors: Jun Wang Zhigang He Bo Sun Wenhai Huang Jianbin Xiang Zongyou Chen Zhenyang Li Xiaodong Gu Source Type: research

Endoscopic Treatment as the Rescue Therapy for Recurrent Bleeding after Transjugular Intrahepatic Portosystemic Shunt (TIPS)
CONCLUSION: Endoscopic treatment may be an option for recurrent bleeding after TIPS in selected patients. Further studies are needed to carefully define the indication and efficacy of this option.PMID:34381501 | PMC:PMC8352698 | DOI:10.1155/2021/6627837 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Liyuan Ni Xiaoquan Huang Siyu Jiang Lili Ma Jianjun Luo Shiyao Chen Source Type: research

Long Noncoding RNA MIR100HG Knockdown Attenuates Hepatocellular Carcinoma Progression by Regulating MicroRNA-146b-5p/Chromobox 6
CONCLUSIONS: Knockdown of MIR100HG inhibited the viability, migration, and invasion of HCC cells by targeting the miR-146b-5p/CBX6 axis, offering a potential therapeutic target for HCC therapy.PMID:34381502 | PMC:PMC8352691 | DOI:10.1155/2021/6832518 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Fushun Li Xianghua Sun Qing Liu Xilu Liu Jia Zhang Source Type: research

Endoscopic Treatment as the Rescue Therapy for Recurrent Bleeding after Transjugular Intrahepatic Portosystemic Shunt (TIPS)
CONCLUSION: Endoscopic treatment may be an option for recurrent bleeding after TIPS in selected patients. Further studies are needed to carefully define the indication and efficacy of this option.PMID:34381501 | PMC:PMC8352698 | DOI:10.1155/2021/6627837 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Liyuan Ni Xiaoquan Huang Siyu Jiang Lili Ma Jianjun Luo Shiyao Chen Source Type: research

Long Noncoding RNA MIR100HG Knockdown Attenuates Hepatocellular Carcinoma Progression by Regulating MicroRNA-146b-5p/Chromobox 6
CONCLUSIONS: Knockdown of MIR100HG inhibited the viability, migration, and invasion of HCC cells by targeting the miR-146b-5p/CBX6 axis, offering a potential therapeutic target for HCC therapy.PMID:34381502 | PMC:PMC8352691 | DOI:10.1155/2021/6832518 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Fushun Li Xianghua Sun Qing Liu Xilu Liu Jia Zhang Source Type: research

Endoscopic Treatment as the Rescue Therapy for Recurrent Bleeding after Transjugular Intrahepatic Portosystemic Shunt (TIPS)
CONCLUSION: Endoscopic treatment may be an option for recurrent bleeding after TIPS in selected patients. Further studies are needed to carefully define the indication and efficacy of this option.PMID:34381501 | PMC:PMC8352698 | DOI:10.1155/2021/6627837 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Liyuan Ni Xiaoquan Huang Siyu Jiang Lili Ma Jianjun Luo Shiyao Chen Source Type: research

Long Noncoding RNA MIR100HG Knockdown Attenuates Hepatocellular Carcinoma Progression by Regulating MicroRNA-146b-5p/Chromobox 6
CONCLUSIONS: Knockdown of MIR100HG inhibited the viability, migration, and invasion of HCC cells by targeting the miR-146b-5p/CBX6 axis, offering a potential therapeutic target for HCC therapy.PMID:34381502 | PMC:PMC8352691 | DOI:10.1155/2021/6832518 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Fushun Li Xianghua Sun Qing Liu Xilu Liu Jia Zhang Source Type: research

Endoscopic Treatment as the Rescue Therapy for Recurrent Bleeding after Transjugular Intrahepatic Portosystemic Shunt (TIPS)
CONCLUSION: Endoscopic treatment may be an option for recurrent bleeding after TIPS in selected patients. Further studies are needed to carefully define the indication and efficacy of this option.PMID:34381501 | PMC:PMC8352698 | DOI:10.1155/2021/6627837 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Liyuan Ni Xiaoquan Huang Siyu Jiang Lili Ma Jianjun Luo Shiyao Chen Source Type: research

Long Noncoding RNA MIR100HG Knockdown Attenuates Hepatocellular Carcinoma Progression by Regulating MicroRNA-146b-5p/Chromobox 6
CONCLUSIONS: Knockdown of MIR100HG inhibited the viability, migration, and invasion of HCC cells by targeting the miR-146b-5p/CBX6 axis, offering a potential therapeutic target for HCC therapy.PMID:34381502 | PMC:PMC8352691 | DOI:10.1155/2021/6832518 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 12, 2021 Category: Gastroenterology Authors: Fushun Li Xianghua Sun Qing Liu Xilu Liu Jia Zhang Source Type: research

Effect of Using Personal Protective Equipment during the COVID-19 Pandemic on the Quality Indicators of Screening Colonoscopies
CONCLUSION: Our study showed that quality indices for screening colonoscopies like CIR, CIT, and SWT were negatively impacted during the COVID-19 time period. ADR, however, was similar. Thus, the efficiency of the procedures was affected by the use of PPE but it did not affect the colonoscopy's clinical benefit.PMID:34373691 | PMC:PMC8349272 | DOI:10.1155/2021/8910004 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 10, 2021 Category: Gastroenterology Authors: Subin Chirayath Janak Bahirwani Parampreet Kaur Noel Martins Ronak Modi Source Type: research

The Partial Role of KLF4 and KLF5 in Gastrointestinal Tumors
CONCLUSION: KLF4 and KLF5 are of great significance for developing gastrointestinal tumors and can be used as therapeutic targets.PMID:34367275 | PMC:PMC8337138 | DOI:10.1155/2021/2425356 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 9, 2021 Category: Gastroenterology Authors: Jun-Chen Li Qiu-Han Chen Rui Jian Jiang-Rong Zhou Yun Xu Fang Lu Jun-Qiao Li Hao Zhang Source Type: research

Nomogram for Predicting Survival in Advanced Gastric Cancer after Neoadjuvant Chemotherapy and Radical Surgery
Gastroenterol Res Pract. 2021 Jul 28;2021:2923700. doi: 10.1155/2021/2923700. eCollection 2021.ABSTRACTBACKGROUND: Neoadjuvant chemotherapy (NAC) with subsequent radical surgery has become a popular treatment modality for advanced gastric cancer (AGC) worldwide. However, the survival benefit is still controversial, and prognostic factors remain undetermined.AIM: To identify clinical parameters that are associated with the survival of AGC patients after NAC and radical surgery and to establish a nomogram integrating multiple factors to predict survival.METHODS: We reviewed the medical profiles of 215 AGC patients who receiv...
Source: Gastroenterology Research and Practice - August 9, 2021 Category: Gastroenterology Authors: Yonghe Chen Dan Liu Jian Xiao Jun Xiang Aihong Liu Shi Chen Junjie Liu Xiansheng Hu Junsheng Peng Source Type: research

The Partial Role of KLF4 and KLF5 in Gastrointestinal Tumors
CONCLUSION: KLF4 and KLF5 are of great significance for developing gastrointestinal tumors and can be used as therapeutic targets.PMID:34367275 | PMC:PMC8337138 | DOI:10.1155/2021/2425356 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 9, 2021 Category: Gastroenterology Authors: Jun-Chen Li Qiu-Han Chen Rui Jian Jiang-Rong Zhou Yun Xu Fang Lu Jun-Qiao Li Hao Zhang Source Type: research

Nomogram for Predicting Survival in Advanced Gastric Cancer after Neoadjuvant Chemotherapy and Radical Surgery
Gastroenterol Res Pract. 2021 Jul 28;2021:2923700. doi: 10.1155/2021/2923700. eCollection 2021.ABSTRACTBACKGROUND: Neoadjuvant chemotherapy (NAC) with subsequent radical surgery has become a popular treatment modality for advanced gastric cancer (AGC) worldwide. However, the survival benefit is still controversial, and prognostic factors remain undetermined.AIM: To identify clinical parameters that are associated with the survival of AGC patients after NAC and radical surgery and to establish a nomogram integrating multiple factors to predict survival.METHODS: We reviewed the medical profiles of 215 AGC patients who receiv...
Source: Gastroenterology Research and Practice - August 9, 2021 Category: Gastroenterology Authors: Yonghe Chen Dan Liu Jian Xiao Jun Xiang Aihong Liu Shi Chen Junjie Liu Xiansheng Hu Junsheng Peng Source Type: research

Evaluation of the Prognostic Value of Red Cell Distribution Width to Total Serum Calcium Ratio in Patients with Acute Pancreatitis
CONCLUSIONS: RDW/TSC may be a new method to identify the AP patients who need to be transferred to the ICU, accompanying complications which need surgery treatment, or may be died in hospital at an early stage, and we should pay more attention to RDW/TSC in patients with AP, for they may have a worse prognosis.PMID:34354747 | PMC:PMC8331275 | DOI:10.1155/2021/6699421 (Source: Gastroenterology Research and Practice)
Source: Gastroenterology Research and Practice - August 6, 2021 Category: Gastroenterology Authors: Tian-Yong Han Tao Cheng Bo-Fu Liu Ya-Rong He Pan Pan Wen-Tao Yang None Qiang-Lai Yu Cao Source Type: research