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P174/304 CGuard stent in emergent settings- is the dual-layer stent safe? A multicenter study
ConclusionIn this multicenter study, the use of CGuard for emergent carotid artery stenting, particularly in tandem occlusions, was safe and resulted in lower rates of in-stent occlusions.Disclosure of InterestThe authors stated explicitly that there are no conflicts of interest in connection with this abstract.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Zidan, M., Voss, Y. L., Wolf, M., Christiane, K. F., Paech, D., Radbruch, A., Nordmeyer, H., Dorn, F. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P175/308 Analysis of demographic, procedural and imaging data of patients with acute arteriosclerotic tandem lesion: Age and stroke severity matters most for clinical outcome
ConclusionEVT for TL is safe and effective. Lower age and shorter procedural time both correlate with successful outcomes, but the fact that stroke severity, neurological issues and diabetes are linked to higher mortality shows the connotation of comorbidities with long-term survival.Disclosure of InterestAll authors: Nothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Huber, C., Gruber, P., Berberat, J., Sassenburg, R., Pflugi, S., Anon, J., Diepers, M., Andereggen, L., Kahles, T., Nedeltchev, K., Remonda, L. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

Modern endovascular management of chronic total carotid artery occlusion: technical results and procedural challenges
Conclusions In the modern endovascular era, revascularization of CTO is a feasible procedure in most cases, and it may be offered in selected patients. However, the high re-occlusion rate is still a limitation of the technique, underlining the need for more research on the technical procedural and periprocedural management.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Radu, R. A., Cagnazzo, F., Derraz, I., Dargazanli, C., Rapido, F., Lefevre, P.-H., Gascou, G., Costalat, V. Tags: New devices New devices and techniques Source Type: research

Retained radial catheters associated with variant radial anatomy in neurointerventional procedures
Conclusion Retained catheters for neurointerventional procedures performed via TRA are rare. However, this complication may be associated with variant radial anatomy. With the increased use of TRA for neurointerventional procedures, awareness of anatomical abnormalities that may lead to a retained catheter is necessary. We propose a simple protocol to avoid catheter entrapment, including in emergent situations such as TRA for stroke thrombectomy.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Catapano, J. S., Winkler, E. A., Srinivasan, V. M., Dishion, E. L., Rutledge, C., Baranoski, J. F., Cole, T. S., Rudy, R. F., Rumalla, K., Zomaya, M. P., Jadhav, A. P., Ducruet, A. F., Albuquerque, F. C. Tags: New devices New devices and techniques Source Type: research

Clinical evidence comparing bridging and direct endovascular thrombectomy: progress and controversies
This study aimed to analyze the progress and controversies in clinical evidence based on current meta-analyses. Three databases, including MEDLINE, EMBASE, and the Cochrane Library, were searched. Relevant data were extracted and reviewed from the pooled studies. The Assessment of Multiple Systematic Review (AMSTAR-2) was used for quality assessment. Twenty-five meta-analyses were finally included. There were 56% (14/25) from Asian countries, 20% (5/25) from North America, and 24% (6/25) from Europe. The majority (72%, 18/25) of evidence arose in a short period from 2020 to 2022 with the serial publication of four randomiz...
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Bai, X., Fu, Z., Wang, X., Song, C., Xu, X., Li, L., Feng, Y., Dmytriw, A. A., Regenhardt, R. W., Sun, Z., Yang, B., Jiao, L. Tags: Ischemic stroke Source Type: research

Onset-to-treatment time and aneurysmal regression predict improvement of cranial neuropathy after flow diversion treatment in patients with symptomatic internal carotid artery aneurysms
Conclusions The rate of cranial neuropathy symptom improvement after flow diversion increased over the first 12 months after treatment, but not thereafter. Treatment within 6 months of symptom onset and aneurysmal regression were predictors of symptom improvement.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Akiyama, R., Ishii, A., Kikuchi, T., Okawa, M., Yamao, Y., Abekura, Y., Ono, I., Sasaki, N., Tsuji, H., Imamura, H., Hatano, T., Sakai, N., Miyamoto, S. Tags: Open access, Hemorrhagic stroke Source Type: research

Flow diversion for compressive unruptured internal carotid artery aneurysms with neuro-ophthalmological symptoms: a systematic review and meta-analysis
Conclusion Flow diversion promotes recovery or improvement of compressive symptoms in a large proportion of patients but is associated with significant rates of morbidity and mortality. Transient and permanent NOS worsening is not uncommon. Early treatment is of utmost importance, as it increases the likelihood of symptom improvement more than 10-fold.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Kaiser, D. P. O., Cuberi, A., Linn, J., Gawlitza, M. Tags: Open access, Hemorrhagic stroke Source Type: research

Long-term outcomes of flow diversion for unruptured intracranial aneurysms: a systematic review and meta-analysis
Conclusion Flow diverters are safe and effective in short- and long-term follow-up and rarely cause serious delayed side effects.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Shehata, M. A., Ibrahim, M. K., Ghozy, S., Bilgin, C., Jabal, M. S., Kadirvel, R., Kallmes, D. F. Tags: Hemorrhagic stroke Source Type: research

Natural history, angiographic presentation and outcomes of anterior cranial fossa dural arteriovenous fistulas
Conclusion Most ACF-dAVFs have a symptomatic presentation. Drainage through cortical veins is a key angiographic feature of ACF-dAVFs that accounts for their malignant course. Microsurgery is the most effective treatment. Due to the high risk of bleeding, closure of ACF-dAVFs is indicated regardless of presentation.
Source: Journal of NeuroInterventional Surgery - August 17, 2023 Category: Neurosurgery Authors: Sanchez, S., Raghuram, A., Wendt, L., Hayakawa, M., Chen, C.-J., Sheehan, J. P., Kim, L. J., Abecassis, I. J., Levitt, M. R., Meyer, R. M., Guniganti, R., Kansagra, A. P., Lanzino, G., Giordan, E., Brinjikji, W., Bulters, D. O., Durnford, A., Fox, W. C., Tags: Hemorrhagic stroke Source Type: research

LB-004 Novel saccular endovascular aneurysm lattice (SEAL device) pre-seal it early clinical feasibility trial: procedural, 24-hours, and 3-month safety and effectiveness independent core lab adjudicated outcomes
ConclusionThe final procedural, 24-hour, and 3-month follow-up results of the PRE-SEAL-IT trial demonstrated promising occlusion rates at post-procedural, 24-hour, and 3 months follow-up with no safety concerns.DisclosuresB. Pabón: None. V. Torres: None. S. Zaidi: None. H. Salahuddin: None. M. Patiño: None. F. Peláez: None. J. Mútis: None. M. Cardozo: None. A. Hussain: None. I. Lutfi: None. M. Ali: None. S. Ahmed: None. E. Pereira: None. A. Badruddin: None. K. Woodward: None. T. Wolfe: None. C. Langerford: None. B. Jankowitz: None. V. Costalat: None. D. Altschell: None. M. Kaffashi: None. O. Zaidat: None.
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Pabon, B., Torres, V., Zaidi, S., Salahuddin, H., Patino, M., Pelaez, F., Mutis, J., Cardozo, M., Hussain, A., Lutfi, I., Ali, M., Ahmed, S., Pereira, E., Badruddin, A., Woodward, K., Wolfe, T., Langerford, C., Jankowitz, B., Costalat, V., Altschell, D., Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

LB-008 Treatment outcomes for ARUBA eligible brain arteriovenous malformations: a comparison of real-world data from the NVQI-QOD AVM registry to the ARUBA trial
ConclusionOur results suggest that intervention for unruptured brain AVMs at specialized centers across the United States is safe and effective.DisclosuresA. Alrohimi: None. R. Achey: None. R. Abdalla: None. T. Patterson: None. Y. Moazeni: None. P. Rasmussen: None. G. Toth: None. M. Bain: None. S. Ansari: None. S. Hussain: None. N. Moore: None.
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Alrohimi, A., Achey, R., Abdalla, R., Patterson, T., Moazeni, Y., Rasmussen, P., Toth, G., Bain, M., Ansari, S., Hussain, S., Moore, N. Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

LB-012 Incidence of intracranial hemorrhage after thrombectomy for large core infarcts: a sub analysis of the select2 trial
ConclusionIn a subset analysis of SELECT2 trial, patients receiving EVT had a higher rate of any intracranial hemorrhage when compared with those receiving medical management. Although EVT patients with ICH had a higher incidence of early neurological worsening, there was no difference in 90-day mRS, mortality and discharge dispositions between those with or without ICH.DisclosuresM. Chen: None. K. Joshi: None. B. Kolb: None. M. Hill: None. M. Abraham: None. A. Hassan: None. S. Ortega-Gutiérrez: None. M. Hussain: None. D. Pujara: None. C. Sitton: None. V. Pereira: None. M. Ribo: None. G. Albers: None. B. Campbell: N...
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Chen, M., Joshi, K., Kolb, B., Hill, M., Abraham, M., Hassan, A., Ortega-Gutierrez, S., Hussain, M., Pujara, D., Sitton, C., Pereira, V., Ribo, M., Albers, G., Campbell, B., Sarraj, A. Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

O-001 Trends in endovascular mechanical thrombectomy for acute ischemic stroke: a regional comparison analysis using United States national inpatient sample data
ConclusionsThere remain significant regional differences in the outcomes of EVT for AIS. More analysis is required to determine what is driving these differences. More work is needed to ensure optimal and equitable patient outcomes.Abstract O-001 Table 1 Characteristic (p value) East North Central East South Central Middle Atlantic Mountain New England Pacific South Atlantic West North Central West South Central Age in Years Mean (±SD)(p<0.001) 68.69 ± 14.43 67.04 ± 14.85 70.09 ± 14.39 68.72 ± 14.53 70.27 ± 14.92 70.26 ± 14.51 68.81 ± 14.29 69.21 ± 14.51 67...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brake, A., Fry, L., LeBeau, G., Heskett, C., Lei, C., Alkiswani, A., Le, K., De-Stefano, F., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-002 Safety and functional outcomes with early initiation of antiplatelet therapy following mechanical thrombectomy in emergent large vessel occlusion strokes: a single institution registry study
ConclusionsEarly AP initiation after MT in patients with AIS due to LVO was independently associated with significantly increased odds of better postoperative functional outcomes without increased odds of developing HT.Abstract O-002 Table 1Safety, clinical and functional outcomes: univariable analysis N=190 Early (<24 hours) (n=95) Late (>24 hours) (n=95) p-value Hemorrhagic TransformationSymptomaticAsymptomaticInpatient Mortality 25 (26.3)3 (3.2)22 (23.2)16 (16.8) 21 (22.1)8 (8.4)13 (13.7)23 (24.2) 0.4980.1200.0920.281 Discharge Modified Rankin Score*Functional Independence 4 (0-6)29 (30.5) 5 (0-6)14 (14.7) <.0...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Alexander, H., Claus, C., Tong, D., Kelkar, P., Griauzde, J., Teck, S., Richards, B. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-003 Comprehensive venous outflow predicts functional outcomes in acute ischemic stroke patients treated by thrombectomy
ConclusionsA new comprehensive VO score, inclusive of deep veins, was found to have a significantly greater association with functional independence at 90 days than COVES alone. A favorable CVO profile is strongly associated with functional independence and excellent post-thrombectomy reperfusion. Future studies should focus on patients with CVO status that is discrepant to eventual outcome.Abstract O-003 Figure 1Disclosures G. Adusumilli: None. T. Faizy: None. S. Christensen: 2; C; iSchemaView. 4; C; iSchemaView. M. Mlynash: None. Y. Loh: None. G. Albers: 2; C; iSchemaView, Genentech. 4; C; iSchemaView. M. Lansberg: None....
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Adusumilli, G., Faizy, T., Christensen, S., Mlynash, M., Loh, Y., Albers, G., Lansberg, M., Fiehler, J., Heit, J. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

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