O-002 Safety and functional outcomes with early initiation of antiplatelet therapy following mechanical thrombectomy in emergent large vessel occlusion strokes: a single institution registry study

ConclusionsEarly AP initiation after MT in patients with AIS due to LVO was independently associated with significantly increased odds of better postoperative functional outcomes without increased odds of developing HT.Abstract O-002 Table 1Safety, clinical and functional outcomes: univariable analysis N=190 Early (<24 hours) (n=95) Late (>24 hours) (n=95) p-value Hemorrhagic TransformationSymptomaticAsymptomaticInpatient Mortality 25 (26.3)3 (3.2)22 (23.2)16 (16.8) 21 (22.1)8 (8.4)13 (13.7)23 (24.2) 0.4980.1200.0920.281 Discharge Modified Rankin Score*Functional Independence 4 (0-6)29 (30.5) 5 (0-6)14 (14.7) <.001 0.015 30-day Postop Modified Rankin Score*Functional Independence* 4.05 (0-6)21 (22.1) 4.83 (0-6)6 (6.3) 0.011 0.006 90-day Postop Modified Rankin Score*Functional Independence* 4.03 (0-6)27 (28.4) 5.05 (0-6)17 (17.9) 0.024 0.102 Categorical data are presented as n (%); continuous data are presented as mean ± SD; TICI, Thrombolysis in Cerebral Infarction; Functional Independence is defined as mRS <2; p-value <0.05 considered significant.*Ordinal data are presented as median (range);no imputation was performed for mRS on discharge; imputations were performed for mRS and Functional Independence at 30 and 90 daysAbstract O-002 Table 2Safety and functional outcomes: multivariable analysis OR CI p-value Hemorrhagic Transformation Early Antiplatelet UseSexPreop tTPAThrombectomy site 1.380.900.950.31 0.65 - 2.910.45 - 1.810.46 ...
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: SNIS 20th annual meeting oral abstracts Source Type: research