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Source: Journal of NeuroInterventional Surgery
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Total 1069 results found since Jan 2013.

E-094 Higher intracranial positioning of 8fr-guide catheter improves efficacy of aspiration thrombectomy in large vessel occlusion stroke
ConclusionPositioning a large bore guide catheter within the petrous segment or further distal resulted in significantly higher rates of first pass effect, lower procedural times, lower total number of passes, and better rates of excellent recanalization.Disclosures M. Al-Kawaz: None. J. Milburn: None. D. Tomalty: None. K. Yaeger: None. D. Goldman: None. T. Hardigan: None. J. Scaggiante: None. M. Caton: None. H. Shoirah: None. T. Shigematsu: None. C. Kellner: 1; C; Research Funding from Penumbra and Siemens. S. Majidi: 2; C; Consultant for Rapid Medical, Cerenovus, Imperative Care.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Al-Kawaz, M., Milburn, J., Tomalty, D., Yaeger, K., Goldman, D., Hardigan, T., Scaggiante, J., Caton, M., Shoirah, H., Shigematsu, T., Kellner, C., Majidi, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-097 Acute ischemic stroke thrombus proteome is associated with time since last known well
ConclusionsThis study points, for the first time, to differences in the proteomic landscapes between thrombi from AIS patients that are related to time since symptom onset. Taken together, the present data support a view of the stroke thrombus as a living, dynamic microenvironment with increasing intracellular protein and RNA processing with increased tLKW. More work is required to further characterize early and late stroke thrombi, as a changing clot landscape may directly underlie responsiveness to treatment.Disclosures S. Akkipeddi: None. R. Rahmani: None. N. Ellens: None. G. Kohli: None. D. Schartz: None. S. Chittaranj...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Akkipeddi, S., Rahmani, R., Ellens, N., Kohli, G., Schartz, D., Chittaranjan, S., Bhalla, T., Mattingly, T., Morrell, C., Bender, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-098 Initial experience with the pipeline vantage flow diverter - vantage one study: six-month results, technical and clinical consideration
ConclusionThe new PVED reveals improved device visibility, ease of delivery and repositioning with precise distal opening in comparison to previous PED generations. Initial results demonstrate overall good device performance, safety profile and effectiveness. The implant requires a modified deployment technique for successful vessel wall apposition of the proximal stent as opposed to the previous generations of PED.ReferencesLylyk I, Scrivano E, Lundquist J, Ferrario A, Bleise C, Perez N, Lylyk PN, Viso R, Nella-Castro R, Lylyk P. Pipeline embolization devices for the treatment of intracranial aneurysms, single-center regi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: de Viliers, L., Carraro do Nascimento, V., Domitrovic, L., Rice, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-100 Rescue therapy with self-expandable stenting versus medical therapy after failed mechanical thrombectomy for acute large vessel occlusion stroke: a systematic review and meta-analysis
ConclusionOur study showed that, when compared to patients treated with best medical management, patients who received rescue therapy with SES after failed mechanical thrombectomy had a higher chances of functional independence, with lower mortality and similar sICH. However due to serious risk of bias and significant heterogeneity in the studies included, randomized trials using a standard technique and independently adjudicated outcomes are needed to confirm our results.Disclosures J. Sequeiros: None. F. Terry: None. S. Graham: None. N. Pacheco: None. M. Padilla: None. H. Zaver: None. C. Quispe: None. C. Cruzalegui: None...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Sequeiros, J., Terry, F., Graham, S., Pacheco, N., Padilla, M., Zaver, H., Quispe, C., Cruzalegui, C., Chavez, F., Pascual, M., Alva, C., Inoa, V., Hoit, D., Arthur, A., Goyal, N. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-105 Validation of rapid noncontrast stroke CT platform for ICH and LVO detection
ConclusionThe RAPID NCCT Stroke platform demonstrated superior performance to radiologists for detecting LVO from a NCCT. This could lead to earlier identification of LVO and faster treatment times. Prospective studies are needed for further validation.Abstract E-105 Table 1 Reader Description Hypothesis N Readers Rapid Reader SE (Readers) P value Average of all general radiologists Superiority 8 0.635 0.409 0.065 0.001 Average of all Readers Non-inferiority 11 0.635 0.436 0.055 <.0001 Average of neuroradiologists Non-inferiority 3 0.635 0.051 0.061 0.008 Disclosures V. Yedavalli: 2; C; RAPID (iSchemaview, Menlo Park, ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Yedavalli, V., Heit, J., Dehkharghani, S., Haerian, H., McMenamy, J., Honce, J., Timpone, V., Harnain, C., Kesselman, A., Filly, A., Beardsley, A., Sakamoto, B., Song, C., Montuori, J., Navot, B., Mena, F., Giurguitiu, D., Kitamura, F., Lima, F., Coelho, Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-107 Carotid artery stenting in patients with symptomatic non-stenotic carotid artery disease - a case series
ConclusionsIn this case series performed over a 10-year period at a high-volume stroke center we show that CAS is safe and efficient in patients with SyNC. Previous studies have established safety and effectiveness of CES in patients presenting with SyNC, however there is a paucity of reports in the literature regarding the effect of CAS in this patient population. Recent guidelines have brought specific attention to high-risk plaque characteristics which suggest that plaque instability plays a major role in the onset of ischemic events, regardless of lumen narrowing. Advanced imaging techniques, such as Optical Coherence ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Nedelcu, S., Kuhn, A., Singh, J., Puri, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-111 Repeat thrombectomy after large vessel occlusion stroke: incidence, clinical and technical outcomes
ConclusionsRepeat EVT for patients with re-occlusion within 30 days of thrombectomy is associated with favorable improvement in NIHSS, similar functional outcomes to patients undergoing single EVT, but has significantly higher risk of hemorrhagic conversion.Disclosures Y. Zohdy: None. H. Saad: None. B. Howard: None. C. Cawley: None. A. Pabaney: None. T. Garzon-Muvdi: None. I. Maier: None. A. Spiotta: None. P. Jabbour: None. S. Wolfe: None. A. Rai: None. J. Kim: None. J. Mascitelli: None. R. Starke: None. A. Shaban: None. S. Yoshimura: None. R. De Leacy: None. P. Kan: None. I. Fragata: None. A. Polifka: None. A. Arthur: Non...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Zohdy, Y., Saad, H., Howard, B., Cawley, C., Pabaney, A., Garzon-Muvdi, T., Maier, I., Spiotta, A., Jabbour, P., Wolfe, S., Rai, A., Kim, J., Mascitelli, J., Starke, R., Shaban, A., Yoshimura, S., De Leacy, R., Kan, P., Fragata, I., Polifka, A., Arthur, A Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-113 Lower low-density lipoprotein level increases the risk of delayed parenchymal hematoma following endovascular thrombectomy
ConclusionLDL level <50 mg/dL independently predicted delayed PH following thrombectomy and LDL >100 was shown to be a protective factor, irrespective of statin use. Further study is needed to explore the underlying mechanism and identify the strategies to prevent post-thrombectomy delayed PH among patients with low LDL levels.Disclosures S. Ahn: None. S. Roth: None. J. Jo: None. Y. Ko: None. N. Mummareddy: None. M. Fusco: None. R. Chitale: None. M. Froehler: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ahn, S., Roth, S., Jo, J., Ko, Y., Mummareddy, N., Fusco, M., Chitale, R., Froehler, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-115 Trans-radial versus trans-femoral access routes for diagnostic cerebral angiograms: a large single-center comparative cost-analysis study
ConclusionOverall, our study shows that the TR approach can be less a less expensive option for patients undergoing diagnostic cerebral angiograms, especially if complications occur. Future studies can corroborate our findings and potentially lead to the adoption of TR as a low-cost, efficient, gold-standard technique for cerebral angiography.Costs (dollars) Associated with Trans-Radial Versus Trans-Femoral AccessAbstract E-115 Table 1 Variable Trans-Femoral (n=314) Trans-Radial(n=612) P-value Total Cost, mean (SD) 12591.8 (19128) 12789.5 (18424) .88 Catheters, median (range) 12.4 (12.4-1900) 55.2 (12.4-369) .03 Closure d...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: El Naamani, K., Atallah, E., Momin, A., Jain, P., Hunt, A., Sambangi, A., Carreras, A., El Fadel, O., Gooch, M., Tjoumakaris, S., Zarzour, H., Schmidt, R., Herial, N., Rosenwasser, R., Jabbour, P. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-117 Mechanical thrombectomy for treatment of acute ischemic stroke in frail patients: a systematic review of literature
ConclusionMT for treatment of AIS in frail patients is associated with worse rates of morbidity and mortality along with reduced efficacy. More studies are needed to further evaluate and identify characteristics that may be more favorable to endovascular management in these patients.Disclosures N. Dabhi: None. J. Kumar: None. R. Kellogg: None. M. Park: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Dabhi, N., Kumar, J., Kellogg, R., Park, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-126 Multicenter flow diversion in 200 patients for treatment of intracranial aneurysms
ConclusionThis report characterizes patient demographics, aneurysm characteristics, procedure complications and long-term angiographic and clinical outcomes for a large patient population across multiple medical centers treated with flow diversion. Overall, procedures resulted in a high rate of occlusion and low rate of serious complications. Continued iterative outcomes analysis is warranted particularly as flow diversion technology evolves. Despite diverse hospital settings, differences in presentation, patient characteristics and the inclusion of off-label treatments, flow diversion procedures remained safe and effectiv...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Meister, R., Lesko, A., Marginean, H., Deshmukh, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-129 Trends in demographic and geographic disparities of stroke-related mortality in older adults in the United States from 1999 to 2020
Stroke is a leading cause of mortality and morbidity in the United States. Many risk factors are controversial, and their relative importance is not fully understood. Elucidating the association between demographic and geographic disparities and stroke-related mortality in older adults will guide policy to alleviate stroke burden. This retrospective cohort study characterizes stroke-related mortality among individuals aged 55 and older in the United States from January 1999 to December 2020 using the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database. Segmented regressio...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: McCandless, M., Powers, A., Baker, K., Strickland, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-135 Dejerine-roussy syndrome in the setting of right sigmoid sinus thrombosis: a unique case report
DiscussionThis case illustrates the important clinical aspects and physical findings needed to diagnose DRS. The presence of focal allodynia and hyperalgesia with recent cerebrovascular incidents provides significant evidence for DRS. The purpose of this case is to provide awareness and to increase clinical suspicion of DRS during examination, especially in the setting of cerebral venous sinus occlusion as infarction alone may not present as atypical allodynia.Disclosures S. Nittala: None. C. Jara: None. D. Raza: None. J. Cazzaniga: None. D. Filippi: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Nittala, S., Jara, C., Raza, D., Cazzaniga, J., Filippi, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-142 A new graphical interface to capture quantitative venous outflow metrics
ConclusionsOur newly developed graphical interface allows users to output quantitative metrics that may represent AIF and VOF. These metrics should be checked against existing scales for association and performance.Abstract E-142 Figure 1Disclosures G. Adusumilli: None. S. Christensen: 2; C; iSchemaView. 4; C; iSchemaView. T. Faizy: None. G. Albers: 2; C; iSchemaView, Genentech. 4; C; iSchemaView. M. Lansberg: None. J. Heit: 2; C; Medtronic, MicroVention. 6; C; iSchemaView.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Adusumilli, G., Christensen, S., Faizy, T., Albers, G., Lansberg, M., Heit, J. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research