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Source: Journal of NeuroInterventional Surgery
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Total 1069 results found since Jan 2013.

Early neurological improvement as a predictor of outcomes after endovascular thrombectomy for stroke: a systematic review and meta-analysis
Conclusions Broadly defined, ENI is a promising predictor of good functional outcome at 90 days and is associated with lower rates of mortality and sICH.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Kobeissi, H., Ghozy, S., Bilgin, C., Kadirvel, R., Kallmes, D. F. Tags: Editor''s choice, Ischemic stroke Source Type: research

Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device
Conclusion To our knowledge, this is the most extensive study to date that compares the treatment of different intracranial bifurcation aneurysms using the WEB device. Basilar tip and ICA bifurcation aneurysms showed significantly higher rates of aneurysm occlusion than other locations.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Adeeb, N., Dibas, M., Diestro, J. D. B., Phan, K., Cuellar-Saenz, H. H., Sweid, A., Lay, S. V., Guenego, A., Aslan, A., Renieri, L., Sundararajan, S. H., Saliou, G., Möhlenbruch, M., Regenhardt, R. W., Vranic, J. E., Lylyk, I., Foreman, P. M., Vac Tags: Hemorrhagic stroke Source Type: research

Bifurcation geometry remodelling of vessels in de novo and growing intracranial aneurysms: a multicenter study
Conclusion Our study suggests that wider bifurcation angles that have long been deemed causal factors for IA formation or growth may be secondary to IA formation at pathologic bifurcation sites. This finding has implications for our understanding of IA formation pathophysiology.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Boucherit, J., Kerleroux, B., Boulouis, G., Tessier, G., Rodriguez, C., Sporns, P. B., Ghannouchi, H., Shotar, E., Gariel, F., Marnat, G., Burel, J., Ifergan, H., Forestier, G., Rouchaud, A., Desal, H., Nouri, A., Autrusseau, F., Loirand, G., Bourcier, R. Tags: Hemorrhagic stroke Source Type: research

Associated genetic variants and potential pathogenic mechanisms of brain arteriovenous malformation
Conclusions According to our meta-analysis, ACVRL1 rs2071219 and CDKN2B-AS1 rs1333040 were potentially associated with bAVM. Multiple pathological signaling pathways could affect disease development. Future studies should aim to determine the interaction of candidate genes with environmental risk factors and to elucidate detailed mechanisms of action of variants and genes. 1
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Liu, J., Li, Y., Zhang, H., Luo, C., Yuan, D., Jiang, W., Yan, J. Tags: Hemorrhagic stroke Source Type: research

Relative versus absolute early neurological improvement after mechanical thrombectomy for large vessel occlusion stroke - hot or not?
Early clinical surrogates for long-term functional outcomes represent valuable clinical adjuncts. Lately, the National Institutes of Health Stroke Scale (NIHSS) score 24 hours after mechanical thrombectomy (MT) for large vessel occlusion (LVO) ischemic stroke has been repeatedly demonstrated to serve as a robust and independent predictor of 90-day functional outcomes.1–5 We read the article ‘Early neurological improvement as a predictor of outcomes after endovascular thrombectomy for stroke: a systematic review and meta-analysis’ by Kobeissi et al with great interest.6 Briefly, the authors synthesized nin...
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Hendrix, P., Schirmer, C. M. Tags: Letter Source Type: research

Betwixt and between: an idiomatic understanding of anesthesia in stroke intervention
After years of investigation, including substantial studies, opinions continue to shift regarding conscious sedation (CS) versus general anesthesia (GA) utilization in mechanical thrombectomy for emergent large vessel occlusion (ELVO) stroke. Early retrospective studies demonstrated that CS was superior,1 but subsequent randomized controlled trials failed to show the superiority of one method.2–4 Current research continues to explore the best use of anesthesia in acute ischemic stroke therapy.5–8 While consensus does not exist on whether CS or GA is safer and/or more beneficial for stroke interventions, there a...
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Milburn, J. M., Fiorella, D., Hirsch, J. A. Tags: Editor ' s column Source Type: research

Large core stroke thrombectomy: paradigm shift or futile exercise?
Predicting treatment effect is a popular topic among recent Journal of Neurointerventional Surgery stroke thrombectomy publications.1–3 The primary outcome measure is often functional independence, that is, a modified Rankin Scale (mRS) score of 0–2, which may lead practitioners to ruminate on the probability of this outcome during stroke triage, instead of treating patients with thrombectomy. The authors of this comment believe that the most current data no longer support that approach. Patients’ families do not wish to hear our estimates of the probability of independent function after treatment. They g...
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Chen, M., Leslie-Mazwi, T. M., Hirsch, J. A., Albuquerque, F. C. Tags: Commentary Source Type: research

Emergent carotid stenting versus no stenting for acute ischemic stroke due to tandem occlusion: a meta-analysis
Conclusions In observational studies, eCAS seems to be associated with higher good functional outcome than no-stenting in patients with acute ischemic stroke due to tandem occlusion, despite the higher risk of sICH. Dedicated trials are needed to confirm these results.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Diana, F., Romoli, M., Toccaceli, G., Rouchaud, A., Mounayer, C., Romano, D. G., Di Salle, F., Missori, P., Zini, A., Aguiar de Sousa, D., Peschillo, S. Tags: Ischemic stroke Source Type: research

Emergent microsurgical intervention for acute stroke after mechanical thrombectomy failure: a prospective study
Conclusions This study demonstrated the potential for existing microsurgical techniques to provide good outcomes in 58% of microsurgically treated patients as a third-tier option.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Fiedler, J., Roubec, M., Grubhoffer, M., Ostry, S., Prochazka, V., Langova, K., Skoloudik, D., for the EMIAS Study Group, Nevsimalova, Reiser, Sova, Hes, Masek, Bombic, Hurtikova, Krajca, Jonszta, Czerny Tags: Open access, Ischemic stroke Source Type: research

Determinants of cerebral aneurysm occlusion after embolization with the WEB device: a single-institution series of 215 cases with angiographic follow-up
Conclusion In this study we demonstrated that a width oversizing strategy of the WEB device was an independent predictor of aneurysm angiographic occlusion. Conversely, aneurysm height, irregular aneurysm, and WEB shape modification were all independent determinants of angiographic aneurysm remnant. These results may help to select aneurysms suitable for the WEB device and WEB sizing.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Cortese, J., Caroff, J., Chalumeau, V., Gallas, S., Ikka, L., Moret, J., Sabuzi, F., Popescu, S. D., Ozanne, A., Grimaldi, L., Mihalea, C., Spelle, L. Tags: Hemorrhagic stroke Source Type: research

Association between anesthesia modality and clinical outcomes following endovascular stroke treatment in the extended time window
Conclusion LA without sedation during EVT was associated with improved functional outcomes compared with GA, but not CS, within and beyond 6 hours from stroke onset. Prospective studies assessing anesthesia-related outcomes in the extended time window are warranted.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Dhillon, P. S., Butt, W., Podlasek, A., McConachie, N., Lenthall, R., Nair, S., Malik, L., Hewson, D. W., Bhogal, P., Makalanda, H. L. D., James, M. A., Dineen, R. A., England, T. J. Tags: Vascular neurology Source Type: research

Correlation of von Willebrand factor and platelets with acute ischemic stroke etiology and revascularization outcome: an immunohistochemical study
Conclusions The vWF level and CD42b/vWF distribution pattern in emboli were correlated with AIS etiology and revascularization outcome. Platelet content was associated with response to thrombolysis.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Mereuta, O. M., Abbasi, M., Arturo Larco, J. L., Dai, D., Liu, Y., Arul, S., Kadirvel, R., Hanel, R. A., Yoo, A. J., Almekhlafi, M. A., Layton, K. F., Delgado Almandoz, J. E., Kvamme, P., Mendes Pereira, V., Jahromi, B. S., Nogueira, R. G., Gounis, M. J., Tags: Basic science Source Type: research

Flow control in the middle cerebral artery during thrombectomy: the effect of anatomy, catheter size and tip location
Conclusion Choosing the biggest possible aspiration catheter and locating it in the middle cerebral artery significantly increases the chances of successful flow control. Flow through the collaterals may impair the flow, and circle of Willis anatomy should be considered during aspiration thrombectomy.
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Neidlin, M., Yousefian, E., Luisi, C., Sichtermann, T., Minkenberg, J., Hasan, D., Ridwan, H., Steinseifer, U., Wiesmann, M., Nikoubashman, O. Tags: Basic science Source Type: research

Endovascular coiling versus neurosurgical clipping for treatment of ruptured and unruptured intracranial aneurysms during pregnancy and postpartum period
Conclusions Most pregnant and postpartum patients are treated with EC for both ruptured and unruptured IA. For treatment of ruptured IA, EC is independently associated with a lower risk of perioperative ischemic stroke, but other in-hospital complications and mortality are comparable between EC and NC.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Garg, A., Elmashala, A., Roeder, H., Ortega-Gutierrez, S. Tags: Editor''s choice, Hemorrhagic stroke Source Type: research

Treatment of fusiform aneurysms with a pipeline embolization device: a multicenter cohort study
Conclusion PEDs may be an effective treatment for intracranial fusiform aneurysms, with a favorable occlusion rate. However, because these treatments have a relatively high rate of complications, PED treatment for fusiform aneurysms should be carefully and strictly controlled. Our analysis showed that PEDs with adjunctive coiling did not significantly improve the occlusion rate of fusiform aneurysms.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Turhon, M., Kang, H., Li, M., Liu, J., Zhang, Y., Zhang, Y., Huang, J., Luo, B., Liu, J., Zhang, H., Li, T., Song, D., Zhao, Y., Guan, S., Aximujiang, A., Maimaitili, A., Wang, Y., Feng, W., Wang, Y., Wan, J., Mao, G., Shi, H., Zhang, X., Gu, Y., Yang, X. Tags: Hemorrhagic stroke Source Type: research