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Source: Clinical Neurophysiology
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Total 151 results found since Jan 2013.

107. Ultrasound investigations in sickle cell anemia. Initial assessment and follow up
This study was proposed to compare two different equipment: TCD (trans-cranial doppler) and TCCS (transcranial color-coded sonography) with or without using the angular correction, in a group of patients with the sickle cell anemia in order to identify the most suitable technique for the sampling of blood velocity (TAMM). 35 pediatric patients without previus history of neurological disease or transfusion were enrolled. Arteries examined were the middle cerebral artery, the anterior cerebral artery, the posterior cerebral and the basilar arteries. TAMM values greater than 200cm/s identify patients at high risk of stroke wh...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: V. Marcon, G. Meneghetti, P. Rampazzo, M. Ermani Tags: Society Proceedings Source Type: research

87. Microembolic and haemodynamic events underlying periprocedural neuroradiological findings and neurological complications of Transfemoral Aortic Valve Implantation (TAVI): A Transcranial Doppler study design
Stroke and cognitive decline, due to periprocedural embolic and/or haemodynamic events, are the most feared neurological complications of Transfemoral Aortic Valve Implantation (TAVI). Transcranial Doppler (TCD) monitoring allows real time detection of such abnormalities, but their exact correlation with new-onset brain lesions and clinical findings has not been fully elucidated yet. Consecutive candidates to TAVI will be enrolled; patients with contraindications to MRI or inadequate transtemporal acoustic window will be excluded. Pre-procedurally, at discharge and at 3months follow-up, neurological examination (through NI...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: F. Sartucci, A. Chiti, N. Giannini, F. De Caro, G. Gialdini, E. Terni, E. Giorli, M. Puglioli, M. Cosottini, A.S. Petronio, G. Orlandi Tags: Society Proceedings Source Type: research

56. Effects of deep repetitive transcranial magnetic stimulation (rTMS) on motor function of paretic lower limb in chronic sub-cortical stroke: A pilot study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of stroke patients. The purpose of this double-blind placebo-controlled crossover study was to assess the efficacy of 20Hz rTMS delivered with H-coil on lower limb (LL) motor function in patients with chronic (>6months) subcortical stroke. Nine patients received both real and sham rTMS in a random sequence. rTMS treatments were composed of 11 sessions (administered over 3-weeks) and were separated by a 4-week wash-out period. LL functions were assessed by the Fugl-Meyer LL scale (FM-LL), the 10-meters walking t...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: R. Chieffo, S. De Prezzo, E. Houdayer, A. Nuara, L. Straffi, F. Spagnolo, D.Dalla Libera, G.Di Maggio, E. Coppi, L. Ferrari, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Tags: Society Proceedings Source Type: research

59. Alterations of the electroencephalographic rhythms in children with Sickle Cell disease (SCD): Source analysis with LORETA
Sickle Cell Disease (SCD) is a congenital familial pathology of the haemoglobin and it is classified as the most common genetic disease in the world.Neurological complications are very frequent: symptomatic stroke occurs in 11% of the SCD patients before they reach 20years of age, while 35% of the patients shows silent damages at the RMN with cognitive impairments and learning disabilities. The aim of this study is to verify the hypothesis that a different cerebral maturation between children with SCD and healthy controls exists. This has been achieved with the spectral analysis of electroencephalographic (EEG) rhythms and...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: A. Bertoldo, P. Rampazzo, R. Manara, R. Colombatti, L. Sainati, M. Ermani Tags: Society Proceedings Source Type: research

47. Botulinum toxin for the upper limb after stroke: Comparison between incobotulinumtoxin A, botulinum toxin drug free of complexing proteins, and conventional botulinum toxin formulation. A preliminary study
Botulinum toxin type A (BoNT/A) provides a valuable tool in the multi-modal treatment of spasticity. Incobotulinumtoxin A (InBoNT/A) is a highly purified BoNT/A agent, free of any complexing clostridial proteins.Clinical experience suggests that InBoNT/A is identical from efficacy, duration of therapeutic effect and tolerability profile. Our aim was to compare the effect of the CBoNT/A vs InBoNT/A on spasticity of the upper limb, evaluated with Modificated Aswhort Scale (MAS), and on amplitude of compound motor action potentials (CMAP) of biceps muscle in patients after brain stroke. A randomized, double-blind, parallel-gr...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: C. Cesaretti, A. Grippo, A. Vettori, T. Atzori, C. Baldini, C. Falsini, M. Martini, R. Carrai, A. Pizzi Tags: Society Proceedings Source Type: research

P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research

P 229. Transcranial Laser Stimulation-A New Method for Non-Invasive Modulation of Cortical Excitability
Conclusions: The M1 excitability was found to be reduced after TLS in dose dependent manner. These findings may give insight into the mechanisms of nirLLL effects in the human cerebral cortex, also suggesting more suitable applications of TLS in clinical settings.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Filipovic, M. Jelic, A. Jeremic, V. Stevanovic, S. Milanovic, L. Konstantinovic Tags: Society Proceedings Source Type: research

P 217. Analysis of cortical reorganization after stroke
Conclusion: MEP and rMT are informative criteria for defining the functional state of the motor cortex and features of cortical reorganization after stroke. The graduation of reducing excitability of the motor cortex of AH is proposed for use in clinical practice and could be considered in evaluation the prognosis after stroke.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Kuznetsova, N. Skachkova Tags: Society Proceedings Source Type: research

P 219. Navigated repeated transcranial magnetic stimulation in stroke rehabilitation (randomized blind sham-controlled study), Preliminary results: safety and tolerability
Conclusion: Repeated nTMS is safe and effective add-method in motor post-stroke rehabilitation, but continuous study and forming protocols are necessary to validate this method.ClinicalTrials.gov Identifier: NCT01652677.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: M. Piradov, L. Chernikova, M. Tanashyan, A. Kadykov, A. Chervyakov, M. Nazarova, V. Gnezditsky, R. Konovalov, N. Savitskaya, P. Fedin, A. Suslin, M. Glebov, L. Dobrynina Tags: Society Proceedings Source Type: research

P 194. The EEG correlates of the TMS induced EMG silent period in humans
Application of magnetic or electrical stimulation to the motor cortex can result in a period of electromyography (EMG) silence in a tonically active peripheral muscle. This period of EMG silence is referred to as the silent period (SP). The duration of SP shows intersubject variability and reflects the integrity of the cortical and corticospinal pathways. A non-invasive technique for assessing the duration of SP is the combination of Transcranial Magnetic Stimulation (TMS) with EMG. Utilizing TMS-EMG, several studies have reported on the shortening or lengthening of SP in neuropsychiatric disorders such as schizophrenia, b...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: F. Farzan, M.S. Barr, S. Hoppenbrouwers, P.B. Fitzgerald, R. Chen, A. Pascual-Leone, Z.J. Daskalakis Tags: Society Proceedings Source Type: research

P 181. Impact of offline transcranial direct current stimulation on consolidation of motor sequence learning in healthy elderly subjects
Conclusions: Offline application of anodal tDCS over M1 post training improves consolidation of motor sequence learning in elderly subjects until at least 22h post training. Further studies are needed to investigate the potential benefit of offline-tDCS in motor learning in healthy elderly and stroke patients.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: M. Wegscheider, J.-J. Rumpf, C. Fricke, D. Weise, J. Classen Tags: Society Proceedings Source Type: research

P 172. Focal tDCS in Chronic Stroke patients: A pilot study of physiological effects using TMS and concurrent EEG
We report results of MEPs, EEG, and motor behavior. We show, for the first time, that tDCS and EEG recording can be concurrently applied in stroke patients. Bilateral M1 stimulation using small Ag/AgCl electrodes is well tolerated and can augment corticospinal excitability in the affected hemisphere. In the literature, there is only one prior studying using concurrent EEG recording during cathodal tDCS in healthy subjects and two patients with epileptic encephalopathy (Faria et al., 2012). As far as we know, no studies have applied tDCS simultaneous with EEG recording in chronic stroke patients. We report the first study i...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: D. Boratyn, G. Ruffini, M. Cortes, A. Rykman, A. Medeiros, A. Pascual-Leone, D. Edwards Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research

P 162. The effects of direct current stimulation on motor cortex excitability in children and adolescents
Conclusion: Our study will provide new insight into the principles of tDCS stimulation and its therapeutic value in treatment of childhood neurological and psychiatric disorders. This may further refine the effective use of tDCS in pediatric population.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: V. Moliadze, T. Schmanke, S. Bassüner, C. Freitag, M. Siniatchkin Tags: Society Proceedings Source Type: research

P 126. Righthemispheric inhibitory rTMS in patients with letfsided brain infarcts: Effect on cerebral blood flow using PET and speech performance
Discussion: rTMS with inhibitory effect on the rightsided homologous speech area plus speech therapy in patients with left sided brain infarcts and aphasia results in better recovery of language performance compared to patients who received speech therapy only.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: A. Hartmann, I. Rubi-Fessen, W.-D. Heiß, L. Kracht, J. Kessler, T. Rommel Tags: Society Proceedings Source Type: research