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Source: Clinical Neurophysiology
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Total 151 results found since Jan 2013.

P 229. Transcranial Laser Stimulation-A New Method for Non-Invasive Modulation of Cortical Excitability
Conclusions: The M1 excitability was found to be reduced after TLS in dose dependent manner. These findings may give insight into the mechanisms of nirLLL effects in the human cerebral cortex, also suggesting more suitable applications of TLS in clinical settings.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Filipovic, M. Jelic, A. Jeremic, V. Stevanovic, S. Milanovic, L. Konstantinovic Tags: Society Proceedings Source Type: research

P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research

P 217. Analysis of cortical reorganization after stroke
Conclusion: MEP and rMT are informative criteria for defining the functional state of the motor cortex and features of cortical reorganization after stroke. The graduation of reducing excitability of the motor cortex of AH is proposed for use in clinical practice and could be considered in evaluation the prognosis after stroke.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Kuznetsova, N. Skachkova Tags: Society Proceedings Source Type: research

P 219. Navigated repeated transcranial magnetic stimulation in stroke rehabilitation (randomized blind sham-controlled study), Preliminary results: safety and tolerability
Conclusion: Repeated nTMS is safe and effective add-method in motor post-stroke rehabilitation, but continuous study and forming protocols are necessary to validate this method.ClinicalTrials.gov Identifier: NCT01652677.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: M. Piradov, L. Chernikova, M. Tanashyan, A. Kadykov, A. Chervyakov, M. Nazarova, V. Gnezditsky, R. Konovalov, N. Savitskaya, P. Fedin, A. Suslin, M. Glebov, L. Dobrynina Tags: Society Proceedings Source Type: research

P 181. Impact of offline transcranial direct current stimulation on consolidation of motor sequence learning in healthy elderly subjects
Conclusions: Offline application of anodal tDCS over M1 post training improves consolidation of motor sequence learning in elderly subjects until at least 22h post training. Further studies are needed to investigate the potential benefit of offline-tDCS in motor learning in healthy elderly and stroke patients.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: M. Wegscheider, J.-J. Rumpf, C. Fricke, D. Weise, J. Classen Tags: Society Proceedings Source Type: research

P 194. The EEG correlates of the TMS induced EMG silent period in humans
Application of magnetic or electrical stimulation to the motor cortex can result in a period of electromyography (EMG) silence in a tonically active peripheral muscle. This period of EMG silence is referred to as the silent period (SP). The duration of SP shows intersubject variability and reflects the integrity of the cortical and corticospinal pathways. A non-invasive technique for assessing the duration of SP is the combination of Transcranial Magnetic Stimulation (TMS) with EMG. Utilizing TMS-EMG, several studies have reported on the shortening or lengthening of SP in neuropsychiatric disorders such as schizophrenia, b...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: F. Farzan, M.S. Barr, S. Hoppenbrouwers, P.B. Fitzgerald, R. Chen, A. Pascual-Leone, Z.J. Daskalakis Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research

P 162. The effects of direct current stimulation on motor cortex excitability in children and adolescents
Conclusion: Our study will provide new insight into the principles of tDCS stimulation and its therapeutic value in treatment of childhood neurological and psychiatric disorders. This may further refine the effective use of tDCS in pediatric population.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: V. Moliadze, T. Schmanke, S. Bassüner, C. Freitag, M. Siniatchkin Tags: Society Proceedings Source Type: research

P 172. Focal tDCS in Chronic Stroke patients: A pilot study of physiological effects using TMS and concurrent EEG
We report results of MEPs, EEG, and motor behavior. We show, for the first time, that tDCS and EEG recording can be concurrently applied in stroke patients. Bilateral M1 stimulation using small Ag/AgCl electrodes is well tolerated and can augment corticospinal excitability in the affected hemisphere. In the literature, there is only one prior studying using concurrent EEG recording during cathodal tDCS in healthy subjects and two patients with epileptic encephalopathy (Faria et al., 2012). As far as we know, no studies have applied tDCS simultaneous with EEG recording in chronic stroke patients. We report the first study i...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: D. Boratyn, G. Ruffini, M. Cortes, A. Rykman, A. Medeiros, A. Pascual-Leone, D. Edwards Tags: Society Proceedings Source Type: research

P 114. Anodal transcranial direct current stimulation in early treatment of post-stroke non-fluent aphasia
Conclusions: The findings provide only a weak evidence of A-tDCS behavioural gains during early neurorehabilitation of post-stroke aphasia. Further research is needed to investigate the effectiveness of this kind of neuromodulation. Different modes and parameters of tDCS should be explored considering such important factors determining recovery from aphasia as type and severity of language impairment, lesion site and size, time since stroke, and degree of hemispheric language laterality.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: K. Polanowska, M. Leśniak, J. Seniów Tags: Society Proceedings Source Type: research

P 117. Can cerebellar theta burst stimulation improve recovery of cerebellar stroke patients?
Conclusion: These preliminary results provide novel evidence that cerebellar TBS can be used to promote functional recovery of patients with cerebellar stroke. These clinical improvement could be related to long-lasting changes in the excitability of cerebello-thalamo-cortical pathways.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: V. Ponzo, S. Bonnı̀, C. Caltagirone, G. Koch Tags: Society Proceedings Source Type: research

P 126. Righthemispheric inhibitory rTMS in patients with letfsided brain infarcts: Effect on cerebral blood flow using PET and speech performance
Discussion: rTMS with inhibitory effect on the rightsided homologous speech area plus speech therapy in patients with left sided brain infarcts and aphasia results in better recovery of language performance compared to patients who received speech therapy only.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: A. Hartmann, I. Rubi-Fessen, W.-D. Heiß, L. Kracht, J. Kessler, T. Rommel Tags: Society Proceedings Source Type: research

P 128. Predicting behavioural response to TDCS in chronic motor stroke
Transcranial direct current stimulation (TDCS) of primary motor cortex (M1) can transiently improve paretic hand function in chronic stroke. However, responses are variable so there is incentive to try to improve efficacy or to predict response in individual patients. Both excitatory (Anodal) stimulation of ipsilesional M1 and inhibitory (Cathodal) stimulation of contralesional M1 can speed simple reaction time. Here we tested whether combining these two effects simultaneously, by using a bilateral M1–M1 electrode montage, would improve efficacy. We tested the physiological efficacy of Bilateral, Anodal or Cathodal TDCS ...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: J. O’Shea, M.-H. Boudrias, C.J. Stagg, V. Bachtiar, J.U. Blicher, H. Johansen-Berg Tags: Society Proceedings Source Type: research

P 101. Transcranial direct current stimulation for improving function and activities of daily living in patients after stroke. First results of a systematic Cochrane-Review
Conclusion: Our review showed that in some studies tDCS might improve upper extremity function. However, it is still unclear if tDCS could improve generic ADL. Thus further research seems to be needed.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: B. Elsner, J. Kugler, M. Pohl, J. Mehrholz Tags: Society Proceedings Source Type: research

P 102. Transcranial direct current stimulation for improving aphasia after stroke. First results of a systematic Cochrane Review
Conclusion: Our review showed that in some studies tDCS might facilitate word retrieval after stroke and hence might improve aphasia. However, it is still unclear if tDCS could improve functional communication. Thus further research seems to be needed.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: B. Elsner, J. Kugler, M. Pohl, J. Mehrholz Tags: Society Proceedings Source Type: research