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Source: Clinical Neurophysiology
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Total 151 results found since Jan 2013.

87. Anodal transcranial direct current stimulation of motor cortex does not ameliorates spasticity in multiple sclerosis
Spasticity is a common disorder and a major cause of a long-term disability in patients with multiple sclerosis (MS). Transcranial direct current stimulation (tDCs) is a potential tool to improve motor deficits in several neurological disease and, recently, it has been proposed as effective in decreasing spasticity after stroke. To assess whether anodal tDCS is effective in modulating lower limb spasticity in MS patients. We performed a single-centre randomized, double-blind, sham-controlled study to investigate efficacy of anodal vs sham tDCs in 20 relapsing-remitting MS patients.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Iodice, F. Manganelli, L. Ruggiero, R. Dubbioso, L. Santoro Source Type: research

106. Deep repetitive transcranial magnetic stimulation (rTMS) with H-coil coupled with cycling in chronic lower limb dysfuncion after stroke: A randomized, placebo-controlled, crossover study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of post-stroke deficits. We evaluated the feasibility, safety and efficacy of excitatory Hz rTMS with H-coil over the leg motor areas combined with active cycling on paretic lower limb motor function in chronic post-stroke. rTMS was delivered with the H-coil targeting the lower limbs (real or sham for 11 sessions over 3weeks, with cross-over after 4weeks wash-out, in 12 subjects with first stroke more than 6months before.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Chieffo, F. Giatsidis, E. Houdayer, M. Fichera, A. Nuara, E. Coppi, L. Ferrari, G. Di Maggio, R. Santangelo, A. Poggi, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Source Type: research

112. Low frequency repetitive transcranial magnetic stimulation in early phase of rehabilitation of patients with post-stroke aphasia
About 50% of post-stroke patients remain aphasic a condition that greatly impede their reintegration to society. Results of Repetitive Transcranial Magnetic Stimulation (rTMS) as supplementary treatment for sub-acute post-stroke aphasia are controversial. We assessed the efficacy of inhibitory rTMS with conventional speech therapy to help recovery language performance in sub-acute stroke aphasia.In a randomised case-control double-blind study 12 non-fluent aphasic were consecutively enrolled. All patients suffered a first-ever stroke in the sub-acute stage defined as time since lesion onset from 1 month post-stroke.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Carrai, A. Grippo, A. Angelini, A. Vettori, T. Atzori, C. Falsini, M. Martini, A. Pizzi Source Type: research

Perception of lower extremity loading in stroke
We read with great interest the article entitled “Perception of lower extremity loads in stroke survivors” by Chu et al. (2014). There is a dearth of studies regarding perception of loading in stroke population. We applaud the authors for the contemporary thoughts on the method of measuring lower extremity dynamic load perception. We take this opportunity to share few scientific facts related to the scope of this article.
Source: Clinical Neurophysiology - October 25, 2014 Category: Neuroscience Authors: Senthil N.S. Kumar, Leonard H Joseph, Ahmad Pharmy Jalil Tags: Letter to the Editor Source Type: research

P11. Quality of Life after pediatric ischemic stroke: Five year follow-up of swiss children
Children after pediatric arterial ischemic stroke (AIS) are known to suffer from neurological and neuropsychological impairments but limited data is available concerning quality of life (QoL) outcome. The aim of this present study is to examine long-term effects on QoL in a population-based AIS sample from Switzerland.
Source: Clinical Neurophysiology - October 1, 2014 Category: Neuroscience Authors: S. Kornfeld, S. Winkelbeiner, M. Studer, E. Boltshauser, A. Capone Mori, A. Datta, J. Fluss, D. Mercati, A. Hackenberg, E. Keller, O. Maier, J.P. Marcoz, G.P. Ramelli, C. Poloni, R. Schmid, T. Schmitt-Mechelke, E Wehrli, T. Heinks, M. Steinlin Source Type: research

34. Modulation of cortical activity by botulinum toxin type a in patients with post-stroke arm spasticity
Conclusion: Study of 2 age-matched groups with mild and severe weakness demonstrated different effect of BoNT-lowered spasticity on motor system engagement. Group A during movement imagery at maximum BoNT effect manifested deactivation of visual and default mode system, perhaps a change from visual to kinesthetic imagery, with cerebellum participating. Group B during movement also manifested motor pattern normalization, especially reduced activation extent.Supported by IGA MZ CR NT13575.
Source: Clinical Neurophysiology - April 7, 2014 Category: Neuroscience Authors: P. Hluštík, T. Veverka, P. Hok, Z. Tüdös, P. Otruba, A. Krobot, P. Kaňovský Tags: Society Proceedings Source Type: research

8. Evolution and recovery of motor function post-stroke
Conclusion: Intracortical disinhibition occurs in both hemispheres immediately following acute stroke that likely represent functionally relevant changes supporting the recovery process in stroke. Whilst changes in the lesioned hemisphere persisted over the period of recovery in all patients, contralesional intracortical hyperexcitability persisted in patients with cortical strokes and those with more severe baseline functional impairment, suggesting that ongoing contralesional network recruitment may be necessary for those patients who have significant disruptions to the integrity of ipsilesional motor pathways. The study...
Source: Clinical Neurophysiology - March 3, 2014 Category: Neuroscience Authors: William Huynh, Steve Vucic, Arun V. Krishnan, Cindy S.-Y. Lin, Matthew C. Kiernan Tags: Society Proceedings Source Type: research

Reply to “The effects of functional electrical stimulation on upper extremity function and cortical plasticity in chronic stroke patients”
I appreciate the very important and developed suggestions by Dr. Cecatto for our article (). The proposals on the reasons why EMG-controlled FES (EMG–FES) could shift the brain hemispheric-dominant perfusion in our study provided our study further development and progress. The motor output and corresponding muscle and joint proprioceptive feedback may be tightly coupled and coordinated with movement by EMG–FES. As Dr. Cecatto proposed, these neural reorganisation mechanisms should be explored. The sensory components of large afferent fibre activation, proprioceptive input and increased cognitive sensory attention are a...
Source: Clinical Neurophysiology - February 10, 2014 Category: Neuroscience Authors: Yukihiro Hara Tags: Letters to the Editor Source Type: research

The effects of functional electrical stimulation on upper-extremity function and cortical plasticity in chronic stroke patients
I was pleased to read the study by . ‘The effects of electromyography-controlled functional electrical stimulation on upper extremity function and cortical perfusion in stroke patients’ published in the Clinical Neurophysiology journal.
Source: Clinical Neurophysiology - January 22, 2014 Category: Neuroscience Authors: Rebeca Boltes Cecatto Tags: Letters to the Editor Source Type: research

Priming sensorimotor cortex to enhance task-specific training after subcortical stroke
Conclusion: Primary motor cortex iTBS not only modulates M1 corticospinal excitability but also increases M1 receptiveness to sensory input.Significance: Priming with iTBSiM1 may enhance ipsilesional sensorimotor integration and facilitate better quality sensorimotor training after subcortical stroke.
Source: Clinical Neurophysiology - December 23, 2013 Category: Neuroscience Authors: Suzanne J. Ackerley, Cathy M. Stinear, P. Alan Barber, Winston D. Byblow Tags: Neural Plasticity, Functional Adaptation and Recovery Source Type: research

Corticomuscular coherence in acute and chronic stroke
Conclusions: The changes in CMC parameters in acute stroke could result from a temporary decrease in inhibition, which normalizes in the course of recovery. As all patients showed very good motor recovery, the modulation of CMC amplitude and frequency over time might thus reflect the process of motor recovery.Significance: We demonstrate for the first time the dynamical changes of corticomuscular interaction both at acute and chronic stage of stroke.
Source: Clinical Neurophysiology - December 6, 2013 Category: Neuroscience Authors: Katherina von Carlowitz-Ghori, Zubeyir Bayraktaroglu, Friederike U. Hohlefeld, Florian Losch, Gabriel Curio, Vadim V. Nikulin Tags: Movement, Motor Control and Movement Disorders Source Type: research

Temporal evolution of event-related desynchronization in acute stroke: A pilot study
Conclusion: The two evolutions presumably reflect the reorganization of brain networks and functional recovery after acute stroke. The significant increase of ipsilesional Sm in patients with a good recovery suggests an important role of this hemisphere during recovery.Significance: Improved understanding of ERD in acute stroke may assist in prognostication and rehabilitation.
Source: Clinical Neurophysiology - December 2, 2013 Category: Neuroscience Authors: Chayanin Tangwiriyasakul, Rens Verhagen, Wim L.C. Rutten, Michel J.A.M. van Putten Tags: Cerebral Function and its Development Source Type: research

Power spectral analysis of surface electromyography (EMG) at matched contraction levels of the first dorsal interosseous muscle in stroke survivors
Conclusions: There appears to be complex muscular and neural processes at work post stroke that may impact the surface EMG power spectrum. The majority of the tested stroke subjects had lower MPF in the paretic muscle than in the contralateral muscle at matched isometric contraction force. The reduced MPF of paretic muscles can be attributed to different factors such as increased motor unit synchronization, impairments in motor unit control properties, loss of large motor units, and atrophy of muscle fibers.Significance: Surface EMG power spectral analysis can serve as a useful tool to indicate complex neural and muscular ...
Source: Clinical Neurophysiology - November 22, 2013 Category: Neuroscience Authors: Xiaoyan Li, Henry Shin, Ping Zhou, Xun Niu, Jie Liu, William Zev Rymer Tags: Movement, Motor Control and Movement Disorders Source Type: research

146. Excitatory deep transcranial magnetic stimulation with H-coil over the right homologous Broca’s region improves naming in chronic post-stroke aphasia
This study aimed to compare the effect of excitatory, inhibitory and sham rTMS delivered with H-coil over the right inferior frontal gyrus (IFG) in chronic aphasic patients. Five right-handed post-stroke aphasic patients underwent a picture naming task before and immediately after each of three sessions of rTMS: excitatory (10Hz), inhibitory (1Hz) and sham rTMS, in random sequence and separated by at least 1 week. Only the excitatory 10Hz stimulation was associated with a significant improvement in naming performance, (p=0.043) and was significantly more effective than 1Hz rTMS (p=0.043). A single session of excitatory dee...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: R. Chieffo, F. Ferrari, P. Battista, E. Houdayer, A. Nuara, F. Alemanno, J. Abutalebi, A. Zangen, G. Comi, S.F. Cappa, L. Leocani Tags: Society Proceedings Source Type: research

120. Changing in effective cerebral connectivity during the acute phase of stroke: An EEG TMS study
This study demonstrated a clear modification in effective cortical connectivity during the acute phases of stroke. The EEG-TMS technique has proven useful in evaluating the modification of synaptic plasticity that occur in the acute phase of stroke, offering the opportunity to acquire information for prediction of the prognosis or new therapeutic approaches.
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: F. Giambattistelli, L. Tomasevic, F. Vernieri, F. Assenza, A. Pepe, F. Tecchio, P.M. Rossini Tags: Society Proceedings Source Type: research