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Source: Neurology

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Total 3153 results found since Jan 2013.

Leukocyte response in ischemic stroke is regulated by let7i microRNA (S51.005)
Conclusions:Let7i is decreased in circulating leukocytes of patients with acute ischemic stroke. Mechanisms by which let7i regulates inflammatory response post-stroke include targeting CD86, CXCL8 and HMGB1.Study Supported by: The American Heart Association (GCJ) and the National Institutes of Health (NS075035, NS079153, FRS).Disclosure: Dr. Jickling has nothing to disclose. Dr. Ander has nothing to disclose. Dr. Shroff has nothing to disclose. Dr. Stamova has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Sharp has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Jickling, G., Ander, B., Shroff, N., Stamova, B., Liu, D., Sharp, F. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Diagnostic value of prehospital ECG in acute stroke patients
Conclusions: In a selected cohort of patients with stroke, the in-field recordings of the ECG detected a relevant rate of cardiac arrhythmia. The results can add to the in-hospital evaluation and should be considered in prehospital care of acute stroke.
Source: Neurology - May 15, 2017 Category: Neurology Authors: Bobinger, T., Kallmünzer, B., Kopp, M., Kurka, N., Arnold, M., Heider, S., Schwab, S., Köhrmann, M. Tags: All Cerebrovascular disease/Stroke, Cardiac, Critical care ARTICLE Source Type: research

Risks and benefits of clopidogrel-aspirin in minor stroke or TIA: Time course analysis of CHANCE
Conclusions: Clopidogrel–aspirin treatment may have a benefit of reducing stroke risk outweighing the potential risk of increased bleeding especially within the first 2 weeks compared with aspirin alone in patients with minor stroke or TIA. Clinicaltrials.gov identifier: NCT00979589. Classification of evidence: This study provides Class II evidence that for patients with minor stroke or TIA, the reduction of stroke risk from clopidogrel plus aspirin within the first 2 weeks outweighs the risk of bleeding compared with aspirin alone.
Source: Neurology - May 15, 2017 Category: Neurology Authors: Pan, Y., Jing, J., Chen, W., Meng, X., Li, H., Zhao, X., Liu, L., Wang, D., Johnston, S. C., Wang, Y., Wang, Y., On behalf of the CHANCE investigators Tags: All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement) ARTICLE Source Type: research

Prospective association between {beta}2-microglobulin levels and ischemic stroke risk among women
Conclusion: High levels of B2M were associated with an increased risk of ischemic stroke among women.
Source: Neurology - June 5, 2017 Category: Neurology Authors: Rist, P. M., Jimenez, M. C., Rexrode, K. M. Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology ARTICLE Source Type: research

Structural MRI markers of brain aging early after ischemic stroke
Conclusions: Brain structure is likely to be compromised before ischemic stroke by vascular risk factors. Smaller hippocampal and total brain volumes and increased WMH load represent proxies for underlying vascular brain injury.
Source: Neurology - July 10, 2017 Category: Neurology Authors: Werden, E., Cumming, T., Li, Q., Bird, L., Veldsman, M., Pardoe, H. R., Jackson, G., Donnan, G. A., Brodtmann, A. Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Alzheimer's disease, Vascular dementia ARTICLE Source Type: research

Incidence and management of seizures after ischemic stroke: Systematic review and meta-analysis
Conclusions: The burden of stroke-related seizures and epilepsy due to ischemic stroke is substantial. Further studies are required to determine risk factors for epilepsy following ischemic stroke and optimal secondary prevention.
Source: Neurology - September 18, 2017 Category: Neurology Authors: Wang, J. Z., Vyas, M. V., Saposnik, G., Burneo, J. G. Tags: All Cerebrovascular disease/Stroke, Incidence studies, All Epilepsy/Seizures ARTICLE Source Type: research

Association between percent decline in serum total homocysteine and risk of first stroke
Conclusions: Percent lowering in tHcy was significantly associated with a reduction in first stroke risk in Chinese adults with hypertension, and if further confirmed, may serve as a useful indicator for folic acid treatment efficacy on stroke prevention. Clinicaltrials.gov identifier: NCT00794885.
Source: Neurology - November 13, 2017 Category: Neurology Authors: Huang, X., Li, Y., Li, P., Li, J., Bao, H., Zhang, Y., Wang, B., Sun, N., Wang, J., He, M., Yin, D., Tang, G., Chen, Y., Cui, Y., Huang, Y., Hou, F. F., Qin, X., Huo, Y., Cheng, X. Tags: Stroke prevention, All Clinical trials ARTICLE Source Type: research

MRI findings and stroke risk in TIA patients with different symptom durations
Conclusion: Stroke risk was higher after tissue-positive events than tissue-negative ones in TIA patients with different symptom duration.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Al-Khaled, M., Eggers, J. Tags: MRI, DWI, Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research

Risk of incident stroke in patients with Alzheimer disease or vascular dementia
Conclusions: Patients with VD, but not AD, have a markedly higher risk of developing an ischemic stroke than those without dementia. In patients with AD, but not VD, use of atypical antipsychotic drugs was associated with an increased risk of TIA.
Source: Neurology - September 2, 2013 Category: Neurology Authors: Imfeld, P., Bodmer, M., Schuerch, M., Jick, S. S., Meier, C. R. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Vascular dementia, Case control studies, Incidence studies ARTICLE Source Type: research

Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
Conclusion: HZ is an independent risk factor for vascular disease in the UK population, particularly for stroke, TIA, and MI in subjects affected before the age of 40 years. In older subjects, better ascertainment of vascular risk factors and earlier intervention may explain the reduction in risk of stroke after the occurrence of HZ.
Source: Neurology - January 20, 2014 Category: Neurology Authors: Breuer, J., Pacou, M., Gauthier, A., Brown, M. M. Tags: Stroke in young adults, Viral infections, All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Sex differences in quality of life after ischemic stroke
Conclusion: Women have worse QOL than men up to 12 months after stroke, even after adjusting for important sociodemographic variables, stroke severity, and disability.
Source: Neurology - March 17, 2014 Category: Neurology Authors: Bushnell, C. D., Reeves, M. J., Zhao, X., Pan, W., Prvu-Bettger, J., Zimmer, L., Olson, D., Peterson, E. Tags: Quality of life, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Failed Bedside Dysphagia Screen Predicts Pneumonia Treatment in Acute Stroke: A Resident Quality Initiative Project in a JC-Certified Primary Stroke Center (P3.124)
CONCLUSION: Bedside dysphagia screen effectively identifies patients at increased risk of pneumonia. Patients who fail dysphagia screen have increased risk of being treated for pneumonia during their acute stroke hospitalization.Study supported by: NoneDisclosure: Dr. Babi has nothing to disclose. Dr. Gorman has received personal compensation for activities with Boston Scientific Corp. Dr. Commichau has nothing to disclose. Dr. Kenney has nothing to disclose. Dr. Boyle has nothing to disclose. Dr. Comeau has nothing to disclose. Dr. Hulsey has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Babi, M.-A., Gorman, M., Commichau, C., Kenney, S., Boyle, L., Comeau, M., Hulsey, S. Tags: Cerebrovascular Disease and Interventional Neurology: Primary and Comprehensive Stroke Centers Source Type: research

The Presence of Neurology Impacting Door to Needle Time in Acute Stroke (P7.131)
CONCLUSIONS:Overall, it appears that the stroke protocol process runs more effectively and rapidly with a neurologist present at the bedside. Possible solutions to improve door to needle time include having a neurologist in house 24-7 or a resident driven protocol.Study Supported by:Disclosure: Dr. Kurowski has nothing to disclose. Dr. Soto has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Kurowski, D., Soto, O. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Awareness of Stroke and Knowledge of its Warning Signs and Risk Factors in a Developing Country (P7.133)
CONCLUSIONS: The study clearly revealed lack of public’s knowledge about stroke, its warning symptoms and risk factors in the community investigated. Improvement in stroke awareness level can be achieved by health education utilizing the media tools preferred by the targeted population. Study Supported by:Disclosure: Dr. Sokrab has nothing to disclose. Dr. Sokrab has nothing to disclose. Dr. Hassan has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Sokrab, O., Sokrab, A., Hassan, E. F. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Impact of Stroke Location on Stroke Outcome (P7.147)
CONCLUSIONS:Selective involvement of cortex or subcortical areas of brain due to ischemic stroke did not correlate with functional outcome at 3 months following thrombolysis. Patients with diabetes mellitus were more likely to have cortical strokes than subcortical strokes.Study Supported by:NoneDisclosure: Dr. Hinduja has nothing to disclose. Dr. Limaye has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Mahuwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hinduja, A., Limaye, K., Patel, A., Mahuwala, Z. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research