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Source: Neurology

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Total 3153 results found since Jan 2013.

Prehospital thrombolysis in acute stroke: Results of the PHANTOM-S pilot study
Conclusions: The data suggest that prehospital stroke care in STEMO is feasible. No safety concerns have been raised so far. This new approach using prehospital tPA may be effective in reducing call-to-needle times, but this is currently being scrutinized in a prospective controlled study.
Source: Neurology - January 7, 2013 Category: Neurology Authors: Weber, J. E., Ebinger, M., Rozanski, M., Waldschmidt, C., Wendt, M., Winter, B., Kellner, P., Baumann, A., Fiebach, J. B., Villringer, K., Kaczmarek, S., Endres, M., Audebert, H. J., for the STEMO-Consortium Tags: CT, All Cerebrovascular disease/Stroke, Critical care, Patient safety ARTICLE Source Type: research

Outcomes of Thrombolytic Treatment for Acute Ischemic Stroke in Dialysis Dependant Patients in the United States (S02.003)
CONCLUSIONS: The three fold higher odds of in-hospital mortality associated with administration of IV thrombolytics in dialysis dependant patients who present with acute ischemic stroke warrants a careful assessment of risk benefit ratio in this population.Disclosure: Dr. Adil has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Irfan has nothing to disclose. Dr. Chaudhry has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Tariq, N., Adil, M., Irfan, M., Chaudhry, S., Qureshi, A. Tags: S02 Acute Stroke Therapy Source Type: research

The search for paroxysmal atrial fibrillation in cryptogenic stroke: Leave no stone unturned
Atrial fibrillation (AF), a well-established cause of ischemic stroke, is found in up to 25% of first strokes.1,2 Most patients with stroke from AF will benefit from anticoagulation for secondary stroke prevention, so finding AF as a cause of ischemic stroke is critical. Many patients with AF have paroxysmal AF (PAF), in which periods of normal sinus rhythm alternate with sometimes brief episodes of AF. Conventional monitoring for AF in the hospital or for a small number of days as an outpatient may therefore miss the diagnosis of PAF. Although most of the data to support anticoagulation for stroke patients with AF come fr...
Source: Neurology - April 22, 2013 Category: Neurology Authors: Flint, A. C., Tayal, A. H. Tags: All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Stroke prevention in the Stroke Belt: Is the adolescence period the clue?
Early prevention of diseases is crucial for public health, especially for stroke and heart disease, the leading causes of morbidity and mortality in the United States. Global geographic disparities in stroke incidence and mortality are substantial. In the United States, residents of the southeastern states endure higher stroke mortality than other regions.1 Many theories have attempted to explain the excess burden of stroke in this Stroke Belt (SB) without convincing explanations.
Source: Neurology - April 29, 2013 Category: Neurology Authors: Castilla-Guerra, L., Mokdad, A. H. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Report of stroke-like symptoms predicts incident cognitive impairment in a stroke-free cohort
Conclusions: Report of SS/TIA showed a strong association with incident cognitive impairment and supports the use of the Questionnaire for Verifying Stroke-free Status as a quick, low-cost instrument to screen for people at increased risk of cognitive decline.
Source: Neurology - July 8, 2013 Category: Neurology Authors: Kelley, B. J., McClure, L. A., Letter, A. J., Wadley, V. G., Unverzagt, F. W., Kissela, B. M., Kleindorfer, D., Howard, G. Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Vascular dementia, All epidemiology ARTICLE Source Type: research

Prehospital stroke care: New prospects for treatment and clinical research
Brain cells die rapidly after stroke and any effective treatment must start as early as possible. In clinical routine, the tight time–outcome relationship continues to be the major limitation of therapeutic approaches: thrombolysis rates remain low across many countries, with most patients being treated at the late end of the therapeutic window. In addition, there is no neuroprotective therapy available, but some maintain that this concept may be valid if administered very early after stroke. Recent innovations have opened new perspectives for stroke diagnosis and treatment before the patient arrives at the hospital....
Source: Neurology - July 29, 2013 Category: Neurology Authors: Audebert, H. J., Saver, J. L., Starkman, S., Lees, K. R., Endres, M. Tags: All Clinical trials, All Cerebrovascular disease/Stroke VIEWS & amp;amp; REVIEWS Source Type: research

Role of trauma and infection in childhood hemorrhagic stroke due to vascular lesions
Conclusions: Our observed association between trauma and hemorrhagic stroke with a vascular lesion may be explained by traumatic pseudoaneurysms. Neither recent head or neck trauma nor infection appeared to be a "trigger" for pediatric hemorrhagic stroke due to underlying vascular malformations.
Source: Neurology - August 5, 2013 Category: Neurology Authors: Singhal, N. S., Hills, N. K., Sidney, S., Fullerton, H. J. Tags: Childhood stroke, All Pediatric, Arteriovenous malformation, Intracerebral hemorrhage ARTICLE Source Type: research

Recognition and management of stroke in young adults and adolescents
Approximately 15% of all ischemic strokes (IS) occur in young adults and adolescents. To date, only limited prior public health and research efforts have specifically addressed stroke in the young. Early diagnosis remains challenging because of the lack of awareness and the relative infrequency of stroke compared with stroke mimics. Moreover, the causes of IS in the young are heterogeneous and can be relatively uncommon, resulting in uncertainties about diagnostic evaluation and cause-specific management. Emerging data have raised public health concerns about the increasing prevalence of traditional vascular risk factors i...
Source: Neurology - September 16, 2013 Category: Neurology Authors: Singhal, A. B., Biller, J., Elkind, M. S., Fullerton, H. J., Jauch, E. C., Kittner, S. J., Levine, D. A., Levine, S. R. Tags: Childhood stroke, Stroke in young adults, All Cerebrovascular disease/Stroke, Carotid artery dissection, Infarction VIEWS & amp;amp; REVIEWS Source Type: research

A decade of racial and ethnic stroke disparities in the United States
Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Stroke incidence and prevalence is not uniform. It occurs more frequently in some geographical areas of the United States and the rates are higher in minority groups.1,2 Some proposed causes for these disparities include increased rate of vascular risk factors that disproportionally affect some minority groups, differential effect of hypertension on stroke risk across racial groups, lack of access to health care and other social determinants of health, suboptimal control of risk factors, and although lacking subs...
Source: Neurology - March 24, 2014 Category: Neurology Authors: Gutierrez, J., Williams, O. A. Tags: Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Prevalence studies, Risk factors in epidemiology GLOBAL PERSPECTIVES Source Type: research

Prehypertension and the risk of stroke: A meta-analysis
Conclusions: After adjusting for multiple cardiovascular risk factors, prehypertension is associated with stroke morbidity. Although the increased risk is largely driven by high-range prehypertension, the risk is also increased in people with low-range prehypertension.
Source: Neurology - March 31, 2014 Category: Neurology Authors: Huang, Y., Cai, X., Li, Y., Su, L., Mai, W., Wang, S., Hu, Y., Wu, Y., Xu, D. Tags: All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Cryptogenic Stroke with No Cause Demonstrates the Outcome Prediction Utility of TOAST Classifications in a Large Stroke Patient Sample (P1.118)
Conclusion: Even after controlling for higher tPA treatment rates, patients with cryptogenic no cause by TOAST classification had better outcomes than other TOAST groups. Our results suggest that determining stroke etiology with the TOAST classification can be a clinical useful tool for risk stratification for stroke patients even with difficult diagnosis groups like cryptogenic no cause.Disclosure: Dr. Scullen has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. George has received research support from Tulane University School of Medicine. Dr. Siegler has nothing to disclose. Dr. Schwickrath has nothing...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Scullen, T., Monlezun, D., George, A., Siegler, J., Schwickrath, M., El Khoury, R., Martin-Schild, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Automated Datamining To Create Stroke Database And Concurrent 'Managed Alerts' For Comprehensive Stroke Center Metrics (P3.119)
Conclusions: The study shows the automated method better than the manual method when electronic data can be harnessed, as it creates a more accurate, efficient, and effective process with continuous improvement.Study supported by: Lytics-ML28111 study (Genentech)Disclosure: Dr. Madhavan has received personal compensation for activities with Process Proxy Corporation. Dr. Madhavan has received research support from Genentech, Inc. Dr. Abhishek has nothing to disclose. Dr. Parliament has nothing to disclose. Dr. Dietrich has nothing to disclose. Dr. Seraji-Bozorgzad has nothing to disclose. Dr. Bhattacharya has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Madhavan, R., Abhishek, F., Parliament, C., Dietrich, M., Seraji-Bozorgzad, N., Bhattacharya, P. Tags: Cerebrovascular Disease and Interventional Neurology: Primary and Comprehensive Stroke Centers Source Type: research

Perception Of Stroke Symptoms And Utilization Of Emergency Medical Systems In Argentina (P7.132)
CONCLUSIONS:These results suggest a low level of stroke symptoms awareness in our country even in a population of middle/high socioeconomic level. The role and procedures of EMS in Argentina should be revised as early arrival and treatment appear to be associated with no utilization of them.Study Supported by:Disclosure: Dr. Hawkes has nothing to disclose. Dr. Calandri has nothing to disclose. Dr. Farez has received personal compensation for activities with Merck Serono. Dr. Farez has received research support from Novartis. Dr. Arena has nothing to disclose. Dr. Pujol Lereis has nothing to disclose. Dr. Ameriso has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hawkes, M., Calandri, I., Farez, M., Arena, J., Pujol Lereis, V., Ameriso, S. Tags: Cerebrovascular Disease and Interventional Neurology: Barriers and Opportunities in Acute Stroke Treatment Source Type: research

Diastolic Function of Heart and Outcomes After Ischemic Stroke (P7.151)
CONCLUSIONS: Because E/E’ is best correlated with invasively-assessed diastolic function, our results suggested that diastolic dysfunction may hinder a functional regain following ischemic stroke.Study Supported by:Disclosure: Dr. Hee Seung has nothing to disclose. Dr. Wi-Sun has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hee Seung, A., Wi-Sun, R. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Cryptogenic Stroke with No Cause Demonstrates the Outcome Prediction Utility of TOAST Classifications in a Large Stroke Patient Sample (I2-1.005)
Conclusion: Even after controlling for higher tPA treatment rates, patients with cryptogenic no cause by TOAST classification had better outcomes than other TOAST groups. Our results suggest that determining stroke etiology with the TOAST classification can be a clinical useful tool for risk stratification for stroke patients even with difficult diagnosis groups like cryptogenic no cause.Disclosure: Dr. Scullen has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. George has received research support from Tulane University School of Medicine. Dr. Siegler has nothing to disclose. Dr. Schwickrath has nothing...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Scullen, T., Monlezun, D., George, A., Siegler, J., Schwickrath, M., El Khoury, R., Martin-Schild, S. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research