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Source: Journal of Clinical Neuroscience
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Total 328 results found since Jan 2013.
High resolution vessel wall MR imaging in prestenotic intracranial atherosclerotic disease
We present a case of intracranial hemorrhage presumably due to intracranial atherosclerotic disease (ICAD) identified by VWI and silent on lumen-based imaging modalities. A 66-year-old female presented with sudden onset headache and dysarthria. A head CT showed intracranial hemorrhage centered in the right basal ganglia. Further imaging by CT angiography, MR angiography and a conventional catheter angiogram were negative. MRI of the brain, including VWI, showed abnormal enhancement in the right middle cerebral artery vessel wall, suggesting intracranial atherosclerotic changes in a prestenotic vessel. As a potential noninv...
Source: Journal of Clinical Neuroscience - January 23, 2019 Category: Neuroscience Source Type: research
Correlation between pre-admission blood pressure and outcome in a large telestroke cohort
ConclusionsThis study displays better clinical outcomes at latest follow-up when compared to current international TS studies. SBP during transportation to the hub hospital did not prove to be a useful prognostic metric. However, future studies should address the limitations of this study to confirm these findings.
Source: Journal of Clinical Neuroscience - January 17, 2019 Category: Neuroscience Source Type: research
Fluid and energy intake in stroke patients during acute hospitalization in a stroke unit
Publication date: Available online 14 January 2019Source: Journal of Clinical NeuroscienceAuthor(s): Alex Buoite Stella, Marina Gaio, Giovanni Furlanis, Pauline Douglas, Marcello Naccarato, Paolo ManganottiAbstractProper hydration and nutrition have been found to be contributing factors to a better recovery in patients after stroke. A better knowledge of factors influencing fluid and energy intake may contribute to a better care of the acute stroke patient. Aim of this study was to describe hydration status, fluid intake, and energy intake of stroke patients during acute hospitalization in a stroke unit. A retrospective de...
Source: Journal of Clinical Neuroscience - January 15, 2019 Category: Neuroscience Source Type: research
Implementation of multiphase computed tomography angiography in management of patients with acute ischemic stroke in clinical practice
Publication date: Available online 19 December 2018Source: Journal of Clinical NeuroscienceAuthor(s): Nattaphol Uransilp, Pornpatr A. Dharmasaroja, Arvemas Watcharakorn, Sombat MuengtaweepongsaAbstractMultiphase computed tomography angiography (CTA) provides information on the status of major cranial arteries and extent of brain collateralization. The purpose of the study was to determine whether implementation of multiphase CTA in routine clinical practice was feasible, safe and useful. Patients with acute ischemic stroke (NIHSS ≥ 6) were included. Multiphase CTA was performed. Duration of performing multiphase CTA,...
Source: Journal of Clinical Neuroscience - December 20, 2018 Category: Neuroscience Source Type: research
Abnormal red blood cell indices increase the risk of arterial ischemic stroke in children
Publication date: Available online 19 December 2018Source: Journal of Clinical NeuroscienceAuthor(s): Chaiyos Khongkhatithum, Praguywan Kadegasem, Werasak Sasanakul, Lunliya Thampratankul, Ampaiwan Chuansumrit, Nongnuch SirachainanAbstractA high red cell distribution width (RDW) and low hemoglobin level increase the risk of arterial ischemic stroke (AIS), mostly in adults. The mechanisms related to AIS remain unknown. A total of 233 subjects (90 patients and 143 healthy controls [HC]) were enrolled. The mean(SD) age in patients and HC was 9.5(3.8) and 11.4(1.8) years, respectively. We found increased odds ratios (ORs) for ...
Source: Journal of Clinical Neuroscience - December 20, 2018 Category: Neuroscience Source Type: research
Blood microRNA-93 as an indicator for diagnosis and prediction of functional recovery of acute stroke patients
Publication date: Available online 19 December 2018Source: Journal of Clinical NeuroscienceAuthor(s): Qingfeng Ma, Guangwen Li, Zhen Tao, Jue Wang, Rongliang Wang, Ping Liu, Yumin Luo, Haiping ZhaoAbstractThe present study evaluated the diagnostic and predictive potential of microRNA-93 in acute ischemic stroke (AIS) patients within 6 h of stroke onset and its regulation on microglial inflammation in vitro. Our results showed that the miR-93 levels in plasma and neutrophil detected by real-time PCR were evidently reduced in AIS patients, and Pearson's correlation analysis showed that miR-93 levels in plasma and neutrophi...
Source: Journal of Clinical Neuroscience - December 20, 2018 Category: Neuroscience Source Type: research
Vertebrobasilar dolichoectasia presenting simultaneously with ischemic and hemorrhagic strokes
ConclusionThe perforating vessels branching off of the pathologic VBDE may result in both ischemia and hemorrhage. This is the first known case, to our knowledge, in which hemorrhage and cerebral ischemia occurred simultaneously.
Source: Journal of Clinical Neuroscience - November 12, 2018 Category: Neuroscience Source Type: research
Risk factors for ischemic stroke post bone fracture
Publication date: Available online 7 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Qi An, Zhe Chen, Kang Huo, Hua Su, Qiu-Min QuAbstractStroke is one of the most devastating complications after bone fracture. However, due to the rarity of the complication, the risk factor for post fracture stroke remains unknown. We retrospectively reviewed 2914 fractured adults referred to the first affiliated hospital of Xi’an Jiaotong University, a regional referral center of China, from January 2008 to May 2013. As a result, among the 2914 patients, 13 of them had newly onset stroke within a median of 4 days after...
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
Thrombectomy in stroke of unknown onset, wake up stroke and late presentations: Australian experience from 2 comprehensive stroke centres
This study shows good ‘real world’ outcomes, comparable to published RCTs, in patients with unknown-onset, or late presentation, stroke treated with EVT more than 6 h from stroke onset.
Source: Journal of Clinical Neuroscience - November 8, 2018 Category: Neuroscience Source Type: research
“In Safe Hands” – A costly integrated care program with limited benefits in stroke unit care
Publication date: Available online 6 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Sheila Jala, Sarah Giaccari, Melissa Passer, Carin Bertmar, Susan Day, Dayna Griffith, Martin KrauseAbstractGiven reported favourable outcomes of accountable care unit models of health care delivery (Taylor et al., 2017; Stein et al., 2015; Kara et al., 2015), the Clinical Excellence Commission of NSW has embraced “In Safe Hands” (ISH) to enhance coordination of care. ISH embraces the structured interdisciplinary bedside round (SIBR) component, for which reported outcomes include reduced length of stay (Taylor et al., 2...
Source: Journal of Clinical Neuroscience - November 6, 2018 Category: Neuroscience Source Type: research
Efficacy and safety of drug-eluting stent for the intracranial atherosclerotic disease: A systematic review and meta-analysis
Publication date: Available online 3 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Gengfan Ye, Xiaoliang Yin, Ximeng Yang, Junjie Wang, Peng Qi, Jun Lu, Lijun Wang, Daming WangAbstractDrug-eluting stent (DES) is a potential endovascular treatment for patients with symptomatic intracranial atherosclerotic disease (sICAD). However, evidence regarding the treatment of ICAD with DES is lacking. We systematically searched Pubmed, Embase, Cochrane database (before 2017-12-21) for literature reporting the application of DES in the treatment of sICAD. The main outcomes were as follows: the incidence of any stroke...
Source: Journal of Clinical Neuroscience - November 4, 2018 Category: Neuroscience Source Type: research
Iron nanoparticle contrast enhanced microwave imaging for emergent stroke: A pilot study
Publication date: Available online 1 November 2018Source: Journal of Clinical NeuroscienceAuthor(s): Joseph S. Hudson, Timothy K. Chung, Benjamin S. Prout, Yasunori Nagahama, Madhavan L. Raghavan, David M. HasanAbstractEmergent stroke is mostly evaluated using hospital based imaging. Quick imaging allows for rapid administration of IV thrombolysis and outcome improvement. Microwave imaging (MI) is an emerging portable imaging modality. Iron oxide nanoparticles are known to interact with microwave frequency electromagnetic radiation. In this manuscript, we provide proof of concept for a novel iron oxide nanoparticle enhance...
Source: Journal of Clinical Neuroscience - November 2, 2018 Category: Neuroscience Source Type: research
A swine model of intracellular cerebral edema – Cerebral physiology and intracranial compliance
We describe a swine model of water intoxication and its cerebral histological and physiological sequela. We studied female swine weighing 35–45 kg. Four serum sodium intervals were designated: baseline, mild, moderate, and severe hyponatremia attained by infusing hypotonic saline. Intracranial fluid injections were performed to assess intracranial compliance. At baseline and following water intoxication wedge biopsy was obtained for pathological examination and electron microscopy. We studied 8 swine and found an increase in ICP that was strongly related to the decrease in serum sodium level. Mean ICP rose from a basel...
Source: Journal of Clinical Neuroscience - October 26, 2018 Category: Neuroscience Source Type: research
Post-thrombolysis rupture of small lenticulostriate aneurysms: A report of 2 consecutive cases
This report suggests that LSA aneurysms, regardless of size, be considered separately from other conventional aneurysms as “high-risk” lesions and a contraindication to thrombolysis.
Source: Journal of Clinical Neuroscience - October 25, 2018 Category: Neuroscience Source Type: research
2016–2017 clinical trials in cerebrovascular neurosurgery
Publication date: Available online 24 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Wendy Huang, Rose DuAbstractSeveral clinical trials in cerebrovascular neurosurgery were published during 2016–2017. The Collaborative Unruptured Endovascular versus Surgery Trial (CURES) found no difference in outcome between clipping versus coiling of unruptured aneurysms after one year. The Flow Diversion in the Treatment of Intracranial Aneurysm Trial (FIAT) was terminated due to safety concerns. Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity after Subarachnoid Hemorrhage Trial (NEWTON) and othe...
Source: Journal of Clinical Neuroscience - October 25, 2018 Category: Neuroscience Source Type: research
