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Source: Journal of Clinical Neuroscience
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Total 328 results found since Jan 2013.
Treatment of patients with mild acute ischemic stroke and associated large vessel occlusion
Publication date: Available online 3 April 2016 Source:Journal of Clinical Neuroscience Author(s): Russell Cerejo, Esteban Cheng-Ching, Ferdinand Hui, M. Shazam Hussain, Ken Uchino, Jennifer Bullen, Gabor Toth Several recent studies have shown that patients presenting with mild acute ischemic stroke (mAIS) symptoms may have an unfavorable natural history. The presence of associated large vessel occlusion (LVO) may lead to even worse outcomes, but most mAIS patients are still excluded from acute stroke treatment (AST). A retrospective review of patients with acute ischemic stroke presenting to our institution betwe...
Source: Journal of Clinical Neuroscience - April 3, 2016 Category: Neuroscience Source Type: research
Endovascular therapy including thrombectomy for acute ischemic stroke: A systematic review and meta-analysis with trial sequential analysis
Publication date: Available online 2 March 2016 Source:Journal of Clinical Neuroscience Author(s): Kevin Phan, Dong Fang Zhao, Steven Phan, Ya Ruth Huo, Ralph J. Mobbs, Prashanth J. Rao, Alex M. Mortimer One of the primary strategies for the management of acute ischemic stroke is intravenous (IV) thrombolysis with tissue plasminogen activator (t-PA). Over the past decade, endovascular therapies such as the use of stent retrievers to perform mechanical thrombectomy have been found to improve functional outcomes compared to t-PA alone. We aimed to reassess the functional outcomes and complications of IV thrombolysis...
Source: Journal of Clinical Neuroscience - March 3, 2016 Category: Neuroscience Source Type: research
Microvascular decompression for elderly patients with trigeminal neuralgia
Publication date: Available online 2 March 2016 Source:Journal of Clinical Neuroscience Author(s): Kevin Phan, Prashanth J. Rao, Mark Dexter Microvascular decompression (MVD) has been demonstrated to be an excellent surgical treatment approach in younger patients with trigeminal neuralgia (TN). However, it is not clear whether there are additional morbidity and mortality risks for MVD in the elderly population. We performed a systematic literature review using six electronic databases for studies that compared outcomes for MVD for TN in elderly (cut-off ⩾60, 65, 70years) versus younger populations. Outcomes examined...
Source: Journal of Clinical Neuroscience - March 2, 2016 Category: Neuroscience Source Type: research
Airplane stroke syndrome
We describe the patient, stroke, and flight characteristics. Over the study period, 131 million passengers arrived at Melbourne airport. Our centre admitted 5727 stroke patients, of whom 42 (0.73%) had flight-related strokes. Flight-related stroke patients were younger (median age 65 versus 73, p<0.001), had similar stroke severity, and received intravenous thrombolysis more often than non-flight-related stroke patients. Seven patients had flight-related intracerebral haemorrhage. The aetiology of the ischaemic strokes was cardioembolic in 14/35 (40%), including seven patients with confirmed PFO, one with atrial sep...
Source: Journal of Clinical Neuroscience - February 20, 2016 Category: Neuroscience Source Type: research
Intravenous thrombolysis, mechanical embolectomy, and intracranial stenting for hyperacute ischemic stroke in a patient with moyamoya disease
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Debora S. Argetsinger, Jeffrey W. Miller, Jeffrey J. Fletcher The Japanese translation of moyamoya means “puff of smoke” and refers to the angiographic appearance of dilated collateral vessels seen during chronic progressive narrowing of the intracranial supraclinoid portions of the internal carotid arteries. Despite cerebral ischemia being the most common presenting symptom, 20% to 40% of adults suffer a hemorrhagic stroke. Due to the lack of evidence and histopathologic findings, intravenous and endovascular re...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research
Isolated asymptomatic pulmonary arteriovenous malformation presenting with ischaemic stroke
Publication date: Available online 17 February 2016 Source:Journal of Clinical Neuroscience Author(s): Kelly L. Bertram, Anoop Madan, Judith Frayne Young onset stroke is uncommon, and may be due to conditions other than traditional vascular risk factors. A 42-year-old woman with an ischaemic stroke was found to have left atrial bubble study positivity on transthoracic echocardiogram (TTE) suggestive of patent foramen ovale, however she also had low peripheral oxygen saturation. Investigation revealed an isolated pulmonary arteriovenous malformation (PAVM), visible on admission chest radiograph. This can cause embolic ...
Source: Journal of Clinical Neuroscience - February 18, 2016 Category: Neuroscience Source Type: research
Diagnosing acute lacunar infarction using CT perfusion
Publication date: Available online 15 February 2016 Source:Journal of Clinical Neuroscience Author(s): Wenjie Cao, Nawaf Yassi, Gagan Sharma, Bernard Yan, Patricia M. Desmond, Stephen M. Davis, Bruce C.V. Campbell The value of CT perfusion (CTP) in detecting acute lacunar infarcts (LACI) has not been well established. We tested the sensitivity of CTP for LACI. CTP maps of consecutive stroke patients from 2009–2013 were examined. MRI diffusion imaging was used to identify those with LACI. Two stroke neurologists independently evaluated the CTP maps for evidence of a perfusion lesion in a deep perforating artery t...
Source: Journal of Clinical Neuroscience - February 17, 2016 Category: Neuroscience Source Type: research
Recurrent episodes of stroke in a young adult: question
Publication date: February 2016 Source:Journal of Clinical Neuroscience, Volume 24 Author(s): Ramachandiran Nandhagopal, Fathiya Al-Murshedi, Stefan Weiss, Douglas Friday
Source: Journal of Clinical Neuroscience - January 16, 2016 Category: Neuroscience Source Type: research
Recurrent episodes of stroke in a young adult: answer
Publication date: February 2016 Source:Journal of Clinical Neuroscience, Volume 24 Author(s): Ramachandiran Nandhagopal, Fathiya Al-Murshedi, Stefan Weiss, Douglas Friday
Source: Journal of Clinical Neuroscience - January 16, 2016 Category: Neuroscience Source Type: research
Direct admission to stroke centers reduces treatment delay and improves clinical outcome after intravenous thrombolysis
Publication date: Available online 9 January 2016 Source:Journal of Clinical Neuroscience Author(s): Dae-Hyun Kim, Hee-Joon Bae, Moon-Ku Han, Beom Joon Kim, Sang-Soon Park, Tai Hwan Park, Kyung Bok Lee, Kyusik Kang, Jong-Moo Park, Youngchai Ko, Soo Joo Lee, Jay Chol Choi, Joon-Tae Kim, Ki-Hyun Cho, Keun-Sik Hong, Yong-Jin Cho, Dong-Eog Kim, Jun Lee, Juneyoung Lee, Mi Sun Oh, Kyung-Ho Yu, Byung-Chul Lee, Hyun-Wook Nah, Jae-Kwan Cha We aimed to examine whether direct access to hospitals offering intravenous thrombolysis is associated with functional outcomes in patients with acute ischemic stroke tr...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Ten year clinical experience with stroke and cerebral vasculitis
Publication date: Available online 8 January 2016 Source:Journal of Clinical Neuroscience Author(s): Peter A. Kempster, Catriona A. McLean, Thanh G. Phan Angiitis of the central nervous system (CNS) is difficult to diagnose but potentially fatal. When stroke occurs in a younger individual or is associated with multiple infarcts on imaging, clinicians must decide how far to pursue a possible diagnosis of vasculitis. The aim of this study is to establish the prevalence of primary and secondary cerebral angiitis among patients presenting with stroke. Hospital attendances over a 10year period were surveyed by searching fo...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Management of moyamoya syndrome in patients with Noonan syndrome
We report four cases of Noonan syndrome patients presenting with headaches and/or sensorimotor strokes in childhood that caused unilateral sensorimotor impairment. Cerebral angiography and MRI revealed bilateral moyamoya syndrome. All patients underwent successful bilateral extracranial-to-intracranial revascularization. The first patient was a 10-year-old girl who presented following a hemorrhagic stroke and recovered well after indirect bypass. The second patient was an adult with a history of childhood stroke whose symptoms progressed in adulthood. She underwent a direct bypass and improved, but continued to experience ...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Tibial somatosensory evoked potential can prognosticate for ambulatory function in subacute hemiplegic stroke
Publication date: Available online 5 January 2016 Source:Journal of Clinical Neuroscience Author(s): Pyoungsik Hwang, Min Kyun Sohn, Cuk-Seong Kim, Sungju Jee Early prediction of expected recovery in stroke can help in planning appropriate medical and rehabilitation interventions. Recovery of ambulation is one of the essential endpoints in stroke rehabilitation. However, the correlation of somatosensory evoked potentials (SSEP) with clinical parameters and their predictive significance are not clearly defined. We aimed to examine the association between tibial nerve SSEP and ambulatory outcomes in subacute hemiplegic...
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Flexor and extensor muscle tone evaluated using the quantitative pendulum test in stroke and parkinsonian patients
In conclusion, the hypertonia of parkinsonian and stroke patients could not be differentiated by the modified pendulum test; the elbow extensors showed a higher muscle tone in both control and patient groups; and hypertonia of both parkinsonian and stroke patients is velocity dependent.
Source: Journal of Clinical Neuroscience - January 11, 2016 Category: Neuroscience Source Type: research
Rapid access point of care clinic for transient ischemic attacks and minor strokes
We present 24months of prospective data from a new model of care for transient ischemic attacks (TIA) and minor stroke, established at the Royal North Shore Hospital, a tertiary teaching hospital in Sydney, Australia. Prior to 2011, approximately 200 patients were admitted to our emergency department (ED) annually, following presentation with a suspected TIA. These patients had an average length of stay of 5.3days. Following the establishment of a twice weekly multidisciplinary, one stop, stroke prevention and hospital avoidance clinic, all patients with suspected TIA were investigated and treated as outpatients. There was...
Source: Journal of Clinical Neuroscience - December 18, 2015 Category: Neuroscience Source Type: research
