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Source: Journal of Clinical Neuroscience
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Total 328 results found since Jan 2013.
Emergency medical services for acute ischemic stroke: Hub-and-spoke model versus exclusive care in comprehensive centers
ConclusionsUsing a comprehensive all-payer cohort of acute ischemic stroke patients in New York State we demonstrated that patients treated in a hub-and-spoke model were not associated with worse outcomes than patients receiving care exclusively in comprehensive institutions. This needs to be taken into consideration when considering acute emergency services in this setting.
Source: Journal of Clinical Neuroscience - October 20, 2018 Category: Neuroscience Source Type: research
Impact of risk factors for recurrence after the first ischemic stroke in adults: A systematic review and meta-analysis
Publication date: Available online 16 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Shengbang Zheng, Baodong YaoAbstractRisk factors for first-ever stroke have been studied extensively, while those for recurrent stroke are not accurately understood. To provide the adequate secondary prevention for the patients, it is necessary to reveal the risk factors that dominate recurrent stroke. Multiple databases were adopted to search for the relevant studies and full-text articles involving in the risk factors for stroke recurrence were reviewed. Meta-analyses were performed with Review Manager 5.0 to estimate the...
Source: Journal of Clinical Neuroscience - October 17, 2018 Category: Neuroscience Source Type: research
The cooking therapy for cognitive rehabilitation of cerebellar damage: A case report and a review of the literature
ConclusionThe comparison of our data with those reported in previous studies confirmed the Schmahmann’s hypothesis on the effectiveness of neurorehabilitation approaches in cerebellar patients acting as external timekeeping of conscious thoughts.Graphical abstractThe cooking therapy framework for the rehabilitation of the cerebellar patients. The patient underwent 18 levels divided into three courses (starter, pasta, and main) X 2 food meals (meat-fish) X 3 levels of difficulty (1°–2°–3° meal). Tomato sauce is the main food, which is prepared each time for every single meal. All cooking levels started with the pre...
Source: Journal of Clinical Neuroscience - October 16, 2018 Category: Neuroscience Source Type: research
Impact of small vessel disease on severity of motor and cognitive impairment in Parkinson’s disease
ConclusionsThis study demonstrates an association between SVD and motor impairment, and between vascular risk factors, particularly hypertension, and dementia in PD and highlights the need to manage vascular co-morbidities in PD patients.
Source: Journal of Clinical Neuroscience - October 14, 2018 Category: Neuroscience Source Type: research
Activation of mirror neuron system during gait observation in sub-acute stroke patients and healthy persons
In this study, we sequentially enrolled five sub-acute stroke patients who had undergone gait training and nine healthy persons. We used fMRI to detect neuronal activation during gait observation. During the observation period in the stroke group, neural activity in the left inferior parietal lobule, right and left inferior frontal gyrus was significantly higher than during the rest period. In the healthy group, neural activity in the left inferior parietal lobule, left inferior frontal gyrus, left middle frontal gyrus, left superior temporal lobule and right and left middle temporal gyrus was significantly higher than dur...
Source: Journal of Clinical Neuroscience - October 12, 2018 Category: Neuroscience Source Type: research
Acute reversal of dabigatran with Idarucizumab for intravenous thrombolysis as acute stroke treatment
We describe the case of a 73 year old male with AIS and active dabigatran use. Idarucizumab was administered per an approved medical center protocol and the patient was subsequently treated with IV rt-PA. The patient had a severe stroke with no other contraindications to IV rt-PA other than dabigatran use. The patient was administered Idarucizumab and IV rt-PA was given. Within 24 h of treatment, the patient had minimal stroke deficits. Imaging revealed a right middle cerebral artery patchy infarct. The patient was restarted on dabigatran therapy for his atrial fibrillation and was discharged to a skilled nursing facil...
Source: Journal of Clinical Neuroscience - October 9, 2018 Category: Neuroscience Source Type: research
Impact of venous thromboembolism during admission for meningioma surgery on hospital charges and postoperative complications
Publication date: Available online 9 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Eleonora F. Spinazzi, Darshan Shastri, Milap Raikundalia, Nicole A. Silva, Jean Anderson Eloy, James K. LiuAbstractSurgical resection of meningiomas has been associated with high rates of venous thromboembolic events (VTE) as compared with all other intracranial tumors. There is a paucity of data regarding the clinical complications and comorbidities associated with this cohort yet the underlying pathophysiological mechanism for this tumor-specific finding remains unclear. Our goal was to determine the various impacts of VTE...
Source: Journal of Clinical Neuroscience - October 9, 2018 Category: Neuroscience Source Type: research
Predictive value of plasma matrix metalloproteinase-9 concentrations for spontaneous haemorrhagic transformation in patients with acute ischaemic stroke: A cohort study in Chinese patients
Publication date: Available online 2 October 2018Source: Journal of Clinical NeuroscienceAuthor(s): Ruozhen Yuan, Song Tan, Deren Wang, Simiao Wu, Xinhui Cao, Shihong Zhang, Bo Wu, Ming LiuAbstractWhether matrix metalloproteinase 9 (MMP-9) concentrations in plasma predict risk of spontaneous haemorrhagic transformation (sHT) in acute ischaemic stroke is unclear. From 1 March 2003 to 27 February 2006, patients with acute ischaemic stroke admitted to West China Hospital within 24 h of onset and healthy controls were enrolled and blood samples obtained. Plasma MMP-9 concentrations were determined using enzyme-linked immunos...
Source: Journal of Clinical Neuroscience - October 4, 2018 Category: Neuroscience Source Type: research
Comparison of magnetic resonance spectroscopy (MRS) with arterial spin labeling (ASL) in the differentiation between mitochondrial encephalomyopathy, lactic Acidosis, plus stroke-like episodes (MELAS) and acute ischemic stroke (AIS)
Publication date: September 2018Source: Journal of Clinical Neuroscience, Volume 55Author(s): Xiaodi Li, Yuzhou Wang, Zhanhang Wang, Jianjun Lu, Yan Xu, Jinlong Ye, Zuying Kuang, Bo Li, Mengqiu Pan, Wenming Chen, Shuisheng Lu, Ziyang Zhou, Lina Cheng, Honghao WangAbstractTo compare the utility and limitation of magnetic resonance spectroscopy (MRS) and arterial spin labeling (ASL) in the differentiation between mitochondrial encephalomyopathy, lactic acidosis, plus stroke-like episodes (MELAS) and acute ischemic stroke (AIS), a retrospective review of 17 MELAS and 26 AIS patients were performed. In all patients both MRS an...
Source: Journal of Clinical Neuroscience - October 4, 2018 Category: Neuroscience Source Type: research
Association of serum lipids with clinical outcome in acute ischaemic stroke: A systematic review and meta-analysis
This study aimed at assessing the association between serum lipid and clinical outcomes in acute ischaemic stroke. Relevant data were obtained from Cochrane Library, PubMed and Web of Science databases. The heterogeneity of pooled results was determined by the Cochran’s Q test and Higgins I-squared statistic. The random-effect model was performed to calculate the pooled results if PH < 0.05 for Q-test, otherwise the fixed-effect model was applied. The primary results were death, and the secondary were recurrence, dependency, mRS score ≥3, and early neurological deterioration. A total of 21 full-text studies was...
Source: Journal of Clinical Neuroscience - September 20, 2018 Category: Neuroscience Source Type: research
Ability of the Khorana score to predict recurrent thromboembolism in cancer patients with ischemic stroke
In this study, the Khorana score had poor discriminatory ability for predicting RTE in cancer patients with AIS. Future research is needed to identify better methods for predicting RTE in this high-risk population.
Source: Journal of Clinical Neuroscience - August 23, 2018 Category: Neuroscience Source Type: research
Predictors of 30-day mortality after endovascular mechanical thrombectomy for acute ischemic stroke
ConclusionWe observed a moderate rate of 30-day mortality after EMT at an academic CSC. Older age, higher baseline NIHSS score, higher NIHSS score at 24 h after thrombectomy, and lower rates of successful revascularization were predictive of 30-day mortality in univariate analysis. Further efforts to identify modifiable risk factors of mortality are warranted.
Source: Journal of Clinical Neuroscience - August 23, 2018 Category: Neuroscience Source Type: research
Association of lower leukocyte count before thrombolysis with early neurological improvement in acute ischemic stroke patients
Publication date: Available online 17 August 2018Source: Journal of Clinical NeuroscienceAuthor(s): Canhui Tian, Zhong Ji, Wei Xiang, Xiaomei Huang, Shengnan Wang, Yongmin Wu, Suyue Pan, Liang Zhou, Zhen DengAbstractEarly neurological improvement (ENI) after thrombolysis in acute ischemic stroke is associated with a favorable long-term outcome. With the goal to evaluate ENI, we aimed to investigate whether ENI bears a relationship with routine blood tests before thrombolysis. A total of 240 patients with confirmed early ischemic stroke and intravenous recombinant tissue plasminogen activator (rtPA) treatment were enrolled ...
Source: Journal of Clinical Neuroscience - August 17, 2018 Category: Neuroscience Source Type: research
Impact of putamen stroke on task context updating: Evidence from P300 brain waves
Publication date: Available online 1 August 2018Source: Journal of Clinical NeuroscienceAuthor(s): Li-Chuan Hsu, Sui-Foon Lo, Chia-Yao Lin, Fen-Fen Chen, Yu-Chien Lo, Li-Wei Chou, Chih-Lan Kuo, Yi-Min TienAbstractAccording to the context updating theory, the oddball P300 component indexes brain activities underlying revision of the mental representation induced by incoming stimuli. It involves an attention-driven comparison process that evaluates the representation of the previous event in working memory. Delayed latencies have been reported for various types of stroke such as unilateral thalamic stroke. We investigated me...
Source: Journal of Clinical Neuroscience - August 2, 2018 Category: Neuroscience Source Type: research
Internal carotid artery dissection without intracranial infarct following a minor shoulder trauma: The second pediatric case and review of the literature
ConclusionIn carotid artery dissections, prodromal symptoms such as transient ischemic attack, like in our patient, are rarely present in children. For good long term outcomes, it is very important to suspect, diagnose and initiate appropriate treatment in a rapid manner in carotid artery dissection before severe neurological findings such as acute ischemic stroke develops.
Source: Journal of Clinical Neuroscience - July 22, 2018 Category: Neuroscience Source Type: research
