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Total 3153 results found since Jan 2013.

Implementing a Publically Funded Regional Telestroke Network (P1.279)
Conclusions:The NZ based regional telestroke pilot resulted in dramatic improvements in out-of hours thrombolysis access for non-metropolitan based stroke patients. Upon pilot completion a regionally funded service will ensure long-term sustainability and encourage active use of the telestroke service to maximise patient benefit.Study Supported by: New Zealand Ministry of HealthDisclosure: Dr. Ranta has nothing to disclose. Dr. Lanford has nothing to disclose. Dr. Busch has nothing to disclose. Dr. Providence has nothing to disclose. Dr. Iniesta has nothing to disclose. Dr. Richmond has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ranta, A., Lanford, J., Busch, S., Providence, C., Iniesta, I., Richmond, V. Tags: Pre-Hospital Stroke, Tele-Stroke, and mHealth Source Type: research

Quality Improvement in Telestroke Interactions (P1.280)
Conclusions:The use of an efficient, widely accessible online NIHSS review improves remote provider examination accuracy and confidence, and telestroke neurologist provider satisfaction.Study Supported by: NADisclosure: Dr. Nasr has nothing to disclose. Dr. Braksick has nothing to disclose. Dr. Brown has nothing to disclose. Dr. Hocker has received personal compensation for writing a Continnuum and being interviewed for Continuum Audio. Dr. Ho has received research support from SAGE Therapeutics
Source: Neurology - April 17, 2017 Category: Neurology Authors: Nasr, D., Braksick, S., Brown, R., Hocker, S. Tags: Pre-Hospital Stroke, Tele-Stroke, and mHealth Source Type: research

Hyperacute Carotid Stenting for Acute Ischemic Stroke After Systemic Thrombolysis with IV rt-PA (P1.282)
Conclusions:These 2 cases demonstrate a successful use of hyperacute carotid stenting and antiplatelet load in patients who received systemic thrombolysis with IV rt-PA. Both had excellent outcomes and no complications. This management may be considered in patients with similar clinical and imaging characteristics.Disclosure: Dr. Marulanda-Londoño has nothing to disclose. Dr. DeLeon-Bendetti has nothing to disclose. Dr. Ortiz has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Marulanda-Londono, E., DeLeon-Bendetti, A., Ortiz, G. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Paradoxical Embolism in the Setting of Inferior Vena Cava Filter Removal (P1.283)
Conclusions:Although clinically relevant events secondary to IVC filter migration and fracture are rare, they can be life-threatening. Care should be taken when choosing to place these devices, and alternative therapies should be considered when possible. They should be removed when no longer needed, as fracture rates are increased with longer dwell times. Up to half of complications can be avoided with retrieval within 3 months.Disclosure: Dr. Yost has nothing to disclose. Dr. Klaas has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Yost, M., Klaas, J. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Successful endovascular stroke therapy in a 103-year-old woman (P1.284)
Conclusions:The patient in our report presented within 3 h of acute stroke onset secondary to a large vessel occlusion and had very favorable imaging without any early ischemic changes. She also lived an independent functional life with a robust family support structure. To our knowledge, this is the oldest patient to undergo a successful stroke intervention, and the purpose of this report was to document that in carefully selected patients, endovascular therapy may become a feasible option. Other than the clinical and imaging criteria typically utilized for patient selection, including their social, cognitive, and functio...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Duru, U., Boo, S., Rai, A., Smith, M. Tags: Cerebrovascular Disease Case Reports I Source Type: research

4-year-old boy with acute ischemic stroke treated with intravenous tissue plasminogen activase. (P1.285)
Conclusions:The TIPS trial is underway, which utilizes a classic safety dose finding method to select a safe dose of IV tPA. The child in our case was successfully treated with a dose of 0.75 mg/kg of IV tPA. It has been suggested the appropriate dose may actually be higher than the standard used in adults due to the developmental trajectory of the fibrinolytic system during childhood, as children have lower endogenous tPA and higher plasminogen activator inhibitor-1 levels.Disclosure: Dr. Derani has nothing to disclose. Dr. Kassab has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Derani, T., Kassab, M. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Aortic Valvular Papillary Fibroelastoma Leading to Acute Ischemic Stroke in a Pediatric Patient (P1.286)
Conclusions:Previously published cases of children with IS and PF have identified the mitral valve as the site of the PF. Our case demonstrates that aortic valvular PF can be associated with IS in pediatric patients. Resection of symptomatic PF is recommended to prevent further cardio-embolic strokes.Disclosure: Dr. Farooqui has nothing to disclose. Dr. Mannel has nothing to disclose. Dr. Silliman has received research support from Sanofi Genzyme, Biogen Idec, Bristol Myers and Novartis.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Farooqui, I., Mannel, R., Silliman, S. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Subcortical aphasias-questioning validity of aphasia as a cortical infarct sign (p1.287)
Conclusions:Given that a small subcortical infarction can present as pure aphasia, the belief that aphasia is always a sign of a cortical infarct is unfounded and should be revisited.Disclosure: Dr. Kaur has nothing to disclose. Dr. Culebras received personal compensation in an editorial capacity for Medlink and UpToDate.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kaur, G., Culebras, A. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Rare Cases of Thrombotic and Embolic Stroke with Hypereosinophilia (P1.295)
Conclusions:Hypereosinophilia can cause both embolic and thrombotic strokes as evidenced by our patients. The etiology of embolic stroke may be due to the direct eosinophilic damage to the endocardium or by the release of eosinophilic basic proteins which initiate endomyocardial necrosis, making the heart a potential source of emboli. Causes of thrombogenicity are multifactorial including the release of tissue factor from specific granules, inactivation of thrombomodulin by binding to the major basic protein, endothelial damage or by elevation of fibrinogen levels. The individual presentations (thrombotic/embolic) will alt...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Finelli, D., Shoamanesh, A., Perera, K. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Recurrent ischemic strokes as the initial presentation of thrombotic thrombocytopenic purpura with normal platelets: a case report. (P1.296)
Conclusions:Recurrent strokes in multiple vascular territories should prompt suspicion of hypercoagulable, cardioembolic, or vasculitis/opathy. TTP can be a cause of hypercoagulability in patients with cryptogenic stroke even without major hematologic abnormalities. TTP is treatable with plasma exchange and immunosuppression. Thus, one must consider TTP even in the absence of hematologic abnormalities, especially in a young patient with no stroke risk factors and otherwise negative stroke work-up.Disclosure: Dr. Horton has nothing to disclose. Dr. Doyle has nothing to disclose. Dr. Powell has received research support from...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Horton, L., Doyle, A., Powell, C., Gebreyohanns, M. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Eagles Syndrome: Viewing a Rare Disorder from a New Perspective (P1.297)
Conclusions:This case not only exhibits an uncommon etiology for stroke, but also introduces an innovative method to visualize complex neuroanatomy. Given the relatively low cost and harmless creation of the model, this option may prove beneficial in other similar cases.Disclosure: Dr. Shah has nothing to disclose. Dr. Miller has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Shah, K., Miller, D. J. Tags: Cerebrovascular Disease Case Reports I Source Type: research

Multiplanar CT Reconstruction to Aid in Recognition of the MCA "Dot" Sign: The Sagittal String Sign (P1.302)
Conclusions:The MCA "dot" sign is often a sign of poor prognostic outcomes in ischemic stroke patients. This is the first report of using the CT sagittal plane for diagnosis of the MCA "dot" sign. Incorporating multiplanar reconstruction and producing the sagittal plane may lead to a higher sensitivity of the MCA "dot" sign. Further studies incorporating a patient cohort will be needed to determine how much the sagittal plane view augments predictive value of the MCA "dot" sign.Disclosure: Dr. Mannel has nothing to disclose. Dr. Silliman has received research support from Sanofi Genzyme, Biogen Idec, Bristol Myers and Novartis.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mannel, R., Silliman, S. Tags: Cerebrovascular Disease Case Reports I Source Type: research

A Rare Case of Central Nervous System Tuberculosis Presenting as Transient Splenial Lesion: Case Report and Literature Review (P1.320)
Conclusions:Based on literature review, the transient splenial lesion of corpus callosum has never been reported in patients with CNS tuberculosis. The mechanisms underlying transient splenial lesions may due to intramyelinic edema and inflammatory cell infiltration. This hypothesis supported by the MR spectroscopy findings in our patient. Since early diagnosis and treatment can reduce mortality and morbidity, patients with isolated splenial lesion warrant diagnostic tests for CNS tuberculosis.Study Supported by:The authors report no disclosures relevant to the manuscript.Disclosure: Dr. Wu has nothing to disclose. Dr. Che...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wu, J.-W., Chen, S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research

Burden of Cerebrovascular Disease and its association in the clinical characteristics, Incidence and outcomes in the hospitalized patients with Community-Acquired Pneumonia in Louisville, KY (P1.321)
Conclusions:This study documents worse clinical outcomes and significantly increased mortality in the hospitalized patients with community acquired pneumonia and associated cerebrovascular disease.Disclosure: Dr. SirDeshpande has nothing to disclose. Dr. Kolikonda has nothing to disclose. Dr. Peyrani has nothing to disclose. Dr. Ramirez has nothing to disclose. Dr. Arnold has nothing to disclose. Dr. Wiemken has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: SirDeshpande, P., Kolikonda, M., Peyrani, P., Ramirez, J., Arnold, F., Wiemken, T. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research

Streptococcus pneumoniae meningitis and intracranial vasculopathy: Clinical correlation with improving transcranial Doppler hemodynamics (P1.322)
Conclusions:Antibiotic treatment for S. pneumoniae meningitis correlated with improvement in clinical status and TCD hemodynamics. Serial TCDs may be a potentially useful strategy in the management of bacterial meningitis.Disclosure: Dr. Idris has nothing to disclose. Dr. Tai has nothing to disclose. Dr. Tan has nothing to disclose. Dr. Tan has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Idris, M. I., Tai, S. M. L., Tan, C. T., Tan, K. S. Tags: Autoimmunity with Infection, Syphilis, Lyme, Tuberculosis, and other Bacteria Source Type: research