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Source: Neurology
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Total 3153 results found since Jan 2013.
Edaravone (MCI-186) for the Treatment of Amyotrophic Lateral Sclerosis (ALS): A Posthoc Analysis of Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) by Domain and Individual Items (P3.130)
Conclusions:A generally favorable descriptive effect for edaravone was observed during posthoc assessment of the ALSFRS-R by domain and individual items.Study Supported by: MTPC was responsible for funding and conduct of the study. MTDA was responsible for executing this analysis.Disclosure: Dr. Palumbo has received personal compensation for activities with Mitsubishi Tanabe as an employee. Dr. Palumbo holds stock options in Actelion Clinical Research, Inc., in which his spouse is a full-time pharmaceutical researcher and receives stock options as partial compensation for work performed. Dr. Takei has received personal com...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Palumbo, J. M., Takei, K., Tsuda, K., Liu, S. Tags: Neuromuscular and Clinical Neurophysiology (EMG): Motor Neuron Disease I Source Type: research
A Common Data Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke and National Library of Medicine Cerebral Aneurysms and Subarachnoid Hemorrhage Common Data Elements Version 1.0 Recommendations (P3.169)
Conclusions:NINDS encourages the use of CDEs by the clinical research community in order to standardize data collection across studies. The NINDS CDEs are a continually evolving resource, requiring updates as research advancements indicate. These newly developed SAH CDEs serve to be a valuable starting point for researchers and facilitate streamlining and sharing data. Information provided at this meeting will include examples of how the SAH CDEs and CRFs may be used by a research study, demonstrations of navigating the NINDS CDE and NIH CDE Repository websites and submitting feedback.Study Supported by: This project was f...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Sheikh, M., Alai, S., Esterlitz, J., Amos, L., Ludet, C., Odenkirchen, J., Suarez, J. Tags: Neurocritical Care: NICU Issues Source Type: research
"I believe in miracles": Implications for the Neuro-ICU (P3.181)
Conclusions:Preliminary data lack robustness to make definitive conclusions, however suggest possibility of shorter hospital LOS in those who don’t believe in miracles. Involvement of spiritual care early in the ICU may assist in important decision making with patients and family members.Disclosure: Dr. Ramineni has nothing to disclose. Dr. Dangayach has nothing to disclose. Dr. Griffiths has nothing to disclose. Dr. Keogh has nothing to disclose. Dr. Wheelwright has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Gidwani has nothing to disclose. Dr. Ahmad has nothing to disclose. Dr. Bederson has nothin...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ramineni, A., Dangayach, N., Griffiths, S., Keogh, M., Wheelwright, D., Sharma, V., Gidwani, U., Ahmad, J., Bederson, J., Mocco, J., Mayer, S. Tags: Neurocritical Care: NICU Issues Source Type: research
Language competence and brain structural integrity in children with perinatal stroke (P3.205)
Conclusions:The right hemisphere (RH) may play a more prominent role in language development than commonly assumed. This is consistent with other studies indicating early RH involvement in language and at odds with the assumption that the left hemisphere is "hard-wired" to be dominant for language from birth. It may also be the case that complex interactions between hemispheres are required to facilitate language development.Study Supported by:Supported by NIH #P50 NS22343 (D Trauner, PI)Disclosure: Dr. Trauner has received research support from Novartis. Dr. Vu has nothing to disclose. Dr. Brown has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Trauner, D., Vu, L., Brown, T. Tags: Child Neurology I Source Type: research
Added value of interleukin-1 blockade to hypothermia in neonatal encephalopathy due to inflammatory-sensitized hypoxia-ischemia: a preclinical study. (P3.212)
Conclusions:Our results demonstrate that IL-1Ra (50mg/kg) has an added value to the neuroprotective effect of HT in LPS+HI-induced NE. This project could open new therapeutic avenues to prevent CP.Study Supported by:CIHR, FRQ-S, Heart and Stroke Foundation, "Tranzyme-Pharma" scholarship fom Université de Sherbrooke, and Foundation of Stars.Disclosure: Dr. Chevin has nothing to disclose. Dr. Guiraut has nothing to disclose. Dr. Sebire has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chevin, M., Guiraut, C., Sebire, G. Tags: Child Neurology I Source Type: research
Recurrent transient hemiparesis and a novel ATP1A2 mutation (P3.220)
Conclusions:This case identifies a novel, potentially pathogenic mutation of the ATP1A2 gene corresponding to a phenotype of a rare migraine variant and contributes to our evolving understanding of migraine molecular genetics and pathophysiology.Study Supported by:Disclosure: Dr. Stredny has nothing to disclose. Dr. Winden has nothing to disclose. Dr. Danehy has nothing to disclose. Dr. Robertson has nothing to disclose. Dr. Trenor has nothing to disclose. Dr. Rivkin has nothing to disclose. Dr. Lehman has nothing to disclose. Dr. Bernson-Leung has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Stredny, C., Winden, K., Danehy, A., Robertson, R., Trenor, C., Rivkin, M., Lehman, L., Bernson-Leung, M. Tags: Child Neurology I Source Type: research
Stroke in women: Results from the Mashhad Stroke Incidence Study (MSIS), a population based study in the Middle-East (P3.251)
Conclusions:A relatively higher rate of stroke in women needs a prompt action in primary and secondary prevention of stroke in developing countries. Larger population-based studies are required to resolve the underlying reasons for higher incidence rate among women, in particularly for ischemic and intracerebral hemorrhage types in this age band.Disclosure: Dr. Amiri has nothing to disclose. Dr. Azarpazhooh has nothing to disclose. Dr. Saber has nothing to disclose. Dr. Shoamanesh has nothing to disclose. Dr. Behrouz has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Amiri, A., Azarpazhooh, M. R., Saber, H., Shoamanesh, A., Behrouz, R. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Circadian variation in patients with cryptogenic stroke and patent foramen ovale (P3.252)
Conclusions:These data suggest that strokes occur more frequently in the morning hours in patients with CS and PFO. Hypertension is significantly lower in patients with symptom onset between 0601 and 1200, which may further imply embolism as the potential mechanism of stroke in these patients. Further studies with larger datasets are required to investigate the circadian variation of PFO-attributable strokes.Disclosure: Dr. Daneshmand has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Daneshmand, A., Thaler, D. Tags: Cerebrovascular Disease Epidemiology Source Type: research
The frequency of headache in patients in patients with first- ever ischemic stroke (p3.253)
Conclusions:Headache was much more common among patients with infarcts in the posterior circulation than in patients in whom the anterior circulation was involved. Headache was more common when the cause of stroke was large artery disease.Disclosure: Dr. Dobi has nothing to disclose. Dr. Basha has nothing to disclose. Dr. RANXHA has nothing to disclose. Dr. TAKA has nothing to disclose. Dr. ROCI has nothing to disclose. Dr. KAPISYZI has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Dobi, D., Basha, E., RANXHA, E., TAKA, O., ROCI, E., KAPISYZI, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Elevated Serum Creatinine Predicts Higher Mortality in Stroke Patients (P3.254)
Conclusions:Abnormal renal function at the time of stroke admission was noted in older male patients with hypertension and reduced pre-stroke eGFR. High stroke admission Cr level was a significant predictor of mortality. High risk patients needs to be identified and aggressively treated to reduce mortality risks.Disclosure: Dr. Ibrahim has nothing to disclose. Dr. Rayyis has nothing to disclose. Dr. Almekhlafi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ibrahim, B., Rayyis, L., Almekhlafi, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Outcome and Prognosis of Middle Cerebral Artery Occlusive Disease in a Sample of Egyptian Patients. (P3.255)
Conclusions:Symptomatic MCA stenosis is associated with higher risk of recurrent cerebral stroke.Disclosure: Dr. Elsaid has nothing to disclose. Dr. El-Mitwalli has nothing to disclose. Dr. Farrag has nothing to disclose. Dr. Abdel Salam has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Elsaid, N., El-Mitwalli, A., Farrag, M., Abdel Salam, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Prevalence of Ischemic Stroke in Cohort of Ulcerative Colitis Patients (P3.256)
Conclusions:In our cohort of ulcerative colitis patients, prevalence of ischemic stroke was 6000 per 100,000 which is not significantly different than the general population. However, in the under 60 age group prevalence of ischemic stroke is twice as that of the general population. Further population based cohort studies are needed to elucidate actual incidence in this high-risk group for early intervention.Study Supported by: No funding.Disclosure: Dr. Horta has nothing to disclose. Dr. Tore has nothing to disclose. Dr. Kent has nothing to disclose. Dr. Ezzeddine has received personal compensation for activities with Air...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Horta, E., Tore, H., Kent, N., Ezzeddine, M., Streib, C., Reshi, R. Tags: Cerebrovascular Disease Epidemiology Source Type: research
To describe symptomatology and etiological factors of posterior fossa strokes involving only the basilar artery. (P3.257)
Conclusions:Muscle weakness, language changes were the primary symptoms recorded when patients presented with posterior fossa strokes involving only the basilar artery. LVAT and cardio-embolism were the primary etiologies. This study elucidates symptoms to look for when patients present with muscle weakness as well as language changes, and emphasizes the possibility of cardiac causes of posterior fossa strokes involving purely the basilar artery.Study Supported by:The patients evaluated with only basilar stroke and at least one of the following symptoms: 72.6% (53/73) muscle weakness, 64.4% (47/73) language changes, 40.0% ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Parand, L., Jillella, D., Zafar, A. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Understanding race-ethnic disparities in hospital arrival after stroke symptom onset (P3.259)
Conclusions:Limited knowledge of stroke symptoms may partially explain disparity between race-ethnic groups in hospital arrival.Disclosure: Dr. Springer has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Springer, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research
Clinical features of acute stroke in young adults - a qualitative study of patient experiences (P3.260)
Conclusions:Young adults with acute stroke may have atypical clinical features that interfere with accessing care and receiving an accurate diagnosis.Disclosure: Dr. Jones has nothing to disclose. Dr. Huggins has nothing to disclose. Dr. Thaler has received personal compensation for activities with St. Jude Medical WL and Gore Associates as a consultant. Dr. Han has nothing to disclose. Dr. Leung has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Jones, D., Huggins, H., Thaler, D., Han, P., Leung, L. Tags: Cerebrovascular Disease Epidemiology Source Type: research
