Recurrent ischemic strokes as the initial presentation of thrombotic thrombocytopenic purpura with normal platelets: a case report. (P1.296)

We describe a case of a 61 year-old woman presenting with recurrent strokes in multiple vascular territories over seven weeks. Initially, she had no hematologic abnormalities and an unremarkable work-up including cardiac evaluation (TTE, TEE, TCD, cardiac MRI, 30-day loop monitor), vascular (CTA, MRA, 4-vessel angiogram), hypercoagulable panel, and scans for occult malignancy. After seven weeks her platelets remained normal (183), but the presence of a mild anemia (HGB 9.7, HCT 30), mildly elevated LDH (261), and "slight" schistocytes noted prompted suspicion for TTP. ADAMTS13 activity was
Source: Neurology - Category: Neurology Authors: Tags: Cerebrovascular Disease Case Reports I Source Type: research

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Publication date: Available online 31 March 2020Source: Neurophysiologie CliniqueAuthor(s): Karim Jamal, Stéphanie Leplaideur, Chloé Rousseau, Sébastien Cordillet, Annelise Moulinet Raillon, Simon Butet, Armel Cretual, Isabelle Bonan
Source: Neurophysiologie Clinique - Category: Neuroscience Source Type: research
Authors: Sayad A, Dehaghi MO, Taheri M, Fallah H, Arsang-Jang S, Shadnoush M, Ghafouri-Fard S, Hamidieh AA Abstract Fanconi anemia includes a number of clinically and genetically diverse disorders all of them being associated with genomic instability. Some previous studies reported higher frequencies of certain HLA alleles in patients with Fanconi anemia. In the current study, we genotyped HLA-A/B/DRB1 alleles in 40 Iranian patients with Fanconi anemia. We also genotyped these alleles in the same number of Iranian sex-matched healthy individuals. The frequency of DRB1*11 was significantly higher in patients compare...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
We present here a complete theoretical study of the phase diagram of two-dimensional silicon-carbon binaries. To scan the composition range, we employ an {\it ab initio} global structural prediction method,... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - Category: Chemistry Authors: Source Type: research
We present a case of synchronous bilateral renal cell carcinoma and prostate carcinoma in a 62 year old man. In a fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG PET) scan, the left renal mass showed intense 18F-FDG uptake with maximum standardized uptake volume (SUVmax) of 8.12, while uptake in the right renal mass was minimal with SUVmax of 2.99. Fluorine-18-FDG uptake in the prostate gland lesion was moderate with SUVmax of 4.19. Histopathologically, both renal tumors were clear cell renal cell carcinoma with International Society of Urological Pathology (ISUP) Grade 2 and 3 for the right and left k...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
We presented a rare case of primary pleural squamous cell carcinoma (SCC) on fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). It manifested as multiple pleural nodules with moderate 18F-FDG uptake and massive pleural effusion on PET/CT. The pathology result supported the primary squamous cell carcinoma. Our case highlighted the SCC should be included as differential diagnosis of the multiple pleural lesions and other differential diagnosis consisted of mesothelioma, solitary fibrous tumor, metastases. PMID: 32222735 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
Authors: Stević M, Vlajković M, Veličković F, Stanojević G, Nestorović M, Petrović F Abstract A 69 year old patient was admitted to hospital with massive gastrointestinal hemorrhage. The clinical presentation of the patient, except for bleeding, was dominated by the presence of neurofibromatosis type 1 - Von Recklinghausen disease. The patient was referred to multislice computed tomography (CT) angiography, magnetic resonance imaging (MRI), esophagogastroduodenoscopy and colonoscopy, which were performed without successful detection of the bleeding site. The MRI examination showed the existence of a tumor lo...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
We present a case of a 79 year old patient with a medical history of unilateral nerve-sparing radical prostatectomy due to a pT3aN0 (Gleason score 7) prostate carcinoma. Because of slightly elevated prostate specific antigen (PSA) level (0.35ng/dL), a fluorine-18-prostate specific membrane antigen (18F-PSMA)-1007 positron emission tomography/computed tomography (PET/CT) scan was performed, showing no signs of malignant recurrence. However, a moderately PSMA-avid nodular lesion was observed in the left occipital region with homogeneous contrast enhancement, suggestive for a meningioma, which was confirmed on magnetic resona...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
Authors: Sachpekidis C, Exadaktylou P, Katsampoukas D, Moralidis E, Arsos G Abstract Peritoneal lymphomatosis, defined as the disseminated intraperitoneal lymphomatous infiltration, is a rare presentation usually of non-Hodgkin lymphoma and is associated with aggressive histological subtypes of the malignancy. Recently, the term "peritoneal super scan" has been introduced in positron emission tomography/computed tomography (PET/CT) in a patient with Burkitt lymphoma to describe hypermetabolic lymphomatous involvement of the entire peritoneum, leading to suppression of tracer uptake in organs with otherwis...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
Authors: Altini C, Lavelli V, Ruta R, Ferrari C, Nappi AG, Pisani A, Sardaro A, Rubini G Abstract Nuclear Medicine multimodality imaging, such as positron emission tomography/computed tomography PET/CT, refers to metabolic tissue characteristics integrated with anatomical details. Fluorine-18-fluorodeoxyglucose (18F-FDG) is the most diffuse radiopharmaceutical and its application is spreading beyond the area of oncology. The causes of high 18F-FDG uptake that were once considered false positives have been identified and the new knowledge about them led to non-cancerous pathologies that can be studied by 18F-FDG PET...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
CONCLUSION: Carbon-11-choline PET was found have a greater correlation with Gleason score than DWI and is considered to be more useful to predict a higher score in patients with prostate cancer. Fluorine-18-FDG PET was limited because of low sensitivity. PMID: 32222730 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
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