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Drug: Melatonin
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Total 139 results found since Jan 2013.
Stem cell survival after transplantation impacted by melatonin pre-treatment
When melatonin, a hormone secreted by the pineal gland, was used as a pre-treatment for mesenchymal stem cells (MSCs) prior to their transplantation into the brains of laboratory animals to repair damage from stroke, researchers in China found that the stem cells survived longer after transplantation. Previous studies had shown that 80 percent of transplanted MSCs died within 72 hours of transplantation. By contrast, the melatonin pre-treatment "greatly increased" cell survival, said the researchers...
Source: Health News from Medical News Today - July 24, 2013 Category: Consumer Health News Tags: Stroke Source Type: news
Melatonin pre-treatment is a factor that impacts stem cell survival after transplantation
(Cell Transplantation Center of Excellence for Aging and Brain Repair) Melatonin used as a pre-treatment for mesenchymal stem cells, prior to their transplantation into the brains of laboratory animals to repair damage from stroke, helped stem cells survive longer after transplantation. The melatonin pre-treatment greatly increased cell survival when contrasted with previous studies in which 80 percent of transplanted MSCs died within 72 hours of transplantation. Study results demonstrated that the melatonin pre-treated MSCs had enhanced survival under oxidative stimulation by activating the Erk1/2 pathway.
Source: EurekAlert! - Medicine and Health - July 22, 2013 Category: Global & Universal Source Type: news
Pineal Calcification Is Associated with Symptomatic Cerebral Infarction
Conclusions: Pineal calcification may be a potential new contributor to cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2013 Category: Neurology Authors: Amnat Kitkhuandee, Kittisak Sawanyawisuth, Nutjaree Pratheepawanit Johns, Jaturat Kanpittaya, Jeffrey Johns Tags: Original Articles Source Type: research
Melatonin Receptor Agonists for Treating Delirium in Elderly Patients with Acute Stroke
Conclusions: Melatonin receptor agonists may be effective for the treatment of delirium in elderly patients with acute stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2012 Category: Neurology Authors: Tsuyoshi Ohta, Kenichi Murao, Kosuke Miyake, Koichiro Takemoto Tags: Original Articles Source Type: research
