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Condition: Heart Failure
Drug: Beta-Blockers
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Total 190 results found since Jan 2013.
Sudden cardiac death in transposition of the great arteries with a Mustard or Senning baffle: the myocardial ischemia hypothesis
Purpose of review: The literature on sudden death in transposition of the great arteries (D-TGA) with atrial switch surgery is reviewed and a pathophysiological mechanism is proposed.
Recent findings: Over 80% of sudden deaths in patients with D-TGA and Mustard or Senning baffles occur during exercise. Factors most consistently associated with ventricular arrhythmias and sudden death include heart failure parameters and atrial arrhythmias. Atrial arrhythmias have been observed to trigger malignant ventricular arrhythmias. Exercise may promote 1 : 1 conduction, with inordinately high ventricular rates. Reconstructed in...
Source: Current Opinion in Cardiology - December 1, 2016 Category: Cardiology Tags: PEDIATRICS: Edited by Mitchell I. Cohen Source Type: research
Turkish registry for diagnosis and treatment of acute heart failure: TAKTIK study.
CONCLUSION: Compared to previous data collected around the world, AHF patients in Turkey were younger, had more frequently valvular heart disease as the underlying cause, and were more noncompliant with medical treatment, but overall mortality was lower. Drugs shown to reduce mortality, and which also form the basis of guideline-directed medical therapy, are still used inadequately.
PMID: 28045409 [PubMed - in process]
Source: Turk Kardiyoloji Dernegi arsivi - November 30, 2016 Category: Cardiology Authors: Eren M, Zoghi M, Tuncer M, Çavuşoğlu Y, Demirbağ R, Şahin M, Serdar OA, Onrat E, Mutlu H, Dursunoğlu D, Yılmaz MB, Temizhan A, TAKTIK Investigators Tags: Turk Kardiyol Dern Ars Source Type: research
Beta-blockers are associated with decreased in-hospital mortality and stroke in acute decompensated heart failure: Findings from a retrospective analysis of a 22-year registry in the Middle East (1991-2013).
CONCLUSIONS: Previous beta-blockade therapy in patients presenting with ADHF decreases intra-hospital mortality and the incidence of CV events and transient ischemic attacks. Moreover, non-withdrawal of beta-blockers during hospitalization has a favorable outcome.
PMID: 27550053 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - August 21, 2016 Category: Drugs & Pharmacology Authors: Khalil CA, Al Suwaidi J, Singh R, Asaad N, Abushahba G, Kunju U, Al-Qahtani A, AlBinali HA Tags: Curr Vasc Pharmacol Source Type: research
Impact of Chronic Nitrate Therapy in Patients With Ischemic Heart Failure
Conclusion:
Long-term nitrates use in patients with ischemic HF was associated with higher occurrence of ischemic events, defined as fatal or nonfatal myocardial infarction or stroke. Our results, although from a retrospective analysis, do not support a role for chronic nitrate use in HF.
Source: Journal of Cardiovascular Pharmacology and Therapeutics - August 4, 2016 Category: Cardiology Authors: Moreira-Silva, S., Urbano, J., Nogueira-Silva, L., Bettencourt, P., Pimenta, J. Tags: Clinical Study Source Type: research
Pattern of antihypertensive therapy among diabetic hyperten- sive patients in zewditu memorial hospital, addis ababa.
CONCLUSION: The pattern of antihypertensive drug therapy in our patients was consistent with the current treatment guidelines. However, the majority of diabetic-hypertensive patients did not reach target blood pressure.
PMID: 27476227 [PubMed - in process]
Source: Ethiopian Medical Journal - August 3, 2016 Category: African Health Tags: Ethiop Med J Source Type: research
Gender Discrepancy in Diabetic Patients Hospitalized With Heart Failure: Does Age Matter?
Conclusions: In DHF, female gender is characterized by having a high prevalence of metabolic syndrome components. Also, females are more likely to have better Left ventricular ejection fraction but less likely to receive cardiovascular evidence based medications. There is no significant difference in the overall hospital mortality between both genders, however, in the younger age; males have a significantly higher mortality.
Source: Critical Pathways in Cardiology - August 2, 2016 Category: Cardiology Tags: Original Studies Source Type: research
Pulmonary Hypertension due to Radiofrequency Catheter Ablation (RFCA) for Atrial Fibrillation: The Lungs, the Atrium or the Ventricle?
Atrial fibrillation is the most common heart rhythm disorder affecting around 2.5 million people in United States. It is characterised by rapid and irregular beating of both the atria resulting in the similar ventricular response. It is associated with the risk of stroke and heart failure resulting in increased morbidity and mortality [1]. The treatment of atrial fibrillation involves rate control with ant-arrhythmic drugs like beta blockers, digoxin and amiodarone. Cardioversion is recommended in case of haemodynamic instability or after failure of pharmacological therapies.
Source: Heart, Lung and Circulation - July 15, 2016 Category: Cardiology Authors: Isha Verma, Hemantkumar Tripathi, Rutuja Rajanikant Sikachi, Abhinav Agrawal Tags: Review Source Type: research
Clinical presentation, management, and outcomes in the Indian Heart Rhythm Society-Atrial Fibrillation (IHRS-AF) registry
Conclusions In India, AF patients are younger and RHD is still the most frequent etiology. Almost two-third of the patients have persistent/permanent AF. At one-year follow-up, there is a significant mortality and morbidity in AF patients in India.
Source: Indian Heart Journal - July 10, 2016 Category: Cardiology Source Type: research
Better Treatments To Reverse Congestive Heart Failure
Take it easy… stay in bed. That’s what most doctors tell patients with congestive heart failure. I can’t think of worse advice.
What’s Congestive Heart Failure?
Congestive heart failure (CHF) means your heart can’t pump enough blood for your body’s needs. Blood builds up behind the heart. Fluids accumulate in the lungs and make you weak, tired and short of breath. Less blood flowing to your brain makes you dizzy and confused. Vital organs like your lungs, brain and kidneys begin to shut down.
What Happens When You Have CHF?
A heart with CHF is severely deconditioned. When your heart pu...
Source: Al Sears, MD Natural Remedies - June 13, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news
Treatment of Hypertension in Coarctation of the Aorta
Opinion statement
The treatment of hypertension in coarctation of the aorta (CoA) is ideally managed by early surgical or transcatheter repair to reduce the risk of irreversible aortopathy and refractory hypertension, in addition to other associated sequelae including premature coronary artery disease; stroke; aortic aneurysm, dissection, and rupture; infective endocarditis; and heart failure. The choice of surgical or transcatheter repair is dependent on individual patient considerations. Medical therapy for hypertension due to CoA parallels treatment of essential hypertension with beta blockers, angiotensin-con...
Source: Current Treatment Options in Cardiovascular Medicine - April 18, 2016 Category: Cardiology Source Type: research
Secondary Prevention Beyond Hospital Discharge for ACS: Evidence-based Recommendations
Publication date: Available online 10 March 2016 Source:Canadian Journal of Cardiology Author(s): David H. Fitchett, Shaun G. Goodman, Lawrence A. Leiter, Peter Lin, Robert Welsh, James Stone, Jean Grégoire, Philip Mcfarlane, Anatoly Langer In the last three decades, a better understanding of the pathophysiology of cardiovascular disease has resulted in innovations in the treatment and prevention of its clinical manifestations such as death, myocardial infarction or stroke. Following an acute coronary syndrome there are short and long term risks of subsequent cardiovascular events. This leads to opportunities t...
Source: Canadian Journal of Cardiology - March 11, 2016 Category: Cardiology Source Type: research
Digoxin Use and Adverse Outcomes in Patients With Atrial Fibrillation
Abstract: Digoxin has long been used for rate control in atrial fibrillation (AF); its safety remains controversial.
We performed a literature search using MEDLINE (source PubMed, January 1, 1966, to July 31, 2015) and EMBASE (January 1, 1980, to July 31, 2015) with no restrictions. Studies that reported relative risk (RR) estimates with 95% confidence intervals (CIs) for the associations of interest were included. Pooled effect estimates were obtained by using random-effects meta-analysis.
Twenty-two studies involving 586,594 patients were identified. Patients taking digoxin, as compared with those who took no digoxin, ...
Source: Medicine - March 1, 2016 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Abstract 12: Heart Failure Medications Prescribed at Discharge for Patients With Left Ventricular Assist Devices Session Title: Abstract Oral Session: Quality of Care
Conclusion: Traditional HF therapies are commonly prescribed to LVAD recipients, although less frequently than to advanced HF patients without LVAD support. Aldosterone antagonists are prescribed increasingly to LVAD patients. Further research is needed on the optimal medical regimen for patients with LVADs.
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: Baras Shreibati, J., Sheng, S., Fonarow, G. C., DeVore, A. D., Yancy, C. W., Bhatt, D. L., Peterson, E. D., Hernandez, A., Heidenreich, P. A. Tags: Session Title: Abstract Oral Session: Quality of Care Source Type: research
New therapies for arterial hypertension.
Authors: Pagliaro B, Santolamazza C, Rubattu S, Volpe M
Abstract
Arterial hypertension is the most common chronic disease in developed countries and it is the leading risk factor for stroke, ischemic heart disease, congestive heart failure, chronic renal failure and peripheral artery disease. Its prevalence appears to be about 30-45% of the general population. Recent European guidelines estimate that up to 15-20% of the hypertensive patients are not controlled on a dual antihypertensive combination and they require three or more different antihypertensive drug classes to achieve adequate blood pressure control. The...
Source: Panminerva Medica - January 18, 2016 Category: Journals (General) Tags: Panminerva Med Source Type: research
Prognostic and symptomatic benefits with ivabradine: lessons from the SHIFT trial
Ivabradine, a funny current (If) inhibitor, has been developed for symptomatic therapy of angina and in chronic heart failure (CHF) with low ejection fraction. A large outcome trial, SHIFT (Systolic Heart Failure Treatment with the If inhibitor ivabradine trial), was conducted in patients with EF ≤ 35% in sinus rhythm and increased heart rate ≥70 b.p.m. It demonstrated that the addition of this new compound to the best possible contemporary therapy, including beta-blockers, was associated with a 18% relative risk reduction in the occurrence of cardiovascular mortality or hospitalization for worsening heart failure (H...
Source: European Journal of Heart Failure Supplements - December 16, 2015 Category: Cardiology Authors: Komajda, M. Tags: Articles Source Type: research
