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Specialty: Cardiology
Drug: Beta-Blockers

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Total 184 results found since Jan 2013.

STEMI vs NSTEACS management trends in non-invasive hospital
Conclusion NSTEACS patients in western province of KSA present at an older age are mostly males and have higher prevalence of hypertension and hyperlipidemia compared with STEMI patients. It is therefore important to identify patients with high-risk profile and put implement measures to reduce these factors.
Source: Indian Heart Journal - January 14, 2016 Category: Cardiology Source Type: research

Prognostic and symptomatic benefits with ivabradine: lessons from the SHIFT trial
Ivabradine, a funny current (If) inhibitor, has been developed for symptomatic therapy of angina and in chronic heart failure (CHF) with low ejection fraction. A large outcome trial, SHIFT (Systolic Heart Failure Treatment with the If inhibitor ivabradine trial), was conducted in patients with EF ≤ 35% in sinus rhythm and increased heart rate ≥70 b.p.m. It demonstrated that the addition of this new compound to the best possible contemporary therapy, including beta-blockers, was associated with a 18% relative risk reduction in the occurrence of cardiovascular mortality or hospitalization for worsening heart failure (H...
Source: European Journal of Heart Failure Supplements - December 16, 2015 Category: Cardiology Authors: Komajda, M. Tags: Articles Source Type: research

Association of Patient Enrollment in Medicare Part D With Outcomes After Acute Myocardial Infarction Original Articles
Conclusions— Only half of Medicare-insured patients with AMI were enrolled in Part D by hospital discharge, and their 30-day and 1-year adjusted outcomes did not differ substantially from nonenrollees. There remain opportunities for improvement in medication adherence among patients with prescription drug coverage.
Source: Circulation: Cardiovascular Quality and Outcomes - November 17, 2015 Category: Cardiology Authors: Goyal, A., de Lemos, J. A., Peng, S. A., Thomas, L., Amsterdam, E. A., Hockenberry, J. M., Peterson, E. D., Wang, T. Y. Tags: Myocardial Infarction, Ethics and Policy, Quality and Outcomes Original Articles Source Type: research

Ten year experience of using a novel metabolic protocol in 'off pump' coronary artery bypass revascularization
Conclusions: Off-pump coronary artery bypass coupled with this novel metabolic protocol was associated with a low operative mortality and acceptable perioperative morbidities, including patients with left main coronary artery disease. These benefits are apparent at both short- and medium-term follow up.
Source: Therapeutic Advances in Cardiovascular Disease - November 16, 2015 Category: Cardiology Authors: Perkowski, D. J., Wagner, S., Muller, K., Schneider, J. R., St.Cyr, J. A. Tags: Original Research Source Type: research

High B-Type Natriuretic Peptide Hypertensives at Target Blood Pressure: Potential Role of {beta}-Blockers to Reduce Their Elevated Risk Brief Review
Source: Hypertension - October 7, 2015 Category: Cardiology Authors: Struthers, A. D., George, J. Tags: Cardiovascular Pharmacology, Primary prevention, Cerebrovascular disease/stroke, Other hypertension, Clinical Studies Brief Review Source Type: research

Socioeconomic factors and use of secondary preventive therapies for cardiovascular diseases in South Asia: The PURE study
Conclusion The use of secondary preventive drug therapies in patients with known CHD or stroke in South Asia is low with over 80% receiving none of the effective drug treatments. Low household wealth is the most important determinant.
Source: European Journal of Preventive Cardiology - September 11, 2015 Category: Cardiology Authors: Gupta, R., Islam, S., Mony, P., Kutty, V. R., Mohan, V., Kumar, R., Thakur, J., Shankar, V. K., Mohan, D., Vijayakumar, K., Rahman, O., Yusuf, R., Iqbal, R., Shahid, M., Mohan, I., Rangarajan, S., Teo, K. K., Yusuf, S. Tags: Original scientific papers Source Type: research

Antiplatelet therapy in Takotsubo cardiomyopathy: does it improve cardiovascular outcomes during index event?
Abstract Plasma catecholamines may play an important role in Takotsubo cardiomyopathy (TCM) pathophysiology. Patients with disproportionately high catecholamine responses to stressful events are prone to worse clinical outcomes. Catecholamines stimulate platelet activation and, therefore, may determine the clinical presentation and outcomes of TCM. We conducted a retrospective, descriptive study TCM patients admitted between 2003 and 2013 to Einstein Medical Center, Philadelphia, PA, USA and Danbury Hospital, Danbury, CT, USA. A total of 206 patients met Modified Mayo TCM criteria. Using a multiple logistic model,...
Source: Heart and Vessels - August 13, 2015 Category: Cardiology Source Type: research

Effects of blood pressure-lowering on outcome incidence in hypertension: 5. Head-to-head comparisons of various classes of antihypertensive drugs – overview and meta-analyses
Conclusions: The results of all available evidence from head-to-head drug class comparisons do not allow the formulation of a fixed paradigm of drug choice valuable for all hypertensive patients, but the differences found may suggest specific choices in specific conditions, or preferable combinations of drugs.
Source: Journal of Hypertension - June 5, 2015 Category: Cardiology Tags: Reviews Source Type: research

Trends in Antihypertensive Medication Use and Blood Pressure Control Among Adults With Hypertension in Germany.
CONCLUSIONS: Increased and improved antihypertensive use might be a main contributor to the decrease in BP observed in Germany in the last decade. However, there are still socio-demographic and health disparities in hypertension treatment and control. PMID: 25968124 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - May 11, 2015 Category: Cardiology Authors: Sarganas G, Knopf H, Grams D, Neuhauser HK Tags: Am J Hypertens Source Type: research

Lower heart rate in the early postoperative period does not correlate with long-term outcomes after repair of type A acute aortic dissection
Abstract Little evidence exists regarding the need for a reduction in postoperative heart rate after repair of type A acute aortic dissection. This single-center retrospective study was conducted to determine if lower heart rate during the early postoperative phase is associated with improved long-term outcomes after surgery for patients with type A acute aortic dissection. We reviewed 434 patients who underwent aortic repair between 1990 and 2011. Based on the average heart rate on postoperative days 1, 3, 5, and 7, 434 patients were divided into four groups, less than 70, 70–79, 80–89, and greater than ...
Source: Heart and Vessels - May 1, 2015 Category: Cardiology Source Type: research

Abstract 118: Discharge Medications, Hospice Use and 30 Day Outcomes for Hospitalized Heart Failure Patients Session Title: Poster Session I
Conclusions: As heart failure progresses, transfer to palliative or hospice services is often appropriate. Including patients when death is imminent in outcome analyses could overestimate medication effects. Mechanisms for identifying such patients other than hospice use are limited but constitute an important goal for future research.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Stearns, S. C., Rodgers, J. E., Chang, P. P., Sueta, C. A. Tags: Session Title: Poster Session I Source Type: research

Abstract 328: Cardiovascular Disease Associated with Ability to Achieve Renal Transplant and Post-Transplant Adverse Events Session Title: Poster Session III
Conclusions: CVD is common in patients listed for renal transplant. CAD is independently associated with lower odds of receiving a transplant. CAD and rEF are independently associated with increased hazard of post-transplant death or graft failure. Future efforts should focus measures to optimize outcomes in patients with CVD awaiting transplant.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Ismail, S. J., Patel, M., Gindi, R., Salah, A., Tang, I., Benedetti, E., Ardati, A. Tags: Session Title: Poster Session III Source Type: research

HYT-Hypertension in Turkey: A Cross-Sectional Survey on Blood Pressure Control with Calcium Channel Blockers Alone or Combined with Other Antihypertensive Drugs
Conclusions Taken together these findings provide evidence that dihydropyridine-type CCBs, particularly when combined with ACE-inhibitors or angiotensin II receptors blockers, allow to achieve a blood pressure control better than the one reported in the same geographic area by other treatment strategies based on different combinations of diuretics, beta-blockers, ACE-inhibitors, angiotensin II receptors blockers and calcium channel blockers.
Source: High Blood Pressure and Cardiovascular Prevention - April 22, 2015 Category: Cardiology Source Type: research

A Comparison of Vasodilating and Non-vasodilating Beta-Blockers and Their Effects on Cardiometabolic Risk
Abstract Cardiometabolic risk describes a collection of risk factors, with a likely underlying pathophysiology, resulting in accelerated atherosclerosis and the terminal cardiovascular events of myocardial infarction and stroke. Beta-blockers, which are divided as vasodilators or non-vasodilators, are used in the treatment of hypertension and other cardiovascular diseases. Vasodilators have been shown to be of particular benefit in both blood pressure control and other cardiometabolic components with limited disturbance in metabolic parameters. Nebivolol, a third-generation beta-blocker (BB), acts by increasing n...
Source: Current Cardiology Reports - April 21, 2015 Category: Cardiology Source Type: research

Clinical impacts of additive use of olmesartan in hypertensive patients with chronic heart failure: the supplemental benefit of an angiotensin receptor blocker in hypertensive patients with stable heart failure using olmesartan (SUPPORT) trial
This study is registered at clinicaltrials.gov-NCT00417222.
Source: European Heart Journal - April 14, 2015 Category: Cardiology Authors: Sakata, Y., Shiba, N., Takahashi, J., Miyata, S., Nochioka, K., Miura, M., Takada, T., Saga, C., Shinozaki, T., Sugi, M., Nakagawa, M., Sekiguchi, N., Komaru, T., Kato, A., Fukuchi, M., Nozaki, E., Hiramoto, T., Inoue, K., Goto, T., Ohe, M., Tamaki, K., I Tags: Heart failure/cardiomyopathy Source Type: research