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Condition: Heart Failure
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Total 212 results found since Jan 2013.
Association of psoriasis and stroke in end-stage renal disease patients
CONCLUSIONS: Contrary to prior research in the general population, psoriasis in ESRD patients was not associated with the risk of stroke after controlling for various demographic and clinical parameters. Our finding emphasizes the importance of controlling for a variety of factors in population studies examining associations of diseases and risk factors.PMID:37716600 | DOI:10.1016/j.amjms.2023.09.014
Source: The American Journal of the Medical Sciences - September 16, 2023 Category: General Medicine Authors: Naomi Siddiquee Jennifer L Waller Stephanie L Baer Azeem Mohammed Sarah Tran Sandeep Padala Lufei Young Mufaddal Kheda Wendy B Bollag Source Type: research
McConnell ’ s Bid to Downplay Freezes Undermined by History of Politicians Lying About Their Health
After Senate Minority Leader Mitch McConnell froze during a press conference this month, the Kentucky Republican’s second such episode this summer, his office released a note from the Capitol physician intended to calm those worried about his ability to continue at his job.
Dr. Brian Monahan told McConnell in the letter that there was “no evidence that you have a seizure disorder or that you experienced a stroke, TIA or movement disorder such as Parkinson’s disease.” Monahan suggested the episodes may be related to the Leader’s concussion in March or to dehydration.
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Source: TIME: Health - September 11, 2023 Category: Consumer Health News Authors: Mini Racker Tags: Uncategorized Congress Source Type: news
Roche and Alnylam report positive topline results from Phase 2 study KARDIA-1 of zilebesiran, an investigational RNAi therapeutic in development to treat hypertension in patients at high risk of cardiovascular disease
Zilebesiran met primary endpoint demonstrating greater than 15 mmHg reduction of systolic blood pressure at three months of treatment compared to placeboStudy met key secondary endpoints showing consistent and sustained reductions of systolic blood pressure at six monthsZilebesiran demonstrated an encouraging safety and tolerability profile in adult patients with mild-to-moderate hypertensionFull study results to be presented at an upcoming scientific conferenceBasel, 7 September 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) and Alnylam announced today that the Phase 2 study KARDIA-1 of zilebesiran, an investigational RNAi the...
Source: Roche Media News - September 7, 2023 Category: Pharmaceuticals Source Type: news
Trends in cardiovascular complications of pregnancy: A nationwide inpatient sample analysis
CONCLUSION: There are concerning increases in certain cardiac complications during pregnancy. This is likely due to increasing age at the time of pregnancy and associated comorbidities.PMID:37678669 | DOI:10.1016/j.amjms.2023.09.001
Source: The American Journal of the Medical Sciences - September 7, 2023 Category: General Medicine Authors: Eric D Warner Saaniya Farhan Matthew Bierowski Farhan Sahawneh Estefania Oliveros Preethi Pirlamarla Stefanie Marek-Iannucci Bhavadharini Ramu Waqas Ullah Yevgeniy Brailovsky Indranee N Rajapreyar Source Type: research
Trends in cardiovascular complications of pregnancy: A Nationwide Inpatient Sample analysis: Trends in cardiovascular complications of pregnancy
CONCLUSION: There are concerning increases in certain cardiac complications during pregnancy. This is likely due to increasing age at the time of pregnancy and associated comorbidities.PMID:37678669 | DOI:10.1016/j.amjms.2023.09.001
Source: The American Journal of the Medical Sciences - September 7, 2023 Category: General Medicine Authors: Eric D Warner Saaniya Farhan Matthew Bierowski Farhan Sahawneh Estefania Oliveros Preethi Pirlamarla Stefanie Marek-Iannucci Bhavadharini Ramu Waqas Ullah Yevgeniy Brailovsky Indranee N Rajapreyar Source Type: research
To support the use of NT-proBNP to better detect heart failure in patients with type 2 diabetes
ConclusionThese determinants might contribute to investigate the NT-proBNP in T2DM sufferers. A decision support system to appropriately ease the prescription of NT-proBNP might be therefore implemented in primary care settings.
Source: Endocrine - August 29, 2023 Category: Endocrinology Source Type: research
Cardiovascular Complications in Pregnancy
AbstractPurpose of reviewWe review the epidemiology, risk factors, presentation, pathophysiology, diagnosis, peripartum management, and postpartum follow-up of chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.Recent findingsWe discuss pathophysiology and evidence-based management for chronic hypertension, hyperlipidemia, acute myocardial infarction, stroke, heart failure, pulmonary embolism, and atrial fibrillation.SummaryIt is essential for providers and patients to understand how cardiovascular diseases cause complications in pregnancy a...
Source: Current Treatment Options in Cardiovascular Medicine - August 25, 2023 Category: Cardiology Source Type: research
Sestrin2 as a Potential Target in Hypertension
Diagnostics (Basel). 2023 Jul 14;13(14):2374. doi: 10.3390/diagnostics13142374.ABSTRACTHypertension is a highly complex, intricate condition affecting millions of individuals across the globe. Nearly half of adults in the United States are diagnosed with hypertension, with incident rates projected to rise over the next decade. Hypertension is a precursor to many cardiovascular diseases including atherosclerosis, stroke, myocardial infarction, heart failure, and peripheral artery disease. This review describes the major processes contributing to the development of hypertension and how Sestrin2 (Sesn2), an antioxidative prot...
Source: Atherosclerosis - July 29, 2023 Category: Cardiology Authors: Steven Didik Hao Wang Adewale Segun James Lily Slotabec Ji Li Source Type: research
Global Economic Burden Associated with Chronic Kidney Disease: A Pragmatic Review of Medical Costs for the Inside CKD Research Programme
CONCLUSION: Globally, CKD carries a significant economic burden, which increases substantially with increasing disease severity. We identified significant gaps in published costs and inconsistent costing definitions. Cost-effective interventions that target primary prevention and disease progression are essential to reduce CKD burden. Our results can be used to guide cost collection and facilitate better comparisons across countries/regions to inform healthcare policy.PMID:37493856 | DOI:10.1007/s12325-023-02608-9
Source: Adv Data - July 26, 2023 Category: Epidemiology Authors: Vivekanand Jha Saeed M G Al-Ghamdi Guisen Li Mai-Szu Wu Panagiotis Stafylas Lise Retat Joshua Card-Gowers Salvatore Barone Claudia Cabrera Juan Jose Garcia Sanchez Source Type: research
Roche enters partnership with Alnylam to co-develop and co-commercialise RNAi therapeutic zilebesiran to treat hypertension in patients with high cardiovascular risk
Partnership combines Roche ’s proven track record of successfully developing and launching innovative medicines worldwide withAlnylam ’s leadership in RNAi therapeuticsZilebesiran, a Phase 2 RNAi therapeutic, has best-in-disease potential for patients with hypertension at high risk of cardiovascular morbidity and mortality, by robustly and durably lowering blood pressureHypertension, the leading cause of cardiovascular disease, affects more than 1.2 billion adults worldwide. While several therapies exist, a significant unmet need, especially for high risk patients, remains.1Basel, 24 July 2023 - Roche (SIX: RO, ROG; OT...
Source: Roche Media News - July 24, 2023 Category: Pharmaceuticals Source Type: news
