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Total 131 results found since Jan 2013.

Early outcomes of patients transferred with ruptured suprarenal aneurysm or dissection.
Conclusions Although the number of patients with rSRAD is low and those who are transferred alive are a self-selecting group, this study suggests that transfer of such patients to a specialist vascular centre is associated with acceptable mortality rates following emergency complex aortic repair. PMID: 29484940 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - February 27, 2018 Category: Surgery Authors: Rudarakanchana N, Hamady M, Harris S, Afify E, Gibbs R, Bicknell CD, Jenkins MP Tags: Ann R Coll Surg Engl Source Type: research

Impact of intracranial artery calcification on cerebral hemodynamic changes
ConclusionHeavier IAC might cause generalized artery flow velocity changes and increased pulsatility index, which may indicate high resistance within cerebrovasculature.
Source: Neuroradiology - February 9, 2018 Category: Radiology Source Type: research

Ticagrelor for Secondary Prevention of Atherothrombotic Events After Myocardial Infarction: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
AbstractThe National Institute for Health and Care Excellence (NICE) invited AstraZeneca, the manufacturer of ticagrelor (Brilique®), to submit evidence on the clinical and cost effectiveness of ticagrelor 60  mg twice daily (BID) in combination with low-dose aspirin [acetylsalicylic acid (ASA)] compared with ASA only for secondary prevention of atherothrombotic events in patients with a history of myocardial infarction (MI) and who are at increased risk of atherothrombotic events. Kleijnen Systematic R eviews Ltd (KSR), in collaboration with Maastricht University Medical Centre+, was commissioned as the evidence review ...
Source: PharmacoEconomics - January 18, 2018 Category: Health Management Source Type: research

Rising to the Challenge: Stroke care received between April 2016 to March 2017 The Fourth SSNAP Annual Report
The report highlights the improvements made in stroke care in England, Wales and Northern Ireland over the past four years. Using real world quality improvement case studies, it outlines the different approaches taken by local teams to improve their stroke services across the patient pathway; what was the challenge faced? What was the solution? What impact did the QI project have on care processes? The report also offers practical tips and recommendations on how other clinical teams could adapt similar QI approaches to improve the care provided to their patients in the future.
Source: Current Awareness Service for Health (CASH) - December 8, 2017 Category: Consumer Health News Source Type: news

Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research

Risk factors for falls among older Aboriginal and Torres Strait Islander people in urban and regional communities.
CONCLUSION: Falls were experienced by one-quarter of study participants. Fall risk factors identified for older Aboriginal people appear to be similar to those identified in the general population. Understanding of fall risk factors may assist with the development of appropriate and effective community-led fall prevention programs. PMID: 29143435 [PubMed - as supplied by publisher]
Source: Australasian Journal on Ageing - November 15, 2017 Category: Geriatrics Authors: Lukaszyk C, Radford K, Delbaere K, Ivers R, Rogers K, Sherrington C, Tiedemann A, Coombes J, Daylight G, Draper B, Broe T Tags: Australas J Ageing Source Type: research

Risk factors for falls among older Aboriginal and Torres Strait Islander people in urban and regional communities
ConclusionFalls were experienced by one‐quarter of study participants. Fall risk factors identified for older Aboriginal people appear to be similar to those identified in the general population. Understanding of fall risk factors may assist with the development of appropriate and effective community‐led fall prevention programs.
Source: Australasian Journal on Ageing - November 15, 2017 Category: Geriatrics Authors: Caroline Lukaszyk, Kylie Radford, Kim Delbaere, Rebecca Ivers, Kris Rogers, Catherine Sherrington, Anne Tiedemann, Julieann Coombes, Gail Daylight, Brian Draper, Tony Broe Tags: Research Article Source Type: research

Sight Impairment registration due to stroke —A small yet significant rise?
ConclusionsThese data suggest a small but statistically significant increase in the incidence of certifiable visual impairment due to stroke between 2008 and 2014. Figures are, however, considerably lower than estimated, perhaps suggesting that more should be done to address the visual needs of those who have suffered stroke. In the United Kingdom, there was a significant increase in the incidence of certifiable visual impairment due to stroke between 2008 and 2014. Figures are, however, considerably lower than estimated, perhaps suggesting that more should be done to address the visual needs of those who have suffered stroke.
Source: Brain and Behavior - October 29, 2017 Category: Neurology Authors: Catey Bunce, Antra Zekite, Richard Wormald, Fiona Rowe Tags: ORIGINAL RESEARCH Source Type: research

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Conclusion: There is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424 Received: 17 December 2015 Revised: 12 August 2016 Accepted: 30 August 2016 Published: 10 October 2017 Address correspondence to V. Stone, School of Life Sciences, Heriot-Watt University, Edinburgh, UK. Telephone: +44 131 451 3460. Email: v.stone@hw.ac.uk V.S. currently receives grant funding from Byk Altana and from The European Ceramic Fibre Industry Association (ECFIA). In the past, V.S. has received funding from Unilever and GlaxoSmithKline....
Source: EHP Research - October 10, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

130 Improving the implementation of anti-coagulation therapy in AF patients at risk of stroke in a primary care setting
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia of the heart and is of increasing prevalence1. There are strong implications of increased stroke risk in AF patients2. In particular, AF related stroke carries a near 50% risk of persisting disability and directly increases costs for treatment by over a third in comparison with non AF stroke patients3,4. As an estimated contributing cause of 15-20% of all strokes, the economic and societal impact of AF is of extreme importance5. To monitor how efficiently stroke prevention is implemented in a primary care setting we will identify those ‘at risk...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

Stroke patients in Wales ‘could die’ because thrombectomy not available
Acute shortage in NHS of specialist doctors who undertake life-saving treatment means hospitals cannot provide itStroke patients in Wales are being denied a life-saving pioneering treatment after the surgical team providing it had to be mothballed because of an acute NHS shortage of the specialist doctors who undertake the procedure.Internal NHS emails obtained by the Guardian reveal that health service bosses in Wales are pleading with hospitals in England to perform mechanical thrombectomy on their patients to save them from disability and death.Continue reading...
Source: Guardian Unlimited Science - October 1, 2017 Category: Science Authors: Denis Campbell Health policy editor Tags: Stroke NHS Wales Health Medical research Society Doctors Science UK news Source Type: news

A Novel Atrial Fibrillation Evaluation Modelling Solution For NHS
Approximately every fifth stroke in UK is due to AF and costs the UK National Health Service are between $12,000 and $17,500 per stroke. The aim of this study was to undertake a retrospective health economic analysis of the cost-effectiveness and implications related to opportunistic Atrial Fibrillation (AF) screening in primary care and the detection of previously undiagnosed AF cases in patients, and create a novel modelling solution that can empower individual users and organisations in England, Wales and Northern Ireland in their decision making, technology assessment, comparison of various anticoagulation d rug group...
Source: Value in Health - October 1, 2017 Category: International Medicine & Public Health Authors: G Xydopoulos, R Fordham, Z Khanbai Source Type: research

Coronary Perforation Complicating Percutaneous Coronary Intervention in Patients With a History of Coronary Artery Bypass Surgery: An Analysis of 309 Perforation Cases From the British Cardiovascular Intervention Society Database Coronary Interventions
Conclusions— CP is an infrequent event during PCI-CABG but is closely associated with adverse clinical outcomes. A legacy effect of perforation on 12-month mortality was observed.
Source: Circulation: Cardiovascular Interventions - September 15, 2017 Category: Cardiology Authors: Kinnaird, T., Anderson, R., Ossei-Gerning, N., Cockburn, J., Sirker, A., Ludman, P., de Belder, M., Johnson, T. W., Copt, S., Zaman, A., Mamas, M. A., on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascul Tags: Percutaneous Coronary Intervention, Stent, Treatment Coronary Interventions Source Type: research