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Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression
Conclusions Stroke comprises ischemic stroke and ICH. The immuno-inflammatory process is involved in neural plasticity following events such as a hemorrhage or ischemic stroke. After ischemia, astrocytes, microglia, and MDMs play important roles during rehabilitation with the modulation of cytokines or chemokines, such as TNF-α and IL-1. Moreover, MiRNAs are also important posttranscriptional regulators in these glial mitochondrial responses to cerebral ischemia. ICH involves processes similar and different to those seen in ischemia, including neuronal injury, astrocytic and microglial/macrophage activation, and n...
Source: Frontiers in Psychiatry - April 10, 2019 Category: Psychiatry Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

Call for human contact and support: an interview study exploring patients' experiences with inpatient stroke rehabilitation and their perception of nurses' and nurse assistants' roles and functions.
CONCLUSION: The findings deepen our understanding of how patients experience inpatient rehabilitation. The patients struggled with existential thoughts and concerns about the future and therefore called for human contact and support from the nursing staff. They perceived the nursing staff as mostly polite and helpful, but were unclear about the nursing staff's function in rehabilitation which, in the patients' perspective, equals physical training. Implications for Rehabilitation Nursing staff need to pay attention to the patients' needs, existential thoughts and concerns during inpatient rehabilitation. Meaningful goals f...
Source: Disability and Rehabilitation - October 24, 2017 Category: Rehabilitation Authors: Loft MI, Martinsen Woythal B, Esbensen BA, Mathiesen LL, Iversen HK, Poulsen I Tags: Disabil Rehabil Source Type: research

Supporting the Women in our Lives: Stroke Prevention
May is Stroke Awareness Month and May 10-16th is National Women's Health Week, making this the perfect time to talk about the special challenges women face related to stroke and how women can reduce their risk and protect their health. Being the mid-Atlantic Regional Health Administrator might make stroke prevention my professional duty, but it's my role as a father, husband, and son to so many special women that makes it my personal responsibility. It's alarming to think that every 4 minutes someone in the United States dies of a stroke -- most of them women. Stroke -- which is sometimes called a brain attack -- happens...
Source: Healthy Living - The Huffington Post - May 18, 2015 Category: Consumer Health News Source Type: news