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Condition: Atrial Fibrillation
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Total 397 results found since Jan 2013.

Adherence to oral anticoagulation in ischemic stroke patients with atrial fibrillation
CONCLUSIONS: Adherence was poor in half of AF patients who survived an ischaemic stroke. Independent patient-related factors, rather than composite scores, were associated with poor adherence in these patients.KEY MESSAGESAdherence was poor in half of the atrial fibrillation patients who survived an ischaemic stroke.Independent patient-related factors rather than composite scores were associated with poor adherence.The findings support the importance of recognising adherence support as a crucial part of holistic patient care recommended by recent AF guideline.PMID:34498537 | DOI:10.1080/07853890.2021.1968031
Source: Annals of Medicine - September 9, 2021 Category: Internal Medicine Authors: Paula Tiili Ioannis Leventis Janne Kinnunen Ida Svedjeb äck Mika Lehto Efstathia Karagkiozi Dimitrios Sagris George Ntaios Jukka Putaala Source Type: research

Importance of attributes and willingness to pay for oral anticoagulant therapy in patients with atrial fibrillation in China: A discrete choice experiment
by Jiaxi Zhao, Hao Wang, Xue Li, Yang Hu, Vincent K. C. Yan, Carlos K. H. Wong, Yutao Guo, Marco K. H. Cheung, Gregory Y. H. Lip, Chung-Wah Siu, Hung-Fat Tse, Esther W. Chan BackgroundAdherence to oral anticoagulant therapy in patients with atrial fibrillation (AF) in China is low. Patient preference, one of the main reasons for discontinuation of oral anticoagulant therapy, is an unfamiliar concept in China. Methods and findingsA discrete choice experiment (DCE) was conducted to quantify patient preference on 7 attributes of oral anticoagulant therapy: antidote (yes/no), food –drug interaction (yes/no), frequency of blo...
Source: PLoS Medicine - August 26, 2021 Category: Internal Medicine Authors: Jiaxi Zhao Source Type: research

FDA Approves Expanded Peripheral Artery Disease (PAD) Indication for XARELTO ® (rivaroxaban) Plus Aspirin to Include Patients After Lower-Extremity Revascularization (LER) Due to Symptomatic PAD
RARITAN, N.J., August 24, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved an expanded peripheral artery disease (PAD) indication for the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) to include patients following recent lower-extremity revascularization (LER) due to symptomatic PAD. The approval is based on data from the Phase 3 VOYAGER PAD study. With this approval, XARELTO® is the first and only therapy indicated to help reduce the risks of major cardiovascular (CV) events in p...
Source: Johnson and Johnson - August 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study
Discussion: Our findings indicate that a focal stroke lesion might be related to pathophysiological processes leading to global cognitive impairment. The poorer prognosis of PSCI in patients with vascular risk factors emphasizes the need for further research on complex vascular risk factor interventions to prevent PSCI.
Source: Frontiers in Neurology - August 5, 2021 Category: Neurology Source Type: research

Global cognitive performance at 4-year follow-up in individuals with atrial fibrillation —findings from The Irish Longitudinal Study on Ageing
ConclusionIndividuals with AF were more likely to show an increase in rate of errors between waves 1 and 3 (4-year follow-up period) in the TILDA population; however, results were not significant when controlling for age, sex and level of education.
Source: Age and Ageing - July 21, 2021 Category: Geriatrics Source Type: research

Stroke management in a Swiss community hospital - in close collaboration with a stroke centre
CONCLUSION: Our findings support further education of the population in recognition of stroke symptoms and assessment of cardiovascular risk factors according to guidelines. Telemedical cooperation with a local stroke centre can result in adequate quality of care in these patients.PMID:34098584 | DOI:10.4414/smw.2021.20490
Source: Swiss Medical Weekly - June 7, 2021 Category: General Medicine Authors: Rolf Erlebach Esther B ächli Esther Gerrits Mich èle Hess Source Type: research

Impact of the COVID-19 lockdown on the adherence of stroke patients to direct oral anticoagulants: a secondary analysis from the MAAESTRO study
ConclusionOur data suggest that a major disruption of social life (i.e., the imposed COVID-19 lockdown) is unlikely to relevantly affect the medication intake behaviour of patients with high pre-established adherence, but might have an impact in patients with previously suboptimal adherence.Trial registration numberMAAESTRO: electronic Monitoring and improvement of Adherence to direct oral Anticoagulant treatment —a randomized crossover study of an Educational and reminder-based intervention in ischaemic STROke patients under polypharmacy, NCT03344146.
Source: Journal of Neurology - June 3, 2021 Category: Neurology Source Type: research

Direct oral anticoagulants and therapeutic adherence: do not let your guard down
CONCLUSIONS: Polypharmacy, patient's isolation, such as a low education level were statistically associated with a low therapeutic adherence. Therapeutic adherence remains an unsolved problem for anticoagulated patient. To identify patients at higher risk of poor compliance and therapeutic failure and establish targeted care pathways is a priority.PMID:33896375 | DOI:10.1080/00015385.2021.1908702
Source: Acta Cardiologica - April 26, 2021 Category: Cardiology Authors: Leonardo Di Gennaro Martina Monaco Claudia Riccio Erica De Candia Maria Adele Alberelli Cinzia di Martino Maria Basso Maria Antonietta Ferretti Stefano Lancellotti Raimondo De Cristofaro Source Type: research

SUPPORT ‐AF III: supporting use of AC through provider prompting about oral anticoagulation therapy for AF
AbstractOnly half of atrial fibrillation (AF) patients with elevated stroke risk receive anticoagulation (AC). Electronic health record (EHR) alerts have the potential to close the gap. We designed an outpatient EHR alert (linked to an order set for ordering AC, labs, and specialty referrals) that fired when cardiology and primary care providers (PCPs) saw AF patients not on AC. We assigned all untreated patients seen by cardiology providers and PCPs in the 8  months before and after the alert launch to pre- and post-launch intervention cohorts, respectively. Untreated AF patients seeing other types of providers became co...
Source: Journal of Thrombosis and Thrombolysis - March 10, 2021 Category: Hematology Source Type: research

Health-related quality of life after ischemic stroke: impact of sociodemographic and clinical factors
CONCLUSION: Stroke survivors have significantly reduced HR-QoL. Multiple interacting factors are associated with an unfavorable outcome after IS. Early detection of these factors would help to improve the care for IS patients, to reduce disabilities and improve HR-QoL.PMID:33637026 | DOI:10.1080/01616412.2021.1893563
Source: Neurological Research - February 27, 2021 Category: Neurology Authors: M Tsalta-Mladenov S Andonova Source Type: research