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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

P74 Keep it simple: MAC (Manual Aspiration with Contrast) technique for the endovascular management of acute ischemic stroke (LVO & MVO)
We report a prospectively collected clinical experience with a simple technique: MAC (Manual Aspiration Contrast Enhancement) as the primary method for vessel recanalization.Gently contrast injection while the aspiration catheter is advancedto the thrombus and subsequentlycreating a closed-loop system with the contrast column within the cathetercan result in better visualization during the aspiration, thus improving the FPEavoiding clot fragmentation, multiple passes and blind movements of catheter by a single operator.Methods47 prospectively patients with ELVO and 3 cases of middle vessel occlusion (MVO) at four instituti...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Pabon, B., Torres, V., Patino, M., Pelaez, F., Mutis, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P76 Fate of incomplete reperfusion caused by multiple small occlusions or slow flow in eTICI 2b reperfusion grade: insights from the ESCAPE-NA1 trial
ConclusionThe majority of incomplete reperfusion caused by multiple small occlusions or slow flow was associated with new infarction on follow-up imaging. In half of these cases, distal occlusions (meniscus sign) were detected, which could be potential targets for intra-arterial thrombolysis.ReferencesKaesmacher J, Ospel JM, Meinel TR, et al. Thrombolysis un Cerebral Infarction 2b Reperfusions. Stroke. September 2020. Do you have any conflict of interest to declare?: No
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Cimflova, P., Singh, N., Kappelhof, M., Sehgal, A., Ospel, J., Bala, F., Almekhlafi, M., Tymianski, M., Hill, M., Goyal, M. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P81 Novel synthetic clot analogs for in-vitro stroke modelling
ConclusionSelected synthetic clots can successfully be implemented in an in-vitro training environment of mechanical thrombectomy. The clots’ different properties might serve to mimic fibrin-rich and red blood cell human thrombi.ReferencesNadine Wortmann, Thomas Andersek, Helena Guerreiro, et al. Development of Synthetic Thrombus Models to Simulate Stroke Treatment in a Physical Neurointerventional Training Model, All Life 2022;15:1, 283–301, DOI:10.1080/26895293.2022.2046181Spallek J, Kuhl J, Wortmann N, et al. Design for Mass Adaptation of the Neurointerventional Training Model Hannes with Patient-specific An...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guerreiro, H., Wortmann, N., Andersek, T., Ngo, T., Frölich, A., Krause, D., Fiehler, J., Kyselyova, A., Flottmann, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P83 The relationship of functional outcome after mechanical thrombectomy and serum glucose is partially mediated by edema formation
ConclusionEdema formation explains 15% of the total adverse effects of high blood glucose levels. Major pathways might include other direct effects of high blood glucose, such as altered vessel wall and thrombus characteristics and higher thrombogenicity of the cerebral blood flow.ReferencesThorén, M., et al. "Predictors for Cerebral Edema in Acute Ischemic Stroke Treated with Intravenous Thrombolysis." Stroke 2017;48(9): 2464–2471. Do you have any conflict of interest to declare?: YesConflict of Interest StatementHelge Kniep is a consultant for Eppdata.Jens Fiehler received research support from: German Minis...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Kniep, H., Meyer, L., Bechstein, M., Hanning, U., Fiehler, J., Broocks, G. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P89 "Not only Carotid: two unusual cases of treatment of steno-obstructions
ConclusionsThe persistence of fetal anastomosis between carotid and basilar artery would represent a posterior cerebral circulation risk for ischemia and embolic infarction; in these cases the menagement of carotid steno-obstructions is challenging and requires special considerations.ReferencesJin X, Sun L, Feng Z, Li X, et. al. Persistent Hypoglossal Artery as a Potential Risk Factor for Simultaneous Carotid and Vertebrobasilar Infarcts. Front Neurol. 2018 Oct 11;9:837.Burgard M, Psathas E, Mordasini P, et. al. Symptomatic Internal Carotid Artery Stenosis in the Presence of a Persistent Primary Hypoglossal Artery. Vascula...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Corraine, S., Ledda, V., Schirru, F., Erta, M., Ferrari, A., Fusaro, F., Comelli, S. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

200 Covid-19 and acute ischaemic strokes in CADASIL: a systematic review of the literature
Conclusions This systematic review describes the pattern of COVID-19 associated AIS in CADASIL. Such multiple infarcts, primarily affecting the internal borderzones, have been described in patients with Covid-19 without CADASIL. We discuss possible pathophysiological mechanisms, which may be extrapolated to patients with cerebral small vessel disease, including endothelial injury causing microvascular thrombosis and hypoperfusion due to cerebral blood flow dysautoregulation.
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 12, 2022 Category: Neurosurgery Authors: Noui, Y., Williams, O., Chan, N., Chandra, J., Sztriha, L. Tags: Poster presentations Source Type: research

Cerebral venous thrombosis after COVID-19 vaccination: the role for endovascular treatment
Cerebral venous thrombosis (CVT) is a unique cause of stroke. Population-based studies demonstrate an incidence of clinically significant CVT of 1.3–1.5 per 100 000 per year.1 2 This may be an underestimated incidence, as these studies were not based on review of imaging and the often benign nature of this entity may lead to underdiagnoses. In the JNIS paper published by Cleaver et al,3 the authors describe their experience with endovascular treatment (EVT) in patients with cerebral venous sinus thrombosis in patients following COVID-19 vaccination. CVT-related stroke primarily affects young adult and middle-aged pat...
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Mahajan, A., Hirsch, J. A. Tags: COVID-19 Commentary Source Type: research

Efficacy of combined use of a stent retriever and aspiration catheter in mechanical thrombectomy for acute ischemic stroke
Conclusions SCBT increases the SRFP rate and shortens the puncture-to-reperfusion time without increasing procedural complications.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Okuda, T., Arimura, K., Matsuo, R., Tokunaga, S., Hara, K., Yamaguchi, S., Yoshida, H., Kurogi, R., Kameda, K., Ito, O., Tsumoto, T., Iihara, K., Mizokami, T., Uwatoko, T., Nishimura, A., Iwaki, K., Mizoguchi, M., QNET investigators Tags: Ischemic stroke Source Type: research

O-012 Peri-procedural complications, clinical outcomes and recurrence/retreatment rates after endovascular versus surgical treatment of intracranial aneurysms: a real-world assessment from the NVQI-QOD cerebral aneurysm registry
ConclusionEndovascular treatment of intracranial aneurysms was associated with better overall clinical outcomes than surgical clipping with improved disability free survival and better disposition at discharge or follow-up, across both ruptured and unruptured aneurysms. Although intraoperative complications were higher for ruptured aneurysms treated with endovascular treatment, there was no difference in unruptured aneurysms versus surgical clipping. Post-operative complications were lower for the endovascular cohort regardless of presentation. Overall, these data support ongoing primary adoption of endovascular treatment ...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Bauknight, W., Noorani, S., Abdalla, R., Tejada, J., Church, E., Sahlein, D., Howington, J., Ansari, S. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-019 Initial clinical experience with a novel mechanical thrombectomy device-the thrombX retriever
ConclusionThis preliminary study suggests the ThrombX Retriever is safe and has a high rate of substantial reperfusion. A larger prospective trial to assess the device effectiveness is planned.Disclosures D. Behme: 2; C; Thromb X Medical, Phenox, Penumbra, Balt, Vesalio, Acandis. M. Wiesmann: 1; C; Stryker Neurovascular. 2; C; Stryker Neurovascular. 6; C; AB Medica, Acandis, Cerenovus, Kaneka Pharmaceuticals, Medtronic, Mentice AB, Phenox, Philips Healthcare, Stryker Neurovascular. O. Nikoubashman: 1; C; Stryker Neurovascular. 6; C; Phenox, Stryker Neurovascular. H. Ridwan: 2; C; ThrombX Medical. D. Hassan: None. T. Liebig...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Behme, D., Wiesmann, M., Nikoubashman, O., Ridwan, H., Hassan, D., Liebig, T., Trumm, C., Holtmannspötter, M., Marks, M., Szikora, I. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-020 The tigertriever 13 distals study: distal ischemic stroke treatment with adjustable low-profile stentriever
ConclusionThe TIGERTRIEVER 13 device with operator controllability and high fluoroscopy visibility and its small size can potentially provide a safe and effective clot removal in patients with distal vessels occlusion.Disclosures D. Fiorella: 1; C; Rapid Medical. R. Gupta: None. R. Chapot: None. J. Saver: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fiorella, D., Gupta, R., Chapot, R., Saver, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-052 The pennsylvania post-market multicenter experience with flow re-direction endoluminal device (FRED)
ConclusionThe results of the early post-market experience with the FRED device show reasonable safety and adequate aneurysmal occlusion rates comparable to other flow diverters. However, more extensive multicenter studies with more extended follow-up data are needed to assess the long-term safety and durability of the device.Abstract O-052 Table 1Baseline descriptive statistics Number of patients n=61 Gender Male 11 (18%) Female 50 (82%) Age (Years: median; IQR) 58 (51 – 68) Multiple Intracranial Aneurysms 21 (34.4%) Family history of aneurysms 9 (14.8%) Smoking History Never smokers 26 (42.6%) Past smokers 13 (21.3...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Salem, M., Kvint, S., Hendrix, P., Al Saiegh, F., Gajjar, A., Goren, O., Gross, B., Jabbour, P., Lang, M., Schirmer, C., Tjoumakaris, S., Griessenauer, C., Burkhardt, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-061 Predictors of failed mechanical thrombectomy for large vessel occlusion: insights from the stroke thrombectomy and aneurysm registry (STAR)
ConclusionIn one of the largest studies to evaluate factors associated with failure MT in real world practice, we demonstrate that MTF is associated with significantly more complications and worse outcome. Final use of aspiration and rescue intracranial stenting may increase chances of recanalization.Disclosures M. Webb: None. M. Essibayi: None. S. Al Kasab: None. I. Maier: None. M. Psychogios: None. A. Alawieh: None. S. Wolfe: None. A. Arthur: None. T. Dumont: None. P. Kan: None. J. Kim: None. R. De Leacy: None. J. Osbun: None. A. Rai: None. P. Jabbour: None. M. Park: None. R. Crosa: None. M. Levitt: None. A. Polifka: Non...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Webb, M., Essibayi, M., Al Kasab, S., Maier, I., Psychogios, M., Alawieh, A., Wolfe, S., Arthur, A., Dumont, T., Kan, P., Kim, J., De Leacy, R., Osbun, J., Rai, A., Jabbour, P., Park, M., Crosa, R., Levitt, M., Polifka, A., Casagrande, W., Yoshimura, S., Tags: SNIS 19th annual meeting oral abstracts Source Type: research

O-066 Actin imparts thrombolysis resistance in acute ischemic stroke clots - gelsolin accelerates TPA mediated thrombolysis
ConclusionActin is one of the major structural components of AIS clots and could be responsible for fibrinolytic resistance. Targeting actin molecules would positively impact improving the outcome of recanalization of LVO-AIS.Abstract O-066 Figure 1Disclosures S. Arul: None. D. Dai: None. O. Mereuta: None. S. Ghozy: None. W. Brinjikji: None. D. Kallmes: None. R. Kadirvel: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Arul, S., Dai, D., Mereuta, O., Ghozy, S., Brinjikji, W., Kallmes, D., Kadirvel, R. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-001 Evaluation of cerebrovascular flow parameters relative to guide catheter position during acute ischemic stroke treatment
ConclusionDramatically reduced MCA flow can significantly reduce downstream migration of thrombus during thrombectomy. This study demonstrates that Zoom 88 positioned distal to the PComm achieved similar rates of flow control as balloon guide catheters inflated in the proximal ICA. In all cases, flow compensation within the CoW affected the outflow rates of the ipsilateral and contralateral ACA branches, posterior cerebral arteries, and contralateral MCA.Abstract P-001 Figure 1Disclosures H. Berns: 5; C; Northern Arizona University. O. Fisher: 5; C; Northern Arizona University. B. Fennell: 5; C; Northern Arizona University...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Berns, H., Fisher, O., Fennell, B., Ponugupaty, A., Merritt, W., Ducruet, A., Becker, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research