O-066 Actin imparts thrombolysis resistance in acute ischemic stroke clots - gelsolin accelerates TPA mediated thrombolysis

ConclusionActin is one of the major structural components of AIS clots and could be responsible for fibrinolytic resistance. Targeting actin molecules would positively impact improving the outcome of recanalization of LVO-AIS.Abstract O-066 Figure 1Disclosures S. Arul: None. D. Dai: None. O. Mereuta: None. S. Ghozy: None. W. Brinjikji: None. D. Kallmes: None. R. Kadirvel: None.

Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Arul, S., Dai, D., Mereuta, O., Ghozy, S., Brinjikji, W., Kallmes, D., Kadirvel, R. Tags: SNIS 19th annual meeting oral abstracts Source Type: research