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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

EP59 Successful mechanical thrombectomy after microsurgical clipping of a ruptured middle cerebral artery aneurysm
We report about a 62 year old woman who was brought to the emergency room after being found down at home. On admission she was somnolent but accessible with mild focal neurological deficits. A computed tomography of the brain revealed a right temporal hematoma with subarachnoid and intraventricular hemorrhage due to a ruptured saccular aneurysm of the MCA trifurcation. A surgical approach was considered best treatment option and microsurgical clipping was performed. Intraoperative microvascular Doppler depicted a spontaneous thrombus formation in M1-Segment and the patient was transferred to the angio-suite for a mechanica...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Boutchakova-Meyer, M., Beyaz, P., Roth, C., Papanagiotou, P. Tags: Treatment Source Type: research

EP63 The TAPAS study: thrombectomy aspiration post-market study in acute stroke
ConclusionThe Q Catheter showed good deliverability and revascularization rates in this real-world setting with no safety concerns.ReferenceLong TD, Kallmes DF, Hanel R, Shigematsu T, Halaszyn AM, Wolter J, Berenstein A. Novel aspiration catheter design for acute stroke thrombectomy. J Neurointerv Surg 2019 Feb;11(2):190–195.DisclosureConsultant MIVI Neuroscience, Inc.
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Ballenilla Marco, F., Espinosa, M., Zamarro, J., Masso, J., Garmendia, E., Pumar, J., Larrea, J., Mosqueira, A. Tags: Treatment Source Type: research

EP65 Mechanical thrombectomies, initial experiences from Kosovo Case series presentation
ConclusionEndovascular treatment has proven to be safe and efficacious for AIS. Our patients recovered and were discharged within 7–11 days after ictus.mRS after 90 days 0 at two (male) patients,mRS 1 at two patients and one patient is mRS 3.These case series demonstrate the clinical efficacy, safety, and favorable clinical outcome of first mechanical thrombectomies performed in Kosovo.ReferencesHeider D, Simgen A, Wagenpfeil G, et al. Why we fail: mechanisms and co-factors of unsuccessful thrombectomy in acute ischemic stroke. Neurological Sciences 2020.Meyer L, Alexandrou M, Leischner H, Flottmann F, Deb-Chatterji ...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Gjikolli, B., Kalousek, V., Culo, B., Murati, M., Bejta, I., Shatri, J., Shala, N., Dedushi, K., Jashari, F., Pasha, F., Komoni, E., Boshnjaku, D., Myftiu, B., Jaha, L., Kuci, A., Miftari, R., Govori, V., Bulja, D., Vegar, S. Tags: Treatment Source Type: research

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Conclusions An assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in contrast to atrium appendage low blood flow retaining high thrombin levels.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Itsekson Hayosh, Z., Abu Bandora, E., Shelestovich, N., Nulman, M., Bakon, M., Yaniv, G., Khaitovitch, B., Balan, S., Gerasimova, A., Drori, T., Mausbach, S., Schwammenthal, Y., Afek, A., Chapman, J., Shavit Stein, E., Orion, D. Tags: Ischemic stroke Source Type: research

Effect of bodyweight on VerifyNow Aspirin platelet function test: a retrospective review
Conclusions Bodyweight did not influence the likelihood of obtaining a therapeutic VerifyNow Aspirin result. The clinical utility of obtaining VerifyNow Aspirin assays for this patient population is unknown.
Source: Journal of NeuroInterventional Surgery - August 13, 2021 Category: Neurosurgery Authors: Sandler, M., Hoang, C., Mak, H. Y., Levitt, M. R. Tags: Hemorrhagic stroke Source Type: research

LB-005 The INSIGHT registry: a multi-center, multi-omic stroke clot study, preliminary results
ConclusionThese preliminary results demonstrate the real-world applicability of the INSIGHT study to typical stroke thrombectomy population. Furthermore, the tissue processing protocols are providing high-quality RNA and protein for analysis, which is currently underway.DisclosuresJ. Fraser: 1; C; Penumbra, University of Kentucky. 2; C; Stream Biomedical, Medtronic. 4; C; Cerelux, Fawkes Biotechnology. J. Vicari: None. A. Nanda: None. E. Cheng-Ching: None. K. Woodward: None. B. Rapoport: None. C. Kellner: None.
Source: Journal of NeuroInterventional Surgery - July 29, 2021 Category: Neurosurgery Authors: Fraser, J., Vicari, J., Nanda, A., Cheng-Ching, E., Woodward, K., Rapoport, B., Kellner, C. Tags: Late-breaking oral abstracts Source Type: research

O-005 Comparison of on-label versus off-label treatment of intracranial aneurysms with the pipeline embolization devices
ConclusionIn real-world practice, off-label uses of PED can achieve similar safety and efficacy to on-label uses, though there may be a slightly higher rate of ischemic complications in off-label uses. Expert judgment is a useful supplement to official guidelines when assessing reasonable PED use beyond its approved indications.Disclosures S. Cler: None. D. Lauzier: None. A. Kansagra: 2; C; Penumbra, Microvention, iSchemaView.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Cler, S., Lauzier, D., Kansagra, A. Tags: Oral abstracts Source Type: research

O-019 Increasing inner diameter leads to faster thrombectomy with aspiration in acute ischemic stroke
ConclusionThis multicenter, consecutive real-world experience demonstrates that M1 thrombectomy with a larger distal ID catheter is associated with faster time to recanalization and higher rate of TICI 2C or better recanalization on first pass, but also with a higher rate of hemorrhage on follow up imaging.Disclosures J. Vargas: 2; C; Cerenovus. 4; C; Truvic. S. Majidi: None. G. Cortez: None. A. Aghaebrahmin: None. E. Sauvageau: None. R. Hanel: 1; C; Microvention, Stryker. 2; C; Stryker, Medtronic, Cerenovus, Balt, Q’APel. 4; C; Rist. 6; C; MiVI. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: 2; C; Medtro...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Vargas, J., Majidi, S., Cortez, G., Aghaebrahmin, A., Sauvageau, E., Hanel, R., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Chen, C., Kellogg, R., Turk, A., Deleacy, R., Siddiqui, A., Oselkin, M., Marlin, E., TUrner, R., Chaudry, I., Milburn, J. Tags: Oral abstracts Source Type: research

P-005 Clot spatial heterogeneity rather than histologic composition is related to FPE rate
ConclusionSPI is a useful measure of clot structural heterogeneity and could provide more insights to improve the thrombectomy outcome compared to clot compositions.Disclosures Y. Liu: None. W. Brinjikji: None. M. Abbasi: None. D. Dai: None. J. Arturo Larco: None. D. Kallmes: None. L. Savastano: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Liu, Y., Brinjikji, W., Abbasi, M., Dai, D., Arturo Larco, J., Kallmes, D., Savastano, L. Tags: Oral poster abstracts Source Type: research

P-007 Safety and efficacy of endovascular thrombectomy for distal vessel occlusion (DLV): single center experience
ConclusionThis single center, consecutive real-world experience demonstrates that thrombectomy in DVO stroke patients is safe and leads to high rate of successful recanalization. Further studies are warranted to evaluate the efficacy of thrombectomy in DVO in comparison to best medical management.Disclosures S. Majidi: None. S. Matsoukas: None. R. De Leacy: None. T. Oxley: None. H. Shoirah: None. T. Shigematsu: None. C. Kellner: None. J. Fifi: None. J. Mocco: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Matsoukas, S., De Leacy, R., Oxley, T., Shoirah, H., Shigematsu, T., Kellner, C., Fifi, J., Mocco, J. Tags: Oral poster abstracts Source Type: research

P-009 An angled tip is associated with improved technical outcomes when using 0.064-0.074 aspiration catheters: analysis from a multicenter retrospective cohort
ConclusionThis multicenter, consecutive real-world experience demonstrates that M1 thrombectomy with an angled tip aspiration catheter is associated with higher rates of TICI 2C or better reperfusion, equal rates of TICI 2B or better reperfusion, and faster time to successful reperfusion.Disclosures J. Vargas: None. S. Majidi: None. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: None. R. Kellogg: None. G. Cortez: None. A. Aghaebrahim: None. E. Sauvageau: None. R. Hanel: None. R. De Leacy: None. A. Siddiqui: None. A. Turk: None. M. Oselkin: None. E. Marlin: None. R. Turner: None. I. Chaudry: None. J. Milburn: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Vargas, J., Majidi, S., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Kellogg, R., Cortez, G., Aghaebrahim, A., Sauvageau, E., Hanel, R., De Leacy, R., Siddiqui, A., Turk, A., Oselkin, M., Marlin, E., Turner, R., Chaudry, I., Milburn, J. Tags: Oral poster abstracts Source Type: research

P-012 Thrombectomy aspiration post-market study in acute stroke: the TAPAS study
ConclusionThe Q Aspiration Catheter is a novel technology that showed comparable deliverability and revascularization rates as other commercially available catheters with no safety concerns. More prospective clinical data is needed to fully assess the Q Aspiration Catheter.AbbreviationsAIS (acute ischemic stroke), MT (mechanical thrombectomy), ASPECTs (Alberta Stroke Program Early CT Score), mTICI (modified TICI score), NIHSS (National Institute of Health Stroke Scale), mRS (modified Rankin Scale), ENT (embolization to a new territory), sICH (symptomatic intracranial hemorrhage)Disclosures F. Ballenilla: 2; C; MIVI Neurosc...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ballenilla, F., Espinosa, M., Zamarro, J., Masso, J., Garmendia, E., Pumar, J., Larrea, J., Mosqueira, A. Tags: Oral poster abstracts Source Type: research

P-014 Reperfusion catheter malfunction during stroke intervention: an analytical review of the FDAs maude database
ConclusionReperfusion catheter failures resulting in injury or death are rare. These findings suggest that current methods of FDA surveillance have effectively identified outliers.Disclosures D. Bageac: None. B. Gershon: None. R. De Leacy: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Bageac, D., Gershon, B., De Leacy, R. Tags: Oral poster abstracts Source Type: research

P-015 The zoom system demonstrates higher first pass effect and faster reperfusion as compared to a consecutive contemporaneous series of aspiration catheters: analysis from a multicenter retrospective cohort
ConclusionThis retrospective, multicenter, consecutive real-world experience suggests that using Zoom 088 or 071 as primary aspiration catheter may demonstrate superior technical outcomes for M1 thrombectomy.Disclosures S. Majidi: None. J. Vargas: 2; C; Cerenovus, Medtronic. 4; C; Truvic. H. Hawk: None. S. Nimjee: None. A. Zakeri: None. M. Mokin: 2; C; Medtronic, Cerenovus. R. Kellogg: None. R. DeLeacy: None. G. Cortez: None. A. Aghaebrahmin: None. E. Sauvageau: None. R. Hanel: 1; C; Microvention, Stryker. 2; C; Medtronic, Microvention, Stryker, Balt, Cerenovus, Q’Apel. A. Siddiqui: 2; C; Imperitive Care, Medtronic, ...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Majidi, S., Vargas, J., Hawk, H., Nimjee, S., Zakeri, A., Mokin, M., Kellogg, R., DeLeacy, R., Cortez, G., Aghaebrahmin, A., Sauvageau, E., Hanel, R., Siddiqui, A., Oselkin, M., Marlin, E., Turk, A., Turner, R., Chaudry, I., Milburn, J. Tags: Oral poster abstracts Source Type: research

P-042 Initial experience with tenecteplase as the intravenous thrombolytic of choice before mechanical thrombectomy for large vessel occlusion acute ischemic stroke
ConclusionIntravenous TNK in patients with LVOAIS is feasible, safe and effective. In our cohort from ‘real world’ patients, TNK was associated with lower need for MT, high recanalization rates and shorter hospitalization.Disclosures U. Ugur: None. S. Platko: None. D. Peters: None. F. Bensabeur: None. J. Terry: None. B. Ludwig: None. E. Cheng-Ching: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ugur, U., Platko, S., Peters, D., Bensabeur, F., Terry, J., Ludwig, B., Cheng-Ching, E. Tags: Oral poster abstracts Source Type: research