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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

2-1-2 stroke microsurgical thrombectomy technique as a tertiary/salvage treatment option
CONCLUSIONS: 2-1-2 MST technique can be rapidly and efficaciously performed in a systemized manner offering a tertiary or salvage technique for acute stroke treatment. Specific microsurgical training is mandatory to accomplish this treatment and larger studies are necessary to confirm our hypothesis.PMID:35147401 | DOI:10.23736/S0390-5616.21.05480-1
Source: Journal of Neurosurgical Sciences - February 11, 2022 Category: Neurosurgery Authors: Marcelo M Oliveira Leonardo Avellar Jose A Malheiros Carlos E Ferrarez Geraldo M Lima Pollyana H Costa Source Type: research

Intra-arterial injection of mesenchymal stem cells to accelerate neointima formation after endovascular stenting in a rabbit model
CONCLUSIONS: The intra-arterial injection of MSCs after endovascular stenting accelerated early neointima formation but had no effect on thrombus formation in this study. Larger studies are required to verify these findings and determine the durability and mechanism of this effect.PMID:35090127 | DOI:10.3171/2021.11.JNS212372
Source: Journal of Neurosurgery - January 28, 2022 Category: Neurosurgery Authors: Kapilan Panchendrabose Sandeep Muram Brooke L Belanger Muneer Eesa Mohammed A Almekhlafi Mayank Goyal John H Wong Arindom Sen Bijoy K Menon Bryan Har Alim P Mitha Source Type: research

Bailout stentectomy of 47 self-expandable intracranial stents
Conclusion While various single devices can be used to safely retrieve dysfunctional intracranial self-expandable stents, dual-device techniques are more than twice as effective, according to our experience.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Chapot, R., Stracke, C. P., Wallocha, M., Rikhtegar, R., Yamac, E., Mosimann, P. J. Tags: Open access, New devices New devices and techniques Source Type: research

Per-pass analysis of acute ischemic stroke clots: impact of stroke etiology on extracted clot area and histological composition
Conclusion LAA clots are larger and associated with a large red blood cell-rich extracted clot area, suggesting soft thrombus material. Cardioembolic clots are smaller in the extracted clot area, consistent in composition and area across passes, and have higher fibrin and platelets/other content than LAA clots, making them stiffer clots. The per-pass histological composition and extracted clot area of cryptogenic clots are similar to those of cardioembolic clots, suggesting similar formation mechanisms.
Source: Journal of NeuroInterventional Surgery - November 18, 2021 Category: Neurosurgery Authors: Fitzgerald, S., Rossi, R., Mereuta, O. M., Jabrah, D., Okolo, A., Douglas, A., Molina Gil, S., Pandit, A., McCarthy, R., Gilvarry, M., Dunker, D., Nordanstig, A., Ceder, E., Redfors, P., Jood, K., Dehlfors, N., Magoufis, G., Tsivgoulis, G., Brinjikji, W., Tags: Open access, Ischemic stroke Source Type: research

Long-term Follow-up Results after Flow Diverter Therapy Using the Pipeline Embolization Device for Large or Giant Unruptured Internal Carotid Artery Aneurysms: Single-center Retrospective Analysis in the Japanese Population
Neurol Med Chir (Tokyo). 2021 Oct 27. doi: 10.2176/nmc.oa.2021-0203. Online ahead of print.ABSTRACTFlow diverter (FD) therapy using Pipeline embolization device (PED) has become an important alternative to treat internal carotid artery (ICA) aneurysms. Herein, we report the long-term outcome for 3 years after FD therapy using PED for ICA aneurysms in Japan. The patients who underwent angiographical and/or clinical follow-up for 3 years after the FD therapy using PED of large or giant unruptured ICA aneurysms from December 2012 at our university hospital are the subjects of this study. We retrospectively reviewed the in- an...
Source: Neurologia Medico-Chirurgica - October 28, 2021 Category: Neurosurgery Authors: Takashi Fujii Kohsuke Teranishi Kenji Yatomi Kazumoto Suzuki Yumiko Mitome-Mishima Akihide Kondo Hidenori Oishi Source Type: research

Dual-roadmap guidance for endovascular recanalization of medically refractory non-acute intracranial arterial occlusions: consecutive multicenter series and technical review
Conclusions Endovascular recanalization of non-acute intracranial occlusions can be performed with a high rate of technical success and few complications with assistance of the dual-roadmap technique for navigation. Four types of dual-roadmap schemes provide technical references.
Source: Journal of NeuroInterventional Surgery - September 15, 2021 Category: Neurosurgery Authors: Gao, F., Guo, X., Sun, X., Liu, Y., Wu, Y., Miao, Z. Tags: Ischemic stroke Source Type: research

High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke
Conclusions 3D-SEM provides novel and potentially clinically relevant information on clot components and ultrastructure which may help to inform thrombolytic treatment and medical device design.
Source: Journal of NeuroInterventional Surgery - September 15, 2021 Category: Neurosurgery Authors: Mereuta, O. M., Fitzgerald, S., Christensen, T. A., Jaspersen, A. L., Dai, D., Abbasi, M., Puttappa, T., Kadirvel, R., Kallmes, D. F., Doyle, K. M., Brinjikji, W. Tags: Ischemic stroke Source Type: research

EP46* First pass effect and associated clot characteristics in the EXCELLENT registry - Interim analysis
ConclusionsThe high rate of ‘real-world’ FPE observed in EXCELLENT was associated with improved clinical outcomes. Clots retrieved with FPE had higher RBC and lower fibrin content compared to non FPE and to first pass mTICI <2c/3 e. These preliminary findings await confirmation from analysis of the full dataset.DisclosureEXCELLENT is sponsored by Cerenovus. Dr. Jovin is a consultant for Neuravi, Codman Neurovascular, Stryker (PI DAWN; unpaid), Fundacio Ictus (PI REVASCAT; unpaid), and holds stock in Anaconda, Silk Road, and Blockade Medical.
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Jovin, T., Nogueira, R., Siddiqui, A., Yoo, A., Hanel, R., Zaidat, O., Hacke, W., Fiehler, J., De Meyer, S., Brinjikji, W., Doyle, K., Liebeskind, D., Haussen, D., Inoa, V., Humphries, W., Woodward, K., Jabbour, P., Francois, O., Levy, E., Bozorgchami, H. Tags: Treatment Source Type: research

EP50* Catheter tip distensibility substantially influences the aspiration force of thrombectomy devices
ConclusionsCatheter tip distensibility can induce a significant impact on ADAPT performance when retrieving a stiff clot larger than the device ID. Our findings might contribute to optimizing thrombectomy strategies.ReferencesSpiotta AM, Fargen KM, Chaudry MI, Turner R, Turk AS. ADAPT: a direct aspiration first pass technique. Stroke 2016;15(2):68–70.Froehler MT. Comparison of vacuum pressures and forces generated by different catheters and pumps for aspiration thrombectomy in acute ischemic stroke. Interv Neurol 2017;6(3–4):199–206. doi: 10.1159/000475478Yaeger K, et al. A technical comparison of thrombe...
Source: Journal of NeuroInterventional Surgery - August 24, 2021 Category: Neurosurgery Authors: Li, J., Castano, O., Tomasello, A., De Dios, M., Canals, P., Engel, E., Ribo, M. Tags: Treatment Source Type: research