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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

E-166 The effect of covid-19 on treatment and outcomes following ischemic stroke: a national assessment
ConclusionThis study identified a relationship between COVID-19 diagnosis and worse outcomes for each metric assessed. Most notably, even when controlling for disease-related factors, patients with COVID-19 were significantly less likely to undergo mechanical thrombectomy. Further, COVID-19 was associated with increased in-hospital mortality and worsened discharge disposition, although the exact causal relationship of this is unclear. Several factors might underly this, ranging from systemic/multisystem inflammation and worsened disease severity to logistical barriers to treatment caused by COVID-19. Further research is ne...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Dallas, J., Liu, K., Wenger, T., Lin, M., Ding, L., Attenello, F., Mack, W. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-189 Outcomes of tenecteplase versus alteplase after mechanical thrombectomy in a multiethnic stroke consortium registry
ConclusionIn this prospective, multi-center stroke consortium study, IV TNK in comparison to tPA prior to MT for ischemic stroke resulted in non-inferior outcomes related to angiographic reperfusion and functional status at discharge. These findings compliment the current literature and include a large Hispanic US cohort. Further analysis will include expansion of contributing centers and use of propensity scoring.Abstract E-189 Table 1 and 2Disclosures M. Gaub: None. D. Ramaswamy: None. A. Cardentey: None. S. Bandela: None. G. Gealogo: None. J. Mascitelli: None. F. Al Saiegh: None. L. Birnbaum: 2; C; Rapid AI, Imperative Care.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Gaub, M., Ramaswamy, D., Cardentey, A., Bandela, S., Gealogo, G., Mascitelli, J., Al Saiegh, F., Birnbaum, L. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-194 One road to two places: a unique case report of bilateral thalamic infarctions with neuroanatomical anomaly
ConclusionThe scientific relevance of the present case is to address various etiologies of bilateral thalamic stroke with special attention to single artery causes of bilateral strokes versus other causes of bilateral thalamic strokes. It is important to consider bilateral ischemic pathology, even as might arise from a single artery, as a differential in cases of acute encephalopathy. Reviewing the various etiologies of cerebral infarction can improve patient outcomes and provide a comprehensive understanding of the patients’ presenting symptomatology.A practice gap exists in the identification and treatment of bilat...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Nittala, S., Mercho, P., Hussaini, S., Youssef, P., Oliu, C. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-203 Dynamic extrinsic compression of extracranial cerebral arteries causing recurrent strokes
ConclusionThese cases illustrate an uncommon stroke etiology from dynamic extrinsic compression of extracranial cerebral arteries. Considering such a cause should be taken into account in patients presenting with recurrent, cryptogenic strokes.Abstract E-203 Figure 1Disclosures J. Choi: None. R. Zhang: None. S. Tsappidi: None. Y. Zhang: None. F. Hui: None. S. Brown: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Choi, J., Zhang, R., Tsappidi, S., Zhang, Y., Hui, F., Brown, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-225 Incidence of plaque protrusion during and after carotid artery stenting using micromesh stent
ConclusionMicromesh stent seemed to reduce ischemic complication by preventing PP during CAS. In addition, delayed PP also should be carefully followed-up.Disclosures K. Takayama: None. K. Myouchin: None. T. Wada: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Takayama, K., Myouchin, K., Wada, T. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-226 Endovascular treatment of pediatric arteriovenous shunts
ConclusionEndovascular treatment of pediatric arteriovenous shunts is extremely difficult and associated with high risks of complications. However, excellent clinical results can be achieved in specialized clinics. The choice of embolic agent should depend on the hemodynamic load of the pathological blood flow.Disclosures V. Berestov: None. K. Orlov: None. N. Strelnikov: None. A. Brusyanskaya: None. A. Somova: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Berestov, V., Orlov, K., Strelnikov, N., Brusyanskaya, A., Somova, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-241 Clinicopathologic analysis of COVID-19 associated thrombi in the setting of large vessel occlusion: a prospective case control study
ConclusionThrombi retrieved from COVID-19 positive stroke patients demonstrated RBC predominance. This finding requires further investigation using appropriate immunohistochemical techniques in a larger cohort of patients.Abstract E-241 Figure 1Abstract E-241 Figure 2COVID-19 positive patient thrombus; stained with H&E demonstrating predominantly RBCs (solid yellow arrow) with interspersed fibrin (solid black arrow) and platelets. Original magnification X100Disclosures R. Floresca: None. F. Sheriff: None. J. Lavezo: None. M. Chaudhury: None. G. Colina: None. R. Regenhardt: None. V. Gupta: None. G. Rodriguez: None. A. Maud: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Floresca, R., Sheriff, F., Lavezo, J., Chaudhury, M., Colina, G., Regenhardt, R., Gupta, V., Rodriguez, G., Maud, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-257 Flow diversion of the ophthalmic aneurysms, outcomes in relation to the ophthalmic artery origin
ConclusionFlow diversion is safe and effective for carotid ophthalmic aneurysms treatment. Adjunct coil embolization and ophthalmic artery origin in relation to the aneurysm sac are independent factors that can influence treatment result, and should be considered when planning treatment.Disclosures M. Abdulrazzak: None. A. Alrohimi: None. A. Pandhi: None. T. Patterson: None. N. Moore: None. J. Tsai: None. M. Bain: None. M. Hussain: None. T. Masaryk: None. P. Rassmusen: None. G. Toth: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Abdulrazzak, M., Alrohimi, A., Pandhi, A., Patterson, T., Moore, N., Tsai, J., Bain, M., Hussain, M., Masaryk, T., Rassmusen, P., Toth, G. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-260 Bilateral cerebral arteriovenous shunting through pial and perforating vessels with multiple strokes and intraparenchymal hemorrhages in a patient with hepatopulmonary syndrome
This study presents a unique case of a 54-year-old male patient with a history of stroke, liver cirrhosis, portal vein thrombosis, hypertension, diabetes, and bladder cancer, who experienced multiple episodes of intracranial hemorrhages, stroke and worsening confusion over the past five years. The patient‘s clinical presentation raised suspicion for an underlying occult vasculopathy. Digital subtraction angiography (DSA) revealed multiple curvilinear, irregular, bilateral pial vessels with early high-flow arteriovenous shunting, consistent with vascular shunting that is associated with liver cirrhosis. The patient&ls...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Aljeradat, B., Koneru, M., Oliveira, R., Shaikh, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Use of intravenous cangrelor in the treatment of ruptured and unruptured cerebral aneurysms: an updated single-center analysis and pooled analysis of current studies
Conclusions IV cangrelor during aneurysm embolization appears to be safe, with a symptomatic intracranial hemorrhage rate of 4% in ruptured cases and 2.6% in unruptured cases. More research is needed to determine the ideal dosing regimen.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Entezami, P., Dalfino, J. C., Boulos, A. S., Yamamoto, J., Holden, D. N., Field, N. C., Rock, A. K., Najera, E., Paul, A. R. Tags: New devices New devices and techniques Source Type: research

Thrombosis origin identification of cardioembolism and large artery atherosclerosis by distinct metabolites
Conclusions Six metabolites as potential predictors for distinguishing between cerebral thrombi of CE and LAA origin were identified. The results are useful for understanding the pathogenesis and for secondary stroke prevention.
Source: Journal of NeuroInterventional Surgery - June 16, 2023 Category: Neurosurgery Authors: Li, W., Bai, X., Hao, J., Xu, X., Lin, F., Jiang, Q., Ding, C., Dai, G., Peng, F., Zhang, M., Feng, Y., Wang, J., Chen, X., Xue, T., Guo, X., Fu, Z., Chen, W.-h., Zhang, L., Wang, C., Jiao, L. Tags: Basic science Source Type: research

Impedance-based sensors discriminate among different types of blood thrombi with very high specificity and sensitivity
Conclusions Combining EIS measurements with machine learning provides a highly effective approach for discriminating among different thrombus types and liquid blood. These findings raise the possibility of developing a probe-like device (eg, a neurovascular guidewire) integrating an impedance-based sensor. This sensor, placed in the distal part of the smart device, would allow the characterization of the probed thrombus on contact. The information could help physicians identify optimal thrombectomy strategies to improve outcomes for stroke patients.
Source: Journal of NeuroInterventional Surgery - May 16, 2023 Category: Neurosurgery Authors: Messina, P., Garcia, C., Rambeau, J., Darcourt, J., Balland, R., Carreel, B., Cottance, M., Gusarova, E., Lafaurie-Janvore, J., Lebedev, G., Bozsak, F., Barakat, A. I., Payrastre, B., Cognard, C. Tags: Open access, Ischemic stroke Source Type: research

Early recanalization with intravenous thrombolysis before mechanical thrombectomy: considerations to explore with tenecteplase
Time is brain. Hence, timely reperfusion in emergent large vessel occlusion (LVO) stroke is critical for favorable outcomes. Intravenous thrombolysis with alteplase (TPA) before mechanical thrombectomy (MT) for emergent LVO stroke is associated with significantly higher rates of preinterventional reperfusion than MT alone. Recent post hoc analyses of SWIFT-DIRECT and DIRECT-MT have shown that times longer than 30 min since TPA administration are associated with increased reperfusion rates.1 2 The incremental increase of reperfusion rates with longer times since TPA administration underpins TPA’s time dependence to ex...
Source: Journal of NeuroInterventional Surgery - April 13, 2023 Category: Neurosurgery Authors: Hendrix, P., Schirmer, C. M. Tags: Letter Source Type: research

Bifurcation occlusions and endovascular treatment outcome in acute ischemic stroke
Conclusions In our population, EVT procedural and long-term clinical outcomes were similar for MCA bifurcation occlusions and MCA main stem occlusions.
Source: Journal of NeuroInterventional Surgery - March 14, 2023 Category: Neurosurgery Authors: Arrarte Terreros, N., Bruggeman, A. A. E., van Voorst, H., Konduri, P. R., Jansen, I. G. H., Kappelhof, M., Tolhuisen, M. L., Boodt, N., Dippel, D. W. J., van der Lugt, A., van Zwam, W. H., van Oostenbrugge, R. J., van der Worp, H. B., Emmer, B. J., Meije Tags: Open access, Ischemic stroke Source Type: research

Mechanical thrombectomy for acute paradoxical cerebral embolism due to pulmonary arteriovenous malformation: A case report and review of literature
CONCLUSION: Although rare, PAVM is a treatable cause of stroke in relatively young adults; thus, it is important to keep in mind the possibility of its presence.PMID:36751447 | PMC:PMC9899467 | DOI:10.25259/SNI_987_2022
Source: Surgical Neurology International - February 8, 2023 Category: Neurosurgery Authors: Satoshi Inoue Atsushi Fujita Eiji Kurihara Takashi Sasayama Source Type: research