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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

Thrombus imaging characteristics within acute ischemic stroke: similarities and interdependence
Conclusions Thrombus imaging characteristics are significantly intercorrelated – strong correlations should be considered in future predictive modeling studies. Clustering analysis showed there are no distinct thrombus archetypes – novel treatments should consider this thrombus variability.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: Arrarte Terreros, N., Bruggeman, A. A., Kappelhof, M., Tolhuisen, M. L., Brouwer, J., Hoving, J. W., Konduri, P. R., van Kranendonk, K. R., Dutra, B. G., Alves, H. C., Dippel, D. W., van Zwam, W. H., Beenen, L. F., Yo, L. S., van Bavel, E., Majoie, C. B., Tags: Open access, Ischemic stroke Source Type: research

Thrombus radiomics in patients with anterior circulation acute ischemic stroke undergoing endovascular treatment
Conclusions TR describing thrombus volume and texture were associated with more attempts to successful reperfusion. Compared with models using CV and MTM, TR had no added value for predicting procedural and functional outcome.
Source: Journal of NeuroInterventional Surgery - August 29, 2023 Category: Neurosurgery Authors: van Voorst, H., Bruggeman, A. A. E., Yang, W., Andriessen, J., Welberg, E., Dutra, B. G., Konduri, P. R., Arrarte Terreros, N., Hoving, J. W., Tolhuisen, M. L., Kappelhof, M., Brouwer, J., Boodt, N., van Kranendonk, K. R., Koopman, M. S., Hund, H. M., Kri Tags: Ischemic stroke Source Type: research

P135/313 Predictive value of CT head and CT angiogram in identifying ICAD associated large vessel occlusion
ConclusionOur findings suggest a significant association between the absence of the hyperdense artery sign and the presence of tapering at the occlusion site with ICAD in patients with LVO. Incorporating these signs in pre-thrombectomy evaluation has the potential to improve stroke care.Disclosure of InterestDr. Joe Leyon has/had consultancy agreements with Microvention Terumo, Medtronic, and Stryker Neurovascular.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Hassan, A., Leyon, J., Kaya, A. Tags: 2.1 ISCHEMIC - Logistics Source Type: research

P151/175 Direct aspiration with EMBOVAC - first clinical experience and clot composition (results the "PERFECT study)
ConclusionThis is the first clinical evaluation of EMBOVAC. Direct aspiration with EMBOVAC as first line therapy resulted in high rates of reperfusion and favorable clinical outcomes. Clot composition analysis can aid in better understanding of the stroke etiology and means for effective clot removal.Disclosure of InterestAcandis (OJ, CL, JF); Microvention (GM, CC, JF); Stryker (GM, CC, JF); Medtronic (GM, CC, JF); Surge2surgery (BG); MIVI (CC); Phenox (CL, JF); Penumbra (CL, JF); GSK (AS); German Ministry of Science & Education and Economy & Innovation, EU, Hamburgische Investitions-/Förderbank, Philips, B...
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Lobotesis, K., Jansen, O., Marnat, G., Gory, B., Nordmeyer, H., Eckert, B., Alessandro, P., Cognard, C., Loehr, C., Bracco, S., Schaefer, A., Macera, A., Fiehler, J., Doyle, K., Piano, M. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

P164/236 Antithrombotic regimen in emergent carotid stenting for acute ischemic stroke due to tandem lesion: a meta-analysis of aggregate data
ConclusionsIn AIS due to tandem occlusion, the periprocedural antithrombotic regimen of eCAS seems to have a marginal effect on good functional outcome. Overall, high intensity antithrombotic therapy may provide a marginal benefit on good functional outcome and carotid stent patency without a significant increase in risk of sICH.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Diana, F., Abdalkader, M., Behme, D., Li, W., Maurer, C. J., Pop, R., Hwang, Y.-H., Bartolini, B., Ros, V. D., Bracco, S., Cirillo, L., Marnat, G., Katsanos, A., Kaesmacher, J., Fischer, U., Sousa, D. A. d., Peschillo, S., Zini, A., Tomasello, A., Ribo, M Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O21/183 Stenting of intracranial stenosis with the fibrin-heparin coated Credo heal stent -multicenter experience
ConclusionThe Credo heal stent offers a treatment option for patients with sICAD or with persistent occlusion. The rate of restenosis is low compared to previous trials. Its effectiveness with regard to long-term ischemic complications will be evaluated in the prospective ReCHRUT trial.Disclosure of InterestHannes Nordmeyer and Franziska Dorn received speaker honoraria from Acandis. All other author have nothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nordmeyer, H., Dorn, F., Leo, V., Mousa, Z. Tags: 2.3 ISCHEMIC - Treatment Source Type: research

O37/346 Endovascular treatment of cerebral venous thrombosis: a single center experience
ConclusionSince the advent of EVT for the AIS, the improvement of the devices and the endovascular techniques have increased, opening a new scenario for the treatment of the CVT in terms of efficacy and safety.Our study add evidence on the safety and efficacy of the endovascular techniques in the treatment of CVT.Disclosure of Interestnothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Piano, M., Macera, A., Cervo, A., Vitiello, A., Lozupone, E., Pero, G. Tags: 3.3 OTHER - Miscellaneous Source Type: research

P012/110 Flow diversion in a giant fusiform M2 aneurysm: very delayed parent vessel occlusion and post-thrombectomy re-in-stent thrombosis
ConclusionVery delayed in-stent thrombosis and subsequent parent vessel occlusion can occur after flow diversion procedures.Disclosure of InterestAK: Nothing to discloseMB: Consultant for Microvention, Cerenovus, Acandis, and RapidJF: The Co-author reports personal fees from Consultant for Acandis, Cerenovus, Medtronic, Microvention, Phenox, Penumbra, Roche, Tonbridge outside of the submitted work. He is a member of the Executive Board of the scientific societies DGNR and the President of ESMINT and holds Stock in Vastrax LLC and Tegus.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Kyselyova, A. A., Fiehler, J., Bester, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

P014/130 Treatment of recurrent intracranial atherosclerotic disease-related stroke due to in-stent thrombosis with the CREDO(R) heal stent: A case report
ConclusionThis case highlights that re-stenting a recurrent ICAD-related stroke using the CREDO® heal stent is technically feasible, safe, and may improve clinical outcomes.Disclosure of InterestNothing to disclose.
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Nguyen, A., Schulze-Zachau, V., Psychogios, M. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

Introduction
Dear SNIS 20th Annual Meeting Attendee,The editorial board of the Journal of NeuroInterventional Surgery (JNIS) is pleased to provide this supplement containing abstracts of the state-of-the-art neurointerventional research that will be presented at this year’s annual meeting.The abstracts in this supplement represent the best scientific work in the neurointerventional field. The JNIS editorial board hopes that these abstracts serve as a catalyst for further endovascular research and improvements in patient care. This year’s supplement features a variety of abstracts pertaining to contemporary issues. These inc...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Tags: Introduction Source Type: research

O-010 Tigertriever in the treatment of acute ischemic stroke in patients with underlying intracranial atherosclerotic disease
ConclusionTigertriever exerts a higher radial force that can be manually tailored to achieve better recanalization in patients with LVO due to ICAD.ReferenceGupta R, Saver JL, Levy E, et al. New class of radially adjustable stentrievers for acute ischemic stroke: primary results of the multicenter TIGER trial. Stroke. May 2021;52(5):1534-1544. doi:10.1161/strokeaha.121.034436Abstract O-010 Figure 1(A) A right Ml occlusion due to underlying ICAD (arrowhead). (B) The Tigertriever is deployed across the stenosis. The device ‘massages’ the thrombus and exerts an increased radial force in stenotic lesions due to ICA...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ojeda, D., Sanchez, S., Miller, J., Almajali, M., Koul, P., Noboa, L., Ghannam, M., Samaniego, E. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-012 Relationship between clot composition and procedural results for ischemic stroke aspiration thrombectomy: subset analysis from the INSIGHT registry
ConclusionsClot removed during neuroendovascular procedures can differ in consistency and removability, leading to an increased focus on thrombus composition as a crucial variable for improving outcomes of ischemic stroke. In this study, good final revascularization (mTICI 2b-3 at the final angiogram) occurred after aspiration thrombectomy regardless of clot composition. Ongoing analysis of collected specimens is expected to provide valuable information regarding thrombus biology and etiology and to aid in diagnosis, prognosis, and drug development.Abstract O-012 Table 1Clot composition vs procedural results for ischemic s...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Kellner, C., Dabney, A., Baltan, S., Sohrabji, F., Pennypacker, K., Nanda, A., Woodward, K., Rivet, D., Fraser, J. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-016 Thrombus permeability is associated with distinct proteomic features and differential susceptibility to adamts13 thrombolysis
ConclusionThrombus permeability is associated with distinguishable proteomics features, including greater abundance of platelet-related proteins in highly permeable clots and monocyte/macrophages in less permeable clots. These findings also suggest that highly pervious thrombi may be differentially susceptible to ADAMTS13 augmented thrombolysis.Disclosures D. Schartz: None. S. Akkipeddi: None. N. Ellens: None. R. Rahmani: None. G. Kohli: None. R. Ismail: None. S. Chittaranjan: None. K. Welle: None. T. Bhalla: None. T. Mattingly: None. C. Morrell: None. M. Bender: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Schartz, D., Akkipeddi, S., Ellens, N., Rahmani, R., Kohli, G., Ismail, R., Chittaranjan, S., Welle, K., Bhalla, T., Mattingly, T., Morrell, C., Bender, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

O-035 Endovascular treatment of cerebral venous thrombosis involving the deep venous system
ConclusionsAlthough deep venous involvement of CVT is uncommon, these patients are at risk of quickly becoming critically ill with an elevated rate of death or dependency. Although these patients may develop stroke, hemorrhage, or neurologic decline prompting consideration of endovascular therapy, the deep cerebral venous system is not easily accessible with catheters due to small lumens and risk of perforation. It has been proposed that deep cerebral veins may have a higher chance of recanalization if venous thrombus burden is reduced in other parts of the dural venous sinuses. Current literature has not fully explored th...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Morel, B., Hoffman, J., Folzenlogen, Z., Roark, C., Seinfeld, J., Case, D. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

P-003 The zoomTMRDL radial access system for neurointervention: an early single-center experience
ConclusionsThe use of Zoom RDLTM Radial Access System is technically feasible and effective for complex neurointerventional procedures with low complication rates.Disclosures R. Morsi: None. S. Kothari: None. S. Thind: None. H. Desai: None. S. Polster: None. F. Goldenberg: None. E. Coleman: None. J. Brorson: None. S. Mendelson: None. A. Mansour: None. S. Prabhakaran: None. T. Kass-Hout: 2; C; Brainomix: Consultant, Cerenovus: Consultant, Imperative Care: Consultant, Medtronic Inc.: Consultant, Microvention: Consultant, Stryker Neurovascular: Consultant.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Morsi, R., Kothari, S., Thind, S., Desai, H., Polster, S., Goldenberg, F., Coleman, E., Brorson, J., Mendelson, S., Mansour, A., Prabhakaran, S., Kass-Hout, T. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research