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Specialty: Neurosurgery
Condition: Thrombosis

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Total 559 results found since Jan 2013.

Acute ischemic stroke in a child due to basilar artery occlusion treated successfully with a stent retriever
We present the case of a 22-month-old child with acute ischemic stroke due to basilar artery occlusion that was successfully treated with a stent retriever.
Source: Journal of NeuroInterventional Surgery - July 13, 2016 Category: Neurosurgery Authors: Savastano, L., Gemmete, J. J., Pandey, A. S., Roark, C., Chaudhary, N. Tags: Electronic pages Source Type: research

Endovascular stroke therapy with the Aperio thrombectomy device
Conclusions The Aperio thrombectomy device seems to be an effective and adequately safe tool for reopening occluded cerebral arteries in the setting of acute stroke.
Source: Journal of NeuroInterventional Surgery - July 13, 2016 Category: Neurosurgery Authors: Kallenberg, K., Solymosi, L., Taschner, C. A., Berkefeld, J., Schlamann, M., Jansen, O., Arnold, S., Tomandl, B., Knauth, M., Turowski, B. Tags: New devices Source Type: research

Thrombolytic Treatment to Stroke Mimic Patients via Telestroke
The safety of intravenous thrombolysis (IVT) use among patients presenting with conditions mimicking acute ischemic stroke (AIS) is well established [1]. Rates of patients with stroke mimics (SM) treated with IVT at community hospitals who follow a “drip-and-ship” paradigm is higher than rates found for those presenting to stroke centers [2]. The implementation of telestroke (TS) where neurologists are connected to hospitals in areas without on-site neurological expertise has been proven to be effective in the safe implementation of IVT [3 ].
Source: Clinical Neurology and Neurosurgery - December 13, 2016 Category: Neurosurgery Authors: Ganesh Asaithambi, Amy L. Castle, Michael A. Sperl, Jayashree Ravichandran, Aditi Gupta, Bridget M. Ho, Sandra K. Hanson Source Type: research

Posterior circulation cerebrovascular syndromes: diagnosis and management
One in five strokes affects the posterior circulation. Diagnosing posterior circulation stroke can be challenging, as the vascular anatomy can be variable, and because presenting symptoms are often non-specific and fluctuating. Nevertheless, making the correct diagnosis is important, as these strokes have a high chance of recurrence, can be life threatening, and can lead to equally life-threatening complications. Investigation and management largely follow those for stroke in general, although some specific differences exist. These include the preferred use of MRI for diagnosing posterior fossa lesions, the management of b...
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 14, 2016 Category: Neurosurgery Authors: Schulz, U. G., Fischer, U. Tags: Stroke Cerebrovascular disease Source Type: research

'Last known well alone should not determine triage for patients with stroke and symptoms of large vessel occlusion
The term ‘last known well’ (LKW) is ingrained in the culture of stroke treatment. There are good reasons for this. Successful acute thrombolytic trials used LKW as an entry criterion to prove the efficacy of IV thrombolysis.1 2 Based on the results of those trials, treatment of acute stroke with IV thrombolysis is a class 1 recommendation for patients presenting with acute stroke symptoms within 3–4.5 h of LKW.3 Few vascular neurologists will recommend IV thrombolysis for patients outside the time window established by LKW, and hence this term represents a crucial time metric for thrombolytic therapy...
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Heck, D. V., Grotta, J. C. Tags: Editorials Source Type: research

Combined proximal balloon occlusion and distal aspiration: a new approach to prevent distal embolization during neurothrombectomy
Conclusions A combination of proximal internal carotid artery occlusion using a balloon catheter and distal aspiration through an intermediate catheter represents a safe and efficient adjunct to mechanical thrombectomy with stent retrievers. In our patient cohort, no new thrombembolic complications were detected.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Stampfl, S., Pfaff, J., Herweh, C., Pham, M., Schieber, S., Ringleb, P. A., Bendszus, M., Möhlenbruch, M. A. Tags: Ischemic stroke Source Type: research

Elevated Blood Urea Nitrogen/Creatinine Ratio Is Associated with Venous Thromboembolism in Patients with Acute Ischemic Stroke.
Conclusion: Dehydration on admission in cases of AIS might be a significant independent risk factor for VTE. PMID: 29142620 [PubMed]
Source: Journal of Korean Neurosurgical Society - November 18, 2017 Category: Neurosurgery Tags: J Korean Neurosurg Soc Source Type: research

Risk factors for decompressive craniectomy after endovascular treatment in acute ischemic stroke
This study aimed to evaluate the risk factors for subsequent DC after EVT. This retrospective cohort study comprised 138 patients who received EVT between April 2015 and June 2019 at our center. The need for subsequent DC was defined as cerebral edema or/and hemorrhagic transformation caused by large ischemic infarction, with a ≥ 5-mm midline shift and clinical deterioration after EVT. The relationship between risk factors and DC after EVT was assessed via univariate and multivariable logistic regression. Thirty (21.7%) patients required DC. These patients tended to have atrial fibrillation (P = 0.037), sedation (P...
Source: Neurosurgical Review - September 3, 2019 Category: Neurosurgery Source Type: research

Analysis of human emboli and thrombectomy forces in large-vessel occlusion stroke.
CONCLUSIONS: Current thrombectomy devices remove emboli mostly by applying linear tensile forces, under which emboli elongate until dissociation. Embolus resistance to dissociation is determined by embolus strength, which significantly correlates with composition and varies within and among patients and within the same thrombus. The dynamic intravascular weakening of emboli during removal may lead to iatrogenic embolization. PMID: 32109875 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 27, 2020 Category: Neurosurgery Authors: Liu Y, Zheng Y, Reddy AS, Gebrezgiabhier D, Davis E, Cockrum J, Gemmete JJ, Chaudhary N, Griauzde JM, Pandey AS, Shih AJ, Savastano LE Tags: J Neurosurg Source Type: research

A lower admission level of interleukin-6 is associated with first-pass effect in ischemic stroke patients
Conclusion A lower admission level of IL-6 is associated with FPE.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Mechtouff, L., Bochaton, T., Paccalet, A., Crola Da Silva, C., Buisson, M., Amaz, C., Derex, L., Ong, E., Berthezene, Y., Dufay, N., Ovize, M., Mewton, N., Cho, T.-H., Nighoghossian, N., Eker, O. F. Tags: Vascular neurology Source Type: research

Early recanalization in large-vessel occlusion stroke patients transferred for endovascular treatment
Conclusions Early recanalization is associated with clinical improvement between PSC and CSC admission, more distal occlusions and shorter thrombi at baseline imaging, and better functional outcome.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Arrarte Terreros, N., Bruggeman, A. A. E., Swijnenburg, I. S. J., van Meenen, L. C. C., Groot, A. E., Coutinho, J. M., Roos, Y. B. W. E. M., Emmer, B. J., Beenen, L. F. M., van Bavel, E., Marquering, H. A., Majoie, C. B. L. M. Tags: Open access Vascular neurology Source Type: research

O-020 The tigertriever 13 distals study: distal ischemic stroke treatment with adjustable low-profile stentriever
ConclusionThe TIGERTRIEVER 13 device with operator controllability and high fluoroscopy visibility and its small size can potentially provide a safe and effective clot removal in patients with distal vessels occlusion.Disclosures D. Fiorella: 1; C; Rapid Medical. R. Gupta: None. R. Chapot: None. J. Saver: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fiorella, D., Gupta, R., Chapot, R., Saver, J. Tags: SNIS 19th annual meeting oral abstracts Source Type: research

P-031 End artery location of thrombus predicts poor neurological outcome despite successful thrombectomy for anterior circulation stroke
ConclusionsDespite similar vascular territories, concurrent occlusion of the MCA and ACA segments results in worse clinical outcomes compared to more proximal ICA occlusion. The likely explanation for fast progression of infarct in the MCA+ACA group is the higher likelihood of end-artery involvement and lower contribution of collateral flow. Reperfusion of both territories; however, does add to the risk of symptomatic post-procedural hemorrhage.Disclosures S. Eshraghi: None. S. Saperian: None. A. Alawieh: None. B. Howard: None. J. Grossberg: None. F. Tong: None. P. Jabbour: None. I. Maier: None. S. Wolfe: None. A. Rai: Non...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Eshraghi, S., Saperian, S., Alawieh, A., Howard, B., Grossberg, J., Tong, F., Jabbour, P., Maier, I., Wolfe, S., Rai, A., Starke, R., Gory, B., Psychogios, M., Shaaban, A., Arthur, A., Kim, J., Yoshimura, S., Kan, P., DeLeacy, R., Fragata, I., Polifka, A. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research

O-010 Tigertriever in the treatment of acute ischemic stroke in patients with underlying intracranial atherosclerotic disease
ConclusionTigertriever exerts a higher radial force that can be manually tailored to achieve better recanalization in patients with LVO due to ICAD.ReferenceGupta R, Saver JL, Levy E, et al. New class of radially adjustable stentrievers for acute ischemic stroke: primary results of the multicenter TIGER trial. Stroke. May 2021;52(5):1534-1544. doi:10.1161/strokeaha.121.034436Abstract O-010 Figure 1(A) A right Ml occlusion due to underlying ICAD (arrowhead). (B) The Tigertriever is deployed across the stenosis. The device ‘massages’ the thrombus and exerts an increased radial force in stenotic lesions due to ICA...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ojeda, D., Sanchez, S., Miller, J., Almajali, M., Koul, P., Noboa, L., Ghannam, M., Samaniego, E. Tags: SNIS 20th annual meeting oral abstracts Source Type: research