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Cerebral Venous Sinus Thrombosis Incidence Is Higher Than Previously Thought: A Retrospective Population-Based Study Clinical Sciences
Conclusions— Cerebral venous sinus thrombosis in our study was more common than previously reported, perhaps because of more complete ascertainment. Future CVT incidence studies should include comprehensive capture and review of neuroimaging.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Devasagayam, S., Wyatt, B., Leyden, J., Kleinig, T. Tags: Epidemiology, Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Thrombosis Clinical Sciences Source Type: research

Identification of Reversible Disruption of the Human Blood-Brain Barrier Following Acute Ischemia Brief Reports
Conclusions— This study demonstrates that diffuse, mild BBB disruption in the acutely ischemic human brain is reversible with reperfusion. This study also confirms prior findings that focal severe BBB disruption confers an increased risk of hemorrhagic transformation in patients treated with intravenous tissue-type plasminogen activator.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Simpkins, A. N., Dias, C., Leigh, R., on behalf of the National Institutes of Health Natural History of Stroke Investigators, Benson, Hsia, Latour, Luby, Lynch, Merino, Nadareishvili, Warach Tags: Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Multiple Cerebral Infarctions in a Patient with Adenomyosis on Hormone Replacement Therapy: A Case Report
A 59-year-old woman was admitted to our hospital because of repeated episodes of bilateral hand weakness. She had a 10-year history of combined estrogen –progestin therapy for menopausal symptoms. Magnetic resonance imaging on admission showed multiple hyperintense lesions in bilateral cerebral and cerebellar cortices on diffusion-weighted imaging. Transesophageal echocardiography showed thrombus formation on the aortic valve and moderate aortic i nsufficiency. Laboratory test demonstrated elevated CA125 (334.8 U/mL) and D-dimer (7.0 µg/mL) levels.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2016 Category: Neurology Authors: Nanako Hijikata, Yuki Sakamoto, Chikako Nito, Noriko Matsumoto, Arata Abe, Akane Nogami, Takahiro Sato, Hiroyuki Hokama, Seiji Okubo, Kazumi Kimura Tags: Case Studies Source Type: research

Stroke: Highlights of Selected Articles Stroke: Highlights of Selected Articles
Source: Stroke - June 26, 2016 Category: Neurology Tags: Stem Cells, Magnetic Resonance Imaging (MRI), Quality and Outcomes, Ischemic Stroke, Thrombosis Stroke: Highlights of Selected Articles Source Type: research

The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis mimicking an acute stroke
ConclusionsThe decision to thrombolyse or perform an LP in HaNDL patients mimicking a stroke is difficult in the acute setting. Perfusion CT can provide misleading results and CTA may be useful in ruling out occlusion of a cerebral vessel.
Source: European Journal of Neurology - April 22, 2016 Category: Neurology Authors: M. Guillan, A. DeFelipe‐Mimbrera, A. Alonso‐Canovas, M. C. Matute, R. Vera, A. Cruz‐Culebras, N. Garcia‐Barragan, J. Masjuan Tags: Original Article Source Type: research

Plaque Inflammation in Recently Symptomatic Carotid Stenosis Predicts Recurrent Cerebral Ischemia (P1.233)
Conclusions: FDG-PET/CT and HR-MRI aid in the imaging of plaque inflammation and identification of patients with higher risk of subsequent cerebral ischemic events. This ongoing study intends to develop a robust prediction model for risk stratification based on luminal stenosis and plaque characteristics for better therapeutic decision-making.Disclosure: Dr. Woo has nothing to disclose. Dr. Bharatendu has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Paliwal has nothing to disclose. Dr. Kulkarni has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing t...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Woo, J. W., Bharatendu, C., Sinha, A., Ting, E., Paliwal, P., Kulkarni, A., Teoh, H. L., Chan, B., Hong, C., Heng, C. Y., Chen, J. T., Du, Z., Wong, L., Asp, S., Sharma, V. Tags: Carotid Disease Source Type: research

Aortic Sarcoma Mimicking a Thrombus Filling Vascular Lumen: A Rare Cause of Cerebral Infarction (P4.364)
Conclusion- Primary aortic sarcoma is an extremely rare cause of stroke. This sarcoma may be misinterpreted as a thrombus filling vascular lumen on CT angiography, but no elevation of D-dimer is incompatible with a large thrombus. The final diagnosis can be made by surgical biopsy.Disclosure: Dr. Kim has nothing to disclose. Dr. Jeon has nothing to disclose. Dr. Park has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Kwon has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kim, H., Jeon, S.-B., Park, K.-W., Kim, H., Kim, B. J., Kwon, S. Tags: Cerebrovascular Case Reports Source Type: research

Obesity, Oral Contraceptive Use, and Cerebral Venous Thrombosis
Cerebral venous thrombosis (CVT) is an uncommon cause of stroke that primarily affects young adults. A unique risk factor profile and plurality of presenting features make it an elusive diagnosis unless a high index of suspicion is maintained. It comprises approximately 0.5% to 1% of all strokes, and widespread availability of magnetic resonance imaging has made recognition easier. The International Study on Cerebral Vein and Dural Sinus Thrombosis is the largest prospective, multinational, observational study of patients with CVT to date, including 624 consecutive patients with symptomatic CVT at 89 centers between May ...
Source: JAMA Neurology - March 15, 2016 Category: Neurology Source Type: research

Thrombus Length Estimation on Delayed Gadolinium-Enhanced T1 Clinical Sciences
Conclusions— The dGE-T1, obtained by simply adjusting scanning order in multimodal magnetic resonance imaging protocol, is a useful tool for thrombus length estimation and middle cerebral artery recanalization prediction after IVT.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Yan, S., Chen, Q., Xu, M., Sun, J., Liebeskind, D. S., Lou, M. Tags: Angiography, Ischemic Stroke Clinical Sciences Source Type: research

Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke? Brief Reports
Conclusions— b1000–b0 mismatch may identify patients with ischemic stroke of the within 4.5 hours of onset with high positive predictive value, perhaps constituting an alternative imaging tissue clock.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Geraldo, A. F., Berner, L.-P., Haesebaert, J., Chabrol, A., Cho, T.-H., Derex, L., Hermier, M., Louis-Tisserand, G., Chamard, L., Klaerke Mikkelsen, I., Ribe, L., Ostergaard, L., Hjort, N., Pedraza, S., Thomalla, G., Baron, J.-C., Nighoghossian, N., Berth Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Brief Reports Source Type: research

Early Detection and Quantification of Cerebral Venous Thrombosis by Magnetic Resonance Black-Blood Thrombus Imaging Clinical Sciences
Conclusions— The current findings support that with effectively suppressed blood signal, MRBTI allows selective visualization of thrombus as opposed to indirect detection of venous flow perturbation and can be used as a promising first-line diagnostic imaging tool.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Yang, Q., Duan, J., Fan, Z., Qu, X., Xie, Y., Nguyen, C., Du, X., Bi, X., Li, K., Ji, X., Li, D. Tags: Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Imaging Characteristics of Growing and Ruptured Vertebrobasilar Non-Saccular and Dolichoectatic Aneurysms Clinical Sciences
Conclusions— Vertebrobasilar, nonsaccular, and dolichoectatic aneurysms are associated with a poor natural history with high growth and rupture rates. Further research is needed to determine the best treatments for this disease.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Nasr, D. M., Brinjikji, W., Rouchaud, A., Kadirvel, R., Flemming, K. D., Kallmes, D. F. Tags: Risk Factors, Magnetic Resonance Imaging (MRI), Aneurysm Clinical Sciences Source Type: research

Antidepressant Use Is Associated With an Increased Risk of Developing Microbleeds Brief Reports
Conclusions— Antidepressant use was associated with an increased risk of developing microbleeds. Our results may support findings from previous clinical studies about increased intracranial and extracranial bleeding risk in antidepressant users.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Akoudad, S., Aarts, N., Noordam, R., Ikram, M. A., Tiemeier, H., Hofman, A., Stricker, B. H., Vernooij, M. W., Visser, L. E. Tags: Epidemiology, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research

Short-lived middle cerebral artery stenosis and crime atheroma.
CONCLUSION: Intracranial non-stenotic atheroma is a potential cause of a stroke. Our observation support HR-MRI as a tool for the etiology evaluation in young patients with cryptogenic stroke. PMID: 24458856 [PubMed - indexed for MEDLINE]
Source: Acta Neurologica Taiwanica - December 12, 2015 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Bilateral Paramedian Thalamic Infarction
Conclusions: Clinical presentation and imaging patterns described in this group of patients were similar to published data. High level of suspicion based on clinical and imaging findings is essential for early diagnosis of this rare condition. None of our patients had an early diagnosis of acute ischemic stroke and received proper thrombolytic treatment.
Source: The Neurologist - November 1, 2015 Category: Neurology Tags: Case Report/Case Series Source Type: research

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