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Condition: Thrombosis
Infectious Disease: SARS
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Total 301 results found since Jan 2013.
Interpretation of myocardial injury subtypes in COVID-19 disease per fourth version of universal definition of myocardial infarction
Conclusions: Objective description of myocardial injury according to the 4th UDMI in current COVID-19 pandemic is crucial in order to discriminate patients with acute myocardial infarction and acute, chronic or incident myocardial injury.PMID:33998352 | DOI:10.1080/1354750X.2021.1921031
Source: Biomarkers - May 17, 2021 Category: Research Authors: Christian Salbach Matthias Mueller-Hennessen Moritz Biener Kiril Stoyanov Michael Preusch Lars Kihm Uta Merle Paul Schnitzler Hugo A Katus Evangelos Giannitsis Source Type: research
Cerebral Venous Thrombosis after BNT162b2 mRNA SARS ‑CoV‑2 vaccine
We report two cases of cerebral venous thrombosis, shortly after administration of mRNA vaccine. In both patients, there was no evidence of thrombocytopenia or antiplatelet antibodies, and alternative causes for cerebral venous thrombosis were found.
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2021 Category: Neurology Authors: Leonor Dias, Ricardo Soares-dos-Reis, Jo ão Meira, Diana Ferrão, Pedro Ribeirinho Soares, Ana Pastor, Guilherme Gama, Luísa Fonseca, Vítor Fagundes, Marta Carvalho Source Type: research
Neurological complications in pediatric patients with SARS-CoV-2 infection: a systematic review of the literature
ConclusionsOur research highlights the large range of neurological manifestations and their presumed pathogenic pathways associated with SARS-CoV-2 infection in children. Nervous system involvement could be isolated, developing during COVID-19 or after its recovery, or arise in the context of a MIS-C. The most reported neurological manifestations are cerebrovascular accidents, reversible splenial lesions, GBS, benign intracranial hypertension, meningoencephalitis; ADEM is also a possible complication, as we observed in our patient. Further studies are required to investigate all the neurological complications of SARS-CoV-2...
Source: Italian Journal of Pediatrics - June 2, 2021 Category: Pediatrics Source Type: research
Pathogenic lipid-binding antiphospholipid antibodies are associated with severity of COVID-19
CONCLUSIONS: COVID-19 patients rapidly expand B1a cells secreting pathogenic lipid-binding aPL with broad thrombotic and inflammatory effects. The association with markers of inflammation and coagulation, clinical severity and mortality suggests a causal role of aPL in COVID-19 associated coagulopathy.PMID:34242469 | DOI:10.1111/jth.15455
Source: Thrombosis and Haemostasis - July 9, 2021 Category: Hematology Authors: Anne Hollerbach Nadine M üller-Calleja Denise Pedrosa Antje Canisius Martin F Sprinzl Tanja Falter Heidi Rossmann Marc Bodenstein Christian Werner Ingo Sagoschen Thomas M ünzel Oliver Schreiner Visvakanth Sivanathan Michael Reuter Johannes Niermann Pete Source Type: research
Cerebral Venous Thrombosis after BNT162b2 mRNA SARS-CoV-2 vaccine
We report two cases of cerebral venous thrombosis, shortly after administration of mRNA vaccine. In both patients, there was no evidence of thrombocytopenia or antiplatelet antibodies, and alternative causes for cerebral venous thrombosis were found.
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2021 Category: Neurology Authors: Leonor Dias, Ricardo Soares-dos-Reis, Jo ão Meira, Diana Ferrão, Pedro Ribeirinho Soares, Ana Pastor, Guilherme Gama, Luísa Fonseca, Vítor Fagundes, Marta Carvalho Source Type: research
Complement dysregulation is associated with severe COVID-19 illness
Haematologica. 2021 Jul 22. doi: 10.3324/haematol.2021.279155. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may manifest as thrombosis, stroke, renal failure, myocardial infarction, and thrombocytopenia, reminiscent of other complement-mediated diseases. Multiple clinical and preclinical studies have implicated complement in the pathogenesis of COVID-19 illness. We previously found that the SARS-CoV-2 spike protein activates the alternative pathway of complement (APC) in vitro through interfering with the function of complement factor H, a key negative regulator of APC. Here, w...
Source: Haematologica - July 22, 2021 Category: Hematology Authors: Jia Yu Gloria F Gerber Hang Chen Xuan Yuan Shruti Chaturvedi Evan M Braunstein Robert A Brodsky Source Type: research
Acute limb ischemia among patients with covid-19 infection
SARS-CoV-2 infection has been associated with thrombotic complications such as deep vein thrombosis or stroke. Recently, numerous cases of acute limb ischemia (ALI) have been reported although pooled data are lacking.
Source: Journal of Vascular Surgery - August 11, 2021 Category: Surgery Authors: George Galyfos, Argiri Sianou, Maximos Frountzas, Kotsarinis Vasilios, Dimitrios Vouros, Charis Theodoropoulos, Victoria Michalopoulou, Frangiska Sigala, Konstantinos Filis Source Type: research
Adverse Cardiovascular Effects of Anti-COVID-19 Drugs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly high in patients with cardiovascular diseases. In addition, COVID-19 patients with preexisting cardiovascular comorbidities have a higher risk of death. Main cardiovascular complications of COVID-19 are myocardial infarction, myocarditis, acute myocardial injury, arrhythmias, heart failure, stroke, and venous thromboembolism. Therapeutic interventions in terms of drugs for COVID-19 have many cardiac adverse effects. Here, we review the relative the...
Source: Frontiers in Pharmacology - August 25, 2021 Category: Drugs & Pharmacology Source Type: research
A case-based systematic review on the SARS-COVID-2-associated cerebrovascular diseases and the possible virus routes of entry
AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sparked a global pandemic that continues to affect various facets of human existence. Many sources reported virus-induced acute cerebrovascular disorders. Systematically, this paper reviews the case studies of COVID-19-related acute cerebrovascular diseases such as ischaemic stroke, intracerebral hemorrhage, and cerebral sinus thrombosis. We also spoke about how SARS-CoV-2 can infect the brain and trigger the aforementioned disorders. We stated that SARS-CoV-2 neuroinvasion and BBB dysfunction could cause the observed disorders; however, further research ...
Source: Journal of NeuroVirology - September 21, 2021 Category: Neurology Source Type: research
Platelets and COVID-19
Hamostaseologie. 2021 Oct;41(5):379-385. doi: 10.1055/a-1581-4355. Epub 2021 Oct 25.ABSTRACTIn 2019 first reports about a new human coronavirus emerged, which causes common cold symptoms as well as acute respiratory distress syndrome. The virus was identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe thrombotic events including deep vein thrombosis, pulmonary embolism, and microthrombi emerged as additional symptoms. Heart failure, myocardial infarction, myocarditis, and stroke have also been observed. As main mediator of thrombus formation, platelets became one of the key aspects in SARS-C...
Source: Hamostaseologie - October 25, 2021 Category: Hematology Authors: Anne-Katrin Rohlfing Dominik Rath Tobias Geisler Meinrad Gawaz Source Type: research
