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Condition: Thrombosis
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Total 178 results found since Jan 2013.

Microwave-Based Stroke Diagnosis Making Global Prehospital Thrombolytic Treatment Possible
Here, we present two different brain diagnostic devices based on microwave technology and the associated two first proof-of-principle measurements that show that the systems can differentiate hemorrhagic from ischemic stroke in acute stroke patients, as well as differentiate hemorrhagic patients from healthy volunteers. The system was based on microwave scattering measurements with an antenna system worn on the head. Measurement data were analyzed with a machine-learning algorithm that is based on training using data from patients with a known condition. Computer tomography images were used as reference. The detection meth...
Source: IEEE Transactions on Biomedical Engineering - October 17, 2014 Category: Biomedical Engineering Source Type: research

A cluster-randomised quality improvement study to improve two inpatient stroke quality indicators
Conclusion Quality improvement training was associated with early DVT improvement, but the effect was not sustained over time and was not seen with dysphagia screening. External quality improvement programmes may quickly boost performance but their effect may vary by indicator and may not sustain over time.
Source: Quality and Safety in Health Care - March 17, 2016 Category: Health Management Authors: Williams, L., Daggett, V., Slaven, J. E., Yu, Z., Sager, D., Myers, J., Plue, L., Woodward-Hagg, H., Damush, T. M. Tags: Original research Source Type: research

Dissection extending from extra- to intracranial arteries: A case report of progressive ischemic stroke
We reported a rare case of 33-year-old patient with progressive ischemic stroke due to dissection from an intimal tear in the right proximal internal carotid artery to distal middle cerebral artery. Diagnoses: 3D fat-saturated T1 VISTA imaging, owing to its comprehensive neck and head coverage, high spatial resolution, enables the reader to have several sections with good contrast covering the dissected arterial segment, even in the rare dissection involving extra- and intra-cranial arteries referred in this article. Interventions: Clopidogrel 75mg daily was prescribed, also the patient was given rehabilitation training....
Source: Medicine - May 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Predictive value of admission neutrophil/lymphocyte ratio in symptomatic intracranial hemorrhage after stroke thrombolysis
ConclusionFor predicting SICH, NLR did not provide strong specificity and sensitivity. A precise cut-off value could not be found to predict the hemorrhagic transformation.
Source: Neurological Sciences - May 21, 2021 Category: Neurology Source Type: research

Evaluation of a multicomponent intervention to shorten thrombolytic door-to-needle time in stroke patients in China (MISSION): A cluster-randomized controlled trial
ConclusionsThe teleconference-delivered PEITEM intervention resulted in a moderate but clinically relevant shorter DNT and better functional outcome in AIS patients receiving IVT. Trial registrationClinicaltrials.gov NCT03317639.
Source: PLoS Medicine - July 5, 2022 Category: Internal Medicine Authors: Wansi Zhong Source Type: research

The clot thickens —enhanced integration of stroke and thrombosis training
AbstractThere is significant overlap between knowledge and its clinical application in stroke and thrombosis& vascular medicine. Formal integration of training is, however, not standard. After the hyperacute phase of management, personalized medical decisions are often needed regarding antithrombotics and anticoagulants that leverage clinical practice parameters from both disciplines with a unique emphasis on minimizing neurologic treatment complications. We completed an ad hoc survey of adult thrombosis fellowships at several North American centers. We discovered that direct integration of training programs is not pre...
Source: Journal of Thrombosis and Thrombolysis - July 7, 2021 Category: Hematology Source Type: research

P81 Novel synthetic clot analogs for in-vitro stroke modelling
ConclusionSelected synthetic clots can successfully be implemented in an in-vitro training environment of mechanical thrombectomy. The clots’ different properties might serve to mimic fibrin-rich and red blood cell human thrombi.ReferencesNadine Wortmann, Thomas Andersek, Helena Guerreiro, et al. Development of Synthetic Thrombus Models to Simulate Stroke Treatment in a Physical Neurointerventional Training Model, All Life 2022;15:1, 283–301, DOI:10.1080/26895293.2022.2046181Spallek J, Kuhl J, Wortmann N, et al. Design for Mass Adaptation of the Neurointerventional Training Model Hannes with Patient-specific An...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guerreiro, H., Wortmann, N., Andersek, T., Ngo, T., Frölich, A., Krause, D., Fiehler, J., Kyselyova, A., Flottmann, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Internal carotid artery dissection and delayed stroke following rugby tackle - a case report
This report will offer a unique and interesting insight into the patient's perspective of this injury – both at the time the actual stroke occurred and his subsequent rehabilitation journey. It will also discuss that whilst much publicity and training is offered around the assessment and management of head injuries and/or concussion, the possible intracerebral consequence of neck trauma sustained in contact sports seems to be less well publicised. This mechanism of injury should be considered in the emergency department as in this case the ‘typical clinical presentation’ of an extradural haematoma turned ...
Source: British Journal of Sports Medicine - October 31, 2016 Category: Sports Medicine Authors: Cowlin, D., Dickinson, M., Sultan, S. Tags: Poster presentations Source Type: research

Venous Thromboembolism Research Priorities: A Scientific Statement From the American Heart Association and the International Society on Thrombosis and Haemostasis.
rsing; Council on Clinical Cardiology; Council on Epidemiology and Prevention; and the International Society on Thrombosis and Haemostasis Abstract Venous thromboembolism is a major cause of morbidity and mortality. The impact of the US Surgeon General's The Surgeon General's Call to Action to Prevent Deep Vein Thrombosis and Pulmonary Embolism in 2008 has been lower than expected given the public health impact of this disease. This scientific statement highlights future research priorities in venous thromboembolism, developed by experts and a crowdsourcing survey across 16 scientific organizations. At the fundame...
Source: Circulation - August 10, 2020 Category: Cardiology Authors: Cushman M, Barnes GD, Creager MA, Diaz JA, Henke PK, Machlus KR, Nieman MT, Wolberg AS, American Heart Association Council on Peripheral Vascular Disease; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Stroke N Tags: Circulation Source Type: research

P74 Keep it simple: MAC (Manual Aspiration with Contrast) technique for the endovascular management of acute ischemic stroke (LVO & MVO)
We report a prospectively collected clinical experience with a simple technique: MAC (Manual Aspiration Contrast Enhancement) as the primary method for vessel recanalization.Gently contrast injection while the aspiration catheter is advancedto the thrombus and subsequentlycreating a closed-loop system with the contrast column within the cathetercan result in better visualization during the aspiration, thus improving the FPEavoiding clot fragmentation, multiple passes and blind movements of catheter by a single operator.Methods47 prospectively patients with ELVO and 3 cases of middle vessel occlusion (MVO) at four instituti...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Pabon, B., Torres, V., Patino, M., Pelaez, F., Mutis, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Effects of task-specific rehabilitation training on tau modification in rat with photothrombotic cortical ischemic damage
Publication date: September 2017 Source:Neurochemistry International, Volume 108 Author(s): Kyung-Lim Joa, Sohee Moon, Ji-Hye Kim, Dong Wun Shin, Kyoung-Hee Lee, Seon Jung, Myeong-Ok Kim, Chang-Hwan Kim, Han-Young Jung, Ju-Hee Kang Although stroke elicits progressive cognitive decline and is a leading cause of dementia, molecular interplay between stroke and Alzheimer's disease (AD) pathology has not been fully elucidated. Furthermore, studies on the effects of post-stroke rehabilitation on AD pathology are limited. We evaluated the acute effect of stroke on tau modification, and the molecular effects of task-specific tra...
Source: Neurochemistry International - July 13, 2017 Category: Neuroscience Source Type: research

Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

Safety and long term effects on gait of hemiplegic patients in equino varus foot deformity surgical correction followed by immediate rehabilitation. A prospective observational study.
CONCLUSIONS: The ERT protocol with immediate rehabilitation starting on the first day after surgical correction was safe and effective in providing a long-term correction of EVFD. Ankle dorsiflexion improved both in stance and swing, allowing for a significative improvement in walking speed. CLINICAL REHABILITATION IMPACT: FSER can be considered an encouraging approach in the management of EVFD, with durable results. PMID: 30156087 [PubMed - as supplied by publisher]
Source: European Journal of Physical and Rehabilitation Medicine - August 27, 2018 Category: Rehabilitation Authors: Giannotti E, Merlo A, Zerbinati P, Prati P, Masiero S, Mazzoli D Tags: Eur J Phys Rehabil Med Source Type: research

A Copernican Approach to Brain Advancement: The Paradigm of Allostatic Orchestration
The objective of this presentation is to explore historical, scientific, interventional, and other differences between the two paradigms, so that innovators, researchers, practitioners, policy-makers, patients, end-users, and others can gain clarity with respect to both the explicit and implicit assumptions associated with brain advancement agendas of any kind. Over the course of three decades, a series of brain-centric, evolution-inspired insights have been articulated with increasing refinement, as principles of allostasis (Sterling and Eyer, 1988; Sterling, 2004, 2012, 2014). Allostasis recognizes that the role of the ...
Source: Frontiers in Human Neuroscience - April 25, 2019 Category: Neuroscience Source Type: research

The Oversimplification of Cholesterol Testing Can Be Deadly
Early every year, countless Americans embark on a new fitness regime. They go for a physical and maybe for a blood test to measure cholesterol levels. After a clean bill of health, they might train to run a 10K, a marathon or even an Iron man. But what if those tests do not provide a complete picture of your health? What if you are on the verge of a heart attack and have no idea? Before 30, when the human body is at its peak, it can take the strain of being pushed to the limit. As we age, however, cellular changes and the expression of genetic predispositions can dramatically alter our health. Conventional medical tests a...
Source: Healthy Living - The Huffington Post - April 6, 2016 Category: Consumer Health News Source Type: news