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Risk of Stroke, Myocardial Infarction, Deep Vein Thrombosis, Pulmonary Embolism, and Death after Retinal Vein Occlusion
To examine rates of stroke, myocardial infarction (MI), deep vein thrombosis (DVT), pulmonary embolism (PE), and death in patients after retinal vein occlusion (RVO) compared to controls.
Source: American Journal of Ophthalmology - September 1, 2023 Category: Opthalmology Authors: Karen M. Wai, Cassie A. Ludwig, Euna Koo, Ravi Parikh, Prithvi Mruthyunjaya, Ehsan Rahimy Tags: Original Articles Source Type: research

Progressive Central Artery Occlusion, Ophthalmic Artery Occlusion, and Hemispheric Intracranial Thrombosis after COVID-19 mRNA Vaccine Application: Case Report
Thromboembolic events as a result of COVID-19 mRNA vaccination are a rare, though life-threatening complication. In this case report, we describe a 40-year-old female patient who developed central retinal artery and ophthalmic artery occlusion progressing to intracranial thrombosis 3 weeks after vaccination with the Pfizer-BioNTech COVID-19 vaccine. Initially, she presented with progressive acute and painless unilateral vision loss in her left eye. Dilated fundoscopy of left eye showed macular whitening with sparing of the area of cilioretinal artery distribution. Labs revealed a normal erythrocyte sedimentation rate, C-re...
Source: Case Reports in Ophthalmology - April 18, 2023 Category: Opthalmology Source Type: research

Role of the ABO blood groups as a risk factor for retinal vein occlusion
In this study we investigated (i) an association between blood group and the presence of RVO and (ii) whether this association correlated to other RVO risk factors. Methods We included 485 RVO patients and 295 control subjects who were recruited in this case-control study. We determined ABO genotypes rs8176719 as a marker for the O allele and rs8176746 for the B allele by polymerase chain reaction. Results We did not find an association between ABO blood gr oup and the presence of RVO. In detail, the proportion of ABO blood groups was similar among RVO patients and control subjects (p=0.527). In a logistic regression, ...
Source: Ophthalmic Research - September 1, 2022 Category: Opthalmology Source Type: research

Nonaretritic central retinal artery occlusion as marker for the generalized vascular risk
CONCLUSION: Although cardiovascular diseases are already known in most patients at the onset of an RAO, further risk factors are detected in almost 80% of cases. Therefore, and because of the high risk for recurrent thromboembolism, immediate and standardized neurological internal medical clarification of the cause is urgently recommended after an acute RAO in the context of an inpatient stay.PMID:34350493 | DOI:10.1007/s00347-021-01466-6
Source: Der Ophthalmologe - August 5, 2021 Category: Opthalmology Authors: Nicolas Feltgen Jan Liman Maximilian Schultheiss Martin S Spitzer Amelie Pielen Sven Poli Source Type: research

Serum levels of antibodies against oxidation-specific epitopes are decreased in patients with retinal vein occlusion
Conclusion: These prospective data show that antibodies against oxidation-specific epitope are lower in patients with RVO compared with control patients and support the concept that oxidative stress and inflammation play key roles in the development and subsequent complications in RVO.
Source: RETINA - May 27, 2021 Category: Opthalmology Tags: Original Study Source Type: research

Thrombolysis for Central Retinal Artery Occlusion in 2020: Time Is Vision!
Conclusions: In 2020, nonarteritic CRAO patients should theoretically receive the same thrombolytic therapies, in the same time window, as patients with acute cerebral ischemia. Eye stroke and teleeye stroke code encounters must include an expert ophthalmologic evaluation to confirm the correct diagnosis and to evaluate for ocular signs that may help guide IV tPA administration or IA management. Future research should focus on developing feasible retinal penumbra imaging studies that, similar to cerebral tissue viability or perfusion imaging, can be incorporated into the thrombolysis decision-making algorithm.
Source: Journal of Neuro-Ophthalmology - August 25, 2020 Category: Opthalmology Tags: Disease of the Year: Cerebrovascular Disorders Source Type: research

Stroke Risk and Risk Factors in Patients With Central Retinal Artery Occlusion
We read with interest the recently published article1 and commentaries2,3 on the stroke risk and acute management of patients with central retinal artery occlusion (CRAO). As emphasized by Lavin and associates,1 CRAO patients have a high risk of stroke and cardiovascular events. In Lavin and associates' series of 103 patients with acute CRAO seen within 7  days of onset of visual loss, 37.3% of the 67 patients with brain magnetic resonance imaging had coincident acute strokes, 36.7% of patients had severe carotid disease (greater than 70% stenosis, dissection, or intra-arterial thrombus), 33% presented with hypertensive...
Source: American Journal of Ophthalmology - December 19, 2018 Category: Opthalmology Authors: Valerie Biousse, Nancy J. Newman Tags: Correspondence Source Type: research

Transient monocular blindness: Vascular causes and differential diagnoses.
Authors: Bidot S, Biotti D Abstract Transient monocular blindness is an acute episode of ischemic origin in which one eye has profound visual loss, followed by full recovery within one hour. Transient monocular blindness most often occurs in the setting of retinal ischemia secondary to carotid embolism, but other mechanisms have been reported, including thrombosis (most often in the setting of giant cell arteritis), hemodynamic disorders (secondary to severe carotid stenosis) or vasospasm. Transient monocular blindness is considered a transient ischemic attack originating in the carotid arteries and must benefit fr...
Source: Journal Francais d Ophtalmologie - May 20, 2018 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Transient monocular blindness: Vascular causes and differential diagnoses.
Authors: Bidot S, Biotti D Abstract Transient monocular blindness is an acute episode of ischemic origin in which one eye has profound visual loss, followed by full recovery within one hour. Transient monocular blindness most often occurs in the setting of retinal ischemia secondary to carotid embolism, but other mechanisms have been reported, including thrombosis (most often in the setting of giant cell arteritis), hemodynamic disorders (secondary to severe carotid stenosis), or vasospasm. Transient monocular blindness is considered a transient ischemic attack originating in the carotid arteries, and must be manag...
Source: Journal Francais d Ophtalmologie - April 22, 2018 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research

Retinal Artery Occlusions.
Authors: Lang GE, Lang SJ Abstract Retinal artery occlusions are acute vascular diseases. Very often they are caused by an embolisation. Rarely a thrombosis is caused by an arteriitis. In the acute phase diagnosis in most of the cases can be made by ophthalmoscopy due to the whitish retinal edema and in central retinal artery occlusion the cherry red spot. Difficulties in making the diagnosis can occur in the chronic stage, especially after reperfusion of the retinal vessels, when the fundus colour returned to normal again. Several diagnostic procedures help to make the diagnosis. Unfortunately there is no generall...
Source: Klinische Monatsblatter fur Augenheilkunde - November 21, 2017 Category: Opthalmology Tags: Klin Monbl Augenheilkd Source Type: research