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Source: Journal of Thrombosis and Haemostasis
Condition: Thrombosis
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Total 137 results found since Jan 2013.
Prothrombin Complex Concentrate (PCC) for Non‐Vitamin K Oral Anticoagulant (NOAC) reversal: Good enough for now?
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 1, 2014 Category: Hematology Authors: Mike Makris Tags: Commentary Source Type: research
Comparing Mortality in Patients with Atrial Fibrillation who are Receiving a Direct Oral Anticoagulant or Warfarin: A Meta‐analysis of Randomized Trials
ConclusionCompared with warfarin therapy for stroke prevention in patients with AF, DOACs significantly reduce all‐cause mortality, vascular mortality and bleeding mortality. This mortality benefit appears to be driven by the reduction in vascular‐ and bleeding‐related mortality which, in turn, may be related to the reduction in intracranial bleeding.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 1, 2014 Category: Hematology Authors: A. Liew, M. O'Donnell, J. Douketis Tags: Brief Report ‐ Coagulation Source Type: research
Antigen levels of coagulation factor XII, coagulation factor XI and prekallikrein, and the risk of myocardial infarction and ischemic stroke in young women
ConclusionIncreased levels of FXI antigen were associated with an increase in IS risk, whereas they showed only a marginal association with MI risk. FXII antigen and PK antigen levels were not substantially associated with MI risk and IS risk.
Source: Journal of Thrombosis and Haemostasis - May 22, 2014 Category: Hematology Authors: B. Siegerink, F. R. Rosendaal, A. Algra Tags: Original Article Source Type: research
ABO blood type and stroke risk: the REasons for Geographic And Racial Differences in Stroke Study
ConclusionBlood type AB is associated with an increased risk of stroke that is not attenuated by conventional stroke risk factors, and factor VIII levels were associated with 60% of the association. While blood type AB is rare in the US population, it is a significant stroke risk factor and may play an important role in stroke risk in these individuals.
Source: Journal of Thrombosis and Haemostasis - April 11, 2014 Category: Hematology Authors: N. A. Zakai, S. E. Judd, K. Alexander, L. A. McClure, B. M. Kissela, G. Howard, M. Cushman Tags: Original Article Source Type: research
Thrombolytic therapy or surgery for valve prosthesis thrombosis: systematic review and meta‐analysis
ConclusionMortality in patients treated by thrombolytic therapy for valve prosthesis thrombosis is significantly lower than in patients treated surgically. As we cannot yet ascertain whether this difference is due to the treatment alone, more studies now are necessary to further clarify these findings.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 2, 2014 Category: Hematology Authors: F. M. Castilho, M. R. Sousa, A. L. P. Mendonça, A. L. P. Ribeiro, F. M. Cáceres‐Lóriga Tags: Original Article ‐ Cardiovascular Medicine Source Type: research
Circulating desphospho‐uncarboxylated matrix Gla protein and the risk of coronary heart disease and stroke
This study could not confirm that high dp‐ucMGP concentrations, reflecting a poor vitamin K status, are associated with increased CHD or stroke risk in the general population.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 1, 2014 Category: Hematology Authors: Geertje W. Dalmeijer, Yvonne T. Schouw, Elke J. Magdeleyns, Cees Vermeer, W.M. Monique Verschuren, Jolanda M.A. Boer, Joline W.J. Beulens Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research
It's not about sex
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Source: Journal of Thrombosis and Haemostasis - March 15, 2014 Category: Hematology Authors: M. Greaves Tags: Commentary Source Type: research
Report of the Subcommittee on Control of Anticoagulation on the determination of the anticoagulant effects of apixaban: communication from the SSC of the ISTH
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - March 5, 2014 Category: Hematology Authors: Job Harenberg, Shanshan Du, Christel Weiss, Roland Krämer, Debra Hoppensteadt, Jeanine Walenga, Tags: Recommendations and Guidelines Source Type: research
Comparison of idrabiotaparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: the Borealis‐AF study
ConclusionIf anything, despite its early termination the idrabiotaparinux regimen studied suggested a comparable efficacy to dose‐adjusted warfarin, with a lower bleeding risk.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - March 5, 2014 Category: Hematology Authors: H.R. Buller, J. Halperin, G.J. Hankey, G. Pillion, M.H. Prins, G.E. Raskob Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research
Associations of Pentraxin 3 with Cardiovascular Disease: The Multi‐Ethnic Study of Atherosclerosis
ConclusionsIn these apparently healthy adults, PTX3 was associated with CVD risk factors, subclinical CVD, CAC and incident coronary heart disease events independent of CRP and CVD risk factors. These results support the hypothesis that PTX3 reflects different aspects of inflammation than CRP and may provide additional insight into the development and progression of atherosclerosis.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - March 1, 2014 Category: Hematology Authors: Nancy Swords Jenny, Roger S. Blumenthal, Richard A. Kronmal, Jerome I. Rotter, David S. Siscovick, Bruce M. Psaty Tags: Original Article ‐ Vascular Biology Source Type: research
Improving Prediction of Recanalization in Acute Large Vessel Occlusive Stroke
ConclusionsAcute endovascular treatment is the single most important factor promoting recanalization in acute ischemic stroke. Presence of extracranial vessel stenosis or occlusion decreases recanalization rates. In patients with intracranial occlusions, higher NIHSS and ASPECTS and normal vigilance facilitate recanalization. Integration in treatment algorithms could influence recanalization strategies in individual patients.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - March 1, 2014 Category: Hematology Authors: Peter Vanacker, Dimitris Lambrou, Ashraf Eskandari, Philippe Maeder, Reto Meuli, George Ntaios, Patrik Michel Tags: Original Article ‐ Cardiovascular Medicine Source Type: research
Antigen levels of coagulation Factor XII, XI, prekallikrein and the risk of myocardial infarction and ischemic stroke in young women
ConclusionIncreased antigen levels of FXI were associated with an increase in ischemic stroke risk, whereas the risk of myocardial infarction is only marginally associated. FXII:ag and PK:ag levels were not substantially associated with MI and IS risk.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - February 21, 2014 Category: Hematology Authors: Bob Siegerink, Frits R Rosendaal, Ale Algra Tags: Original Article ‐ Cardiovascular Medicine Source Type: research
The DRY Motif at Work: The P2Y12 Receptor Case
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - February 1, 2014 Category: Hematology Authors: G. Enrico Rovati, Valérie Capra Tags: Commentary Source Type: research
ABO Blood Type and Stroke Risk: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study
ConclusionBlood type AB is associated with an increased risk of stroke that is not attenuated by conventional stroke risk factors and factor VIII levels were associated with 60% of the association. While blood type AB is rare in the U.S. population, it is a significant stroke risk factor and may play an important role in stroke risk in these individuals.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - January 21, 2014 Category: Hematology Authors: Neil A. Zakai, Suzanne E. Judd, Kristine Alexander, Leslie A. McClure, Brett M. Kissela, George Howard, Mary Cushman Tags: Original Article ‐ Vascular Biology Source Type: research
Lack of secondary microthrombosis after thrombin‐induced stroke in mice and non‐human primates
ConclusionsOur data demonstrates that secondary microthrombosis does not occur after thrombin‐induced stroke. In view of that, the pathophysiological roles of hematologic players promoting or protecting from secondary microthrombosis (such as Factor XII, von Willebrand Factor, T‐cells…) deserve to be reevaluated in non‐TMVO stroke models.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - December 16, 2013 Category: Hematology Authors: Maxime Gauberti, Sara Martinez Lizarrondo, Cyrille Orset, Denis Vivien Tags: Brief Report ‐ Vascular Biology Source Type: research
