Lack of secondary microthrombosis after thrombin‐induced stroke in mice and non‐human primates

ConclusionsOur data demonstrates that secondary microthrombosis does not occur after thrombin‐induced stroke. In view of that, the pathophysiological roles of hematologic players promoting or protecting from secondary microthrombosis (such as Factor XII, von Willebrand Factor, T‐cells…) deserve to be reevaluated in non‐TMVO stroke models.This article is protected by copyright. All rights reserved.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1111%2Fjth.12487

Source: Journal of Thrombosis and Haemostasis - December 16, 2013 Category: Hematology Authors: Maxime Gauberti, Sara Martinez Lizarrondo, Cyrille Orset, Denis Vivien Tags: Brief Report ‐ Vascular Biology Source Type: research