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Source: Journal of Thrombosis and Haemostasis
Condition: Thrombosis
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Total 137 results found since Jan 2013.
Hemostasis biomarkers and risk of sepsis: the REGARDS cohort
ConclusionBaseline fibrinogen, FIX and FXI levels are associated with future episodes of sepsis. Hemostasis biomarkers may provide targets for sepsis mitigation or prevention.
Source: Journal of Thrombosis and Haemostasis - September 22, 2016 Category: Hematology Authors: J. X. Moore, N. A. Zakai, M. Mahalingam, R. L. Griffin, M. R. Irvin, M. M. Safford, J. W. Baddley, H. E. Wang Tags: Original Article Source Type: research
Factor VII ‐activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation
ConclusionsFSAP deficiency causes an increase in CCL2 expression and CCL2‐mediated infiltration of leukocytes into the injured vessel, thereby promoting SMC proliferation and migration by the activation of leukocyte‐derived gelatinases. These results provide a possible explanation for the observed association of the loss‐of‐function MI‐SNP with vascular proliferative diseases.
Source: Journal of Thrombosis and Haemostasis - September 6, 2016 Category: Hematology Authors: J. ‐M. Daniel, C. A. Reichel, T. Schmidt‐Woell, J. Dutzmann, G. Zuchtriegel, F. Krombach, J. Herold, J. Bauersachs, D. G. Sedding, S. M. Kanse Tags: Original Article Source Type: research
Optimising stroke prevention in elderly patients with atrial fibrillation
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 24, 2016 Category: Hematology Authors: Gregory Y H Lip Tags: Commentary Source Type: research
Low ADAMTS ‐13 activity and the risk of coronary heart disease – a prospective cohort study: the Rotterdam Study
ConclusionsLow ADAMTS‐13 activity is associated with an increased risk of coronary heart disease in the elderly, independently of VWF and established cardiovascular risk factors.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - August 24, 2016 Category: Hematology Authors: M.A.H. Sonneveld, M. Kavousi, M.A. Ikram, A. Hofman, O.L. Rueda Ochoa, P.L. Turecek, O.H. Franco, F.W.G. Leebeek, M.P.M. de Maat Tags: Original Article ‐ Cardiovascular Medicine Source Type: research
Factor VII activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation
ConclusionsFSAP deficiency causes an increase in CCL2 expression and CCL2‐mediated infiltration of leukocytes into the injured vessel, thereby promoting SMC proliferation and migration by activation of leukocyte‐derived gelatinases. These results provide a possible explanation for the observed association of the loss‐of‐function MI‐SNP with vascular proliferative diseases.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - July 18, 2016 Category: Hematology Authors: Jan‐Marcus Daniel, Christoph A. Reichel, Thomas Schmidt‐Woell, Jochen Dutzmann, Gabriele Zuchtriegel, Fritz Krombach, Joerg Herold, Johann Bauersachs, Daniel G. Sedding, Sandip M. Kanse Tags: Original Article ‐ Vascular Biology Source Type: research
Benefits and Challenges of Going Abroad for Research or Clinical Training
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - July 17, 2016 Category: Hematology Authors: Nicoletta Riva, Mandy Lauw Tags: Early Career Series Source Type: research
Hemostasis Biomarkers and Risk of Sepsis: the REasons for Geographic And Racial Differences in Stroke (REGARDS) cohort
ConclusionBaseline fibrinogen, factor IX, and factor XI are associated with future episodes of sepsis. Hemostasis biomarkers may provide targets for sepsis mitigation or prevention.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 30, 2016 Category: Hematology Authors: Justin Xavier Moore, Neil A. Zakai, Mythreyi Mahalingam, Russell L. Griffin, Marguerite R. Irvin, Monika M. Safford, John W. Baddley, Henry E Wang Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research
The patterns of anticoagulation control and the risk of stroke, bleeding and mortality in patients with non‐valvular atrial fibrillation: comment
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 30, 2016 Category: Hematology Authors: Simon Mantha, Stephan Moll, Patrick Hilden, Sean Devlin, Adam Rose Tags: Letter ‐ to the Editor Source Type: research
A comparison of red blood cell transfusion utilization between anti ‐factor Xa and activated partial thromboplastin monitoring in patients receiving unfractionated heparin
ConclusionAnti‐Xa was associated with a significant reduction in RBC transfusions when compared to patients monitored by aPTT alone.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 30, 2016 Category: Hematology Authors: K.W. Belk, M. Laposata, C. Craver Tags: Original Article ‐ Clinical Haemostasis and Thrombosis Source Type: research
Plasminogen and stroke: more is better
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 29, 2016 Category: Hematology Authors: R. L. Medcalf Tags: Commentary Source Type: research
Physiologic Variations in Blood Plasminogen Levels Affect Outcomes after Acute Cerebral Thromboembolism in Mice: A Pathophysiologic Role for Microvascular Thrombosis
ConclusionsVariation in blood plasminogen levels, within the range seen in normal individuals, had marked effects on experimental ischemic brain injury. Higher plasminogen levels protected against ischemic brain injury, decreased blood‐brain barrier breakdown, matrix metalloproteinase‐9 expression and microvascular thrombosis. The protective effects of blood plasminogen appear to be mediated largely through reduction of microvascular thrombosis in the ischemic territory.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - May 31, 2016 Category: Hematology Authors: Satish Singh, Aiilyan K. Houng, Dong Wang, Guy L. Reed Tags: Original Article ‐ Fibrinolysis Source Type: research
Bleeding Risk Assessment in Atrial Fibrillation: Observations on the Use and Misuse of Bleeding Risk Scores
This article is protected by copyright. All rights reserved
Source: Journal of Thrombosis and Haemostasis - May 31, 2016 Category: Hematology Authors: Gregory Y H Lip, Deirdre A Lane Tags: Commentary Source Type: research
Management of direct oral anticoagulants in women of childbearing potential: guidance from the SSC of the ISTH
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 30, 2016 Category: Hematology Authors: Hannah Cohen, Deepa Jayakody Arachchillage, Saskia Middeldorp, Jan Beyer‐Westendorf, Rezan Abdul Kadir Tags: Recommendations and Guidelines Source Type: research
A Rabbit Model of Cerebral Microembolic Signals for Translational Research: Preclinical Validation for Aspirin and Clopidogrel
ConclusionsOur study demonstrated the successful establishment of the MES model in rabbits, which may provide translational value for MES and ischemic stroke research.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 30, 2016 Category: Hematology Authors: X Zhou, S Kurowski, W Wu, K Desai, L Chu, D E Gutstein, D Seiffert, X Wang Tags: Original Article ‐ Platelets Source Type: research
Impact of point‐of‐care international normalized ratio monitoring on quality of treatment with vitamin K antagonists in non‐self‐monitoring patients: a cohort study
ConclusionsAlthough associated with lower TTR, POC INR monitoring is a safe and effective alternative to laboratory INR monitoring in NSM patients on VKA.
Source: Journal of Thrombosis and Haemostasis - March 29, 2016 Category: Hematology Authors: J. S. Biedermann, N. Rein, A. M. H. P. Besselaar, P. N. Buhre, M. P. M. Maat, F. J. M. Meer, F. W. G. Leebeek, M. J. H. A. Kruip Tags: Original Article Source Type: research
