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Specialty: Endocrinology
Condition: Osteoporosis

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Total 17 results found since Jan 2013.

Utilization of screening and treatment for osteoporosis among stroke survivors
ConclusionsBoth BMD testing and osteoporosis treatment were underutilized among stroke survivors even though they had a higher chance of receiving both measures than non-stroke patients.
Source: Frontiers in Endocrinology - December 1, 2022 Category: Endocrinology Source Type: research

New insights into the comorbid conditions of Turner syndrome: results from a long-term monocentric cohort study
ConclusionsThis cohort study confirms the need for continuous, structured and multidisciplinary lifelong monitoring of TS, thus ensuring the early diagnosis of important comorbid conditions, including cancer, and their appropriate and timely treatment. In addition, these data highlight the need for the increased surveillance of specific types of cancer in TS, including thyroid carcinoma.
Source: Journal of Endocrinological Investigation - November 11, 2022 Category: Endocrinology Source Type: research

Heart failure and stroke risks in users of liothyronine with or without levothyroxine compared to levothyroxine alone: A propensity score matched analysis
CONCLUSIONS: The use of LT3 was associated with increased incidence of heart failure and stroke in patients with a longer duration of LT3 use and history of thyroid cancer. Therefore, clinicians should consider the risk of heart failure and stroke in thyroid cancer patients with long-term use of LT3. These findings require confirmation in other populations.PMID:35570696 | DOI:10.1089/thy.2021.0634
Source: Thyroid : official journal of the American Thyroid Association - May 16, 2022 Category: Endocrinology Authors: Wook Yi Bo Hyun Kim Mijin Kim Jinmi Kim Myungsoo Im Soree Ryang Eun Heui Kim Yun Kyung Jeon Sang Soo Kim In Joo Kim Source Type: research

Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study
Publication date: Available online 31 October 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Michael R McClung, Michelle L O'Donoghue, Socrates E Papapoulos, Henry Bone, Bente Langdahl, Kenneth G Saag, Ian R Reid, Douglas P Kiel, Ilaria Cavallari, Marc P Bonaca, Stephen D Wiviott, Tobias de Villiers, Xu Ling, Kurt Lippuner, Toshitaka Nakamura, Jean-Yves Reginster, Jose Adolfo Rodriguez-Portales, Christian Roux, José Zanchetta, Cristiano A F ZerbiniSummaryBackgroundOdanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining bone formation. Previous work has shown that odanacatib increases bone...
Source: The Lancet Diabetes and Endocrinology - November 2, 2019 Category: Endocrinology Source Type: research

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

Lower risk of osteoporosis in new stroke patients treated with statins
Patients diagnosed with a stroke and treated with statins may be at less risk of developing osteoporosis, according to research published in theJournal of Clinical Endocrinology& Metabolism.Neurology Advisor
Source: Society for Endocrinology - August 30, 2018 Category: Endocrinology Source Type: news

Statin use is associated with decreased osteoporosis and fracture risks in stroke patients.
Conclusions: Statin use is associated with decreased risks of osteoporosis, hip fracture, and vertebral fracture in stroke patients. PMID: 29982482 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - July 2, 2018 Category: Endocrinology Authors: Lin SM, Wang JH, Liang CC, Huang HK Tags: J Clin Endocrinol Metab Source Type: research

Acromegaly at diagnosis in 3173 patients from the Liege Acromegaly Survey (LAS) Database
In conclusion, this study of >3100 patients is the largest international acromegaly database and shows clinically relevant trends in the characteristics of acromegaly at diagnosis.
Source: Endocrine-Related Cancer - August 22, 2017 Category: Endocrinology Authors: Petrossians, P., Daly, A. F., Natchev, E., Maione, L., Blijdorp, K., Sahnoun-Fathallah, M., Auriemma, R., Diallo, A. M., Hulting, A.-L., Ferone, D., Hana, V., Filipponi, S., Sievers, C., Nogueira, C., Fajardo-Montanana, C., Carvalho, D., Hana, V., Stalla, Tags: Research Source Type: research

Benefits of calcium supplements may be outweighed by cardiovascular risks
A Norweigan study published in Osteoporosis International suggests that the bone-strength benefits of taking calcium and vitamin D supplements may be outweighted by an increased risk of heart attack and stroke. Science Daily
Source: Society for Endocrinology - May 16, 2016 Category: Endocrinology Source Type: news

Complications of Cushing's syndrome: state of the art
Publication date: Available online 10 May 2016 Source:The Lancet Diabetes & Endocrinology Author(s): Rosario Pivonello, Andrea M Isidori, Maria Cristina De Martino, John Newell-Price, Beverly M K Biller, Annamaria Colao Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities. These clinical complications include metabolic syndrome, consisting of systemic arterial hypertension, visceral obesity, impairment of glucose metaboli...
Source: The Lancet Diabetes and Endocrinology - May 11, 2016 Category: Endocrinology Source Type: research

Muscle-bone interactions: from experimental models to the clinic? A critical update
Publication date: Available online 23 October 2015 Source:Molecular and Cellular Endocrinology Author(s): Michaël R. Laurent, Vanessa Dubois, Frank Claessens, Sabine M.P. Verschueren, Dirk Vanderschueren, Evelien Gielen, Ferran Jardí Bone is a biomechanical tissue shaped by forces from muscles and gravitation. Simultaneous bone and muscle decay and dysfunction (osteosarcopenia or sarco-osteoporosis) is seen in ageing, numerous clinical situations including after stroke or paralysis, in neuromuscular dystrophies, glucocorticoid excess, or in association with vitamin D, growth hormone/insulin like growth factor or...
Source: Molecular and Cellular Endocrinology - October 24, 2015 Category: Endocrinology Source Type: research

Infertility etiologies are genetically and clinically linked with other diseases in single meta-diseases
The present review aims to ascertain whether different infertility etiologies share particular genes and/or molecular pathways with other pathologies and are associated with distinct and particular risks of later-life morbidity and mortality. In order to reach this aim, we use two different sources of information: (1) a public web server named DiseaseConnect (http://disease-connect.org) focused on the analysis of common genes and molecular mechanisms shared by diseases by integrating comprehensive omics and literature data; and (2) a literature search directed to find clinical comorbid relationships of infertility etiologi...
Source: Reproductive Biology and Endocrinology - April 15, 2015 Category: Endocrinology Authors: Juan TarínMiguel García-PérezToshio HamataniAntonio Cano Source Type: research