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Condition: Subarachnoid Hemorrhage
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Total 3336 results found since Jan 2013.
Cytochrome P450-derived eicosanoids in brain: From basic discovery to clinical translation
Adv Pharmacol. 2023;97:283-326. doi: 10.1016/bs.apha.2022.11.002. Epub 2023 Jan 11.ABSTRACTCytochrome P450 metabolism of arachidonic acid produces epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs). Both classes of eicosanoids play important and opposing roles in brain function and disease. EETs promote vasodilation and exhibit antiinflammatory and cytoprotective properties; their biological action is blunted by metabolism to less active diols by the enzyme soluble epoxide hydrolase (sEH). EETs levels are dysregulated in disease states, primarily due to increased activity of sEH. Inhibition of sEH is a prom...
Source: Advances in Pharmacology - May 26, 2023 Category: Drugs & Pharmacology Authors: Catherine M Davis Aseel H Ibrahim Nabil J Alkayed Source Type: research
Stroke burden and attributable risk factors in China, 1990 –2019
ConclusionThis study reinforced the findings of an increased stroke burden in China. Precise stroke prevention strategies are needed to reduce the disease burden of stroke.
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research
Sex and age effects on risk of non-traumatic subarachnoid hemorrhage: Retrospective cohort study of 124,234 cases using electronic health records
This study describes the antecedent characteristics of SAH patients, compares the risk of SAH between women and men, and explores if this changes with age.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2023 Category: Neurology Authors: Charlotte H Harrison, Maxime Taquet, Paul J Harrison, Peter J Watkinson, Matthew J Rowland Source Type: research
Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
Adv Sci (Weinh). 2023 May 21:e2301428. doi: 10.1002/advs.202301428. Online ahead of print.ABSTRACTSubarachnoid hemorrhage (SAH) is a devastating subtype of stroke with high mortality and disability rate. Meningeal lymphatic vessels (mLVs) are a newly discovered intracranial fluid transport system and are proven to drain extravasated erythrocytes from cerebrospinal fluid into deep cervical lymph nodes after SAH. However, many studies have reported that the structure and function of mLVs are injured in several central nervous system diseases. Whether SAH can cause mLVs injury and the underlying mechanism remain unclear. Here...
Source: Adv Data - May 22, 2023 Category: Epidemiology Authors: Xiaoyu Wang Anke Zhang Qian Yu Zelin Wang Junjie Wang Penglei Xu Yibo Liu Jianan Lu Jingwei Zheng Huaming Li Yangjian Qi Jiahao Zhang Yuanjian Fang Shenbin Xu Jingyi Zhou Kaikai Wang Sheng Chen Jianmin Zhang Source Type: research
COVID-19 and Cerebrovascular Disease
This article discusses the incidence of these cerebrovascular complications, risk factors, management strategies, prognosis and future research directions, as well as considerations in pregnancy-related cerebrovascular events in the setting of COVID-19. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Seminars in Neurology - May 22, 2023 Category: Neurology Authors: Catherine, Christina Veitinger, Julia Chou, Sherry H-Y. Tags: Review Article Source Type: research
Fulminant Extra- And Intracranial Arteriovenous Thrombosis And Non-aneurysmal Subarachnoid Hemorrhage Following COVID-19 Infection
CONCLUSION: A high degree of suspicion for COVID-19 induced coagulopathy leading to extensive non- aneurysmal, non-hemispheric SAH and malignant intracranial hypertension should be entertained. Our experience and previous reports on non-aneurysmal SAH in such patients show a poor prognosis.PMID:37198510
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Sunil V Furtado Nishchit Hegde Vinay M D Prabhu Source Type: research
