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Condition: Subarachnoid Hemorrhage

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Total 3336 results found since Jan 2013.

Response to: Aspirin and Subarachnoid Haemorrhage in the UK Biobank
Source: Translational Stroke Research - August 7, 2023 Category: Neurology Source Type: research

Assessment of rehabilitation following subarachnoid haemorrhage in China: findings from the Chinese Stroke Center Alliance
Rehabilitation improves functional recovery in subarachnoid hemorrhage (SAH) patients, and assessing patients for rehabilitation is the first step in this process. However, little is known about clinical pract...
Source: BMC Neurology - August 5, 2023 Category: Neurology Authors: Yi-Tong Chen, Mei-Ru Wu, Zi-Xiao Li, Hong-Qiu Gu, Qi Zhou, Dan-Dan Wang, Yong-Jun Wang and Xing-Quan  Zhao Tags: Research Source Type: research

LB-004 Novel saccular endovascular aneurysm lattice (SEAL device) pre-seal it early clinical feasibility trial: procedural, 24-hours, and 3-month safety and effectiveness independent core lab adjudicated outcomes
ConclusionThe final procedural, 24-hour, and 3-month follow-up results of the PRE-SEAL-IT trial demonstrated promising occlusion rates at post-procedural, 24-hour, and 3 months follow-up with no safety concerns.DisclosuresB. Pabón: None. V. Torres: None. S. Zaidi: None. H. Salahuddin: None. M. Patiño: None. F. Peláez: None. J. Mútis: None. M. Cardozo: None. A. Hussain: None. I. Lutfi: None. M. Ali: None. S. Ahmed: None. E. Pereira: None. A. Badruddin: None. K. Woodward: None. T. Wolfe: None. C. Langerford: None. B. Jankowitz: None. V. Costalat: None. D. Altschell: None. M. Kaffashi: None. O. Zaidat: None.
Source: Journal of NeuroInterventional Surgery - August 3, 2023 Category: Neurosurgery Authors: Pabon, B., Torres, V., Zaidi, S., Salahuddin, H., Patino, M., Pelaez, F., Mutis, J., Cardozo, M., Hussain, A., Lutfi, I., Ali, M., Ahmed, S., Pereira, E., Badruddin, A., Woodward, K., Wolfe, T., Langerford, C., Jankowitz, B., Costalat, V., Altschell, D., Tags: SNIS 20th annual meeting late-breaking oral abstracts Source Type: research

Thematic Analysis of Psychosocial Stressors and Adaptive Coping Strategies Among Informal Caregivers of Patients Surviving ICU Admission for Coma
ConclusionsIn response to substantial stressors, family caregivers of patients with SABI attempted to enact various psychological and behavioral coping strategies. They described avoidance and distraction as less helpful than other coping strategies but had difficulty engaging in alternative strategies because of their emotional distress. These findings can directly inform the development of additional resources to mitigate the long-term impact of acute psychological distress among this caregiver population.
Source: Neurocritical Care - July 31, 2023 Category: Neurology Source Type: research

E-078 Advancement in coil technology for treatment of brain aneurysms
ConclusionThis study concludes that is SMART coil system is safe and efficacious for the use in Endovascular treatment of intracranial aneurysms. The smart coil system is promising in the treatment of wide spectrum of intracranial aneurysms. The result of follow up angiographic data should reflect the high packing density and will be published when completed.Disclosures S. Khairandish: None. S. Pakbaz: None. M. McManus: None. G. Ammirati: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Khairandish, S., Pakbaz, S., McManus, M., Ammirati, G. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-108 Endovascular treatment of patients with acute ischemic stroke due to underlying arterial dissection: a nationwide analysis
ConclusionsDespite a similar prevalence among patients admitted for AIS, CA dissections are associated with a higher rate of endovascular intervention and poorer short-term outcomes compared to VA dissections. This study provides essential epidemiologic and outcome data for the cerebrovascular neurosurgeon.Abstract E-108 Table 1Comparison of clinical characteristics and outcomes among patients presenting with acute ischemic stroke due to carotid or vertebral artery dissections Characteristic Vertebral Artery Dissection, N = 2,562 Carotid Artery Dissection, N = 2,789 p-value1 Age (years), Mean (SD) 53 (17) 57 (17) <0.00...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Brandel, M., McCann, C., Wali, A., Wu, V., Esmail, S., Steinberg, J., Olson, S., Pannell, J., Khalessi, A., Santiago-Dieppa, D. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-126 Multicenter flow diversion in 200 patients for treatment of intracranial aneurysms
ConclusionThis report characterizes patient demographics, aneurysm characteristics, procedure complications and long-term angiographic and clinical outcomes for a large patient population across multiple medical centers treated with flow diversion. Overall, procedures resulted in a high rate of occlusion and low rate of serious complications. Continued iterative outcomes analysis is warranted particularly as flow diversion technology evolves. Despite diverse hospital settings, differences in presentation, patient characteristics and the inclusion of off-label treatments, flow diversion procedures remained safe and effectiv...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Meister, R., Lesko, A., Marginean, H., Deshmukh, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

E-189 Outcomes of tenecteplase versus alteplase after mechanical thrombectomy in a multiethnic stroke consortium registry
ConclusionIn this prospective, multi-center stroke consortium study, IV TNK in comparison to tPA prior to MT for ischemic stroke resulted in non-inferior outcomes related to angiographic reperfusion and functional status at discharge. These findings compliment the current literature and include a large Hispanic US cohort. Further analysis will include expansion of contributing centers and use of propensity scoring.Abstract E-189 Table 1 and 2Disclosures M. Gaub: None. D. Ramaswamy: None. A. Cardentey: None. S. Bandela: None. G. Gealogo: None. J. Mascitelli: None. F. Al Saiegh: None. L. Birnbaum: 2; C; Rapid AI, Imperative Care.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Gaub, M., Ramaswamy, D., Cardentey, A., Bandela, S., Gealogo, G., Mascitelli, J., Al Saiegh, F., Birnbaum, L. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P-028 Impact of the covid-19 pandemic on the intracranial aneurysm treatment and associated outcomes: a propensity score matching study
Conclusions and RelevanceThe COVID-19 pandemic has significantly impacted the healthcare system and has led to changes in the treatment of various neurological conditions, including ICAs. The pandemic resulted in a shift in the treatment of SAH and an increase in endovascular procedures over open surgical clipping. COVID-19 infection has been associated with an increased risk of ischemic stroke and worsened outcomes for stroke patients. Further research is necessary to understand the long-term effects of the pandemic on the healthcare system and patient outcomes.Disclosures A. Ghaith: None. M. Ghanem: None. E. Greco: None....
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ghaith, A., Ghanem, M., Greco, E., Rios-Zermeno, J., Bon Nieves, A., Kashyap, S., Tawk, R., Bydon, M. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research

E-020 Flow diversion for intracranial aneurysms: intracranial hemorrhage and thromboembolic complications in a multi-center cohort of 200 patients
ConclusionComplication rates in our study are comparable to previous reports, and our findings further support the general safety and efficacy of flow diversion. Despite a relatively large population, the low number of ICH and TE complications limit statistical significance. Further study of complications in more robust samples are needed. However, the descriptive understanding of these complications can help direction future investigations.Abstract E-020 Table 1ICH and TE Stratifications ICH Non-ICH p n=7 n=193 Hypertension 7 (100%) 97 (50.3%) 0.035 Currently Smoking 3 (42.9%) 28 (14.5%) 0.319 Mean Procedural Fluoroscopi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Meister, R., Lesko, A., Marginean, H., Deshmukh, V. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Neurobehavioral Impairments Predict Specific Cerebral Damage in Rat Model of Subarachnoid Hemorrhage
This study suggests that recurring behavioral testing can accurately predict damage in specific brain regions, which could be developed into a clinical battery for early detection of SAH damage in humans, potentially improving early treatment and outcomes.
Source: Translational Stroke Research - July 26, 2023 Category: Neurology Source Type: research

Regional disparity in continuously measured time-domain cerebrovascular reactivity indices: a scoping review of human literature
Objective:  Cerebral blood vessels maintaining relatively constant cerebral blood flow (CBF) over wide range of systemic arterial blood pressure (ABP) is referred to as cerebral autoregulation (CA). Impairments in CA expose the brain to pressure-passive flow states leading to hypoperfusion and hyperperfusion. Cerebrovascular reactivity (CVR) metrics refer to surrogate metrics of pressure-based CA that evaluate the relationship between slow vasogenic fluctuations in cerebral perfusion pressure/ABP and a surrogate for pulsatile CBF/cerebral blood volume. Approach: We performed a systematically conducted scoping review of a...
Source: Physiological Measurement - July 23, 2023 Category: Physiology Authors: Amanjyot Singh Sainbhi, Izabella Marquez, Alwyn Gomez, Kevin Y Stein, Fiorella Amenta, Nuray Vakitbilir, Logan Froese and Frederick A Zeiler Source Type: research

CXCR2 antagonism attenuates neuroinflammation after subarachnoid hemorrhage
Subarachnoid hemorrhage (SAH) is the deadliest form of a severe cerebrovascular disease, with substantial morbidity and mortality.1 It has been increasingly recognized that SAH induces a series of pathophysiological processes, including neuronal apoptosis,2 neuroinflammatory reactions,3 blood ‒brain barrier disruption,4 and oxidative stress5 are key factors that affect the prognosis of SAH patients. Accumulating evidence has suggested that SAH seriously destroys the extracellular environment of glial cells and immune cells, and then those cells are activated, which produce and release excessive inflammatory cytokines, th...
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2023 Category: Neurology Authors: Xiaolin Luo Source Type: research

Clopidogrel Is Associated with Reduced Likelihood of Aneurysmal Subarachnoid Hemorrhage: a Multi-Center Matched Retrospective Analysis
We present, to the best of our knowledge, the first large-scale multi-institutional analysis suggesting clopidogrel use is protective against intracranial aneurysm rupture. It is our hope that these data will guide future investigation, revealing the pathophysiologic underpinning of this association.
Source: Translational Stroke Research - July 20, 2023 Category: Neurology Source Type: research

Surpass embolization of intracranial aneurysms: Perspective from a 2-year longitudinal follow-up study across high volume comprehensive stroke centers
CONCLUSION: Large-scale future registry should focus on national data regarding SS safety, technical challenges, and procedural complications. We present one of the longest follow-ups for SS in literature.PMID:37464776 | DOI:10.1177/15910199231188760
Source: Interventional Neuroradiology - July 19, 2023 Category: Radiology Authors: Gaurav Gupta Sanjeev Sreenivasan Ian Kane Lauren Salguiero Ali Saifuddin Srihari Sundararajan Priyank Khandelwal Emad Nourallah-Zadeh Hai Sun Ashish Sonig Amit Singla Anil Nanda Sudipta Roychowdhury Source Type: research