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Condition: Hemorrhagic Stroke
Therapy: Statin Therapy

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Total 361 results found since Jan 2013.

Effects of Statin Intensity and Adherence on the Long-Term Prognosis After Acute Ischemic Stroke Clinical Sciences
Conclusions—After acute ischemic stroke, high-intensity statin therapy with good adherence was significantly associated with a lower risk of adverse events.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Jinkwon Kim, Hye Sun Lee, Chung Mo Nam, Ji Hoe Heo Tags: Secondary Prevention, Compliance/Adherence, Ischemic Stroke Original Contributions Source Type: research

Secondary prevention treatment after acute stroke in older South Asian, Chinese and other Canadians: a retrospective data analysis.
Abstract BACKGROUND: Little is known about whether there are differences in medication use between older patients of Chinese descent, those of South Asian descent and other Canadian patients after acute ischemic or primary intracerebral hemorrhagic stroke. The aim of this population-based study was to evaluate potential ethnic differences in secondary prevention pharmacotherapy after acute stroke. METHODS: Using health administrative data, we conducted a retrospective analysis of all patients aged 66 years or more admitted to hospital with acute stroke in Ontario (1997-2011) and British Columbia (1997-2009). ...
Source: cmaj - September 11, 2017 Category: General Medicine Authors: Khan NA, McAlister FA, Pilote L, Palepu A, Quan H, Hill MD, Fang J, Kapral MK Tags: CMAJ Open Source Type: research

Use of Statins and Outcomes in Intracerebral Hemorrhage Patients Clinical Sciences
Conclusions—Although statin use, especially continued/new use, was associated with improved intracerebral hemorrhage outcomes, this effect may merely reflect the physician’s view of a patient’s prognosis rather than a predictor of survival.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Fazeel M. Siddiqui, Carl D. Langefeld, Charles J. Moomaw, Mary E. Comeau, Padmini Sekar, Jonathan Rosand, Chelsea S. Kidwell, Sharyl Martini, Jennifer L. Osborne, Sonja Stutzman, Christiana Hall, Daniel Woo Tags: Intracranial Hemorrhage Original Contributions Source Type: research

Combined renin-angiotensin-aldosterone system blockade and statin therapy effectively reduces the risk of cerebrovascular accident in autosomal dominant polycystic kidney disease: a nationwide population-based cohort study.
In conclusion, ADPKD was associated with an increased risk of CVA occurrence. Combined RAAS blockade and statin therapy effectively reduces the risk of CVA in ADPKD. PMID: 28711910 [PubMed - as supplied by publisher]
Source: Oncotarget - July 18, 2017 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Statin Therapy and Risk of Intracranial Hemorrhage in Patients with Ischemic Stroke
Source: Drug Safety - July 10, 2017 Category: Drugs & Pharmacology Source Type: research

Lipophilic Statins and the Risk of Intracranial Hemorrhage Following Ischemic Stroke: A Population-Based Study
ConclusionAmong patients treated with a statin following ischemic stroke, the risk of intracranial hemorrhage is not influenced by statin lipophilicity.
Source: Drug Safety - June 15, 2017 Category: Drugs & Pharmacology Source Type: research

Transient ischemic attack and ischemic stroke patients with or without prior stroke
ConclusionsBoth in TIA and IS, vascular risk factors were more common in patients with a history of stroke compared with those without. In contrast to other secondary preventive medications, OAC treatment in the presence of AF was underutilized in patients with a history of stroke.
Source: Acta Neurologica Scandinavica - June 1, 2017 Category: Neurology Authors: F. Buchwald, B. Norrving, J. Petersson Tags: ORIGINAL ARTICLE Source Type: research

Stroke in patients with chronic kidney disease & #8230;: How do we approach and manage it ?
This article is a review of stroke in patients with CKD and approach to managing it.
Source: Indian Journal of Nephrology - May 3, 2017 Category: Urology & Nephrology Authors: S Nayak-Rao MP Shenoy Source Type: research

Moyamoya Vasculopathy in a Patient with Scleroderma: A Case Report and Review of the Literature (P3.273)
Conclusions:MMS in the context of scleroderma is a very rare entity. The angiographic findings are result of a systemic process at the cellular level, independent of atheromatous changes. They may represent progressive vasculopathy different from the classically described Suzuki stages for moyamoya disease.Disclosure: Dr. Ahmad has nothing to disclose. Dr. Tahir has nothing to disclose. Dr. Mitsias has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ahmad, A., Tahir, R., Mitsias, P. Tags: Cerebrovascular Disease Case Reports II Source Type: research

The effect of statins on National Institutes of Health Stroke Scale (NiHSS) in Ischemic stroke.
Conclusion. According to the findings of this research, taking statins before the onset of stroke and immediately after it showed no significant difference in the level of following dysfunction, measured with NIHSS, and further studies are necessary. PMID: 28316706 [PubMed]
Source: Journal of Medicine and Life - March 23, 2017 Category: Journals (General) Tags: J Med Life Source Type: research

Reduction in High-Sensitivity C-Reactive Protein Levels in Patients with Ischemic Stroke by Statin Treatment: Hs-CRP Sub-Study in J-STARS.
CONCLUSION: In non-cardiogenic ischemic stroke, pravastatin treatment may reduce vascular inflammation as assessed by Hs-CRP, and higher Hs-CRP levels appeared to increase the risk of recurrent stroke and vascular events. PMID: 28302952 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - March 19, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Safety, immediate and mid-term results of the newer generation of hydrogel coils in the treatment of ruptured aneurysms: a multicenter study
Conclusions Our data show that the use of the newer-generation hydrogel coils in the treatment of ruptured aneurysms is feasible, safe and effective with high immediate and mid-term occlusion rates and low morbidity.
Source: Journal of NeuroInterventional Surgery - March 15, 2017 Category: Neurosurgery Authors: Dabus, G., Hacein-Bey, L., Varjavand, B., Tomalty, R. D., Han, P. P., Yerokhin, V., Linfante, I., Mocco, J., Oxley, T., Spiotta, A., Chaudry, M. I., Turner, R. D., Turk, A. S. Tags: Hemorrhagic stroke Source Type: research

The efficacy and safety of high-dose statins in acute phase of ischemic stroke and transient ischemic attack: a systematic review
AbstractInconsistent findings in the studies have been observed concerning the higher dose of statins use in the acute phase of ischemic stroke and transient ischemic attack (TIA). Therefore, we performed a systematic review to assess this issue. A computerized literature search in PubMed, Cochrane Library databases, and EMBASE for randomized controlled trials (RCTs) was conducted. The efficacy outcome indicators were National Institutes of Health Stroke Scale (NIHSS) score, infarct volume, and recurrence of stroke; the safety outcome indicators were intracranial hemorrhage events, cardiovascular and cerebrovascular events...
Source: Internal and Emergency Medicine - March 15, 2017 Category: Emergency Medicine Source Type: research

Adverse Effects of Statins
To the Editor In his Viewpoint, Dr Thompson wrote, “Although statins reduce total stroke, they increase the risk of hemorrhagic stroke consistent with the observation that low cholesterol levels are associated with an increase in hemorrhagic stroke.” The statement could be misleading and requires clarification.
Source: JAMA - March 14, 2017 Category: Journals (General) Source Type: research