Peculiar acral melanosis after cyclophosphamide therapy in a case of primary membranous nephropathy: A rare presentation
Shivangi Gharia, Karthikeyan Balasubramanian, Sanjeev V Nair, Kavitha Mohanasundaram, Soundararajan PeriasamyIndian Journal of Nephrology 2020 30(5):357-358 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Shivangi Gharia Karthikeyan Balasubramanian Sanjeev V Nair Kavitha Mohanasundaram Soundararajan Periasamy Source Type: research

Perplexing etiology of acute retinal necrosis in a renal transplant recipient
Sudeep Prakash, Vivek Sood, Arun Joshi, Pavitra M Dogra, Arun Dua, Satish MendoncaIndian Journal of Nephrology 2020 30(5):355-356 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Sudeep Prakash Vivek Sood Arun Joshi Pavitra M Dogra Arun Dua Satish Mendonca Source Type: research

AA amyloidosis presenting as crescentic glomerulonephritis
Praveen K Etta, Thatipamula Madhavi, Vurum Dhanalaxmi, Swarnalata GowrishankarIndian Journal of Nephrology 2020 30(5):352-354 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Praveen K Etta Thatipamula Madhavi Vurum Dhanalaxmi Swarnalata Gowrishankar Source Type: research

Right Renal Biopsy Through Petit & #39;s triangle
Subrahmanian SathiavageesanIndian Journal of Nephrology 2020 30(5):350-351 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Subrahmanian Sathiavageesan Source Type: research

Non obstructive hydrocolpos due to vesicovaginal reflux in an adolescent female
Chinky Chatur, Ankit Balani, R Prabhakar Rao, S Altaf Ali, Anand AbkariIndian Journal of Nephrology 2020 30(5):348-349 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Chinky Chatur Ankit Balani R Prabhakar Rao S Altaf Ali Anand Abkari Source Type: research

Bilateral perinephric collections in nephrotic syndrome
M Naveen Kumar, PS Priyamvada, RG Ganga, Bokka Sri Harsha, Sreejith ParameswaranIndian Journal of Nephrology 2020 30(5):346-347 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: M Naveen Kumar PS Priyamvada RG Ganga Bokka Sri Harsha Sreejith Parameswaran Source Type: research

Atypical HUS associated With CFH/CFHR-1 hybrid gene
We describe a case of a 33-year-old woman who presented as rapidly progressing renal failure requiring dialysis and had anemia, microhematuria, low C3, normal C4 levels, and normal platelet count. Renal biopsy revealed arteriolar thrombotic microangiopathy and acute tubular injury. Patient was treated with plasma exchange and hemodialysis as required. This resulted in partial recovery at 1 month. Genetic workup by multiplex ligation-dependent probe amplification revealed a 1.5 times higher signal intensity on downstream region of CFH gene and 50% reduced intensity of exon 6 of CFHR1 gene, suggesting a gene conversion e...
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Sharon Negi Vipul Chakurkar Meenal Agarwal Valentine Lobo Source Type: research

Endovascular intervention for central venous stenosis in hemodialysis patients: A single-center experience
Shobhana Nayak-Rao, Bhanushree Ramanna, K Subramanyam, M Pradeep Shenoy, Janardhan KamathIndian Journal of Nephrology 2020 30(5):337-341 Central venous stenosis (CVS) refers to a significant stenosis of a large intrathoracic vein, such as the subclavian, brachiocephalic, or the superior vena cava (hemodialysis, HD). Percutaneous transluminal angioplasty (PTA) with or without stent placement has been the recommended as the preferred approach to CVS. A total of 10 consecutive HD patients with documented CVS over a 2-year time period from April 2017-April 2019 underwent percutaneous angioplasty and stent insertions under sed...
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Shobhana Nayak-Rao Bhanushree Ramanna K Subramanyam M Pradeep Shenoy Janardhan Kamath Source Type: research

Naproxen induced acute interstitial nephritis with renal cortical necrosis
We present a case of Naproxen induced acute interstitial nephritis with acute cortical necrosis. To the best of our knowledge this is the first documented case of Naproxen induced renal cortical necrosis. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Christine M Jane V Narayanan Unni K Vinod Kumar Nanda Kachare Bipi Prasannan Jojo K Pullockara Source Type: research

Mesenteric panniculitis and rhabdomyolysis complicated by invasive fungal co-infection in a case of systemic lupus erythematosus: An autopsy report
Kirti Gupta, Gargi Kapatia, Manish Rathi, Suvradeep Mitra, Manphool Singhal, Navneet SharmaIndian Journal of Nephrology 2020 30(5):329-333 Invasive fungal infections are a significant cause of morbidity and mortality in patients systemic lupus erythematosus. The case illustrates the autopsy findings in a patient with systemic lupus erythematosus complicated by multiple fungal infections. Rare, uncommon manifestations of SLE such as mesenteric panniculitis and rhabdomyolysis were also present. High index of suspicion with timely intervention with aggressive antifungal was life-saving. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Kirti Gupta Gargi Kapatia Manish Rathi Suvradeep Mitra Manphool Singhal Navneet Sharma Source Type: research

Bilateral acute renal infarction secondary to methylene tetrahydrofolate reductase A1298C and PAI-1 mutation
We present this rare case of hyperhomocysteinemia due to a mutation in methylene-tetrahydrofolate-reductase (MTFHR) combined with plasminogen activator inhibitor deficiency, causing bilateral renal artery thrombosis. This case highlights the importance of genetic screening in individuals with a family history of thrombotic diseases. There seems to be a role of intervention, even in the setting of renal infarction. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Anil K Bhalla Vinant Bhargava Priti Meena Ashish Bhoiyar Ajay Yadav Devinder S Rana Source Type: research

Post renal transplant collapsing glomerulopathy is associated with poor outcomes
Conclusions: CG presents with moderate to severe proteinuria and may lead to rapid graft dysfunction and subsequent graft failure in most of the patients. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: B Karthikeyan M Edwin Fernando ND Srinivasaprasad S Sujit K Thirumal Valavan Anila A Kurien Source Type: research

Validation of kidney disease quality of life short form 36 (KDQOL-SF & #8482;) in malayalam among patients undergoing haemodialysis in South Kerala
Conclusion: The Malayalam version of KDQOL-SF™ is reliable and valid which can be used for measuring the health-related quality of life of Malayalam speaking CKD patients. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: L Manju Jigy Joseph Nazeema Beevi Source Type: research

The role of far infrared therapy in the unassisted maturation of arterio-venous fistula in patients with chronic kidney disease
Conclusion: In patients with CKD, FIR therapy was effective in increasing the AVF blood flow rate at the end of 3 months, though the difference in primary failure rate was statistically insignificant. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: S Murugesh Anand M Edwin Fernando B Suhasini K Valarmathi K Elancheralathan ND Srinivasaprasad S Sujit K Thirumalvalavan C Arun Prabhakaran K Jeyashree Source Type: research

Clinicopathological pattern of non-lupus full house nephropathy
Conclusions: Full-house nephropathy (FHN), not otherwise suggestive of lupus nephritis, can also be found in a number of other conditions. Non-lupus full house nephropathy is an umbrella term for such cases which do not satisfy the standard criteria of SLE. This will prevent misclassifying these patients into SLE and further prevent them from unnecessary immunosuppression protocols. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Asif S Wani Zafirah Zahir Amit Gupta Vinita Agrawal Source Type: research

Non-diabetic renal diseases in patients with diabetes mellitus clinicopathological correlation
Conclusion: Accurate diagnosis of underlying NDRD by kidney biopsy facilitates initiation of specific therapy, which may lead to clinical improvement in significant number of patients. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Puneet Arora Arpita Roychaudhury Rajendra Pandey Source Type: research

Prof. K. S. Siddaraj 1948-2020
Sankaran SundarIndian Journal of Nephrology 2020 30(5):0-0 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - October 12, 2020 Category: Urology & Nephrology Authors: Sankaran Sundar Source Type: research

Study of FGF 23 levels in patients with acute kidney injury and its outcome
Krishan Lal Gupta, Tirthankar Mohanty, Vivek Sood, Raja RamachandranIndian Journal of Nephrology 2020 30(4):293-294 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Krishan Lal Gupta Tirthankar Mohanty Vivek Sood Raja Ramachandran Source Type: research

Crystalline nephropathy due to APRT deficiency: A preventable cause of renal and renal allograft failure
We report two cases of APRT deficiency from our center. DNA sequencing of APRT gene performed in one of the cases revealed a pathogenic variant in Exon1 of APRT gene (c.3G>C; p.Met1). This variant affects the translation initiation codon and results in a start loss. The variant has previously been reported in two cases with APRT deficiency. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Prashant Rajput Zaheer A Virani Bharat V Shah Source Type: research

Novel variation in CFB adult onset atypical hemolytic uremic syndrome: A case report and review
We report a case of 47-year-old male with atypical hemolytic uremic syndrome (aHUS). He had low C3 levels and whole exome sequencing revealed heterozygous missense novel variation in exon 8 of the gene encoding complement factor B (CFB), leading to substitution of leucine for proline at codon 369 (c.1106C>T; p.Pro369Leu). Following plasma exchanges and hemodialysis, the patient achieved hematological remission and became dialysis independent. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Malsawmkima Chhakchhuak Jony Agarwal Source Type: research

Novel homozygous FAN1 mutation in a familial case of karyomegalic interstitial nephritis
We present a case report of a 47-year-old multiparous South-Indian woman presenting with bilateral pitting pedal oedema and mild hypertension. At the time of presentation, her serum creatinine was 1.52 mg/dL and urine analysis showed mild proteinuria. Kidney biopsy showed features of tubular injury with bizarre enlarged nuclei and focal mild chronic tubulointerstitial nephritis. Immunohistochemistry was negative for cytomegalovirus (CMV) Ag and SV40 Ag. Real-time polymerase chain reaction (PCR) done for CMV and BK virus genomes was negative. Relevant family history was that her older brother was also diagnosed with kidney ...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Priyanka J Koshy Digumarthi V. S. Sudhakar Sneha H Anupama Milly Mathew Rajeevalochana Parthasarthy Kumarasamy Thangaraj Muhammad Magdi Yaqoob Georgi Abraham Source Type: research

Nephrology postgraduate training in peritoneal dialysis: An online survey
Discussion: The conclusion may be drawn from our study that the postgraduate training in PD in our country is gratifying. Our hypothesis that a lacuna in postgraduate training in PD may be one of the reasons for the underutilization of PD seems ungrounded. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Sangeetha Lakshmi B Varalakshmi N Sai Sameera A Sunnesh R Ram V Siva Kumar Source Type: research

Transforming growth factor-beta 1 and endoglin levels in congenital solitary functioning kidney
Conclusions: Endoglin and TGF-β1 may play an important role in the pathophysiology of microalbuminuria in cSFK. Endoglin may have a role in the development of hypertension in children with cSFK. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Nuran Cetin Nadide Melike Sav Zeynep Kusku K & #305;raz Aylin Gencler Source Type: research

Gerontolizing nephrology: Spectrum of histopathological findings of kidney biopsy in the elderly
Conclusion: Renal biopsy is safe in the elderly and provides a wealth of information with regards to the diagnosis and prognosis of renal disorder. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Pankaj Beniwal Shailendra K Singh Vinay Malhotra Dhananjai Agarwal Manish Sharma Parvati Joshi Shikha Khandelwal Nisha Gaur Sanjeev Sharma Source Type: research

Options of renal replacement therapy in CKDu
Santosh Varughese, Sanjay K Agarwal, T Ravi Raju, Tripti KhannaIndian Journal of Nephrology 2020 30(4):261-263 Patients with advanced Chronic Kidney Disease of Unknown origin (CKDu) need to plan for renal replacement therapy. The patients usually affected are probably best served with living-related renal transplantation. Potential donors from the same area are possibly at risk for developing CKDu and need close monitoring post kidney donation. Peritoneal dialysis (PD) is probably a better option as hemodialysis (HD) centers are located in urban areas only and patients have the convenience of receiving therapy at home. Th...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Santosh Varughese Sanjay K Agarwal T Ravi Raju Tripti Khanna Source Type: research

Dietary management in slowing down the progression of CKDu
The objective is to prevent malnutrition, and uremic symptoms. Early diagnosis and prompt intervention may delay the progression of CKDu in the early stages. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Priya Haridas Anupama Narayan Prasad Victorine B Nzana JP Tiwari Milly Mathew Georgi Abraham Source Type: research

Pathology of uddanam endemic nephropathy
Swarnalata Gowrishankar, Priyanka Koshy, Milly Mathew, N Gopalakrishnan, V Siva Kumar, Georgi AbrahamIndian Journal of Nephrology 2020 30(4):253-255 In the last decade, pockets of endemic nephropathy have been recognized worldwide, in regions of Central America, Sri Lanka, and India. In India, the nephropathy has been recognized in the Uddanam area of north Andhra Pradesh and has been termed the Uddanam endemic nephropathy (UEN). The disease is distinctive in that besides the geographic distribution, it affects rural populations engaged in farm labor and agriculture, often silent in the initial phase with most patients pr...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Swarnalata Gowrishankar Priyanka Koshy Milly Mathew N Gopalakrishnan V Siva Kumar Georgi Abraham Source Type: research

A review of chronic kidney disease of unknown etiology in Sri Lanka, 2001 & #8211;2015
Prabhdeep Kaur, Nalika Gunawardena, Jacob KumaresanIndian Journal of Nephrology 2020 30(4):245-252 An increase in the prevalence of chronic kidney disease of unknown etiology (CKDu) was observed in several countries of the world since the early 2000s. We reviewed the literature to summarize the existing knowledge regarding epidemiology, clinical features, and risk factors for CKDu in Sri Lanka. We reviewed published literature from PubMed and unpublished literature from literature repository of CKDu published by the World Health Organization. We identified 36 articles based on various inclusion/exclusion criteria and revi...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Prabhdeep Kaur Nalika Gunawardena Jacob Kumaresan Source Type: research

Distribution and determinants of chronic kidney disease of unknown etiology: A brief overview
P Stalin, Anil J Purty, Georgi AbrahamIndian Journal of Nephrology 2020 30(4):241-244 Globally, 33187000 DALYs and 956000 deaths are attributed to chronic kidney disease (CKD) every year. Diabetes and hypertension are the two most common causes of CKD. Another category of CKD without any known common causes, chronic kidney disease of unknown etiology (CKDu) is also increasingly reported from different regions of the world such as Central America, Sri Lanka, and India. They are predominately observed in agricultural communities where crops such as sugarcane and coconut are commonly cultivated. Young adults and males are at...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: P Stalin Anil J Purty Georgi Abraham Source Type: research

Chronic kidney disease of unknown etiology: Case definition for India & #8211; A perspective
This article presents the diagnostic criteria for CKDu proposed in a consensus meeting at Chennai, India, in May 2017. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: YJ Anupama Suresh Sankarasubbaiyan Gangadhar Taduri Source Type: research

Preface
Georgi Abraham, Sanjay Kumar AgarwalIndian Journal of Nephrology 2020 30(4):235-235 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Georgi Abraham Sanjay Kumar Agarwal Source Type: research

Foreward
Balram BhargavaIndian Journal of Nephrology 2020 30(4):234-234 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Balram Bhargava Source Type: research

KDIGO 2017 clinical practice guideline update for the diagnosis, evaluation, prevention and prevention of chronic kidney disease-mineral and bone disorder (CKDMBD): Indian commentary
Anna T Valson, Manisha Sahay, Narayan Prasad, Sanjay Kumar Agarwal, Santosh Varughese, Sishir GangIndian Journal of Nephrology 2020 30(4):221-233 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Anna T Valson Manisha Sahay Narayan Prasad Sanjay Kumar Agarwal Santosh Varughese Sishir Gang Source Type: research

NOTTO transplant specific guidelines with reference to COVID-19
Vivek Kute, Sandeep Guleria, Jai Prakash, Sunil Shroff, Narayan Prasad, Sanjay K Agarwal, Santosh Varughese, Subhash Gupta, AG K Gokhale, Manisha Sahay, Ashish Sharma, Prem Varma, Anil Bhalla, Harsh Vardhan, Manish Balwani, Shruti Dave, Dhamendra Bhadauria, Manish Rathi, Dhananjay Agarwal, Pankaj Shah, Vasanthi Ramesh, Rajiv GargIndian Journal of Nephrology 2020 30(4):215-220 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Vivek Kute Sandeep Guleria Jai Prakash Sunil Shroff Narayan Prasad Sanjay K Agarwal Santosh Varughese Subhash Gupta AG K Gokhale Manisha Sahay Ashish Sharma Prem Varma Anil Bhalla Harsh Vardhan Manish Balwani Shruti Dave Dhamendra Bhadauria Manish Rathi D Source Type: research

Study of FGF 23 levels in patients with acute kidney injury and its outcome
Krishan Lal Gupta, Tirthankar Mohanty, Vivek Sood, Raja RamachandranIndian Journal of Nephrology 2020 30(4):293-294 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Krishan Lal Gupta Tirthankar Mohanty Vivek Sood Raja Ramachandran Source Type: research

Crystalline nephropathy due to APRT deficiency: A preventable cause of renal and renal allograft failure
We report two cases of APRT deficiency from our center. DNA sequencing of APRT gene performed in one of the cases revealed a pathogenic variant in Exon1 of APRT gene (c.3G>C; p.Met1). This variant affects the translation initiation codon and results in a start loss. The variant has previously been reported in two cases with APRT deficiency. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Prashant Rajput Zaheer A Virani Bharat V Shah Source Type: research

Novel variation in CFB adult onset atypical hemolytic uremic syndrome: A case report and review
We report a case of 47-year-old male with atypical hemolytic uremic syndrome (aHUS). He had low C3 levels and whole exome sequencing revealed heterozygous missense novel variation in exon 8 of the gene encoding complement factor B (CFB), leading to substitution of leucine for proline at codon 369 (c.1106C>T; p.Pro369Leu). Following plasma exchanges and hemodialysis, the patient achieved hematological remission and became dialysis independent. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Malsawmkima Chhakchhuak Jony Agarwal Source Type: research

Novel homozygous FAN1 mutation in a familial case of karyomegalic interstitial nephritis
We present a case report of a 47-year-old multiparous South-Indian woman presenting with bilateral pitting pedal oedema and mild hypertension. At the time of presentation, her serum creatinine was 1.52 mg/dL and urine analysis showed mild proteinuria. Kidney biopsy showed features of tubular injury with bizarre enlarged nuclei and focal mild chronic tubulointerstitial nephritis. Immunohistochemistry was negative for cytomegalovirus (CMV) Ag and SV40 Ag. Real-time polymerase chain reaction (PCR) done for CMV and BK virus genomes was negative. Relevant family history was that her older brother was also diagnosed with kidney ...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Priyanka J Koshy Digumarthi V. S. Sudhakar Sneha H Anupama Milly Mathew Rajeevalochana Parthasarthy Kumarasamy Thangaraj Muhammad Magdi Yaqoob Georgi Abraham Source Type: research

Nephrology postgraduate training in peritoneal dialysis: An online survey
Discussion: The conclusion may be drawn from our study that the postgraduate training in PD in our country is gratifying. Our hypothesis that a lacuna in postgraduate training in PD may be one of the reasons for the underutilization of PD seems ungrounded. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Sangeetha Lakshmi B Varalakshmi N Sai Sameera A Sunnesh R Ram V Siva Kumar Source Type: research

Transforming growth factor-beta 1 and endoglin levels in congenital solitary functioning kidney
Conclusions: Endoglin and TGF-β1 may play an important role in the pathophysiology of microalbuminuria in cSFK. Endoglin may have a role in the development of hypertension in children with cSFK. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Nuran Cetin Nadide Melike Sav Zeynep Kusku K & #305;raz Aylin Gencler Source Type: research

Gerontolizing nephrology: Spectrum of histopathological findings of kidney biopsy in the elderly
Conclusion: Renal biopsy is safe in the elderly and provides a wealth of information with regards to the diagnosis and prognosis of renal disorder. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Pankaj Beniwal Shailendra K Singh Vinay Malhotra Dhananjai Agarwal Manish Sharma Parvati Joshi Shikha Khandelwal Nisha Gaur Sanjeev Sharma Source Type: research

Options of renal replacement therapy in CKDu
Santosh Varughese, Sanjay K Agarwal, T Ravi Raju, Tripti KhannaIndian Journal of Nephrology 2020 30(4):261-263 Patients with advanced Chronic Kidney Disease of Unknown origin (CKDu) need to plan for renal replacement therapy. The patients usually affected are probably best served with living-related renal transplantation. Potential donors from the same area are possibly at risk for developing CKDu and need close monitoring post kidney donation. Peritoneal dialysis (PD) is probably a better option as hemodialysis (HD) centers are located in urban areas only and patients have the convenience of receiving therapy at home. Th...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Santosh Varughese Sanjay K Agarwal T Ravi Raju Tripti Khanna Source Type: research

Dietary management in slowing down the progression of CKDu
The objective is to prevent malnutrition, and uremic symptoms. Early diagnosis and prompt intervention may delay the progression of CKDu in the early stages. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Priya Haridas Anupama Narayan Prasad Victorine B Nzana JP Tiwari Milly Mathew Georgi Abraham Source Type: research

Pathology of uddanam endemic nephropathy
Swarnalata Gowrishankar, Priyanka Koshy, Milly Mathew, N Gopalakrishnan, V Siva Kumar, Georgi AbrahamIndian Journal of Nephrology 2020 30(4):253-255 In the last decade, pockets of endemic nephropathy have been recognized worldwide, in regions of Central America, Sri Lanka, and India. In India, the nephropathy has been recognized in the Uddanam area of north Andhra Pradesh and has been termed the Uddanam endemic nephropathy (UEN). The disease is distinctive in that besides the geographic distribution, it affects rural populations engaged in farm labor and agriculture, often silent in the initial phase with most patients pr...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Swarnalata Gowrishankar Priyanka Koshy Milly Mathew N Gopalakrishnan V Siva Kumar Georgi Abraham Source Type: research

A review of chronic kidney disease of unknown etiology in Sri Lanka, 2001 & #8211;2015
Prabhdeep Kaur, Nalika Gunawardena, Jacob KumaresanIndian Journal of Nephrology 2020 30(4):245-252 An increase in the prevalence of chronic kidney disease of unknown etiology (CKDu) was observed in several countries of the world since the early 2000s. We reviewed the literature to summarize the existing knowledge regarding epidemiology, clinical features, and risk factors for CKDu in Sri Lanka. We reviewed published literature from PubMed and unpublished literature from literature repository of CKDu published by the World Health Organization. We identified 36 articles based on various inclusion/exclusion criteria and revi...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Prabhdeep Kaur Nalika Gunawardena Jacob Kumaresan Source Type: research

Distribution and determinants of chronic kidney disease of unknown etiology: A brief overview
P Stalin, Anil J Purty, Georgi AbrahamIndian Journal of Nephrology 2020 30(4):241-244 Globally, 33187000 DALYs and 956000 deaths are attributed to chronic kidney disease (CKD) every year. Diabetes and hypertension are the two most common causes of CKD. Another category of CKD without any known common causes, chronic kidney disease of unknown etiology (CKDu) is also increasingly reported from different regions of the world such as Central America, Sri Lanka, and India. They are predominately observed in agricultural communities where crops such as sugarcane and coconut are commonly cultivated. Young adults and males are at...
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: P Stalin Anil J Purty Georgi Abraham Source Type: research

Chronic kidney disease of unknown etiology: Case definition for India & #8211; A perspective
This article presents the diagnostic criteria for CKDu proposed in a consensus meeting at Chennai, India, in May 2017. (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: YJ Anupama Suresh Sankarasubbaiyan Gangadhar Taduri Source Type: research

Preface
Georgi Abraham, Sanjay Kumar AgarwalIndian Journal of Nephrology 2020 30(4):235-235 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Georgi Abraham Sanjay Kumar Agarwal Source Type: research

Foreward
Balram BhargavaIndian Journal of Nephrology 2020 30(4):234-234 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Balram Bhargava Source Type: research

KDIGO 2017 clinical practice guideline update for the diagnosis, evaluation, prevention and prevention of chronic kidney disease-mineral and bone disorder (CKDMBD): Indian commentary
Anna T Valson, Manisha Sahay, Narayan Prasad, Sanjay Kumar Agarwal, Santosh Varughese, Sishir GangIndian Journal of Nephrology 2020 30(4):221-233 (Source: Indian Journal of Nephrology)
Source: Indian Journal of Nephrology - August 19, 2020 Category: Urology & Nephrology Authors: Anna T Valson Manisha Sahay Narayan Prasad Sanjay Kumar Agarwal Santosh Varughese Sishir Gang Source Type: research