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Condition: Hemorrhagic Stroke
Procedure: MRI Scan

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Total 775 results found since Jan 2013.

Prevention of rt-PA induced blood brain barrier component degradation by the poly(ADP-ribose)polymerase inhibitor PJ34 after ischemic stroke in mice.
Abstract Recombinant tissue plasminogen activator (rt-PA) is the only pharmacological treatment approved for thrombolysis in patients suffering from ischemic stroke, but its administration aggravates the risk of hemorrhagic transformations. Experimental data demonstrated that rt-PA increases the activity of poly(ADP-ribose)polymerase (PARP). The aim of the present study was to investigate whether PJ34, a potent (PARP) inhibitor, protects the blood brain barrier components from rt-PA toxicity. In our mouse model of cerebral ischemia, administration of rt-PA (10 mg/kg, i.v.) 6 hours after ischemia aggravated the pos...
Source: Experimental Neurology - July 19, 2013 Category: Neurology Authors: Teng F, Beray-Berthat V, Coqueran B, Lesbats C, Kuntz M, Palmier B, Garraud M, Bedfert C, Slane N, Bérézowski V, Szeremeta F, Hachani J, Scherman D, Plotkine M, Doan BT, Marchand-Leroux C, Margaill I Tags: Exp Neurol Source Type: research

Clinical significance of pathological eye movements in diagnosing posterior fossa stroke.
Conclusion: Close observation of pathological eye movements such as disconjugate eye movements, multi-directional gaze nystagmus, and persistent unilateral gaze nystagmus may facilitate the effort of clinicians to arrange magnetic resonance imaging (MRI) study, because physical examinations may overlook the posterior fossa lesions. Objective: This paper reviews our experience of patients with posterior fossa stroke via observation of pathological eye movements over the past 10 years. Methods: Seventy patients with posterior fossa stroke manifested as acute vertiginous attack were admitted. All patients underwent examinatio...
Source: Acta Oto-Laryngologica - August 18, 2013 Category: ENT & OMF Authors: Su CH, Young YH Tags: Acta Otolaryngol Source Type: research

Detection of ischemic penumbra using combined perfusion and T2* oxygen challenge imaging
ConclusionsIn conclusion, T2* oxygen challenge combined with perfusion imaging has advantages over alternative magnetic resonance imaging techniques for penumbra detection by providing serial assessment of available penumbra based on tissue viability.
Source: International Journal of Stroke - July 15, 2014 Category: Neurology Authors: Craig A. Robertson, Christopher McCabe, M. Rosario Lopez‐Gonzalez, Graeme A. Deuchar, Krishna Dani, William M. Holmes, Keith W. Muir, Celestine Santosh, I. Mhairi Macrae Tags: Research Source Type: research

Detection of Vessel Wall Lesions in Spontaneous Symptomatic Vertebrobasilar Artery Dissection Using T1-weighted 3-dimensional Imaging
Conclusions: The T1W 3D-VWI can directly visualize vessel wall iVBD lesions during the acute period of stroke compared with multisequence MRI.
Source: Journal of Stroke and Cerebrovascular Diseases - August 29, 2014 Category: Neurology Authors: Tatsunori Natori, Makoto Sasaki, Mitsuharu Miyoshi, Hideki Ohba, Mao Yamaguchi Oura, Shinsuke Narumi, Taisuke Harada, Hiroyuki Kabasawa, Yasuo Terayama Tags: Original Articles Source Type: research

Emergency Management of Ischemic Stroke in Children
Opinion statement Children who present with acute neurological symptoms suggestive of a stroke need immediate clinical assessment and urgent neuroimaging to confirm diagnosis. Magnetic resonance imaging (MRI) is the investigation of first choice due to limited sensitivity of computed tomography (CT) for detection of ischaemia. Acute monitoring should include monitoring of blood pressure and body temperature, and neurological observations. Surveillance in a paediatric high dependency or intensive care unit and neurosurgical consultation are mandatory in children with large infarcts at risk of developing malignant ...
Source: Current Treatment Options in Neurology - April 9, 2015 Category: Neurology Source Type: research

Magnetic Resonance Imaging of Acute Stroke
Neuroimaging plays a critical role in the management of patients with acute stroke syndrome, with diagnostic, therapeutic, and prognostic implications. A multiparametric magnetic resonance (MR) imaging protocol in the emergency setting can address both primary goals of neuroimaging (ie, detection of infarction and exclusion of hemorrhage) and secondary goals of neuroimaging (ie, identifying the site of arterial occlusion, tissue characterization for defining infarct core and penumbra, and determining stroke cause/mechanism). MR imaging provides accurate diagnosis of acute ischemic stroke (AIS) and can differentiate AIS fro...
Source: Magnetic Resonance Imaging Clinics of North America - February 17, 2016 Category: Radiology Authors: Kambiz Nael, Wayne Kubal Source Type: research

Chapter 66 Endovascular treatment of acute ischemic stroke
Publication date: 2016 Source:Handbook of Clinical Neurology, Volume 136 Author(s): Thabele Leslie-Mazwi, James Rabinov, Joshua A. Hirsch Endovascular thrombectomy is an effective treatment for major acute ischemic stroke syndromes caused by major anterior circulation artery occlusions (commonly referred to as large vessel occlusion) and is superior to intravenous thrombolysis and medical management. Treatment should occur as quickly as is reasonably possible. All patients with moderate to severe symptoms (National Institutes of Health stroke scale >8) and a treatable occlusion should be considered. The use of ...
Source: Handbook of Clinical Neurology - July 16, 2016 Category: Neurology Source Type: research

Visual hallucinations in patients with acute stroke: a prospective exploratory study
ConclusionsVisual hallucinations are relatively frequent in patients with acute stroke and they are self‐limited. Patients with occipital lesions and sleep disturbances are more likely to suffer them.
Source: European Journal of Neurology - March 23, 2017 Category: Neurology Authors: E. Morenas ‐Rodríguez, P. Camps‐Renom, A. Pérez‐Cordón, A. Horta‐Barba, M. Simón‐Talero, E. Cortés‐Vicente, D. Guisado‐Alonso, E. Vilaplana, C. García‐Sánchez, A. Gironell, C. Roig, R. Delgado‐Mederos, J. Martí‐Fàbregas Tags: Original Article Source Type: research

Thrombolysis After Protamine Reversal of Heparin for Acute Ischemic Stroke After Cardiac Catheterization: Case Report and Literature Review
Conclusions: There are limited reports of protamine reversal of heparin before IV-tPA administration. To our knowledge, there are only 6 AIS cases including ours. Three cases received 0.6 mg/kg of tPA dose. All have favorable outcomes and no intracranial hemorrhage was reported. Protamine reversal of heparin for AIS after CC seems to be safe. Further studies are needed to confirm the therapeutic safety and efficacy of this strategy.
Source: The Neurologist - November 1, 2018 Category: Neurology Tags: Case Report/Case Series Source Type: research

Does High Cerebral Microbleed Burden Increase the Risk of Intracerebral Hemorrhage After Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke?
Conclusions: CMBs are associated with an increased risk of postthrombolysis ICH; however, the clinical implications have yet to be determined.
Source: The Neurologist - December 27, 2018 Category: Neurology Tags: Critically Appraised Topics Source Type: research

Sickle Cell Disease and Stroke
Cerebral infarction is a common complication of sickle cell disease (SCD) and may manifest as overt stroke or cognitive impairment associated with ‘silent’ cerebral infarction (SCI) on magnetic resonance imaging (MRI). Vasculopathy may be diagnosed on transcranial Doppler (TCD) or MR angiography (MRA). The risk factors in SCD for cognitive impairment, overt ischemic stroke, SCI, overt hemorrhagic stroke and vasculopathy defined by TCD or M RA overlap, with severe acute and chronic anemia, acute chest crisis, reticulocytosis and low oxygen saturation reported with the majority.
Source: Pediatric Neurology - February 27, 2019 Category: Neurology Authors: Deborah Hirtz, Fenella Kirkham Tags: Review Article Source Type: research

Reliability of fast magnetic resonance imaging for acute ischemic stroke patients using a 1.5-T scanner
ConclusionsFast MRI at 1.5  T is a reliable method for the detection and characterization of acute ischemic stroke in comparison with conventional MRI.Key Points• Fast MRI at 1.5 T may achieve a high intermethod reliability in the detection and characterization of acute ischemic stroke with a reduction in scan time in comparison with conventional MRI.
Source: European Radiology - April 3, 2019 Category: Radiology Source Type: research

Carotid plaque magnetic resonance imaging and recurrent stroke risk: A systematic review and meta-analysis
Conclusions: The presence of intraplaque hemorrhage, lipid-rich necrotic core, and thinning/rupture of the fibrous cap on MRI of carotid plaque are strong predictors of recurrent stroke events. However, due to the lack of original studies, larger cohort studies are warranted.
Source: Medicine - March 1, 2020 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

The Progress of the Gait Impairment and Brain Activation in a Patient with Post-stroke Hemidystonia
CONCLUSION: These results suggest that there was improvement of the patient's symptoms of post-stroke hemidystonia due to changes in the brain activity during voluntary movement after BWS intervention. Body weight-supported treadmill training may thus be an effective treatment for patients with poststroke hemidystonia.PMID:34532214 | PMC:PMC8419483 | DOI:10.1298/ptr.E10032
Source: Physical Therapy - September 17, 2021 Category: Physiotherapy Authors: Satoshi Yamamoto Daisuke Ishii Kyoko Kanae Yusuke Endo Kenichi Yoshikawa Kazunori Koseki Ryo Nakazawa Hanako Takano Masahiko Monma Arito Yozu Akira Matsushita Yutaka Kohno Source Type: research

HSV-Encephalitis Resembling Acute Cerebral Infarction in a Patient With Atrial Fibrillation: Beware of Stroke Mimics
Conclusion: HSV-encephalitis might occasionally result in the development of unilateral brain MRI lesions with extensive cytotoxic edema, resembling an acute ischemic stroke. Therefore, HSV-encephalitis must be considered in the differential diagnosis of acute ischemic stroke with atypical presentation. The presence of a significant dissociation between the brain MRI lesion volume and the neurological deficits, as well as certain brain MRI imaging discrepancies might serve as “red flags” to extend the diagnostic workup.
Source: The Neurologist - January 1, 2022 Category: Neurology Tags: Case Report/Case Series Source Type: research