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Condition: Heart Disease
Procedure: MRI Scan

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Total 96 results found since Jan 2013.

Utility of Duranta, a wireless patch-type electrocardiographic monitoring system developed in Japan, in detecting covert atrial fibrillation in patients with cryptogenic stroke: A case report
Rationale: Subcutaneous implantable electrocardiographs are highly effective in detecting covert atrial fibrillation (AF) in cryptogenic stroke. However, these invasive devices are not indicated for all cryptogenic stroke patients, and noninvasive improvements over conventional Holter-type ambulatory electrocardiography are needed. We evaluated the clinical application and effectiveness of Duranta (ImageONE Co., Ltd.), a wireless patch-type electrocardiographic monitoring system developed in Japan for chronically ill patients or home-based patients at the end of life. A Duranta device was used to detect covert AF in patien...
Source: Medicine - February 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease
Carotid plaque thickness and stenosis are associated with a history of ischemic stroke and coronary heart disease (CHD). Carotid intraplaque hemorrhage is associated with ischemic stroke but not with CHD.
Source: Journal of Vascular Surgery - September 22, 2016 Category: Surgery Authors: M. Selwaness, D. Bos, Q. van den Bouwhuijsen Tags: Abstract Source Type: research

TRAFIP2 in Adverse Cardiac Remodeling Gene Regulation
TRAF3IP2 (TRAF3 interacting protein 2; previously known as CIKS or Act1) is a key intermediate in the normal inflammatory response and the pathogenesis of various autoimmune and inflammatory diseases. Induction of TRAF3IP2 activates IκB kinase (IKK)/NF-κB, JNK/AP-1, and c/EBPβ and stimulates the expression of various inflammatory mediators with negative myocardial inotropic effects. To investigate the role of TRAF3IP2 in heart disease, we generated a transgenic mouse model with cardiomyocyte-specific TRAF3IP2 overexpression (TRAF3IP2-Tg). Echocardiography, magnetic resonance imaging, and pressure-volume conductance cath...
Source: Journal of Biological Chemistry - September 8, 2016 Category: Chemistry Authors: Yariswamy, M., Yoshida, T., Valente, A. J., Kandikattu, H. K., Sakamuri, S. S. V. P., Siddesha, J. M., Sukhanov, S., Saifudeen, Z., Ma, L., Siebenlist, U., Gardner, J. D., Chandrasekar, B. Tags: Molecular Bases of Disease Source Type: research

Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction Gene Regulation
TRAF3IP2 (TRAF3 interacting protein 2; previously known as CIKS or Act1) is a key intermediate in the normal inflammatory response and the pathogenesis of various autoimmune and inflammatory diseases. Induction of TRAF3IP2 activates IκB kinase (IKK)/NF-κB, JNK/AP-1, and c/EBPβ and stimulates the expression of various inflammatory mediators with negative myocardial inotropic effects. To investigate the role of TRAF3IP2 in heart disease, we generated a transgenic mouse model with cardiomyocyte-specific TRAF3IP2 overexpression (TRAF3IP2-Tg). Echocardiography, magnetic resonance imaging, and pressure-volume conductance cath...
Source: Journal of Biological Chemistry - September 8, 2016 Category: Chemistry Authors: Manjunath Yariswamy, Tadashi Yoshida, Anthony J. Valente, Hemanth Kumar Kandikattu, Siva S. V. P. Sakamuri, Jalahalli M. Siddesha, Sergiy Sukhanov, Zubaida Saifudeen, Lixin Ma, Ulrich Siebenlist, Jason D. Gardner, Bysani Chandrasekar Tags: Molecular Bases of Disease Source Type: research

Influence of cerebral white matter hyperintensities on cognitive impairment in elderly medical patients
ConclusionsAlthough cognitive impairment in elderly medical patients is associated with stroke and brain atrophy, white matter hyperintensities, especially BGH and infratentorial region, are associated with cognitive decline in relation to CKD. Geriatr Gerontol Int 2016; ••: ••–••.
Source: Geriatrics and Gerontology International - August 31, 2016 Category: Geriatrics Authors: Koichi Shibata, Yoshiko Nishimura, Kuniaki Otsuka, Hiroshi Sakura Tags: Original Article: Epidemiology, Clinical Practice and Health Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Silent Cerebral Small Vessel Disease in Restless Legs Syndrome
Conclusion:RLS duration should be taken into account when analyzing the association between RLS and cerebrovascular disease; our data support the hypothesis that a long-lasting RLS and its accompanying periodic limb movements in sleep are a risk factor for silent SVD and perhaps for the development of clinical stroke.Citation:Ferri R, Cosentino FI, Moussouttas M, Lanuzza B, Aricò D, Bagai K, Wang L, McLaughlin B, Walters AS. Silent cerebral small vessel disease in restless legs syndrome. SLEEP 2016;39(7):1371–1377.
Source: Sleep - July 1, 2016 Category: Sleep Medicine Source Type: research

Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease Clinical Sciences
Conclusions— Whereas carotid plaque thickness and stenosis are associated with the history of ischemic stroke and CHD, carotid intraplaque hemorrhage is associated with ischemic stroke, but not with CHD, providing novel insights into the pathogenesis of cardiovascular events.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Selwaness, M., Bos, D., van den Bouwhuijsen, Q., Portegies, M. L. P., Ikram, M. A., Hofman, A., Franco, O. H., van der Lugt, A., Wentzel, J. J., Vernooij, M. W. Tags: Cardiovascular Disease, Epidemiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Clinical Sciences Source Type: research

Myocardial triglyceride content in patients with left ventricular hypertrophy: comparison between hypertensive heart disease and hypertrophic cardiomyopathy
We examined whether myocardial TG content assessed by 1H-MRS was useful for diagnosis in patients with LVH. To quantify myocardial TG content, we conducted 1H-MRS in 35 subjects with LVH. Left ventricular function was measured by cardiac magnetic resonance imaging. Patients were assigned to a hypertensive heart disease (HHD, n = 10) or hypertrophic cardiomyopathy (HCM, n = 25) group based on the histology and/or late gadolinium enhancement pattern. The myocardial TG content was significantly higher in the HHD group than in the HCM group (2.14 ± 1.29 vs. 1.09 ± 0.72 %, P < 0.001). Myocardial TG content were ...
Source: Heart and Vessels - May 2, 2016 Category: Cardiology Source Type: research

Left ventricular geometry and white matter lesions in ischemic stroke patients.
Authors: Butenaerts D, Chrzanowska-Wasko J, Slowik A, Dziedzic T Abstract Abnormal left ventricular (LV) geometry is associated with extracardiac organ damage in patients with hypertension. The aim of this study was to determine the relationship between LV geometry and white matter lesions (WMLs) in ischemic stroke patients. We retrospectively analyzed data from 155 patients (median age 62; 49.8% male) with mild ischemic stroke (median National Institutes of Health Stroke Scale score 4) who underwent brain magnetic resonance imaging and echocardiography. Patients were categorized into four groups: normal LV geometr...
Source: Blood Pressure - February 14, 2016 Category: Hematology Tags: Blood Press Source Type: research

Neuropsychological Status and Structural Brain Imaging in Adolescents With Single Ventricle Who Underwent the Fontan Procedure Congenital Heart Disease
Conclusions The neuropsychological deficits and high frequencies of structural brain abnormalities in adolescents who underwent the Fontan procedure highlight the need for research on interventions to improve the long-term outcomes in this high-risk group.
Source: JAHA:Journal of the American Heart Association - December 14, 2015 Category: Cardiology Authors: Bellinger, D. C., Watson, C. G., Rivkin, M. J., Robertson, R. L., Roberts, A. E., Stopp, C., Dunbar-Masterson, C., Bernson, D., DeMaso, D. R., Wypij, D., Newburger, J. W. Tags: Congenital Heart Disease Source Type: research

Increased Silent Brain Infarction Accompanied With High Prevalence of Diabetes and Dyslipidemia in Psychiatric Inpatients: A Cross-Sectional Study.
CONCLUSIONS: Participants in this study had an increased ratio of silent brain infarction compared with Japanese healthy controls, accompanied with higher ratios of diabetes and low HDL cholesterol. PMID: 26445690 [PubMed]
Source: The Primary Care Companion for CNS Disorders - October 9, 2015 Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research

Association of Cerebral Microbleeds with Higher Morbidity and Mortality in Ischemic Stroke? (P1.044)
CONCLUSIONS: Microbleed in ischemic stroke on magnetic resonance imaging scan is associated with higher morbidity and mortality especially in older patients with uncontrolled hypertension and anticoagulant therapy.Disclosure: Dr. Ahad has nothing to disclose. Dr. Ahmed has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Duggal has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ahad, R., Ahmed, I., Lee, G., Duggal, N. Tags: Cerebrovascular Disease and Interventional Neurology: The Spectrum of Small Vessel Cerebrovascular Disease Source Type: research

Cerebral Microbleeds Determine Long-Term Mortality in Acute Ischemic Stroke Patients with Lacunar Subtype (P1.015)
CONCLUSIONS: The presence, multiplicity and distribution of CMBs were associated with increased mortality in lacunar stroke patients. The detection and evaluation of CMBs is of value in predicting long-term prognosis in lacunar stroke patients. Study Supported: None.Disclosure: Dr. Song has nothing to disclose. Dr. Younkyung has nothing to disclose. Dr. Youn has nothing to disclose. Dr. Heo has nothing to disclose. Dr. Kim has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Song, T.-J., Younkyung, C., Youn, M., Heo, J. H., Kim, Y. J. Tags: Cerebrovascular Disease and Interventional Neurology I ePosters Source Type: research

Writing Tremor Secondary to Ischemic Stroke: A Report on a Case With a Remarkable Response to Topiramate
Conclusions: Primary WT pathophysiology is not well known, and secondary WT as a result of stroke is even less considered. Although patients with essential tremor benefit with TPM and WT could be a variant of essential tremor, we used TPM with our patient and there was a marked benefit.
Source: Clinical Neuropharmacology - March 1, 2015 Category: Neurology Tags: Case Reports Source Type: research