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Condition: Brain Tumor

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Total 780 results found since Jan 2013.

Identification of Circulating MicroRNAs as Potential Biomarkers for Detecting Acute Ischemic Stroke.
In conclusion, we identified the changed expression pattern of miRNAs in IS. Serum miR-32-3p, miR-106-5p, miR-1246, and miR-532-5p may serve as potential diagnostic biomarkers for IS. Our results also demonstrate a novel role for miRNAs in the pathogenesis of IS. PMID: 25410304 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Neurobiology - November 20, 2014 Category: Cytology Authors: Li P, Teng F, Gao F, Zhang M, Wu J, Zhang C Tags: Cell Mol Neurobiol Source Type: research

The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer's disease.
Abstract Microglia undergo a process of activation in pathology which is controlled by many factors including neurotransmitters. We found that a subpopulation (11 %) of freshly isolated adult microglia respond to the muscarinic acetylcholine receptor agonist carbachol with a Ca(2+) increase and a subpopulation of similar size (16 %) was observed by FACS analysis using an antibody against the M3 receptor subtype. The carbachol-sensitive population increased in microglia/brain macrophages isolated from tissue of mouse models for stroke (60 %) and Alzheimer's disease (25 %), but not for glioma and multiple sclero...
Source: Brain Structure and Function - December 19, 2014 Category: Neuroscience Authors: Pannell M, Meier MA, Szulzewsky F, Matyash V, Endres M, Kronenberg G, Prinz V, Waiczies S, Wolf SA, Kettenmann H Tags: Brain Struct Funct Source Type: research

A rare case of transient ischemic attacks and acute ischemic stroke from left intracranial arteries encased in meningioma. (P1.021)
CONCLUSIONS:Compression of the intracranial blood vessel is a rare complication of meningioma which can result in TIAs and ischemic stroke.Disclosure: Dr. Tantikittichaikul has nothing to disclose. Dr. Laengvejkal has nothing to disclose. Dr. Eldokla has nothing to disclose. Dr. Kim has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tantikittichaikul, S., Laengvejkal, P., Eldokla, A., Kim, J. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

A Generative Probabilistic Model and Discriminative Extensions for Brain Lesion Segmentation— With Application to Tumor and Stroke
We introduce a generative probabilistic model for segmentation of brain lesions in multi-dimensional images that generalizes the EM segmenter, a common approach for modelling brain images using Gaussian mixtures and a probabilistic tissue atlas that employs expectation-maximization (EM), to estimate the label map for a new image. Our model augments the probabilistic atlas of the healthy tissues with a latent atlas of the lesion. We derive an estimation algorithm with closed-form EM update equations. The method extracts a latent atlas prior distribution and the lesion posterior distributions jointly from the image data. It ...
Source: IEE Transactions on Medical Imaging - March 31, 2016 Category: Biomedical Engineering Source Type: research

Prevalence of epilepsy/seizures as a comorbidity of neurologic disorders in nursing homes
Conclusions: The prevalence of epi/sz in the elderly nursing home population is >7-fold higher compared to community-dwelling elderly and is 7 to 30 times higher among those with certain comorbid neurologic conditions. Demographics and clinical characteristics had weaker associations with epi/sz prevalence.
Source: Neurology - February 19, 2017 Category: Neurology Authors: Birnbaum, A. K., Leppik, I. E., Svensden, K., Eberly, L. E. Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Brain trauma, Prevalence studies, All Epilepsy/Seizures ARTICLE Source Type: research

Keeping up with Amanda: Life after brain surgery
In most ways, Amanda LePage is just like any other rambunctious fourth grader. She loves school, dance class, playing basketball and keeping up with her twin sister Macy and older brother Nathan. Sometimes it just takes her a little longer to do these everyday things. That’s because Amanda has been through a lot in her short nine years. Amanda was just 5 months old when she was brought by helicopter to Boston Children’s Hospital for a hemorrhage in her brain from an intracranial aneurysm, a type of vascular malformation. Despite long odds, Amanda survived two life-saving brain surgeries and a massive stroke that left ...
Source: Thrive, Children's Hospital Boston - May 22, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Our Patients’ Stories brain aneurysm Dr. Caroline Robson Dr. Craig McClain Dr. Edward Smith Dr. Peter Manley Hydrocephalus low-grade glioma pediatric stroke Source Type: news

Incidence and impact of stroke following surgery for low-grade gliomas.
CONCLUSIONS: Recurrent surgeries and insular tumor locations are risk factors for intraoperative strokes. Although they do not affect survival, these strokes negatively affect patient activity and performance status, mainly during the first 3 postoperative months, with gradual functional improvement over 1 year. Several intraoperative parameters may suggest the impending development of an infarct. PMID: 31881532 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - December 26, 2019 Category: Neurosurgery Authors: Berger A, Tzarfati G, Costa M, Serafimova M, Korn A, Vendrov I, Alfasi T, Krill D, Aviram D, Ben Moshe S, Kashanian A, Ram Z, Grossman R Tags: J Neurosurg Source Type: research

Stroke-like migraine attacks after radiation therapy (SMART) syndrome —a case series and review
ConclusionOur extensive review favors MRI, CT, and prolonged EEG monitoring to rule out other differentials and showed that initiation of corticosteroid therapy and antiepileptic treatment were helpful in the resolution of symptoms and prevent recurrences. Therefore, future studies should be focused on early identification and management guidelines for SMART syndrome.
Source: Neurological Sciences - July 12, 2020 Category: Neurology Source Type: research

The Cerebral Microvasculature: Basic and Clinical Perspectives on Stroke and Glioma
AbstractMicrovascular networks are vital components of the cardiovascular system, performing many key roles in maintaining the health and homeostasis of the tissues and organs in which they develop. As discussed in this review, the molecular and cellular components within the microcirculation orchestrate critical processes to establish functional capillary beds, including organization of endothelial cell (EC) polarity, guiding investment of vascular pericytes (PCs), and building the specialized extracellular matrix (ECM) that comprises the vascular basement membrane (vBM). Herein, we further discuss the unique features of ...
Source: Microcirculation - November 10, 2020 Category: Research Authors: Maruf M. Hoque, Hanaa Abdelazim, Clifton Jenkins ‐Houk, Dawn Wright, Biraj M. Patel, John C. Chappell Tags: INVITED REVIEW Source Type: research

Strangled by Dr Strangelove? Anarchic hand following a posterior cerebral artery territory ischemic stroke
We present a case of a 74-year-old man who developed an anarchic right hand following thrombolysis for a posterior cerebral artery territory ischemic stroke.
Source: Age and Ageing - July 16, 2020 Category: Geriatrics Source Type: research

The cerebral microvasculature: Basic and clinical perspectives on stroke and glioma
AbstractMicrovascular networks are vital components of the cardiovascular system, performing many key roles in maintaining the health and homeostasis of the tissues and organs in which they develop. As discussed in this review, the molecular and cellular components within the microcirculation orchestrate critical processes to establish functional capillary beds, including organization of endothelial cell (EC) polarity, guiding investment of vascular pericytes (PCs), and building the specialized extracellular matrix (ECM) that comprises the vascular basement membrane (vBM). Herein, we further discuss the unique features of ...
Source: Microcirculation - November 23, 2020 Category: Research Authors: Maruf M. Hoque, Hanaa Abdelazim, Clifton Jenkins ‐Houk, Dawn Wright, Biraj M. Patel, John C. Chappell Tags: INVITED REVIEWS Source Type: research

Acute ischemic stroke secondary to ventriculoperitoneal shunt dysfunction in a child with Moyamoya syndrome
CONCLUSION: Children who receive RT for brain tumor, particularly if the circle of Willis region is involved, require close surveillance for the development of vasculopathy and consequent stroke. This surveillance must be even tighter if the patient has been treated with ventricular shunt for the possible synergistic interaction between the two causes on reducing cerebral perfusion and increasing the risk of acute ischemic events.PMID:35928308 | PMC:PMC9345112 | DOI:10.25259/SNI_434_2022
Source: Surgical Neurology International - August 5, 2022 Category: Neurosurgery Authors: Francesca Vitulli Pietro Spennato Domenico Cicala Giuseppe Mirone Maria Rosaria Scala Giuseppe Cinalli Source Type: research