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Condition: Encephalitis
Infectious Disease: COVID-19

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Total 398 results found since Jan 2013.

COVID-19 may also invade the central nervous system, cause neurological illnesses
(Cleveland Clinic) COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia. Now, Cleveland Clinic researchers note in a recent review that infection with the coronavirus may also affect the central nervous system and cause corresponding neurological disorders, including ischemic stroke, encephalitis, encephalopathy and epileptic seizures.According to the review published in Cells, the symptoms of COVID-19-related neurological manifestations include dizziness, headache, a loss of consciousness and ataxia.
Source: EurekAlert! - Infectious and Emerging Diseases - December 10, 2020 Category: Infectious Diseases Source Type: news

Case Report: Postacute Rehabilitation of Guillain-Barr é Syndrome and Cerebral Vasculitis-Like Pattern Accompanied by SARS-CoV-2 Infection
Conclusion: In this report, we present the case of a patient with peripheral and central neurological damage occurred later severe pneumonia induced by SARS-CoV-2. The Immunoglobulin G therapy allowed the patient to benefit considerably from early rehabilitation, reaching the walking, increasing the independence in daily living tasks, and enabling safe discharge from hospital to home. Related neurologic complications of SARS-CoV-2 infection suffer a lack of understanding and further investigations should be conducted.
Source: Frontiers in Neurology - January 7, 2021 Category: Neurology Source Type: research

Central and peripheral nervous system complications of COVID-19: a prospective tertiary center cohort with 3-month follow-up
ConclusionCNS  and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral neurotropism were detected, but laboratory changes suggested autoimmune-mediate d mechanisms.
Source: Journal of Neurology - January 13, 2021 Category: Neurology Source Type: research

Neurological Complications of the COVID-19 Pandemic: What Have We Got So Far?
Adv Exp Med Biol. 2021;1321:21-31. doi: 10.1007/978-3-030-59261-5_2.ABSTRACTThe recently emerged coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19, is the newest threat to human health. It has already infected more than 54.5 million people worldwide, currently leading to more than 1.3 million deaths. Although it causes a mild flu-like disease in most patients, lethality may increase to more than 20% in elderly subjects, especially in those with comorbidities, like hypertension, diabetes, or lung and cardiac disease, and the mechanisms are still elusive. Common symp...
Source: Advances in Experimental Medicine and Biology - March 3, 2021 Category: Research Authors: Isabelle Pastor Bandeira Marco Ant ônio Machado Schlindwein Leticia Caroline Breis Jean Pierre Schatzmann Peron Marcus Vin ícius Magno Gonçalves Source Type: research

Neuropsychiatric Symptoms of COVID-19 Explained by SARS-CoV-2 Proteins ’ Mimicry of Human Protein Interactions
Conclusion: SARS-CoV-2-human protein interactions may lead to the development of delirium, psychosis, seizures, encephalitis, stroke, sensory impairments, peripheral nerve diseases, and autoimmune disorders. Our findings are also supported by the previous in vivo and in vitro studies from other viruses. Further in vivo and in vitro studies using the proteins that are pointed here, could pave new targets both for avoiding and reversing neuropsychiatric presentations.
Source: Frontiers in Human Neuroscience - March 23, 2021 Category: Neuroscience Source Type: research

Acute Fulminant Cerebellitis in Paediatric COVID-19 Infection- rare, yet a potentially treatable clinical entity
This past year, coronavirus disease 2019 (COVID-19) has displayed widespread systemic manifestations including neurological features (upto 36%) such as stroke, myelitis and encephalitis.1,2 We would like to draw attention to two cases of paediatric COVID-19-associated acute fulminant cerebellitis and discuss treatment challenges.
Source: Pediatric Neurology - March 24, 2021 Category: Neurology Authors: Sanjiv Sharma, Jigish Ruparelia, Suryanarayanan Bhaskar, Sarbesh Tiwari, Vijaya Lakshmi Nag, Samhita Panda Tags: Short Communication Source Type: research

Severe Neurologic Complications of SARS-CoV-2
We present readers with a review of the literature of severe neurologic complications of SARS-CoV-2 and cases from our institution to illustrate these conditions.Recent FindingsNeurologic manifestations are being increasingly recognized in the literature. Some patients can have severe neurologic manifestations, though the true prevalence is unknown.SummarySevere neurologic complications of COVID-19 include large vessel occlusion ischemic stroke, intracranial hemorrhage, encephalitis, myelitis, Guillain-Barre syndrome, status epilepticus, posterior reversible encephalopathy syndrome, and hypoxic-ischemic encephalopathy. The...
Source: Current Treatment Options in Neurology - March 31, 2021 Category: Neurology Source Type: research

Neurologic aspects of coronavirus disease of 2019 infection
Purpose of review Central and peripheral nervous system manifestations of coronavirus disease 2019 (COVID-19) have been frequently reported and may cause significant morbidity and mortality. This review details the latest evidence on the neuropathogenesis and neurologic complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Recent findings Commonly reported neurologic complications include toxic-metabolic encephalopathy, acute cerebrovascular disorders, seizures, and anoxic-brain injury. These complications represent secondary injury due to COVID-19 related hypoxia, sepsis, hype...
Source: Current Opinion in Infectious Diseases - May 2, 2021 Category: Infectious Diseases Tags: CNS INFECTIONS: Edited by Adarsh Bhimraj Source Type: research

Demyelination as a result of an immune response in patients with COVID-19
AbstractThe coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2), that already appeared as a global pandemic. Presentation of the disease often includes upper respiratory symptoms like dry cough, dyspnea, chest pain, and rhinorrhea that can develop to respiratory failure, needing intubation. Furthermore, the occurrence of acute and subacute neurological manifestations such as stroke, encephalitis, headache, and seizures are frequently stated in patients with COVID-19. One of the reported neurological complications of severe COVID-19 is the demolition of the my...
Source: Acta Neurologica Belgica - May 2, 2021 Category: Neurology Source Type: research

Acute Fulminant Cerebellitis in Children with COVID-19 Infection: A Rare But Treatable Complication
The past year, coronavirus disease 2019 (COVID-19) has displayed widespread systemic manifestations including neurological features (up to 36%) such as stroke, myelitis, and encephalitis.1,2 We draw attention to two children with COVID-19-associated acute fulminant cerebellitis and discuss the treatment challenges.
Source: Pediatric Neurology - March 24, 2021 Category: Neurology Authors: Sanjiv Sharma, Jigish Ruparelia, Suryanarayanan Bhaskar, Sarbesh Tiwari, Vijaya Lakshmi Nag, Samhita Panda Tags: Clinical Letter Source Type: research

Neurologic Manifestations of COVID-19
Adv Exp Med Biol. 2021;1318:343-353. doi: 10.1007/978-3-030-63761-3_20.ABSTRACTNeurological manifestations of novel coronavirus disease (COVID-19) are reported to occur in as much as 37% of the affected patients. These manifestations range from headache and dizziness to altered mental status and consciousness, anosmia, ageusia, sensory disturbances, and stroke. The mechanisms by which the neurological symptoms arise are not yet determined but may either proceed as an indirect consequence of systemic hyperinflammation or result from the direct invasion of the virus to neural and glial cells. The neural invasion can explain ...
Source: Advances in Experimental Medicine and Biology - May 11, 2021 Category: Research Authors: Farnaz Delavari Farnaz Najmi Varzaneh Nima Rezaei Source Type: research