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Condition: Encephalitis
Infectious Disease: COVID-19

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Total 398 results found since Jan 2013.

COVID-19 encephalitis with SARS-CoV-2 detected in cerebrospinal fluid presenting as a stroke mimic
We report the case of a 35-year-old male with COVID-19 encephalitis presenting as a stroke mimic with sudden-onset expressive and receptive dysphasia, mild confusion and right arm incoordination. The patient received thrombolysis for a suspected ischaemic stroke, but later became febrile and SARS-CoV-2 was detected in cerebrospinal fluid. Electroencephalography demonstrated excess in slow waves, but neuroimaging was reported as normal. Respiratory symptoms were absent throughout and nasopharyngeal swab was negative for SARS-CoV-2.
Source: Journal of Stroke and Cerebrovascular Diseases - May 30, 2021 Category: Neurology Authors: Diarmuid Glavin, Denise Kelly, Greta Karen Wood, Beth MS McCausland, Mark Alexander Ellul, Aravinthan Varatharaj, Ian Galea, Rhys Huw Thomas, Benedict Daniel Michael, Brian Gallen, CoroNerve Study Management Group Tags: Case Report Source Type: research

COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exception —A Systematic Review
This study provides a comprehensive review of the pathobiology of COVID-19 and ischemic stroke. It also affirms that the immunological contribution to the pathophysiology of COVID-19 is predictive of the neurological sequelae particularly ischemic stroke, which makes it the expectation rather than the exception. This work is of fundamental significance to the neurorehabilitation community given the increasing number of COVID-related ischemic strokes, the current limited knowledge regarding the risk of reinfection, and recent reports of a PCNS. It further highlights the need for global collaboration and research into new pa...
Source: Frontiers in Neurology - January 28, 2021 Category: Neurology Source Type: research

Intraluminal carotid thrombosis and acute ischemic stroke associated with COVID-19
AbstractCOVID-19 (Coronavirus disease 2019) caused by SARS-CoV-2 has a diverse constellation of neurological manifestations that include encephalopathy, stroke, Guillain –Barré syndrome, myelitis, and encephalitis. Intraluminal carotid thrombi (ILT) are infrequent lesions seen in only 1.6% of patients with acute ischemic stroke. Underlying atherosclerosis is the most common lesion associated with ILT formation. However, with COVID-19, we have encountered ILT in p atients without significant atherosclerotic disease. The endothelial inflammation and hypercoagulable state associated with COVID-19 pose a risk of arterial an...
Source: Journal of Neurology - November 3, 2021 Category: Neurology Source Type: research

Neurological emergencies associated with COVID-19: stroke and beyond
We report five cases of COVID-19 presenting to the ER with acute neurological symptoms, over the course of 1  month. This includes two cases of ischemic stroke, one with large-vessel occlusion and one with embolic infarcts. The remainders of the cases include acute tumefactive demyelination, isolated cytotoxic edema of the corpus callosum with subarachnoid hemorrhage, and posterior reversible encephalopat hy syndrome (PRES).
Source: Emergency Radiology - August 10, 2020 Category: Emergency Medicine Source Type: research

COVID-19 induced ischemic stroke and mechanisms of viral entry in brain and clot formation: a systematic review and current update
Conclusion: Data available in the literature is not adequate to come to a conclusion. Therefore, there is a need to carry out further studies to delineate the possible association between SCV-2 induced IS.PMID:35412938 | DOI:10.1080/00207454.2022.2056460
Source: Atherosclerosis - April 12, 2022 Category: Cardiology Authors: Abhilash Ludhiadch Swaraj Ranjan Paul Rahul Khan Anjana Munshi Source Type: research

CNS inflammatory vasculopathy with antimyelin oligodendrocyte glycoprotein antibodies in COVID-19
A 44-year-old right-handed woman reported a gradual onset of right hand incoordination seven days after the onset of minor respiratory symptoms and pruritus due to COVID-19 infection. Over 48 hours, the patient developed word-finding difficulties and progression in right arm weakness leading to presentation to the emergency department as a suspected stroke.
Source: Neurology Neuroimmunology and Neuroinflammation - June 9, 2020 Category: Neurology Authors: Pinto, A. A., Carroll, L. S., Nar, V., Varatharaj, A., Galea, I. Tags: MRI, Other cerebrovascular disease/ Stroke, Encephalitis, COVID-19 Clinical/Scientific Notes Source Type: research

Posterior Reversible Encephalopathy Syndrome in Patients with Coronavirus Disease 2019: Two Cases and a Review of the Literature
Central nervous system (CNS) manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection include encephalopathy, encephalitis, meningitis, acute disseminated encephalomyelitis, and stroke [1], both as a result of direct viral invasion of the central nervous system [2 –5] and as a consequence of critical illness and systemic infection [6]. Coronavirus disease 2019 (COVID-19) may also cause significant changes in endothelial morphology, including disruption of intercellular junctions, cell swelling, and a loss of contact with the basal membrane [7].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2020 Category: Neurology Authors: Pria Anand, K. H.Vincent Lau, David Y Chung, Deepti Virmani, Anna M. Cervantes-Arslanian, Asim Mian, Courtney E. Takahashi Source Type: research

Presentations and mechanisms of CNS disorders related to COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the coronavirus disease 2019 (COVID-19) pandemic. In addition to severe respiratory symptoms, there are a growing number of reports showing a wide range of CNS complications in patients with COVID-19. Here, we review the literature on these complications, ranging from nonspecific symptoms to necrotizing encephalopathies, encephalitis, myelitis, encephalomyelitis, endotheliitis, and stroke. We postulate that there are several different mechanisms involved in COVID-19–associated CNS dysfunction, particularly activation of inflammatory and thro...
Source: Neurology Neuroimmunology and Neuroinflammation - December 11, 2020 Category: Neurology Authors: Bodro, M., Compta, Y., Sanchez-Valle, R. Tags: Other cerebrovascular disease/ Stroke, Encephalitis, COVID-19 Views [amp ] Reviews Source Type: research

Acute ischemic stroke in a pediatric patient with known exposure to COVID-19 and positive serology
Neurologic manifestations of COVID-19 in pediatrics are not well understood. Recently, Kaur et al. reported a child with transverse myelitis and McAbee et al. described a child with seizures and encephalitis, in the setting of an acute COVID-19 infection.1,2 Acute ischemic stroke (AIS) and focal cerebral arteriopathy have also been reported.3
Source: Pediatric Neurology - December 14, 2020 Category: Neurology Authors: Min Ye Shen, Rachelle Dugue, Angel R. Maldonado-Soto, Kiran T. Thakur, Israel Zyskind, Wendy S. Vargas Tags: Correspondence Source Type: research

Neurological Sequelae of COVID-19
J Integr Neurosci. 2022 Apr 6;21(3):77. doi: 10.31083/j.jin2103077.ABSTRACTBACKGROUND: Though primarily a pulmonary disease, Coronavirus disease 2019 (COVID-19) caused by the SARS-CoV-2 virus can generate devastating disease states that affect multiple organ systems including the central nervous system (CNS). The various neurological disorders associated with COVID-19 range in severity from mild symptoms such as headache, or myalgias to more severe symptoms such as stroke, psychosis, and anosmia. While some of the COVID-19 associated neurological complications are mild and reversible, a significant number of patients suffe...
Source: Journal of Integrative Neuroscience - May 28, 2022 Category: Neuroscience Authors: Samuel J Ahmad Chaim M Feigen Juan P Vazquez Andrew J Kobets David J Altschul Source Type: research