Filtered By:
Specialty: Cardiology
Condition: Bleeding

This page shows you your search results in order of date. This is page number 4.

Order by Relevance | Date

Total 3637 results found since Jan 2013.

Preferred monotherapy after short-term dual antiplatelet therapy: Systematic review and network meta-analysis of randomized trials
CONCLUSIONS: Compared with aspirin monotherapy following short-term DAPT, ticagrelor following 3-month DAPT was associated with a reduced risk of primary bleeding outcomes without increasing any ischemic outcomes.PMID:37562542 | DOI:10.1016/j.jjcc.2023.08.001
Source: Journal of Cardiology - August 10, 2023 Category: Cardiology Authors: Satoshi Shoji Toshiki Kuno Hiroki Ueyama Hisato Takagi Alexandros Briasoulis Hyo-Soo Kim Bon-Kwon Koo Jeehoon Kang Hirotoshi Watanabe Takeshi Kimura Shun Kohsaka Source Type: research

Preferred monotherapy after short-term dual antiplatelet therapy: Systematic review and network Meta-analysis of randomized trials
CONCLUSIONS: Compared with aspirin monotherapy following short-term DAPT, ticagrelor following 3-month DAPT was associated with a reduced risk of primary bleeding outcomes without increasing any ischemic outcomes.PMID:37562542 | DOI:10.1016/j.jjcc.2023.08.001
Source: Journal of Cardiology - August 10, 2023 Category: Cardiology Authors: Satoshi Shoji Toshiki Kuno Hiroki Ueyama Hisato Takagi Alexandros Briasoulis Hyo-Soo Kim Bon-Kwon Koo Jeehoon Kang Hirotoshi Watanabe Takeshi Kimura Shun Kohsaka Source Type: research

Lower-adherence direct oral anticoagulant use is associated with increased risk of thromboembolic events than warfarin
ConclusionsIn this large real-world study, low adherence DOAC was associated with higher risk of TE events as compared to high and low adherence warfarin.
Source: Journal of Interventional Cardiac Electrophysiology - August 9, 2023 Category: Cardiology Source Type: research

Dual Antiplatelet Therapies and Causes in Minor Stroke or Transient Ischemic Attack: A Prespecified Analysis in the CHANCE-2 Trial
CONCLUSIONS: In this prespecified analysis of the CHANCE-2 trial, the efficacy and safety of ticagrelor-aspirin versus clopidogrel-aspirin in preventing new stroke were consistent in patients with different causes. The influence of stroke cause on benefit of gene-guided antiplatelet therapy should be explored by further trials.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT04078737.PMID:37548009 | DOI:10.1161/STROKEAHA.122.042233
Source: Atherosclerosis - August 7, 2023 Category: Cardiology Authors: Xuewei Xie Jing Jing Xia Meng S Claiborne Johnston Philip M Bath Zixiao Li Xingquan Zhao Liping Liu Yilong Wang Qin Xu Anxin Wang Yong Jiang Hao Li Yongjun Wang CHANCE-2 Investigators Source Type: research

Antithrombotic Medication and Major Complications After Mechanical Aortic Valve Replacement
Patients with mechanical aortic valve replacement (AVR) require lifelong vitamin K antagonist (VKA) therapy for stroke and systemic embolism prevention. However, VKA treatment predisposes patients to various types of bleeding. In the present study, we sought to assess the success of antithrombotic therapy and the occurrence and timing of strokes and bleeding events after mechanical AVR. A total of 308 patients who underwent isolated mechanical AVR were included in the study, and follow-up data were completed for 306 patients (99.4%).
Source: The American Journal of Cardiology - August 5, 2023 Category: Cardiology Authors: Rikhard Bj örn, Joonas Lehto, Markus Malmberg, Vesa Anttila, K.E. Juhani Airaksinen, Jarmo Gunn, Tuomas Kiviniemi Source Type: research

5-year Stroke Rates in Nonvalvular Atrial Fibrillation after Watchman compared to Direct Oral Anticoagulants
CONCLUSION: Even in a high-risk population, the WATCHMAN is comparable to DOAC therapy in the primary prevention of hemorrhagic strokes and may provide benefit in the rates of bleeding events, TIAs, and ischemic strokes.PMID:37541428 | DOI:10.1016/j.jjcc.2023.07.015
Source: Journal of Cardiology - August 4, 2023 Category: Cardiology Authors: Syed I Khalid Shyama Sathianathan Kyle B Thomson Laura Stone McGuire Mona C Soni Ankit I Mehta Source Type: research

LAAO Tied to Fewer Post-Fall Bleeds Than DOACs in AF LAAO Tied to Fewer Post-Fall Bleeds Than DOACs in AF
Left atrial appendage occlusion was associated with fewer injuries and less bleeding from falls in patients with atrial fibrillation and previous stroke, compared with oral anticoagulation.Medscape Medical News
Source: Medscape Cardiology Headlines - August 3, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Ticagrelor or Clopidogrel as Antiplatelet Agents in Patients with Chronic Kidney Disease and Cardiovascular Disease: A Meta-analysis
ConclusionsWhen compared with clopidogrel, even though ticagrelor was not associated with higher risk of adverse cardiovascular outcomes in these patients with CKD, it was associated with significantly higher BARC bleeding. Therefore, the safety outcomes of ticagrelor still require further evaluation in patients with CKD. Nevertheless, this hypothesis should only be confirmed with more powerful results that could usually only be achieved using large-scale randomized trials.
Source: American Journal of Cardiovascular Drugs - August 2, 2023 Category: Cardiology Source Type: research

Clinical profiles and one-year outcome in middle eastern patients with atrial fibrillation and major bleeding events. The Jordan atrial fibrillation study
Background and Aims: Oral anticoagulant agents (OACs) reduce the risk of stroke and systemic embolism (SE) in patients with atrial fibrillation (AF) but may increase the risk of major bleeding (MB) events. There is a scarcity of studies that address the incidence, predictors, and outcomes of bleeding events in AF patients in the Middle East. This contemporary multicenter study sought to evaluate in detail the bleeding events and predictors of these events
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: A. Hammoudeh, Y. Khader, Y. Badaineh, R. Tabbalat, S. Rawashdeh, M. Jammal, S. Abrumman, I. Alhaddad Source Type: research

A meta-analysis evaluating efficacy and safety of colchicine for prevention of major cardiovascular events in patients with coronary artery disease
ConclusionsColchicine is an effective, relatively safe drug that could be considered for the treatment of CAD. However, we need to pay attention to the increasing occurrence of non-cardiovascular mortality and infection especially pneumonia possibly caused by colchicine.Graphical abstractEfficacy and safety of colchicine for patients with CAD.CAD coronary artery disease;RCTs randomized controlled trials;OR odds ratio;MACEs major adverse cardiovascular events;ACS acute coronary syndrome;NNT number needed to treat;NNH number needed to harm
Source: Clinical Research in Cardiology - July 28, 2023 Category: Cardiology Source Type: research

Quest for the Perfect Anticoagulant
The current referenced meta-analysis study by Selvaraj et al1 examines the relative merits of anticoagulation with a direct oral anticoagulant (DOAC) versus vitamin K antagonist (VKA) after transcatheter aortic valve implantation (TAVI) in patients meeting the indications for anticoagulation because of atrial fibrillation (AF). Although guidelines vary, the general consensus appears to indicate noninferiority to superiority of DOACs in the treatment of nonvalvular AF. In the landmark Apixiban for Reduction In Stroke and Other Thromboemoblic Events in Atrial Fibrillation trial comparing apixaban to warfarin in patients with...
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Bryant Fisher, Danny Chu Source Type: research

Direct current cardioversion practices following percutaneous left atrial appendage closure
DiscussionThere is a widely varied practice pattern of TEE, CCTA, and OAC use with DCCV after LAAC, with a 6% rate of LAT/DRT. LAA imaging before DCCV appears prudent in all cases, especially within 1 year of LAAC, to assess for device position, PDL, and LAT/DRT.
Source: Journal of Cardiovascular Electrophysiology - July 26, 2023 Category: Cardiology Authors: Sapan Bhuta, Adnan Shaaban, Nkongho C. Binda, James Antaki, Ralph S. Augostini, Steven J. Kalbfleisch, Salvatore J. Savona, Toshimasa Okabe, Mahmoud Houmsse, Muhammad R. Afzal, Emile G. Daoud, John D. Hummel Tags: ORIGINAL ARTICLE Source Type: research

Relationship Between Direct Oral Anticoagulant Doses and Clinical Outcomes in Elderly Patients With Non-Valvular Atrial Fibrillation 　- ANAFIE Registry Sub-Analysis
CONCLUSIONS: Inappropriate low DOAC doses (under- or off-label dose) were not associated with stroke/SEE or major bleeding but were associated with all-cause death.PMID:37482411 | DOI:10.1253/circj.CJ-23-0143
Source: Circulation Journal - July 23, 2023 Category: Cardiology Authors: Masaharu Akao Hiroshi Inoue Takeshi Yamashita Hirotsugu Atarashi Takanori Ikeda Yukihiro Koretsune Ken Okumura Shinya Suzuki Hiroyuki Tsutsui Kazunori Toyoda Atsushi Hirayama Masahiro Yasaka Takenori Yamaguchi Satoshi Teramukai Tetsuya Kimura Yoshiyuki Mo Source Type: research