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Condition: Rhabdomyolysis

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Total 128 results found since Jan 2013.

Challenging Return to Play Decisions: Heat Stroke, Exertional Rhabdomyolysis, and Exertional Collapse Associated With Sickle Cell Trait
Conclusion: With a better understanding of the pathophysiology of EHS, ER, and ECAST and the factors associated with recovery, better decisions regarding return to play may be made.
Source: Sports Health - February 19, 2016 Category: Sports Medicine Authors: Asplund, C. A., OConnor, F. G. Tags: Focus Topic: Wilderness/Extreme Athlete Source Type: research

Transcatheter valve‐in‐ring implantation of a repositionable valve system for treatment of severe mitral regurgitation
ConclusionTransapical valve‐in‐ring implantation of the repositionable Lotus valve system in the mitral position is a feasible and promising option that merits further evaluation. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - December 23, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Michael Lauterbach, Bruno Sontag, Alexandros Paraforos, Ivar Friedrich, Karl‐Eugen Hauptmann Tags: Valvular and Structural Heart Diseases Source Type: research

Transcatheter valve ‐in‐ring implantation of a repositionable valve system for treatment of severe mitral regurgitation
ConclusionTransapical valve‐in‐ring implantation of the repositionable Lotus valve system in the mitral position is a feasible and promising option that merits further evaluation. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - December 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Michael Lauterbach, Bruno Sontag, Alexandros Paraforos, Ivar Friedrich, Karl ‐Eugen Hauptmann Tags: E ‐Only: Valvular and Structural Heart Diseases Source Type: research

Exertional Heat Stroke and Susceptibility to Malignant Hyperthermia in an Athlete: Evidence for a Link?
CONCLUSIONS:  Common features are shared by EHS and MH. Careful attention must therefore be paid to athletes who experience EHS, especially in temperate climates or when there are no other predisposing factors. PMID: 26565425 [PubMed - as supplied by publisher]
Source: J Athl Train - November 13, 2015 Category: Sports Medicine Authors: Poussel M, Guerci P, Kaminsky P, Heymonet M, Roux-Buisson N, Faure J, Fronzaroli E, Chenuel B Tags: J Athl Train Source Type: research

Statins for Primary Prevention of Cardiovascular Disease in Elderly Patients: Systematic Review and Meta-Analysis
Conclusions From a risk–benefit perspective, there is a role of statins for the primary prevention of major adverse cardiovascular events in elderly patients. Further studies are needed to ascertain the benefits of statins on fatal MI, stroke and all-cause mortality.
Source: Drugs and Aging - August 6, 2015 Category: Geriatrics Source Type: research

An unusual case of dengue infection presenting with hypokalemic paralysis with hypomagnesemia
Dengue is the most common arboviral disease prevalent mainly in tropical and subtropical regions [1,2]. It is caused by four serotypes, belonging to family flaviviridae [2]. Dengue can have diverse presentation, from asymptomatic infection to undifferentiated fever, dengue fever, dengue hemorrhagic fever, or dengue shock syndrome [1,3]. Neurological manifestations although rare, may include encephalopathy, meningoencephalitis, myositis, rhabdomyolysis, myelitis, stroke, hypokalemic paralysis, Guillain Barre Syndrome, papilledema, acute disseminated encephalomyelitis, neuromyelitis optica and optic neuritis [4,5].
Source: Journal of Clinical Virology - June 26, 2015 Category: Virology Authors: Rajendra Singh Jain, DM Neurology, Professor, Department of Neurology, SMSMedical College, Jaipur, Rajasthan Tags: Case Report Source Type: research

Biomarkers of multiorgan injury in a preclinical model of exertional heat stroke
It is likely that the pathophysiology of exertional heat stroke (EHS) differs from passive heat stroke (PHS), but this has been difficult to verify experimentally. C57Bl/6 mice were instrumented with temperature transponders and underwent 3 wk of training using voluntary and forced running wheels. An EHS group was exposed to environmental temperatures (Tenv) of 37.5, 38.5, or 39.5°C at either 30, 50, or 90% relative humidities (RH) while exercising on a forced running wheel. Results were compared with sham-matched exercise controls (EXC) and naïve controls (NC). In EHS, mice exercised in heat until they reached li...
Source: Journal of Applied Physiology - May 15, 2015 Category: Physiology Authors: King, M. A., Leon, L. R., Mustico, D. L., Haines, J. M., Clanton, T. L. Tags: ARTICLES Source Type: research

Predictors of Poor Outcome in Neuroleptic Malignant Syndrome: Retrospective Analysis of Nationwide Inpatient Sample (S32.006)
CONCLUSIONS: In patients admitted for neuroleptic malignant syndrome, every decade increment in age, acute kidney injury, seizures and respiratory failure were positive predictors of poor outcome. Every calendar year increase was a negative predictor of poor outcome. Study Supported by:Disclosure: Dr. Modi has nothing to disclose. Dr. Dharaiya has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Modi, S., Dharaiya, D. Tags: Movement Disorders: Tremor, Ataxia, and More Platform Blitz Source Type: research

Acute presentations of inherited metabolic disorders: investigation and initial management
Inborn errors of metabolism are individually rare but so many have now been described that the general paediatrician will encounter one from time to time. For many, early treatment is important. Unfortunately most that present acutely do so with non-specific symptoms and signs. It is therefore necessary to identify and investigate those at high risk. The most common problems are neurological (including coma, seizures and stroke-like episodes), hypoglycaemia, disorders of acid-base regulation, acute liver disease, rhabdomyolysis, cardiomyopathy and sudden collapse.
Source: Paediatrics and Child Health - November 4, 2014 Category: Pediatrics Authors: A.A.M. Morris, J.V. Leonard Tags: Symposium: inborn errors of metabolism Source Type: research

Heat-related illness in sports and exercise
Abstract Exertional heat-related illness (EHRI) is comprised of several states that afflict physically active persons when exercising during conditions of high environmental heat stress. Certain forms of EHRI may become life threatening if not treated. Exertional heat stroke (EHS), characterized by a core body temperature of >40 ° C and mental status changes, is the most severe form of EHRI. EHS must be treated immediately with rapid body cooling to reduce morbidity and mortality. Many EHRI cases are preventable by following heat acclimatization guidelines, modifying sports and exercise sessions during condit...
Source: Current Reviews in Musculoskeletal Medicine - September 21, 2014 Category: Orthopaedics Source Type: research

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis.
Abstract BACKGROUND: Cardiovascular disease (CVD) is the most frequent cause of death in people with early stages of chronic kidney disease (CKD), for whom the absolute risk of cardiovascular events is similar to people who have existing coronary artery disease. This is an update of a review published in 2009, and includes evidence from 27 new studies (25,068 participants) in addition to the 26 studies (20,324 participants) assessed previously; and excludes three previously included studies (107 participants). This updated review includes 50 studies (45,285 participants); of these 38 (37,274 participants) were met...
Source: Sao Paulo Medical Journal - September 4, 2014 Category: Journals (General) Authors: Palmer SC, Navaneethan SD, Craig JC, Johnson DD, Perkovic V, Hegbrant J, Strippoli GF Tags: Sao Paulo Med J Source Type: research

'More adults should be taking statins,' says NICE
Conclusion Despite somewhat hysterical media coverage to the contrary ("millions more to be given statins," according to the Daily Express), nobody will be forced to take statins. If your GP does recommend statins, you should ask them to explain the benefits and risks for you personally of starting statin treatment. You may want to find out more about statins before making up your mind – the NHS Choices Health A-Z information on statins is a good place to start. If you do experience troublesome side effects while taking statins, contact your GP or the doctor in charge of your care. It could be the case that a...
Source: NHS News Feed - July 18, 2014 Category: Consumer Health News Tags: Heart/lungs Medication QA articles Source Type: news

HMG CoA reductase inhibitors (statins) for people with chronic kidney disease not requiring dialysis.
CONCLUSIONS: Statins consistently lower death and major cardiovascular events by 20% in people with CKD not requiring dialysis. Statin-related effects on stroke and kidney function were found to be uncertain and adverse effects of treatment are incompletely understood. Statins have an important role in primary prevention of cardiovascular events and mortality in people who have CKD. PMID: 24880031 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - June 3, 2014 Category: Journals (General) Authors: Palmer SC, Navaneethan SD, Craig JC, Johnson DW, Perkovic V, Hegbrant J, Strippoli GF Tags: Cochrane Database Syst Rev Source Type: research

Clearance of myoglobin by high cutoff continuous veno‐venous hemodialysis in a patient with rhabdomyolysis: A case report
Abstract Continuous veno‐venous hemodialysis using high cutoff filters (HCO‐CVVHD) is a promising technique, which may be effective to decrease the extremely high level of circulating myoglobin in patients with rhabdomyolysis (RM). Here, we report a patient with RM caused by heat stroke who was successfully treated by HCO‐CVVHD. A male patient received HCO‐CVVHD with 4 L/h dialysate for 5 days and then pre‐dilution continuous veno‐venous hemofiltration (CVVH) at a dose of 4 L/h until recovery of renal function. The clearance of myoglobin and albumin at 5 minutes, and at 4, 12, and 24 hours were calculated. ...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Bunyun Wu, Dehua Gong, Daxi Ji, Bin Xu, Zhihong Liu Tags: Case Report Source Type: research

Life-threatening heat stroke presenting with ST elevations: a report of consecutive cases during the heat wave in Austria in July 2013.
We report a series of four cases (three exertional, one classic heat stroke) during the heat wave of July 2013 in Austria. All of them presented with a core temperature > 41 °C, central nervous dysfunction, acute respiratory and renal failure, disseminated intravascular coagulation, rhabdomyolysis, and severe electrocardiographic changes, two cases even mimicking ST-elevation myocardial infarction. The patients were cooled to normal temperature with the "Arctic sun" external cooling system within hours. Electrocardiographic changes resolved quickly. All patients primarily recovered from multiple organ dysfunction a...
Source: Wiener Klinische Wochenschrift - March 25, 2014 Category: Journals (General) Authors: Lassnig E, Dinkhauser P, Maurer E, Eber B Tags: Wien Klin Wochenschr Source Type: research