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Total 128 results found since Jan 2013.

What Are the Complications of Sickle Cell Trait?
Discussion Sickle cell disease (SCD) is a group of inherited blood disorders where there are abnormal hemoglobin molecules and the red blood cells take on a characteristic sickled shape instead of a rounded shape. Sickled hemoglobin provides an evolutionary advantage of giving the individual increased protection against severe and cerebral malaria. The sickled shape doesn’t move through the vascular system as well and therefore is more likely to aggregate in small vessels causing an increased risk of vaso-occlusive disease, acute chest syndrome, splenic sequestration, and priapism. There is also an increased risk of ...
Source: PediatricEducation.org - September 4, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

How to Tell The Difference Between Heat Stress, Exhaustion, and Stroke
The terminology around heat injuries and illness is often confusing. As extreme heat warnings sweep the U.S., here is what you need to know about heat stress, heat exhaustion, and heat stroke. A 90°F-day might be perfect for the beach. But once you start working your body, whether it’s mowing the lawn, going for a hike, or sprinting to catch the bus, your metabolism ramps up, burning fuel and raising your body’s core temperature. Your heart compensates by pumping blood away from your overheated organs to your skin, where dilating blood vessels can dissipate the heat with the help of evaporating sweat. If yo...
Source: TIME: Health - July 18, 2023 Category: Consumer Health News Authors: Aryn Baker Tags: Uncategorized Climate Is Everything Explainer extreme weather healthscienceclimate Source Type: news

A Small-for-Gestational-Age Infant with MIRAGE Syndrome Who Developed Heat Stroke and Rhabdomyolysis due to Severe Temperature Instability
This report describes heat stroke and rhabdomyolysis caused by anhidrosis as a symptom of MIRAGE syndrome in a small-for-gestational-age (SGA) female neonate born at 32 weeks of gestation (birth weight, 911 g [-3.8 SD]). She developed severe temperature instability with anhidrosis, growth failure, mild developmental delay, hypothyroidism, and intractable enteropathy. On day 156, her temperature reached 42.0°C; her fever persisted for 2 h with prolonged irritability. Her serum creatine kinase level increased to a peak value of 12,716 (normal range, 43-321) IU/L. The clinical feature was diagnosed as rhabdomyolysis caused b...
Source: Neonatology - April 12, 2023 Category: Perinatology & Neonatology Authors: Kana Saito Ryota Nakagawa Satoshi Narumi Hirofumi Ohashi Akiko Ishiguro Kazuhiko Kabe Source Type: research

Incidence of Statin-Associated Adverse Events in Kidney Transplant Recipients
CONCLUSIONS: Statins appear to be generally well-tolerated in kidney transplant recipients. However, statin use might be associated with slightly higher risk of post-transplant diabetes mellitus, cataract, and rhabdomyolysis.PMID:36800538 | DOI:10.2215/CJN.0000000000000124
Source: Clinical Journal of the American Society of Nephrology : CJASN - February 17, 2023 Category: Urology & Nephrology Authors: Sunjae Bae JiYoon B Ahn Kmd Corey Joseph Ryan Whisler Mark A Schnitzler Krista L Lentine Bernard S Kadosh Dorry L Segev Mara A McAdams-DeMarco Source Type: research

What to Know if Your Doctor Put You on Statins to Lower Cholesterol
High cholesterol is a prime example of having too much of a good thing. Our bodies naturally make this substance in the liver and then transport it throughout the body for multiple functions, including hormone regulation, cell tissue regeneration, and vitamin absorption. When the system is working well, cholesterol can boost overall health. But when a certain type called low-density lipoprotein—LDL, sometimes dubbed the “bad” kind—is overproduced, not only does it block the “good” kind called high-density lipoprotein (HDL), but it can also begin to accumulate in the arteries and form thi...
Source: TIME: Health - January 25, 2023 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized healthscienceclimate heart health Source Type: news

James P. Knochel, MD, 1930 –2022
The editorial board of Kidney International would like to  express our heartfelt condolences to the family of Dr. James Knochel, who passed away on April 13, 2022, at the age of 91. Dr. Knochel served as an Associate Editor of Kidney International from 1984–2005. Dr. Knochel had a long and productive career in nephrology and made significant contributi ons to the kidney community. He authored over 200 articles and chapters covering a wide range of topics, including electrolyte disorders, acute kidney injury, rhabdomyolysis, and heat stroke.
Source: Kidney International - June 20, 2022 Category: Urology & Nephrology Tags: Tribute Source Type: research

Novel Use of Seraph-100 ™ Blood Purification Therapy in Heat Stroke
We present a novel case of compassionate use of Seraph filter in a young, healthy active duty service member with heat injury-induced massive inflammatory response. The patient is a previously healthy 26-year-old male with altered mental status, tachycardia, fever to 40.3 °C, and hypotension after losing consciousness during a 4-mile run. He had a history of one heat injury in college and took no medications or supplements. Initial workup demonstrated hemoconcentration, leukocytosis, and hyperkalemia. He was intubated, received isotonic crystalloid fluid, and was admitted to the intensive care unit. The patient developed ...
Source: Military Medicine - May 15, 2022 Category: International Medicine & Public Health Authors: Mary K Miller Robert E Spiller Cristin A Mount Christopher Colombo Maurice I Khayat Source Type: research

Early Acute Kidney Injury in Patients with Non-Traumatic Subarachnoid Hemorrhage who Undergo Catheter Angiography: Incidence, Associated Risk Factors and Impact on Outcome
In the aftermath of SAH, the patient is often exposed to numerous potential renal insults, including, but not limited to, the possible nephrotoxicity of contrast media used for computed tomographic angiography and catheter angiography, other insults related to this endovascular procedure, nephrotoxic medications (crystalloid-induced hyperchloremia for instance), rhabdomyolysis, dehydration, sepsis, cardiomyopathy, sedation-related hypotension, aspiration pneumonia and neurogenic pulmonary edema-related hypoxemia, and brain-kidney crosstalk.
Source: Journal of Stroke and Cerebrovascular Diseases - April 23, 2022 Category: Neurology Authors: Laureen Guillemin, Thomas Goronflot, Hubert Desal, Bertrand Rozec, Karim Lakhal Source Type: research